Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 552324
Title Proline-rich extensin-like receptor kinases mediate damage-triggered immune responses to nematode infections
Author(s) Lozano Torres, J.L.
Event IS-MPMI XVIII Congress, Glasgow, 2019-07-14/2019-07-18
Department(s) Laboratory of Nematology
Publication type Abstract in scientific journal or proceedings
Publication year 2019
Abstract Plant-parasitic nematodes constitute a major threat to global food production. Despite causing considerable damage to host tissue during parasitism, little is known on the role of plant basal immunity in resistance to nematodes. We have recently discovered that suppression of basal immunity to nematodes involves a specific class of surface-localized receptors i.e. proline-rich extensin-like receptor kinases (PERKs). However, the role of PERKs as mediators of damage-triggered basal immunity is not well understood. PERKs are differentially regulated upon infections with cyst and root-knot nematodes. Arabidopsis perk-mutants show increased susceptibility to both cyst and root-knot nematodes. By contrast overexpression of AtPERK-A results in enhanced resistance to cyst nematodes. Furthermore, Arabidopsis lines heterologously overexpressing AtPERK-A homologs also show enhanced resistance to cyst nematode infections. AtPERK-A is strongly induced in nematode feeding sites and neighbouring cells. The basal immune response mediated by PERK-A during nematode infection involves binding of the extracellular domain to polygalacturonic acid and the downstream regulation of innate immune suppressors. We, therefore, conclude that PERKs function as damage-triggered immune receptors during nematode infections and as such can be exploited as a novel source of nematode resistance.
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