Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Invloed van transport op de stressfysiologie van marktwaardige Afrikaanse meerval en Europese paling
    Vis, J.W. van de; Schram, E. ; Boerrigter, J. ; Manuel, R. ; Heul, J.W. van der; Bos, R. van den; Hofman, A.R.T. ; Ros, N.A.M. ; Lambooij, E. ; Flik, G. - \ 2013
    IJmuiden : IMARES Wageningen UR (Rapport / IMARES Wageningen UR C100/13) - 28
    stressfysiologie - clarias gariepinus - european eels - transport - laesies - bloedplasma - visserij - dierenwelzijn - stress physiology - clarias gariepinus - european eels - transport - lesions - blood plasma - fisheries - animal welfare
    Het onderzoek was gericht op effecten van praktijkgerichte transportcondities van marktwaardige Afrikaanse meerval (Clarias gariepinus) en Europese paling (Anguilla anguilla) op de relevante fysiologische parameters in het bloedplasma (cortisol, glucose en niet-veresterde vrije vetzuren) en mogelijke laesies van de huid.
    Investigation into blood plasma in milk formula
    Raamsdonk, L.W.D. van; Scholtens-Toma, I.M.J. ; Ossenkoppele, J.S. ; Egmond, H.J. van; Groot, M.J. - \ 2011
    Wageningen : Rikilt - Institute of Food Safety (Report / RIKILT 2011.003) - 19
    bloedplasma - melk - voersamenstelling - taptemelk - dierlijke eiwitten - blood plasma - milk - feed formulation - skim milk - animal proteins
    In July 2010 a rapid alert was issued by Spain concerning the presence of blood plasm in milk formula ("KUOVO") for calves. The blood plasma was detected by a microscopic staining method using tetramethylbenzidine (TMB). RIKILT investigated the suspect research sample by applying the standard research method for animal proteins and several additional staining methods, including TMB (macroscopic and microscopic).
    Bioavailability of flavonoids and cinnamic acids and their effect on plasma homosysteine in humans
    Olthof, M.R. - \ 2001
    Wageningen University. Promotor(en): M.B. Katan; P.C.H. Hollman. - S.l. : S.n. - ISBN 9789058084170 - 135
    flavonoïden - kaneelzuur - homocysteïne - bloedplasma - biologische beschikbaarheid - mens - quercetine - theaflavine - chlorogeenzuur - hart- en vaatziekten - flavonoids - cinnamic acid - homocysteine - blood plasma - bioavailability - man - quercetin - theaflavine - chlorogenic acid - cardiovascular diseases

    Dietary antioxidants might prevent oxidative damage to tissues and therefore protect against cardiovascular disease and cancer. Dietary phenols are strong antioxidants in vitro but their role in vivo is uncertain. Furthermore, there are only limited data on their bioavailability in humans. The aim of this thesis was to investigate whether bioavailability data on flavonoids and cinnamic acids support the hypothesis that they can affect health in humans . Because the group of phenols in foods is huge, we focussed our research on major phenols in foods; the flavonol quercetin, black tea phenols and chlorogenic acid (5-caffeoylquinic acid). We studied their bioavailability and effect on plasma homocysteine in humans, a potential risk factor for cardiovascular disease.

    The bioavailability of quercetin and chlorogenic acid depends upon their conjugated moieties. Hollman et al. found that the bioavailability of quercetin-3-rutinoside, a major flavonol in tea, was only 20% of that of quercetin-4'-glucoside. We found that transformation of quercetin-3-rutinoside into quercetin-3-glucoside will improve its bioavailability because the 3-glucoside had the same high bioavailability as the 4'-glucoside. Caffeic acid is a major phenol in coffee, but it is present as a conjugate with quinic acid, called chlorogenic acid. We found that the conjugation of caffeic acid with quinic acid hinders absorption in humans: absorption of chlorogenic acid was only 30% of that of its caffeic acid moiety.

    Furthermore, we found that chlorogenic acid, black tea solids and quercetin-3-rutinoside are extensively metabolized in the human body, mainly before they reach the circulation. Their metabolites have no, or less, antioxidant activity in vitro than their parent phenols. Therefore the role of dietary phenols as antioxidants in vivo might be less important than suggested by their in vitro antioxidant activity.

    Coffee consumption increases plasma homocysteine, a potential risk factor for cardiovascular disease. Chlorogenic acid from coffee is partly responsible for the homocysteine-raising effect of coffee, because we found that it increased plasma homocysteine. Black tea solids also raised plasma homocysteine, whereas quercetin-3-rutinoside did not. Furthermore, we found that glycination of metabolites of phenols in the body is not involved in the homocysteine-raising effect of phenols.

    In conclusion, chlorogenic acid, tea phenols and quercetin are available in the human body, but their effects on health are uncertain. Further research on bioavailability and health effects of dietary phenols is needed.

