Genome sequence and analysis of the tuber crop potato
Xu, X. ; Pan, S.K. ; Cheng, S.F. ; Zhang, B. ; Bachem, C.W.B. ; Boer, J.M. de; Borm, T.J.A. ; Kloosterman, B.A. ; Eck, H.J. van; Datema, E. ; Goverse, A. ; Ham, R.C.H.J. van; Visser, R.G.F. - \ 2011
Nature 475 (2011). - ISSN 0028-0836 - p. 189 - 195.
eukaryotic genomes - resistance genes - in-vitro - rna-seq - solanum - tool - identification - elements - reveals - maize
Potato (Solanum tuberosum L.) is the world’s most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop