Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 554005
Title Enrichment of nucleic acids
Author(s) Bau, Haim; Song, Jinzhao; Liu, Changchun; Mauk, Michael; Oost, J. van der; Hegge, J.W.
Source Octrooinummer: WO2019178346, verleend: 2019-09-19.
Department(s) BacGen
Publication type Patent
Publication year 2019
Abstract Provided are methods directed to enriching nucleic acids in a biological sample. These methods, in some embodiments can discriminately enrich the abundance of low-copy nucleic acids relative to higher-copy nucleic acids. In some embodiments, the methods provided can enrich a low-copy number mutant allele associated with a disease state, thus allowing early detection and optimized treatment. In other embodiments, the methods can be used for detection of particular molecules, such as antigens, in a sample.
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