    Bloedplasma en bloedcellen in voer voor gespeende biggen
    Peet-Schwering, C.M.C. van der; Binnendijk, G.P. - \ 1997
    Rosmalen : Praktijkonderzoek varkenshouderij (Proefverslag / Praktijkonderzoek Varkenshouderij P1.168) - 20
    diervoedering - experimenten - spenen - bloedplasma - bloedserum - biggen - animal feeding - experiments - weaning - blood plasma - blood serum - piglets
    Bloedplasma en bloedcellen in voer voor biggen
    Peet-Schwering, C. van der; Binnendijk, G. - \ 1997
    Praktijkonderzoek varkenshouderij 11 (1997)1. - ISSN 1382-0346 - p. 12 - 13.
    dierhouderij - bloed - bloedcellen - bloedplasma - bloedserum - samenstelling - ontwikkeling - voer - groei - biggen - productiviteit - rentabiliteit - spenen - animal husbandry - blood - blood cells - blood plasma - blood serum - composition - development - feeds - growth - piglets - productivity - profitability - weaning
    Speenvoer met 5% bloedplasma, dat gedurende de eerste acht dagen van de opfokperiode verstrekt wordt, verbetert in die periode de technische resultaten van de biggen.
    Characterisation of fish leucocytes : an immunocytochemical and functional study in carp (Cyprinus carpio L.)
    Koumans - van Diepen, J.C.E. - \ 1993
    Agricultural University. Promotor(en): W.B. van Muiswinkel, co-promotor(en): J.H.W.M. Rombout. - S.l. : Koumans-van Diepen - ISBN 9789054851110 - 167
    cyprinidae - karper - bloedserum - fibrine - bloedplaatjes - bloed - erytrocyten - leukocyten - bloedplasma - reticulo-endotheliaal systeem - antilichamen - immunoglobulinen - immunocytochemie - cyprinidae - carp - blood serum - fibrin - platelets - blood - erythrocytes - leukocytes - blood plasma - reticuloendothelial system - antibodies - immunoglobulins - immunocytochemistry

    A panel of monoclonal antibodies (MAbs) against carp serum immunoglobulin (Ig), WCIs or carp thymocytes (T), WCTs were used for the characterisation of carp leucocytes. Unfortunately, all WCTs and some WCIs react with common carbohydrate determinants present on all leucocytes and Ig. Most WCIs react specific with protein determinants at the heavy chain of Ig. Consequently, B lymphocyte (sub) populations, plasma cells and Ig-binding cells could be studied. Ig molecules are found in clusters at the cell membrane of B cells and plasma cells, and in contrast to mammalian plasma cells, most carp plasma cells still have Ig at their surface membrane. Mainly the dull surface Ig-positive (sIg +) cells were stimulated by the mammalian B cell mitogen LPS and not by PHA (T cell mitogen) in vitro , whereas the sIg-negative (sIg -) cells were stimulated by PHA and not by LPS. The percentages of B cells and plasma cells showed an increase during ontogeny and reached a plateau at about 3 months and 8 months of age respectively. It is suggested that full development of the carp (humoral) immune system needs at least 8 months (at 21-22 °C). Three different subpopulations of B cells and plasma cells and at least two Ig isotypes can be distinguished based upon their reactivity with WCI 4 arid WCI 12. The distribution of the three B cell subpopulations appeared to be organ and age dependent which indicates functional differences between the Ig isotypes. Fc-like receptors were mainly demonstrated on gut macrophages while pronephros macrophages and neutrophilic granulocytes did not show Ig binding. Consequently, other forms of antigen opsonisation (e.g. complement) may play a role in phagocytosis by these non Ig-binding cells. Several procedures were tested for obtaining MAbs specific for Ig -lymphoid cells. It is concluded that the presence of immunodominant carbohydrate determinants is the major problem for obtaining specific MAbs. Tolerisation of mice against these determinants or the use of isolated membrane lysates from (sIg -) PBL appeared promising but till now only specific thrombocyte markers have been obtained. The use of more purified antigen is recommended in further attempts. The data presented in this thesis can be used for fundamental studies on cell interactions in the immune response, but also for more applied investigations on fish health control.

