Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Between odours and overeating : behavioural and neurobiological mechanisms of olfactory food-cue reactivity
    Zoon, Harriët F.A. - \ 2017
    Wageningen University. Promotor(en): Cees de Graaf, co-promotor(en): Sanne Boesveldt. - Wageningen : Wageningen University - ISBN 9789463431675 - 178
    geurstoffen - overeten - neurobiologie - voedingsgedrag - reukstimulatie - obesitas - eetlust - overgewicht - buik bypass - verzadigdheid - odours - overeating - neurobiology - feeding behaviour - olfactory stimulation - obesity - appetite - overweight - gastric bypass - satiety

    The obesogenic environment we live in is characterized by an abundance of available foods and food cues that tempt us to eat. Throughout our lives we learn to associate these food cues (odours, pictures) with physiological consequences of food consumption. The sense of smell is suggested to be very important for determining food quality, guiding us away from spoilt food and towards rewarding foods. Increased sensitivity to environmental cues of rewarding food, decreased sensitivity to physiological cues of hunger and a decreased ability to control impulses are thought to contribute to overeating and obesity. With the research in this thesis we aimed to elucidate the role of odours in (over)eating, to better understand how sensory food cues and hunger feelings are involved in determining our eating pattern.

    We assessed the appetizing effects of exposure to odours signalling food with a certain taste (sweet/savoury) and energy density (high/low). Our findings show that smelling a food odour increases appetite for foods that are similar to the odour, both in terms of taste and energy density. These appetizing effects were present when participants were hungry but also when they had just eaten, indicating a possible role in overeating.

    Further, consumption of a high-energy food with a certain taste (sweet/savoury) led to a decrease in liking and wanting of foods with a similar taste and energy density. Next to this, we observed more pronounced changes in early neural processing of pictures of high-energy/sweet food after consumption of a high-energy/sweet meal.

    Food preferences and -intake after ambient exposure to odours signalling high-energy food, low-energy food and non-food were not different. Odours did not affect these measures of eating behaviour differently in a hungry or satiated state and in normal-weight or overweight participants.

    In a group of patients who underwent Roux-en-Y Gastric Bypass weight-loss surgery, we found a shift in food preferences away from high-fat/high-sugar and towards low-fat/low-sugar foods and altered activation in the frontoparietal neural network during (food) cue processing. After compared to before surgery we also found altered prefrontal neural responses when patients inhibited their responses to pictures of high-energy food. These results suggest that RYGB leads to changes in cognitive control of attention and increased neural inhibitory control over behavioural responses.

    In conclusion, odours have a specific appetizing function in the anticipatory phase of eating. They are important in determining the taste quality and energy-density and may be involved in the selection of foods for macronutrient regulation. Orthonasal odours should be used to guide food selection towards a healthier eating pattern.

    Nutritional interventions to preserve skeletal muscle mass
    Backx, Evelien M.P. - \ 2016
    Wageningen University. Promotor(en): Lisette de Groot; L.J.C. van Loon. - Wageningen : Wageningen University - ISBN 9789462579149 - 158
    musculoskeletal system - nutritional intervention - skeletal muscle - vitamin d - creatine - leucine - nandrolone - protein intake - young adults - elderly - overweight - athletes - preservation - skeletspierstelsel - maatregel op voedingsgebied - skeletspier - vitamine d - creatine - leucine - nandrolon - eiwitinname - jongvolwassenen - ouderen - overgewicht - atleten - behoud

    Muscle mass is the main predictor for muscle strength and physical function. The amount of muscle mass can decline rapidly during periods of reduced physical activity or during periods of energy intake restriction. For athletes, it is important to maintain muscle mass, since the loss of muscle is associated with decreased muscle strength, decreased physical performance and a longer recovery period. In the older and more clinically compromised populations, the consequences of muscle loss can substantially impact metabolic health, physical functioning, quality of life and mortality rates. In this thesis, the effects of different nutritional interventions on the preservation of muscle mass are being evaluated.

