Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 552513
Title Phylogenomic investigation of IncI1-I plasmids harboring blaCMY-2 and blaSHV-12 in salmonella enterica and Escherichia coli in multiple countries
Author(s) Castellanos, Luis Ricardo; Graaf-Van Bloois, Linda van der; Donado-Godoy, Pilar; Mevius, Dik J.; Wagenaar, Jaap A.; Hordijk, Joost; Zomer, Aldert L.
Source Antimicrobial Agents and Chemotherapy 63 (2019)7. - ISSN 0066-4804
Department(s) Bacteriology & Epidemiology
Publication type Refereed Article in a scientific journal
Publication year 2019
Keyword(s) Blc - Broiler - Chicken - DeoR - IS1294 - IS26 - ISEcp1 - S. Heidelberg - Salmonella Paratyphi B var. Java - SugE - Tn1721

The objective of this study was to elucidate the genetic and evolutionary relatedness of blaCMY-2- and blaSHV-12-carrying IncI1-I plasmids. Phylogenomic analysis based on core genome alignments and gene presence/absence was performed for different IncI1-I sequence types (STs). Most IncI1-I/ST12 and IncI1-I/ ST231 plasmids had near-identical core genomes. The data suggest that widely occurring blaCMY-2-carrying IncI1-I/ST12 plasmids originate from a common ancestor. In contrast, blaSHV-12 was inserted independently into different IncI1-I/ST231-related plasmids.

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