Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    We will mail you new results for this query: keywords==haemoglobin
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Effect of vitamin B12 and taurine on the alleviation of nutritional anaemia in common sole (Solea solea)
Kals, Jeroen ; Blonk, Robbert J.W. ; Mheen, Henk W. van der; Schrama, Johan W. ; Verreth, Johan A.J. - \ 2019
Aquaculture Nutrition 25 (2019)2. - ISSN 1353-5773 - p. 456 - 465.
anaemia - haematocrit - haemoglobin - sole (Solea solea) - taurine - vitamin B12
Sole fed commercial pellets develop a nutritional anaemia. This study assessed the impact of dietary B12 and taurine on the haematocrit (Hct) and haemoglobin (Hb) level and mineral absorption in anaemic sole. Anaemic sole was fed one of four diets. Diets were equal regarding mineral, amino acid and macronutrient composition and formulated, according to a two by two factorial design: two B12 (0.34 vs. 1.9 mg kg dm) and two taurine levels (3.5 vs. 7.6 mg kg dm−1). The feeding level was restricted and equal for all diets. Hct and Hb levels in anaemic sole are influenced by dietary B12. A “high” level of B12 increases the Hct and Hb level. An increasing level of taurine suppresses the stimulating effect of the “high” level of B12. The applied B12 and taurine levels were unable to completely alleviate the anaemia in sole. Nevertheless, sole needs high dietary levels of B12 to alleviate anaemia. The impact of B12 and taurine on Hb and Hct was not related to a change in the absorption of iron. A “high” level of B12 positively affected the absorption of chromium and a high level of taurine negatively affected the absorption of cobalt in sole.
The development of a sole diet based on the composition of ragworm
Kals, Jeroen - \ 2017
Wageningen University. Promotor(en): J.A.J. Verreth, co-promotor(en): J.W. Schrama; R.J.W. Blonk. - Wageningen : Wageningen University - ISBN 9789463431804 - 136
dover soles - annelida - fish feeding - anaemia - haemoglobin - fish culture - aquaculture - tong (vis) - annelida - visvoeding - anemie - hemoglobine - visteelt - aquacultuur

Scientifically, this study aimed to validate the potential of ragworm to alleviate anaemia in common sole and to identify the dietary requirements of common sole to alleviate this anaemia. At the same time it was aimed to explain part of the difference in growth between sole fed a commercial pellet and sole fed ragworm. Practically, this study aimed to develop a diet that achieves similar growth rates in sole as when fed ragworm. Sole fed commercial pellets developed nutritional anaemia. Feeding ragworm or mussel alleviates this nutritional anaemia. It is suggested that the ability of mussel or ragworm (meal) to alleviate anaemia and improve growth in sole can be explained by heme iron and high B12 levels. Yet, iron absorption in sole is high and independent of iron source. Still, heme increases the absorption of copper. The high absorption of iron and copper in sole fed heme does not affect the haematocrit (Hct) and haemoglobin (Hb) levels, which indicates the anaemia in sole is not an iron or a copper deficiency anaemia. The Hct and Hb levels in sole are affected by dietary B12. Yet, the applied levels are unable to alleviate the anaemia in sole induced by feeding commercial pellets. More options to alleviate the nutritional anaemia in common sole are discussed. Nutrients as vitamin C, B1, B2, B5 and a possible role of dietary EPO are discussed. It is suggested that the slow growth of pellet-fed sole might be due to the low Hct and Hb levels, which hampers the uptake of oxygen, and thus also the overall metabolic capacity, including the scope for growth. Discussed is a 7°C difference in the “optimal” temperature between sole fed ragworm and the 2nd generation pellet and that the “worm effect” is dependent on temperature. However, the growth rate of sole fed the 3rd generation pellet at 18.4°C was comparable to the growth rate of sole fed ragworm, which could not have been the consequence of increasing Hct and Hb levels as these were comparable to levels found in sole fed commercial pellets. Yet, B12 levels in blood plasma of sole are up to 200 times those of other (fish) species. Hence, we inferred on the possibility of a specific metabolic function of B12 in respiration in sole. In addition, the economic and practical impact of the improved growth rate in sole culture is discussed. Finally, several suggestions for future research are given.

Ontwikkeling van een detectiemethode voor hemoglobine-addukten, nitro-polycyclische aromatische koolwaterstoffen en metabolieten met behulp van gaschromatografie-massaspectrometrie
Zuidema, T. ; Traag, W.A. - \ 1994
Wageningen : DLO-Rijks-Kwaliteitsinstituut voor Land- en Tuinbouwprodukten (Rapport / RIKILT-DLO 94.07) - 16
hemoglobine - derivaten - organische stikstofverbindingen - metabolieten - gc-ms - polycyclische aromatische koolwaterstoffen - haemoglobin - derivatives - organic nitrogen compounds - metabolites - polycyclic aromatic hydrocarbons
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