Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

  • help
  • print

    Print search results

  • export

    Export search results

  • alert
    We will mail you new results for this query: metisnummer==1035330
Check title to add to marked list
Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health
Verkerk, R. ; Schreiner, M. ; Krumbein, A. ; Ciska, E. ; Holst, B. ; Rowland, I. ; Schrijver, R. de; Hansen, M. ; Gerhäuser, C. ; Mithen, R. ; Dekker, M. - \ 2009
Molecular Nutrition & Food Research 53 (2009)S2. - ISSN 1613-4125 - p. S219 - S265.
glutathione-s-transferase - oleracea var. italica - colon-cancer cells - aberrant crypt foci - naturally-occurring isothiocyanate - phase-2 detoxification enzymes - plant-derived biomolecules - natural substance class - rapeseed meal toxicity - oxidative dna-damag
Glucosinolates (GLSs) are found in Brassica vegetables. Examples of these sources include cabbage, Brussels sprouts, broccoli, cauliflower and various root vegetables (e.g. radish and turnip). A number of epidemiological studies have identified an inverse association between consumption of these vegetables and the risk of colon and rectal cancer. Animal studies have shown changes in enzyme activities and DNA damage resulting from consumption of Brassica vegetables or isothiocyanates, the breakdown products (BDP) of GLSs in the body. Mechanistic studies have begun to identify the ways in which the compounds may exert their protective action but the relevance of these studies to protective effects in the human alimentary tract is as yet unproven. In vitro studies with a number of specific isothiocyanates have suggested mechanisms that might be the basis of their chemoprotective effects. The concentration and composition of the GLSs in different plants, but also within a plant (e.g. in the seeds, roots or leaves), can vary greatly and also changes during plant development. Furthermore, the effects of various factors in the supply chain of Brassica vegetables including breeding, cultivation, storage and processing on intake and bioavailability of GLSs are extensively discussed in this paper
Check title to add to marked list

Show 20 50 100 records per page

Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.