Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 559519
Title Structural variants in the great tit genome and their effect on seasonal timing
Author(s) Silva, Vinicius Henrique da
Source Wageningen University. Promotor(en): M.A.M. Groenen; M.E. Visser, co-promotor(en): R.P.M.A. Crooijmans; A.M. Johansson. - Wageningen : Wageningen University - ISBN 9789177605201 - 173
Department(s) Animal Breeding and Genomics
WIAS
Publication type Dissertation, internally prepared
Publication year 2020
Availibility Full text available from 2021-01-24
Abstract

The great tit (Parus major) is a songbird that has been extensively explored in ecological and evolutionary studies, shedding light on the effects of the global warming on nature. Genomic structural variability was never explored in detail in these species. The aim of this thesis was to detect, map, characterize and associate, with seasonal timing, structural variants that are present in the great tit genome such as copy number variations (CNVs) and inversions. First, this thesis presents a genome-wide map of CNV regions in the great tit genome, showing how these variants are associated with genomic architecture underlying their molecular formation. Second, CNVs were associated with breeding timing. Finally, this thesis investigate the genomic complexity of a large inversion in the Chromosome 1A. The inversion is recessive lethal and is inherited twice more than expected from male carriers but are normally inherited from female carriers, suggesting a selfish gene.

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