    Vitamin D deficiency (serum 25-hydroxyvitamin D or 25(OH)D) has been associated with increased muscle loss and reduced muscle strength. In chapter 2, we identified seasonal changes in 25(OH)D concentration in elite athletes. We observed that 25(OH)D concentrations were highest at the end of summer (113±26 nmol/L), and lowest at the end of winter (78±30 nmol/L). Athletes that had a sufficient 25(OH)D concentration (>75 nmol/L) at the start of the study, still had a high risk (20%) of being deficient (<50 nmol/L) in late winter. Thus, a sufficient 25(OH)D concentration in summer does not guarantee a sufficient status in winter. In chapter 3, we assessed 25(OH)D concentrations in 128 highly-trained athletes and found that 70% had a deficient or insufficient 25(OH)D concentration at the end of the winter season. Supplementation with 2200 IU/d vitamin D resulted in a sufficient 25(OH)D concentration in 80% of the athletes after 12 months and was therefore a better dosage to improve 25(OH)D concentration than 400 or 1100 IU/d.

    In the following chapters, we assessed the effects of creatine supplementation (chapter 4), leucine supplementation (chapter 5) and nandrolone administration (chapter 6) on the preservation of muscle mass during a short period of muscle disuse. For all of these compounds there is prior evidence for their efficacy in augmenting muscle mass and strength gains in combination with resistance-type exercise training and all have been suggested to attenuate the loss of muscle mass during a period of muscle disuse. During 7 days of single-leg immobilization, muscle mass decreased by ~6% and muscle strength decreased by ~8%. Surprisingly, none of the tested compounds attenuated the loss of muscle mass during 7 days of single-leg immobilization in healthy, young men.

    In chapter 7, we performed a fully controlled dietary intervention to assess the impact of a high protein intake on the preservation of lean body mass during 12 weeks of energy intake restriction. Sixty-one overweight and obese men and women were randomly assigned to either a high protein diet (1.7 g/kg/d) or a normal protein diet (0.9 g/kg/d) during 12 weeks of 25% energy intake restriction. During the dietary intervention, subjects lost 9±3 kg body weight with a concomitant 2±2 kg decline in lean body mass with no differences between the two intervention groups. Thus, increasing protein intake above habitual intake levels (0.9 g/kg/d) did not preserve lean body mass during a period of energy intake restriction.

    Finally, in chapter 8 we reflected on the main findings described in this thesis. In this chapter, we point out that the populations studied were all healthy and well-nourished. We conclude that in these populations, additional creatine, leucine and protein beyond habitual intakes did not preserve muscle mass. Older and/or malnourished individuals might be more responsive to these nutritional interventions. Future research could also focus on the combined effects of two or more nutritional compounds during disuse that are known to affect different mechanisms. Moreover, we speculate that the tested nutritional compounds could be effective in accelerating the regain of muscle mass and strength after a period of muscle loss. However, it should be noted that muscle loss during disuse occurs at a rate that is several-fold greater than muscle (re)gain during resistance type exercise training. Therefore, it is imperative that we continue our endeavors to identify nutritional or pharmaceutical compounds or exercise mimetics that may help to prevent or attenuate disuse atrophy.

    Hoe kun je te dik en toch gezond zijn?
    Witkamp, R.F. - \ 2015
    Universiteit van Nederland
    overgewicht - lichaamsgewicht - quetelet index - obesitas - gezondheid - volksgezondheid - buikvet - lichaamsvet - fysiologie - overweight - body weight - body mass index - obesity - health - public health - abdominal fat - body fat - physiology
    Je kijkt naar beneden en ziet dat er zich in de loop der jaren wat vet is gaan ophopen rondom je middel. Waarom is het gevaarlijk om juist daar teveel vet te hebben? Renger Witkamp (Wageningen UR) legt uit hoe het nu precies zit met de gevaren van die extra kilootjes en of het per definitie ongezond is om wat dikker te zijn.
    Overweight and obesity in primary-school children: a surveillance system for policy-making in Europe from 2007 onwards
    Wijnhoven, T.M.A. - \ 2015
    Wageningen University. Promotor(en): Pieter van 't Veer, co-promotor(en): Joop van Raaij. - Wageningen - ISBN 9789462574656 - 265
    overgewicht - obesitas - quetelet index - lichaamsgewicht - schoolkinderen - kinderen - kwantitatieve analyse - who - gezondheid van kinderen - risicoschatting - kindervoeding - lichamelijke activiteit - kleding - overweight - obesity - body mass index - body weight - school children - children - quantitative analysis - who - child health - risk assessment - child nutrition - physical activity - clothing

    Trudy M.A. Wijnhoven

    Overweight and obesity in primary-school children: a surveillance system for policy-making in Europe from 2007 onwards.