    Bepaling van chlooramphenicol in urine, gal, lever etc.
    Beek, W.M.J. ; Buizer, F.G. - \ 1982
    Wageningen : RIKILT (Verslag / RIKILT 82.81) - 3
    chlooramfenicol - bloedplasma - bloedserum - hplc - analytische methoden - vloeistofchromatografie - organen - urine - chloramphenicol - blood plasma - blood serum - hplc - analytical methods - liquid chromatography - organs - urine
    Het bepalen van chlooramphenicol in monsters urine, gal, nier etc , welke afkomstig zijn van de Vleeskeuringsdient Nijmegen, met behulp van Interne Analysemethoden. De monsters werden onderzocht volgens intern analysevoorschrift nr. Dgm 26: Bepaling van chlooramphenicol in bloed, plasma, serum etc. door middel van HPLC. Met enige wijzigingen konden ook hiermede vlees, lever etc. onderzocht worden.
    Progesteronebepaling in plasma : ontwikkeling van de radio - immunologische bepalingsmethodiek en meting van de normaalwaarden bij het Nederlandse landvarken
    Koops, W. ; Wiel, D.F.M. van de - \ 1978
    varkens - zoölogie - progesteron - bloedplasma - immunologische technieken - pigs - zoology - progesterone - blood plasma - immunological techniques
    De invloed van nuchterheid op de concentratie van NEFA in het bloedplasma van varkens
    Wal, P.G. van der; Boxtel, H.L. ; Vos, E.M. - \ 1970
    Zeist : I.V.O. (Rapport / Instituut voor Veeteeltkundig Onderzoek "Schoonoord" no. C 141) - 7
    bloedplasma - bloedserum - varkens - diergeneeskunde - zoölogie - blood plasma - blood serum - pigs - veterinary science - zoology
    Enkele variabelen bij de bepaling van Lact. Dehydrogenase (LDH) in varkensplasma
    Zuidam, L. ; Heykoop, L. - \ 1969
    Zeist : I.V.O. (Rapport / Instituut voor veeteeltkundig onderzoek "Schoonoord" no. C 139) - 6
    bloedplasma - bloedserum - varkens - diergeneeskunde - zoölogie - blood plasma - blood serum - pigs - veterinary science - zoology
    Genetical and some environmental influences affecting the level of leucocyte counts in the milk of cows
    Afifi, Y.A. - \ 1967
    Wageningen University. Promotor(en): T. Stegenga. - Wageningen : Veenman - 81
    rundvee - rauwe melk - diergeneeskunde - melkklieren - melksecretie - lactatie - dierlijke producten - vervalsing - besmetting - verouderen - gebreken - achteruitgang (deterioration) - bloedserum - fibrine - bloedplaatjes - bloed - erytrocyten - leukocyten - bloedplasma - mastitis - cattle - raw milk - veterinary science - mammary glands - milk secretion - lactation - animal products - adulteration - contamination - aging - defects - deterioration - blood serum - fibrin - platelets - blood - erythrocytes - leukocytes - blood plasma - mastitis
    The progeny groups of different sires varied widely in white-cell count in milk, even after exclusion of all cows which had suffered from mastitis. The sire had a demonstrable effect on white-cell count in milk, especially during the second half of lactation. Heritability estimates of white-cell count in milk showed that values for the fourth lactation were higher than those for heifers. But at the end of lactation heritability values for 4th lactation cows and heifers were nearly equal (about 0.40). The daughter groups with high average white-cell counts mostly showed frequent mastitis. There was a high phenotypic and genetic correlation between clinical mastitis and white-cell count. Within seasons for cows which, so far known, had never mastitis, very high and very low producers had higher white-cell counts than other cows. White-cell counts increased remarkably with advancing lactation. A relation between white-cell count and ease of milking could not be demonstrated.

    Increasing milking vacuum over 40 cm mercury pressure, especially at the end of lactation, or increasing pulsation to over 50 per min. tended to increase white-cells. Milking routine (man/machine ratio) affected white-cell count in the end of lactation. More cows per milker increased the number of white-cells.

    Verspreiding van bloedgroepen in het Nederlandse zwartbonte rundvee : een onderzoek naar de frequenties van bloedgroepen en naar enige factoren, die de frequenties beinvloeden
    Kraaij, G.J. - \ 1967
    Wageningen University. Promotor(en): T. Stegenga. - Wageningen : Veenman - 127
    bloedserum - fibrine - bloedplaatjes - bloed - erytrocyten - leukocyten - bloedplasma - rundvee - melkveerassen - nederland - genetica - heritability - genetische variatie - blood serum - fibrin - platelets - blood - erythrocytes - leukocytes - blood plasma - cattle - dairy breeds - netherlands - genetics - heritability - genetic variation
    Blood groups are genetically determined components of the red blood cells. In cattle there were 13 loci known to determine blood groups and some of these loci had large series of alleles. There were also 14 other loci known to determine proteins and enzymes in blood and milk of cattle.

    The author examined how the distribution of blood groups in the Dutch Friesian population had been influenced by the restrictions of breeders. He found that parent cattle were paired independently of blood group. In offspring there was no selection for a certain phenotype until the end of the first year.

    There were clear differences in the frequency of some genes between adult bulls and cows. The gene for blood group A was less frequent in bulls and that for blood group F was less frequent in cows. This occurred in some foreign breeds of cattle.

    The distribution of blood groups over the population was not even. There were differences in gene frequency between breeding areas and in the breeding areas there were large differences between artificial insemination stations. Differences within farms and within breeding pedigrees were even greater. These differences could be ascribed largely to the use of one or only a few sires.

    Het kopergehalte van lever en bloedserum bij het Fries-Hollandse rund
    Grift, J. van der - \ 1955
    's-Gravenhage : Staatsdrukkerij (Verslagen van landbouwkundige onderzoekingen 61.10) - 61
    melkveerassen - rundvee - bloedserum - fibrine - bloedplaatjes - bloed - erytrocyten - leukocyten - bloedplasma - dairy breeds - cattle - blood serum - fibrin - platelets - blood - erythrocytes - leukocytes - blood plasma
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