Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Volatile compounds as insect lures: factors affecting release from passive dispenser systems
    Nielsen, Mette Cecilie ; Sansom, Catherine E. ; Larsen, Lesley ; Worner, Susan P. ; Rostás, Michael ; Chapman, Bruce ; Butler, Ruth C. ; Kogel, Willem J. de; Davidson, Melanie M. ; Perry, Nigel B. ; Teulon, David A.J. - \ 2019
    New Zealand Journal of Crop and Horticultural Science 47 (2019)3. - ISSN 0114-0671 - p. 208 - 223.
    homologues - methyl isonicotinate - non-pheromone semiochemical - pest management - release rates - Thysanoptera

    Knowledge about the behaviour of passive dispensers used to release semiochemicals for insect pest management is essential to ensure the efficacy of monitoring and control methods based on the use of the semiochemicals. The release characteristics of different passive dispenser types (commercial sachet, altered commercial sachet, polyethylene bags and cotton rolls) were investigated in the laboratory under various conditions. Using the volatile compound methyl isonicotinate (MI), a known lure for western flower thrips Frankliniella occidentalis (Pergande) and two additional homologues ethyl and n-propyl isonicotinate the effect of loading amount (0.5, 1.0 or 2.5 ml), temperatures (15°C, 25°C or 35°C) and air flow (0.1–0.15 m/s or 0.25–0.3 m/s) were tested in a low-speed laminar-flow wind tunnel. The results showed zero-order release kinetics for all tested dispenser types. Release rate kinetics relies on the type of molecule, dispenser type, and the climatic conditions with temperature being a major determinant of release rate. The results of the release characteristics of the different dispensers are discussed in regards to their practical use under greenhouse and field conditions.

    Territorial cohesion through cross-border landscape policy? The European case of the Three Countries park (BE-NL-DE)
    Brüll, A. ; Wirth, T.M. ; Lohrberg, F. ; Kempenaar, Annet ; Brinkhuijsen, M. ; Godart, M.F. ; Coppens, A. ; Nielsen, M. - \ 2017
    Change and Adaptation in Socio-Ecological Systems 3 (2017)1. - ISSN 2300-3669 - p. 68 - 92.
    Landscapes can be understood as socialecological systems under constant change. In Europe various territorial dynamics pose persistent challenges to maintaining diverse landscapes both as European heritage and in their capacity to provide vital functions and services. Concurrently, under the competence of cohesion policy, the EU is attempting to improve policy making by better policy coordination and respecting regional specifics. This paper explores the question how a policy dedicated to landscape can help to handle territorial change and support territorial cohesion. It presents results and performances of the ESPON applied research study LP3LP: (1) a common landscape policy for the Three Countries Park, across the Dutch, German and Belgium borders, including a spatial landscape vision, a governance proposal of adaptive landscape management, and thematic strategies dealing with green infrastructure, cultural heritage, complementary biomass and quality production; (2) recommendations at the EU level. In discussing the significance of a landscape approach for EU policy,three dimensions of landscape are linked withimportant aspects of territorial cohesion: ‘landscape as asset’ addressing natural-cultural territorial capital as an indigenous base forsmart, sustainable, and inclusivedevelopment;‘landscape as place’ stressing the relevance of landscape for place-based policies; and ‘landscape as common ground’ highlighting its potential for horizontal, vertical, and territorial integration.
    Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis
    Hes, F.J. ; Ruano, D. ; Nieuwenhuis, M. ; Tops, C.M.J. ; Schrumpf, M. ; Nielsen, M. ; Huijts, P.E. ; Wijnen, J. ; Wagner, A. ; Gomet Garcia, E.B. ; Sijmons, R.H. ; Menko, F.H. ; Letteboer, T.G. ; Hoogerbrugge, N. ; Harryvan, J.L. ; Kampman, E. ; Morreau, H. ; Vasen, H.F. ; Wezel, T.G. van - \ 2014
    Journal of Medical Genetics 51 (2014)1. - ISSN 0022-2593 - p. 55 - 60.
