|Title||Fully automated compound screening in Arabidopsis thaliana seedlings|
|Author(s)||Audenaert, Dominique; Nguyen, Long; Rybel, Bert De; Beeckman, Tom|
|Source||In: Plant Chemical Genomics Humana Press Inc. (Methods in Molecular Biology ) - ISBN 9781627035910 - p. 3 - 9.|
|Publication type||Peer reviewed book chapter|
|Keyword(s)||Arabidopsis thaliana - Automation - High-throughput screening|
High-throughput small molecule screenings in model plants are of great value to identify compounds that interfere with plant developmental processes. In academic research, the plant Arabidopsis thaliana is the most commonly used model organism for this purpose. However, compared to plant cellular systems, A. thaliana plants are less amenable to develop high-throughput screening assays. In this chapter, we describe a screening procedure that is compatible with liquid handling systems and increases the throughput of compound screenings in A. thaliana seedlings.