    Background

    As a follow-up to the European Ministerial Conference on Counteracting Obesity convened in 2006 in Turkey, the European Childhood Obesity Surveillance Initiative (COSI) was launched by the Regional Office for Europe of the World Health Organization (WHO). COSI, a collaboration between WHO and interested Member States, aims to monitor the magnitude of overweight and obesity among primary-school children in European countries, to allow intercountry comparisons and to identify regional differences for informed policy-making. It collects at regular intervals data on weight and height of primary-school children and on their nutrition and physical activity behaviours, as well as on school environmental characteristics supportive to healthy nutrition and physical activity.

    Methods

    The research described in this PhD thesis is based on the data collected in the first two COSI rounds by 12 European countries in school year 2007/2008 and by 13 European countries in school year 2009/2010. Nationally representative samples of children aged 6–9 years were drawn, whereby a majority of the countries applied a two-stage school-based cluster sampling approach.

    A total of 168 832 children in school year 2007/2008 and 224 920 children in school year 2009/2010 were included in the anthropometric intercountry data analyses. Children's weight and height were measured by trained examiners using standardized procedures. Participating countries were allowed to adhere to their local legal requirements by specified deviations from standardized procedures, such as in types of clothing worn by the children during weight and height measurements. For each country, the prevalence of overweight and obesity, as well as mean Z-scores of anthropometric indices of height, weight and body mass index (BMI) were computed.

    The characteristics included in the analyses on the school environment referred to the frequency of physical education lessons, the availability of school playgrounds, the possibility to obtain food items and beverages on the school premises, and the organization of school initiatives to promote a healthy lifestyle. The school form was usually completed by the school principal or the teachers involved with the sampled classes. Data from 1831 schools in school year 2007/2008 and from 2045 schools in school year 2009/2010 were used. For each school, a school nutrition environment score (range: 0–1) was determined whereby higher scores correspond to higher support for a healthy school nutrition environment and the mean of the children's BMI-for-age Z-scores calculated.

    Five countries in school year 2007/2008 provided children's data on 13 health-risk behaviours related to breakfast and food consumption frequency, physical activity, screen time and sleep duration (n = 15 643). These data were reported by the caregivers alone or jointly with their child. For each country, the prevalence of the risk behaviours was estimated, and associations between them and overweight and obesity examined by multilevel logistic regression analyses.

    Results

    In both school years, a wide range in overweight and obesity prevalence estimates was found that differed significantly by country, as well as by European region. In all countries, the percentage of overweight children was about 20% or more (range: 18–57%), and the percentage of obese children was 5% or more (range: 5–31%). The findings suggest the presence of a north–south gradient with the highest overweight and obesity prevalence estimates found in southern European countries. Furthermore, changes in mean BMI-for-age Z-scores (range: from –0.21 to +0.14) and prevalence of overweight (range: from –9.0% to +6.2%) from school year 2007/2008 to school year 2009/2010 varied significantly among countries, whereas a period of two years is considered too short to identify these developments. The clothes-adjusted overweight prevalence estimates were lower by as much as 12% than the unadjusted estimates. Monthly BMI-for-age Z-score values within countries did not show systematic seasonal effects.

    Large between-country differences were observed in both school years in the availability of food items or beverages on the school premises (e.g., fresh fruit could be obtained in 12–95% of schools) and in the organization of initiatives to promote a healthy lifestyle in the selected classes (range: 42–97%). The provision of physical education lessons and the availability of school playgrounds were more uniformly present across the countries (range: 76–100%). A large variation was also seen in school nutrition environment scores (range: 0.30–0.93) whereby countries with a low score (< 0.70) graded less than three out of five characteristics as supportive. High-score countries showed more often than low-score countries a combined absence of cold drinks containing sugar, sweet snacks and salted snacks on the school premises.

    The prevalence of all 13 health-risk behaviours differed significantly across countries. For instance, the percentage of children who ate ‘foods like candy bars or chocolate’ > 3 days/week ranged from 2.2% to 63.4%; this figure ranged from 1.1% to 46.5% for those who ate ‘foods like potato chips (crisps), corn chips, popcorn or peanuts’ > 3 days/week. The range for children who did not have breakfast every day was between 4.4% and 32.5%, and from 4.8% to 35.0% for those who did not play outside ≥ 1 hour/day. Not having breakfast daily and spending screen time ≥ 2 hours/day were clearly positively associated with obesity. The same was true for eating ‘foods like pizza, French fries, hamburgers, sausages or meat pies’ > 3 days/week and playing outside < 1 hour/day. While a combination of multiple less favourable physical activity behaviours was clearly positively associated with obesity, a combination of the presence of multiple unhealthy eating behaviours did not lead to higher odds of obesity.

