|Title||COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology-COMPLOT|
|Author(s)||Willems, Stan B.J.; Zegers, Jaccoline; Bunschoten, Anton; Wagterveld, Martijn; Leeuwen, Fijs W.B. Van; Velders, Aldrik H.; Saggiomo, Vittorio|
|Source||The Analyst 145 (2020)5. - ISSN 0003-2654 - p. 1629 - 1635.|
|Publication type||Refereed Article in a scientific journal|
Plasma microcontact patterning (PμCP) and replica molding were combined to make PDMS/glass microfluidic devices with β-cyclodextrin (β-CD) patterns attached covalently on the glass surface inside microchannels. The supramolecular reactivity, reusability and association constant of β-CD with Cy5-Ad2 was tested by analyzing signal-to-noise ratios of patterns vs. spacing with fluorescence microscopy.