Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Can bacteria in your gut prevent diseases? The health implications of microbiota | WURcast
    Belzer, C. - \ 2019
    Wageningen : WURcast
    gastrointestinal microbiota - human diseases - prediction - disease prevention
    Lokschapen vangen teken in het bos
    Sikkema, A. ; Wieren, S.E. van - \ 2014
    Wageningen UR/Stichting voor Duurzame Ontwikkeling
    schapen - gastheer parasiet relaties - vangmethoden - lokken - natuurgebieden - borrelia burgdorferi - humane ziekten - lyme-ziekte - infectieziekten - insecticiden - experimenten - wetenschappelijk onderzoek - bosecologie - sheep - host parasite relationships - trapping - baiting - natural areas - borrelia burgdorferi - human diseases - lyme disease - infectious diseases - insecticides - experiments - scientific research - forest ecology
    De Wageningse onderzoeker Sip van Wieren wil lokschapen inzetten om teken weg te vangen in natuurgebieden. Op die manier kunnen schaapskuddes er voor zorgen dat mensen prettig kunnen recreëren in het bos.
    Lokschapen tegen teken
    Wieren, S.E. van - \ 2014
    Wageningen UR
    schapen - gastheer parasiet relaties - lokken - humane ziekten - lyme-ziekte - vangmethoden - experimenten - natuurgebieden - bosecologie - sheep - host parasite relationships - baiting - human diseases - lyme disease - trapping - experiments - natural areas - forest ecology
    Teken vormen een lastig probleem voor bezoekers van natuurterreinen en bossen. Onderzoekers gaan nu met ‘lokschapen’ teken vangen.
    Coxiella burnetii in pregnant goats
    Roest, H.I.J. - \ 2013
    Wageningen University. Promotor(en): J.P.M. van Putten, co-promotor(en): Annemarie Rebel; Alex Bossers. - s.n. - ISBN 9789064646423 - 197
    q-koorts - coxiella burnetii - humane ziekten - geiten - geitenhouderij - dierenwelzijn - q fever - coxiella burnetii - human diseases - goats - goat keeping - animal welfare
    Coxiella burnetii is the causative agent of Q fever. Since it was first recognised as a disease in the 1930s, knowledge about the agent and the disease itself has increased, although knowledge gaps are still present. Therefore the name Q(uery) fever still holds true.
    Ziekte van Lyme : nasleep van een tekenbeet
    Broek, P. ; Takken, W. - \ 2012
    Den Haag : Stichting Bio-Wetenschappen en Maatschappij (Cahier / Bio-Wetenschappen en Maatschappij 31e jrg. (2012), nr. 1) - ISBN 9789073196667 - 67
    lyme-ziekte - ziekten overgebracht door teken - humane ziekten - tekenbeten - volksgezondheid - gezondheidsgevaren - ziektepreventie - diagnose - wetenschappelijk onderzoek - lyme disease - tickborne diseases - human diseases - tick bites - public health - health hazards - disease prevention - diagnosis - scientific research
    Dit themanummer beschrijft de Ziekte van Lyme en geeft een overzicht over de stand van kennis over deze complexe ziekte in Nederland. De lymeziekte is uniek omdat zij veroorzaakt wordt door een bacterie die een teek als tussengastheer (vector) gebruikt.
    AIDS and Rural Livelihoods. Dynamics and Diversity in Sub-Saharan Africa
    Niehof, Anke ; Rugalema, G. ; Gillespie, S. - \ 2010
    London : Earthscan - ISBN 9781849711265 - 234
    ontwikkelingsstudies - acquired immune deficiency syndrome - humane ziekten - hiv-infecties - volksgezondheid - platteland - plattelandsbevolking - sociale economie - rurale sociologie - economische aspecten - afrika ten zuiden van de sahara - landbouwhuishoudens - development studies - acquired immune deficiency syndrome - human diseases - hiv infections - public health - rural areas - rural population - socioeconomics - rural sociology - economic aspects - africa south of sahara - agricultural households
    HIV and AIDS continue to devastate the livelihoods of millions of Africans and represent the major public health challenge in many countries. More people die of AIDS each day than from wars, famine and floods combined, while an orphaned generation of children must be provided for. Yet despite millions of dollars of aid and research, there has previously been little detailed on-the-ground analysis of the long-term impact on rural people. This book brings together recent evidence on HIV/AIDS impacts on rural households, livelihoods, and agricultural practice in sub-Saharan Africa. There is particular emphasis on the role of women in affected households. The book presents micro-level information collected by original empirical research in a range of African countries, and shows how well-grounded conclusions on trends and major problems can then be addressed by policies. It is shown that HIV/AIDS impacts are more diverse than we know (and not always negative) on the basis of cumulative evidence so far.
    Vaccinatie moet Q-koorts stoppen
    Roest, H.I.J. - \ 2009
    Kennis Online 6 (2009)juni. - p. 3 - 3.
    veehouderij - q-koorts - coxiella burnetii - infectieziekten - humane ziekten - vaccinatie - geitenziekten - geiten - livestock farming - q fever - coxiella burnetii - infectious diseases - human diseases - vaccination - goat diseases - goats