    Conclusions

    The results found in both COSI school years show that overweight and obesity among 6–9-year-old children are a serious public health concern, especially in southern European countries, and show the need for accelerated efforts to prevent excess body weight early in life by all participating countries. It was possible to detect relevant changes within a period of two years but to identify clear trends within countries, a longer time interval is necessary. The data on the school nutrition environment and the children's health-risk behaviours may assist policy-makers in monitoring their national policies targeting school settings and childhood obesity. In particular, promoting physical activity-related and discouraging sedentary behaviours among schoolchildren in the context of obesity preventive interventions seem to be essential.

    Aantafel! helpt tegen kinderobesitas
    Ramaker, R. ; Hoek, E. van - \ 2015
    Resource: nieuwssite voor studenten en medewerkers van Wageningen UR (2015). - ISSN 1389-7756
    overgewicht - obesitas - kinderen - gezondheid van kinderen - voeding en gezondheid - programmaeffectiviteit - gezondheidsbevordering - gezondheidsprogramma's - overweight - obesity - children - child health - nutrition and health - program effectiveness - health promotion - health programs
    Steeds vaker komt overgewicht voor bij kinderen. Doelgroepen bereiken is grote uitdaging.
    The double burden of malnutrition: obesity and iron deficiency
    Cepeda López, A.C. - \ 2015
    Wageningen University. Promotor(en): Michael Zimmermann, co-promotor(en): Alida Melse-Boonstra; I. Herter Aeberli; S. Osendarp. - Wageningen : Wageningen University - ISBN 9789462574465 - 158
    obesitas - overgewicht - ijzergebrekanemie - gebreksziekten - slechte voeding - ontsteking - ijzerabsorptie - ascorbinezuren - ascorbinezuur - vrouwen - kinderen - kindervoeding - bloedvolume - mens - obesity - overweight - iron deficiency anaemia - deficiency diseases - malnutrition - inflammation - iron absorption - ascorbic acids - ascorbic acid - women - children - child nutrition - blood volume - man

    Background: The world faces a “double burden” of malnutrition; this is true especially in transition countries like Mexico. The co-existence of obesity and iron deficiency (ID) within a person has been clearly demonstrated in several studies but the mechanisms linking them remain largely unknown.

    Objectives: To investigate possible mechanisms that link obesity and iron status through the following specific objectives: a) reviewing the existing literature; b) investigating the coexistence of obesity and iron deficiency at the national level in Mexico; c) assessing and comparing iron absorption and blood volume (BV) in healthy, non-anemic women from different body mass index (BMI) categories, and evaluating if ascorbic acid improves iron absorption in overweight (OW) and obese (OB) women; d) evaluating if differences in BV explains reduced iron status in OW/OB women; and e) evaluating whether fat loss in obese subjects decreases inflammation and serum hepcidin and thereby improves iron absorption.

    Methods: a) A literature review was conducted using Google Scholar and PubMed search engines; b) data from the 1999 Mexican Nutrition Survey, which included 1174 children (aged 5–12 y) and 621 nonpregnant women (aged 18–50 y), was used to assess the relationship between BMI, dietary iron, and dietary factors affecting iron bioavailability, iron status, and inflammation; c & d) healthy, non-anemic Swiss women (n=62) (BMI 18.5-39.9 kg/m2) consumed a stable-isotope labelled wheat-based test meal, without (-AA) and with (+AA) 31.4 mg ascorbic acid. We measured iron absorption, body composition by dual energy X-ray absorptiometry (DXA), blood volume by carbon monoxide (CO)-rebreathing method, iron status, inflammation and serum hepcidin; e) We performed a 6-month, prospective study in OB (BMI, ≥35<45 kg/m2) adults from Mexico (n=..), who had recently undergone laparoscopic sleeve-gastrectomy (LSG). At 2 months and 8 months post-LSG, subjects consumed a test drink with 6mg 57Fe as ferrous sulfate and were intravenously infused with 100 μg 58Fe as iron citrate and we measured body composition by DXA, iron status, hepcidin and inflammation.

