Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 558673
Title Peripheral blood mononuclear cells as a source of cold exposure biomarkers
Author(s) Reynés, Bàrbara; Schothorst, Evert van; Keijer, Jaap; Oliver, Paula; Palou, Andreu
Source Wageningen University
Department(s) WIAS
Human and Animal Physiology
Publication type Dataset
Publication year 2020
Keyword(s) GSE62352 - Mustela putorius furo - PRJNA263901
Abstract Male ferrets, aged 3 months, were divided into two group: one group remained at 22 degrees Celsius, while the other group was acclimatized to 4 degrees Celsius for one week. After sacrification, inguinal and periaortic white adipose tissues were dissected, and peripheral blood mononuclear cells (PBMC) were isolated. The three tissues are used for RNA isolation and subsequent global gene expression profiling using custom Agilent ferret-specific 2x400K microarrays. Data analysis indicated that the cold exposure induce a clear gene expression response of some genes in the inguinal and periaortic white adipose tissue as in PBMC. These genes could be defined as a biomakers of the effect of cold exposure in these cells.
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