    Hendrik-Jan Roest van het Centraal Veterinair Instituut (CVI) houdt de Q-koorts voor de ministeries van LNV en VWS in de gaten en geeft de stand van zaken weer
    Insects and disease in the 21st century : a wind of change
    Takken, W. - \ 2008
    Wageningen : Wageningen UR - ISBN 9789085852278 - 31
    insecten - ziekten - infectieziekten - humane ziekten - dierziekten - vectoren, ziekten - ziekten overgebracht door vectoren - openbare redes - insects - diseases - infectious diseases - human diseases - animal diseases - disease vectors - vector-borne diseases - public speeches
    In recent years, several other vectors have become world news: the sheep tick was discovered to be the vector of Lyme disease in 1980; the mosquito Culex pipiens began transmitting West Nile virus in North America in 1999; in August 2006, bluetongue virus was discovered in Belgium and the Netherlands, transmitted by biting midges and in 2007, Asian tiger mosquitoes began transmitting Chikungunya virus in northern Italy. Other anecdotes that are worthwhile mentioning, but not very good news because of their potential impact on our society: recorded cases of canine babesiosis in the Netherlands (Nijhof et al. 2007); the establishment of the tick Dermacentor reticulatus in the Netherlands (de Lange et al. 2005, Nijhof et al. 2007); records of the Asian tiger mosquito in southern Germany and Switzerland; the establishment of Aedes japonicus in Belgium and France; annual epidemics of dengue fever in the Caribbean and South America; head lice have become highly resistant to insecticides; and London hotels are frequently infested with bedbugs (Ter Poorten and Prose 2005)
    Emerging pests and vector-borne diseases in Europe: Ecology and control of vector-borne diseases Volume 1
    Takken, W. ; Knols, B.G.J. - \ 2007
    Wageningen : Wageningen Academic Publishers (Ecology and control of vector-borne diseases vol. 1) - ISBN 9789086860531 - 500
    ziekten overgebracht door vectoren - plagen - infectieziekten - humane ziekten - dierziekten - ecologie - plagenbestrijding - ziektepreventie - epidemiologie - europa - globalisering - klimaatverandering - vector-borne diseases - pests - infectious diseases - human diseases - animal diseases - ecology - pest control - disease prevention - epidemiology - europe - globalization - climatic change
    This book provides examples of the most likely pests and diseases affecting man and animals in Europe, with emphasis on ecological factors favouring these diseases and methods for prevention and intervention.
    Impacts of HIV/AIDS on Labor Allocation and Crop Diversity : do Stages of the Disease Matter?
    Gebreselassie, K. ; Price, L.L. ; Wesseler, J.H.H. ; Ierland, E.C. van - \ 2006
    Wageningen : Mansholt Graduate School (Discussion paper / Mansholt Graduate School 32) - 66
    acquired immune deficiency syndrome - humaan immunodeficiëntievirussen - humane ziekten - allocatie van arbeid - werkgelegenheid buiten het landbouwbedrijf - inkomsten van buiten het landbouwbedrijf - gewasteelt - gewassen - pachtstelsel - Ethiopië - gevalsanalyse - arbeid in de landbouw - acquired immune deficiency syndrome - human immunodeficiency viruses - human diseases - labour allocation - off-farm employment - non-farm income - crop management - crops - tenure systems - Ethiopia - case studies - farm labour
    This paper deals with the impact of HIV/AIDS on labor allocation and crop diversity. The study is based on an in-depth analysis of 4 case studies in Ethiopia. A novel element in the study is the emphasis on the distinction of various stages in which the disease affects families. Results show that impact on labor allocation very much depends on the various stages of the disease and which family member (or members) is affected. Also land tenure plays an important role, because of the options of having sharecropping contracts or opportunities for off-farm labour. This has implications for the intervention strategies in the various phases of the disease, both for men and women.
    Phylogeny and taxonomy of Phaeoacremonium and its relatives
    Mostert, L. - \ 2006
    Wageningen University. Promotor(en): Pedro Crous, co-promotor(en): E.C.A. Abeln. - [S.l.] : S.n. - ISBN 9789085044604 - 249
    diaporthales - pezizomycotina - deuteromycotina - fylogenie - taxonomie - phaeohyphomycose - humane ziekten - medische mycologie - determinatietabellen - plantenziekteverwekkende schimmels - diaporthales - pezizomycotina - deuteromycotina - phylogeny - taxonomy - keys - phaeohyphomycosis - human diseases - medical mycology - plant pathogenic fungi
    Species of Phaeoacremonium are known vascular plant pathogens causing wilt and dieback of woody hosts.  The most prominent diseases in which they are involved are Petri disease and esca, which occur on grapevines and are caused by a complex of fungi, including Phaeomoniella chlamydospora and several species of Phaeoacremonium . Various Phaeoacremonium species are also opportunistic on humans, where they are known to cause phaeohyphomycosis. 