    Results: a) Obesity-related subclinical inflammation and its effects on hepcidin levels seem to be the most plausible explanation for the link between ID and obesity; b) the risk of iron deficiency in OB women and children was 2-4 times that of normal-weight individuals at similar dietary iron intakes. In addition, we found that C-reactive protein but not iron intake was a strong negative predictor of iron status, independently of BMI (P < 0.05); c) dietary iron absorption was lower in OW/OB versus normal weight subjects (Geometric mean (95%CI): 12.9 (9.7, 16.9)%) vs 19.0 (15.2, 23.5)%, P=0.049). Moreover, the enhancing effect of ascorbic acid on iron absorption in overweight/obese (28%) was only half that in normal weight women (56%); d) OW/OB women presented higher absolute blood volume and lower serum iron compared to the normal weight group. BV (r2=0.22, β=-0.29, P=0.02) was a negative predictor for serum iron when adjusted for body iron stores. We developed an equation to calculate BV in OW and OB women considering weight, height and lean body mass; e) Fat loss lead to a reduction of inflammation (Interleukin-6) and hepcidin concentrations. In iron-deficient subjects (n=17), iron absorption significantly increased after fat loss (Geometric mean (95%CI): 9.7% (6.5-14.6) to 12.4% (7.7-20.1) (P=0.03), while in iron sufficient subjects (n=21), it did not change (Geometric mean (95%CI): 5.9% (4.0-8.6) and 5.6% (3.9-8.2)) (P=0.81)).

    Conclusion: Increased hepcidin concentrations, along with subclinical inflammation, limits dietary iron absorption in subjects with excessive body fat, especially in iron deficient individuals. Due to a dilutional effect of blood volume, ‘true’ hypoferremia might be overestimated in populations with a high prevalence of obesity when using serum iron as an indicator. OW/OB individuals may require: higher dietary iron intake combined with iron absorption enhancers to keep their iron status in balance; and a reduction of the obesity-related inflammatory process in order to ensure adequate iron absorption.

    Young children and obesity : development and evaluation of familiy-oriented treatment
    Hoek, E. van - \ 2015
    Wageningen University. Promotor(en): Edith Feskens, co-promotor(en): A.J. Janse; Laura Bouwman. - Wageningen : Wageningen University - ISBN 9789462574540 - 182
    obesitas - overgewicht - kinderen - peuters en kleuters - pediatrie - behandeling - kinderziekten - medische behandeling - lichaamssamenstelling - kwaliteit van het leven - vetweefsel - hart- en vaatziekten - kwantitatieve methoden - voeding en gezondheid - obesity - overweight - children - preschool children - paediatrics - treatment - childhood diseases - medical treatment - body composition - quality of life - adipose tissue - cardiovascular diseases - quantitative methods - nutrition and health

    Thesis: Young Children and Obesity – Development and Evaluation of Family-oriented Treatment, Esther van Hoek

    Introduction

    The prevalence of childhood obesity has increased rapidly during the last decades. Childhood obesity is a multisystem disease with serious consequences such as hypertension, dyslipidemia, chronic inflammation, endothelial dysfunction and hyperinsulinemia. In addition, obese children have a decreased health-related quality of life (HRQoL).

    The age interval of 3 to 7 years is a critical growth period. Fast increase of weight in this period is associated with obesity later in life. Furthermore, starting treatment at younger age is associated with a larger reduction in overweight. At the start of this project in 2009, there was no evaluated treatment program available for young obese children (defined as 3 to 8 years).

    The risk of cardiovascular diseases and type 2 diabetes (i.e. cardiometabolic risk) can be assessed by measuring conventional risk factors (for example blood pressure). Other markers, such as pro-inflammatory markers, are part of the cardiometabolic risk profile. Epicardial adipose tissue is a metabolically active cardiac fat depot. In obese adults, the epicardial adipose tissue thickness (EATT) is increased, this is correlated to atherosclerosis. It is unknown whether young overweight children have already increased EATT.

    The aim of this thesis is to develop, implement and evaluate a treatment program for obese young children. Furthermore, it aims to assess whether EATT is increased in obese young children and is correlated with the cardiometabolic risk profile, and with treatment.

