Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 562307
Title The vertical transmission of antibiotic residues from parent hens to broilers
Author(s) Jansen, Larissa J.M.; Berentsen, Ron J.; Arends, Maura; Berendsen, Bjorn J.A.
Source Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 37 (2020)5. - ISSN 1944-0049 - p. 783 - 792.
DOI https://doi.org/10.1080/19440049.2020.1725147
Department(s) BU Veterinary Drugs
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2020
Keyword(s) antibiotics - egg - feather - LC-MS - Vertical transmission
Abstract

Imprudent and superfluous use of antibiotics contributes to the selection of resistant bacteria, which is a large threat to human health. Therefore analytical procedures have been implemented in the poultry production sector to check if antibiotic treatments are registered, aiming to achieve more prudent use of antibiotics. These methods rely on the analysis of feathers, a matrix in which antibiotic residues persist. However, other routes besides direct administration, through which poultry feathers could contain antibiotic residues, should also be taken into account. In this research the vertical transmission from parent hen to broiler was investigated through a controlled animal study for the antibiotics enrofloxacin, doxycycline and sulfachlorpyridazine. Vertical transmission was observed for all antibiotics to both egg and egg shell. Also it is demonstrated that the transferred antibiotics from parent hen to chick are subsequently excreted via the chick’s droppings. Through this route, the broilers’ environment is contaminated. If eggs are hatched that were taken during treatment of the parent hen, this indirect route and/or the direct vertical transmission can eventually result in the detection of low concentrations of antibiotic residues in the broilers’ feathers at greater age: <50 µg kg−1 for freely extractable residues and <10 µg kg−1 for non-freely extractable residues. No antibiotics were detected in the broilers’ muscle or kidney from 4 weeks of age. This research provides relevant information regarding the possible amount of residues originating from vertical transmission when monitoring matrices such as feathers and broiler droppings in order to stimulate correct use and registration of antibiotics in the poultry sector.

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