    The genus Togninia was confirmed as the teleomorph of Phaeoacremonium by means of morphology, sexual compatibility, and DNA phylogeny. Subsequently, the genus Togninia was monographed along with its Phaeoacremonium anamorphs. Ten species of Togninia and 22 species of Phaeoacremonium were treated. Several new species of Togninia were found during the course of the study, namely T. argentinensis , T. austroafricana , T. krajdenii , T.parasitica , T.rubrigena and T. viticola . New species of Phaeoacremonium includePm. alvesii, Pm. amstelodamense,Pm. argentinense ,Pm. australiense,Pm. austroafricanum, Pm. griseorubrum,Pm.krajdenii,Pm. novae-zealandiae , Pm . iranianum ,Pm. scolyti, Pm. sphinctrophorum,Pm.subulatum,Pm. tardicrescens,Pm . theobromatisandPm. venezuelense . Species were identified based on their cultural and morphological characters, supported by DNA data derived from partial sequences of the actin and β-tubulin genes. Phylogenies of the SSU and LSU rRNA genes were used to determine whether Togninia has more affinity with the Calosphaeriales or the Diaporthales . These results confirmed that Togninia had a higher affinity to the Diaporthales than the Calosphaeriales . Examination of type specimens revealed that T.cornicola , T.vasculosa , T . rhododendri, T . minima var. timidula and T.villosa , were not members of Togninia . New combinations such as Calosphaeria cornicola,Calosphaeriarhododendri , Calosphaeriatransversa , Calosphaeriatumidula,Calosphaeriavasculosa and Jattaeavillosawere therefore proposed to accommodate these species.

