Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    We will mail you new results for this query: keywords==Quality of life
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A longitudinal mixed methods study on changes in body weight, body composition, and lifestyle in breast cancer patients during chemotherapy and in a comparison group of women without cancer : Study protocol
Kruif, J.Th.C.M. De; Visser, M. ; Berg, M.M.G.A. Van Den; Derks, M.J.M. ; Boer, M.R. De; Laarhoven, H.W.M. Van; Vries, J.H.M. De; Vries, Y.C. De; Kampman, E. ; Winkels, R.W. ; Westerman, M.J. - \ 2019
BMC Cancer 19 (2019)1. - ISSN 1471-2407
Body composition - Body weight - Breast cancer - Dietary intake - Mixed methods - Perceptions - Physical activity - Quality of life

Background: More than 60% of women diagnosed with early stage breast cancer receive (neo)adjuvant chemotherapy. Breast cancer patients receiving chemotherapy often experience symptoms such as nausea, vomiting and loss of appetite that potentially affect body weight and body composition. Changes in body weight and body composition may detrimentally affect their quality of life, and could potentially increase the risk of disease recurrence, cardiovascular disease and diabetes. To date, from existing single method (quantitative or qualitative) studies is not clear whether changes in body weight and body composition in breast cancer patients are treatment related because previous studies have not included a control group of women without breast cancer. Methods: We therefore developed the COBRA-study (Change Of Body composition in BReast cancer: All-in Assessment-study) to assess changes in body weight, body composition and related lifestyle factors such as changes in physical activity, dietary intake and other behaviours. Important and unique features of the COBRA-study is that it used I) a "Mixed Methods Design", in order to quantitatively assess changes in body weight, body composition and lifestyle factors and, to qualitatively assess how perceptions of women may have influenced these measured changes pre-, during and post-chemotherapy, and II) a control group of non-cancer women for comparison. Descriptive statistics on individual quantitative data were combined with results from a thematic analysis on the interviews- and focus group data to understand patients' experiences before, during and after chemotherapy. Discussion: The findings of our mixed methods study, on chemotherapy treated cancer patients and a comparison group, can enable healthcare researchers and professionals to develop tailored intervention schemes to help breast cancer patients prevent or handle the physical and mental changes they experience as a result of their chemotherapy. This will ultimately improve their quality of life and could potentially reduce their risk for other co-morbidity health issues such as cardiovascular disease and diabetes.

Beyond scarcity perspectives on energy transition
Geerts, Robert Jan - \ 2018
Relations 6 (2018)1. - ISSN 2283-3196 - p. 49 - 68.
Abundance - Energy debates - Energy discourse - Energy ethics - Energy transition - Good life - Prosperity - Quality of life - Scarcity - Simplicity

Two dominant lines of reasoning in the philosophical debate on energy transition can be described as boundless consumerism (we should find ways to keep growing) and eco-frugality (we should reduce our impact as much as possible). This paper problematizes both approaches via their implicit understanding of the good life, and proposes a third alternative: qualitative abundance. Society is not interested in any sustainable energy system, but in one that caters to our needs and enables us to flourish as human beings. Because the dominant lines in the current debate share a concern for scarcity, they fail to raise the question of a "good" energy system, and therefore the possibility of a positive energy ethics. Qualitative abundance initiates discourse around prosperity (with boundless consumerism) and simplicity (with ecofrugality), thus expanding and enriching debates on energy transition.

Taste and smell perception and quality of life during and after systemic therapy for breast cancer
Vries, Y.C. de; Boesveldt, S. ; Kelfkens, C.S. ; Posthuma, E.E. ; Den Berg, M.M.G.A. van; Kruif, J.T.C.M. de; Haringhuizen, A. ; Sommeijer, D.W. ; Buist, N. ; Grosfeld, S. ; Graaf, C. de; Laarhoven, H.W.M. van; Kampman, E. ; Winkels, R.M. - \ 2018
Breast Cancer Research and Treatment 170 (2018)1. - ISSN 0167-6806 - p. 27 - 34.
Breast cancer - Chemotherapy - Dysgeusia - Herceptin - Quality of life - Smell - Taste - Taste loss - Trastuzumab
Purpose: The purpose of the study was to assess self-reported taste and smell perception after chemotherapy in breast cancer patients compared with women without cancer, and to assess whether taste and smell perception is associated with quality of life after the end of chemotherapy. Methods: We included 135 newly diagnosed breast cancer patients who completed chemotherapy and 114 women without cancer. Questionnaires on taste, smell, and quality of life were completed shortly after and 6 months after chemotherapy (patients) or at two moments with 6 months’ time window in between (comparisons). Results: Self-reported taste and smell perception were significantly lower in patients shortly after chemotherapy compared to the comparison group. Most patients recovered 6 months after chemotherapy, although patients who were still receiving trastuzumab then reported a lower taste and smell perception compared to patients who were not. A lower self-reported taste and smell were statistically significantly associated with a worse quality of life, social, emotional, and role functioning shortly after chemotherapy. Six months after chemotherapy, taste and smell were statistically significantly associated with quality of life, social and role functioning, but only in patients receiving trastuzumab. Conclusions: Most taste and smell alterations recovered within 6 months after the end of chemotherapy for breast cancer, but not for patients receiving trastuzumab. These results highlight the importance of monitoring taste and smell alterations during and after treatment with chemotherapy and trastuzumab, as they may impact quality of life.
Evaluating quality of life and response shift from a couple-based perspective : a study among patients with colorectal cancer and their partners
Traa, Marjan J. ; Braeken, Johan ; Vries, Jolanda De; Roukema, Jan A. ; Orsini, Ricardo G. ; Oudsten, Brenda L. Den - \ 2015
Quality of Life Research 24 (2015)6. - ISSN 0962-9343 - p. 1431 - 1441.
Colorectal cancer - Dyadic - Measurement invariance - Partners - Quality of life - Response shift

Objectives: To examine (1) measurement invariance of quality of life (QoL) domains over time for patients with colorectal cancer and partners (i.e., response shift—recalibration, reprioritization, and reconceptualization), (2) between dyad-member measurement invariance and (3) QoL trajectories. Methods: Participants completed the WHOQOL-Bref preoperative (Time-0) and 3 (Time-1) and 6 months (Time-2) postoperative. A stepwise procedure, using nested factor models, examined the viability of restricting specific model parameters to be equal across measurements and between dyad members. Findings: No reconceptualization and reprioritization was detected, but indications for recalibration were present. Therefore, comparisons were restricted to group-level statistics at factor level. For patients, a decrease in the Physical Health domain occurred at Time-1 (p 0.05) and were at each time point higher than patients’ factor means (p’s 0.05). Patients and partners’ factor means were comparable (p’s > 0.05). Patients and partners’ Social Relationship factor means decreased at Time-1 (p’s 0.05). Conclusion: Since both patients and partners are affected by the patients’ disease and treatment, we recommend that attention is paid to the couple instead of solely the patient.

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