    genome-wide association - susceptibility loci - genetic-variants - apc - mutations - hereditary - families - metaanalysis - mechanisms - phenotype
    Background Colorectal adenomatous polyposis is associated with a high risk of colorectal cancer (CRC) and is frequently caused by germline mutations in APC or MUTYH. However, in about 20–30% of patients no underlying gene defect can be identified. In this study, we tested if recently identified CRC risk variants play a role in patients with >10 adenomas. Methods We analysed a total of 16 SNPs with a reported association with CRC in a cohort of 252 genetically unexplained index patients with >10 colorectal adenomas and 745 controls. In addition, we collected detailed clinical information from index patients and their first-degree relatives (FDRs). Results We found a statistically significant association with two of the variants tested: rs3802842 (at chromosome 11q23, OR=1.60, 95% CI 1.3 to 2.0) and rs4779584 (at chromosome 15q13, OR=1.50, 95% CI 1.2 to 1.9). The majority of index patients (84%) had between 10 and 100 adenomas and 15% had >100 adenomas. Only two index patients (1%), both with >100 adenomas, had FDRs with polyposis. Forty-one per cent of the index patients had one or more FDRs with CRC. Conclusions These SNPs are the first common, low-penetrant variants reported to be associated with adenomatous polyposis not caused by a defect in the APC, MUTYH, POLD1 and POLE genes. Even though familial occurrence of polyposis was very rare, CRC was over-represented in FDRs of polyposis patients and, if confirmed, these relatives will therefore benefit from surveillance.
    LP3LP Landscape Policy for the Three Countries Park, Final Report - Atlas of Maps
    Lohrberg, F. ; Wirth, M. ; Brüll, A. ; Nielsen, M. ; Coppens, A. ; Kempenaar, J. ; Brinkhuijsen, M. - \ 2014
    ESPON - 180 p.
    LP3LP Landscape Policy for the Three Countries Park, Final Report – Scientific Report
    Lohrberg, F. ; Wirth, M. ; Brüll, A. ; Nielsen, M. ; Coppens, A. ; Kempenaar, J. ; Brinkhuijsen, M. - \ 2014
    ESPON - 41 p.
    LP3LP Landscape Policy for the Three Countries Park, Final Report – Main Report
    Lohrberg, F. ; Wirth, M. ; Brüll, A. ; Nielsen, M. ; Coppens, A. ; Kempenaar, J. ; Brinkhuijsen, M. - \ 2014
    ESPON
    Contribution of bi-allelic germline MUTYH mutations to early-onset and familial colorectal cancer and to low number of adenomatous polyps: case-series and literature review
    Knopperts, A.P. ; Nielsen, M. ; Niessen, R.C. ; Tops, C.M.J. ; Jorritsma, B. ; Varkevisser, J. ; Wijnen, J. ; Siezen, C.L.E. ; Heine-Bröring, R.C. ; Kranen, H.J. ; Vos, Y.J. ; Westers, H. ; Kampman, E. - \ 2013
    Familial Cancer 12 (2013)1. - ISSN 1389-9600 - p. 43 - 50.
    lynch-syndrome - microsatellite instability - gene-mutations - myh mutations - frequency - identification - feasibility - consumption - carriers - colon
    In the absence of a polyposis phenotype, colorectal cancer (CRC) patients referred for genetic testing because of early-onset disease and/or a positive family history, typically undergo testing for molecular signs of Lynch syndrome in their tumors. In the absence of these signs, DNA testing for germline mutations associated with other known tumor syndromes is usually not performed. However, a few studies in large series of CRC patients suggest that in a small percentage of CRC cases, bi-allelic MUTYH germline mutations can be found in the absence of the MUTYH-associated polyposis phenotype. This has not been studied in the Dutch population. Therefore, we analyzed the MUTYH gene for mutations in 89 patients with microsatellite-low or stable CRC cancer diagnosed before the age of 40 years or otherwise meeting the Bethesda criteria, all of them without a polyposis phenotype. In addition, we studied a series of 693 non-CRC patients with 1-13 adenomatous colorectal polyps for the MUTYH hotspot mutations Y179C, G396D and P405L. No bi-allelic MUTYH mutations were observed. Our data suggest that the contribution of bi-allelic MUTYH mutations to the development of CRC in Dutch non-polyposis patients that meet clinical genetic referral criteria, and to the development of low number of colorectal adenomas in non-CRC patients, is likely to be low.
    Market Integration of Fish in Europe
    Nielsen, M. ; Smit, J.G.P. ; Guillen, J. - \ 2009
    Journal of Agricultural Economics 60 (2009)2. - ISSN 0021-857X - p. 367 - 385.
    This paper examines market integration between fish species in Europe, taking international market integration into account. Based on Juselius (2006), market integration is found both on the fresh and frozen markets. The Law of One Price is in force on the fresh market within the segments of flatfish and pelagic fish. Assuming transitivity, a loose form of market integration is identified between 13 fresh and seven frozen fish species, and the relative prices are found fairly stable. The policy implication is that catch limitation measures implemented through the Common Fisheries Policy have limited and conditional effects on prices, because of the large size of the market and varying market integration. Therefore, many fishermen are not 'compensated' by price increases as a result of catch limitation measures.
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