    The correct and rapid identification of Phaeoacremonium species is important tofacilitate the understanding of their involvementin plant as well as human disease. A rapid identification method was developed for the 22 species of Phaeoacremonium currently recognised. It involved the use of 23 species-specific primers, including 20 primers targeting the β-tubulin gene and three targeting the actin gene. These primers can be used in 14 multiplex reactions. Additionally a multiple-entry electronic key based on morphological, cultural andb-tubulin sequence data was developed to facilitate routine species identification. This database can be accessed online athttp://www.cbs.knaw.nl/phaeoacremonium.htm. With this identification tool phenotypic and sequence data can be used to identify the different Phaeoacremonium species. Separate dichotomous keys were provided for the identification of the Togninia and Phaeoacremonium species based on phenotypic characters. Additionally, keys for the identification of Phaeoacremonium -like fungi and the genera related to Togninia were also provided. 

    The mating strategy of several Togninia species was investigated with ascospores obtained from fertile perithecia produced in vitro . Togninia argentinensis and T.novae-zealandiae have homothallic mating systems, whereas T. austroafricana , T. krajdenii , T. minima , T.parasitica , T. rubrigena and T. viticola are heterothallic. The species predominantly isolated from diseased grapevines are Pm. aleophilum , Pm. parasiticum and Pm. viticola . Perithecia of two of these species, T. minima and T. viticola , have been found on grapevines in the field, indicating that these species recombine in vineyards. 

    The genetic diversity among isolates ofPa.chlamydospora on grapevines was investigated by means of Amplified Fragment Length Polymorphisms (AFLPs). Phaeomoniellachlamydospora isolates were collected from different positions on the same vine, different vines within a vineyard and different vineyards withinSouth Africa. Selected isolates from various grape producing countries, namelyAustralia,France,Italy,Iran,New Zealand,SloveniaandU.S.A.were also included. The overall low level of genetic variation confirmed asexual reproduction to be dominantin the field. Different genotypes were found among isolates ofPa.chlamydospora within the same grapevine, suggesting multiple infections from different inoculum sources. Isolates from different countries had a high percentage of similarity and clustered together, indicating the absence of genotype-geographic structure. The presence of the same genotype in different vineyards and production areas suggests that long-range dispersal through aerial inoculum or infected plant material played an important role in genotype distribution. 

    Seven species of Togninia and 15 species of Phaeoacremonium were newly described during the course of this study. The data obtained in this study, as well as the newly developed dichotomous and online polyphasic keys will enable scientists to correctly identify all the known species and also provide a reference database to which new species can be added in future. The newly reported host ranges and distributions, together with pathogenicity data, will enable scientists to identify species of possible quarantine concern.

    Campylobacter in zwemwater en mogelijke emissiebronnen
    Ruiter, H. ; Rijs, G. ; Jacobs-Reitsma, W.F. ; Leenen, I. - \ 2004
    H2O : tijdschrift voor watervoorziening en afvalwaterbehandeling 37 (2004)12. - ISSN 0166-8439 - p. 19 - 21.
    campylobacter - zwemmen - waterverontreiniging - humane ziekten - waterkwaliteit - besmetting - oppervlaktewater - afvoerwater - volksgezondheid - campylobacter - swimming - water pollution - human diseases - water quality - contamination - surface water - effluents - public health
    Campylobacter vormt samen met Salmonella en Shigella één van de belangrijkste bacteriële ziekteverwekkers van het maagdarmkanaal bij de mens. De bacterie Campylobacter komt voor bij eenden, meeuwen, kippen en kalkoenen, maar is ook aanwezig in koeien, varkens en schapen. Al deze dieren zijn drager, maar worden er zelf niet ziek van. Infecties met Campylobacter leiden in Nederland jaarlijks tot circa honderdduizend gevallen van maagdarmstoornissen en enkele duizenden gevallen van reactieve artritis (spierontsteking). De infectieuze dosis is laag en de besmetting vindt doorgaans plaats via de fecaal-orale route. Uit een inventariserend onderzoek blijkt dat naast de algemeen bekende besmettingsroute via voedsel (voornamelijk pluimveevlees) ook verontreinigd zwemwater een besmettingsbron kan vormen
    Risk-analysis of human pathogen spread in the vegetable industry: a comparison between organic and conventional production chains
    Franz, E. ; Bruggen, A.H.C. van; Semenov, A.M. - \ 2004
    In: Bayesian Statistics and Quality Modelling in the Agro-Food Production Chain / van Boekel, M.A.J.S., Stein, A., van Bruggen, A.H.C., Dordrecht : Kluwer Academic Publishers - ISBN 9781402019166 - p. 81 - 94.
    bayesiaanse theorie - ziekten overgebracht door voedsel - risicoschatting - pathogenen - humane ziekten - voedselbesmetting - groenten - agro-industriële ketens - bayesian theory - foodborne diseases - risk assessment - pathogens - human diseases - food contamination - vegetables - agro-industrial chains
    An overview is given of recent problems with food-borne enteric human pathogens originating from contaminated agricultural animals. The need for risk analysis is indicated, and the generally accepted procedure for risk assessment is outlined. Two main approaches to probability and risk calculations, namely the “frequentist” and Bayesian approaches, are described. Examples are given of microbial risk assessments in vegetable production that were mainly based on “frequentist” probability assessments. Finally, a Dutch-Russian collaborative project on risk assessment of enteric pathogens in organic and conventional vegetable production chains is outlined, and preliminary data are presented. We conclude that a Bayesian approach, using prior probabilities, is the most appropriate instrument for risk assessment of human-pathogen spread in the vegetable industry
    Irrigation ecology of schistosomiasis : environmental control options in Morocco
    Boelee, E. - \ 2000
    Agricultural University. Promotor(en): R.A. Feddes; B.M.A.J. Gryseels; F.P. Huibers. - S.l. : S.n. - ISBN 9789058081438 - 199
    irrigatie - schistosomiase - schistosoma - humane ziekten - milieubeheersing - irrigatiesystemen - ziekteoverdracht - ecologie - marokko - irrigation - schistosomiasis - schistosoma - human diseases - environmental control - irrigation systems - disease transmission - ecology - morocco

    The concept of irrigation ecology is introduced to study the transmission and the control of urinary schistosomiasis in Moroccan irrigation systems. By distinguishing a biological, a human and an irrigation environment, crucial interactions are identified in the overlap of these three environments. In the semi-arid Haouz plain in Central Morocco, schistosomiasis was introduced after the construction of the Tessaout Amont irrigation system in the early 1970s. The typical design of this canal irrigation system, with elevated semi-circular conduits as secondary and tertiary canals, is based on upstream control and the water is distributed in rotation. Inverted siphons, consisting of two square boxes connected by an underground pipe, have been constructed to convey the water under roads or tracks. The boxes contain stagnant water and provide excellent breeding sites for Bulinus truncatus , the intermediate snail host of schistosomiasis.

    A cross-sectional survey showed that especially inverted siphons on tertiary canals harbour high densities of B.truncatus . A length profile study along one secondary canal and four of its tertiaries showed that conditions near the tail end of canals, especially in the downstream siphon boxes, are most favourable to the intermediate snail host. The transmission of schistosomiasis in Tessaout Amont is concentrated at these siphons as, in the absence of other sources, water from the boxes is used for all kinds of agricultural and domestic purposes, inducing frequent water contact.

    Three environmental control options have been studied. Regular emptying and cleaning of siphon boxes had a limited effect on densities of Bulinus truncatus snails and eggs. Creating a dark environment by covering siphon boxes with iron plates proved to be much more effective in reducing B.truncatus populations. Some of the covers were equipped with moveable lids to leave the water accessible to the villagers. The third control option concerned measures to increase the water flow velocity in siphons. Combining flow velocities with the duration of the flow results in a mean annual flow velocity. According to literature, above a critical value of 0.042 m/s, no B.truncatus snails are to be found in siphon boxes. In siphons with a lower mean annual flow velocity, this critical value can be obtained by reducing the inner dimensions of the siphon boxes, thus increasing the water flow velocity. However, in experiments with such smaller siphon boxes, the siphons were quickly repopulated with B.truncatus . Better results might be achieved by redefining the critical value. However, the small diameter siphons generate higher energy losses. Consequently, such siphons can only be applied in a layout where access to the fields is guaranteed through simple bridges over the drains, which significantly reduces the number of required siphons.

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