    Methods

    The treatment program for obese young children is developed based on a review of the clinical guidelines, a literature review (including a systematic review with meta-analysis and an extended literature review) and target group interviews. The findings were integrated with professional judgement. To evaluate the resulting program called AanTafel!, a pilot study was performed (n=7 children), including a process evaluation based on parental interviews and questionnaires with the therapists. The effectiveness of AanTafel! was evaluated with a pre-post-test design including 40 children with a median BMI z-score of 3.4 (standard deviation 1.0) in secondary care. The BMI-z-score was the main outcome measure. Secondary outcome measures were components of the metabolic syndrome, markers of cardiometabolic risk, and HRQoL. Outcome measures were assessed at baseline and at the end of treatment (1 year). The BMI z-score was also evaluated 3 years after baseline in the first 23 children who finished treatment. EATT was measured by echocardiography in 25 obese, 8 overweight, and 15 normal weight young children. In the obese and overweight children the EATT, as well as cardiometabolic risk factors, and the markers adiponectin and high sensitive CRP (hsCRP) were measured at baseline and after treatment.

    Results

    Meta-analysis showed that multicomponent treatment programs of moderate or high intensity (> 26 hours) were the most effective and resulted in a decrease of BMI z-score of 0.5. During the development of the treatment program, the gaps in evidence in clinical guidelines for childhood obesity treatment were overcome by insights from an additional literature review, target group interviews and professional judgement. The resulting treatment program AanTafel! has the following key characteristics: multicomponent, multidisciplinary, family-based with focus on parents, age-specific, tailored to individual children and families, a duration of one year and a combination of individual and group sessions and a web-based learning module. The pilot study showed that to improve parental involvement, peer support, family tailoring, and highly participative elements (such as self-monitoring) are important. The treatment program AanTafel! resulted in a change of mean BMI z-score of -0.5 directly after finishing treatment. This clinical relevant result persisted 2 years after baseline. Furthermore, a significant increase in HDL cholesterol and a reduction in the number of components of metabolic syndrome were found. Regarding markers of cardiometabolic risk, an overall significant decrease was seen in IL18, e-selectin, and sICAM. The HRQoL showed a non-significant improvement in most domains, with a clinically relevant improvement in the physical summary score. EATT was higher in overweight and obese young children compared to their normal weight peers. EATT was inversely correlated with adiponectin, but correlations with other cardiometabolic risk factors were not statistically significant. EATT did not change during treatment (n=17).

    Conclusion

    During the development process of an obesity treatment program, it was important to add the views of the target group and therapists to the evidence from clinical guidelines and literature review. The resulting treatment program AanTafel! is effective with a clinically relevant decrease of BMI z-score, an improvement of cardiometabolic risk profile, and a clinically relevant increase in the physical summary score of HRQoL. EATT is increased in obese young children; this is inversely correlated with adiponectin.

    Replacing Non-Active Video Gaming by Active Video Gaming to Prevent Excessive Weight Gain in Adolescents
    Simons, M. ; Brug, J. ; Chinapaw, M.J.M. ; Boer, M. de; Seidell, J. ; Vet, E. de - \ 2015
    PLoS ONE 10 (2015)7. - ISSN 1932-6203 - 21 p.
    randomized controlled-trial - physical-activity levels - sedentary behavior - health indicators - childhood obesity - screen time - children - games - overweight - questionnaire
    Objective - The aim of the current study was to evaluate the effects of and adherence to an active video game promotion intervention on anthropometrics, sedentary screen time and consumption of sugar-sweetened beverages and snacks among non-active video gaming adolescents who primarily were of healthy weight. Methods - We assigned 270 gaming (i.e. =2 hours/week non-active video game time) adolescents randomly to an intervention group (n = 140) (receiving active video games and encouragement to play) or a waiting-list control group (n = 130). BMI-SDS (SDS = adjusted for mean standard deviation score), waist circumference-SDS, hip circumference and sum of skinfolds were measured at baseline, at four and ten months follow-up (primary outcomes). Sedentary screen time, physical activity, consumption of sugar-sweetened beverages and snacks, and process measures (not at baseline) were assessed with self-reports at baseline, one, four and ten months follow-up. Multi-level-intention to treat-regression analyses were conducted. Results - The control group decreased significantly more than the intervention group on BMI-SDS (ß = 0.074, 95%CI: 0.008;0.14), and sum of skinfolds (ß = 3.22, 95%CI: 0.27;6.17) (overall effects). The intervention group had a significantly higher decrease in self-reported non-active video game time (ß = -1.76, 95%CI: -3.20;-0.32) and total sedentary screen time (Exp (ß = 0.81, 95%CI: 0.74;0.88) than the control group (overall effects). The process evaluation showed that 14% of the adolescents played the Move video games every week =1 hour/week during the whole intervention period. Conclusions - The active video game intervention did not result in lower values on anthropometrics in a group of ‘excessive’ non-active video gamers (mean ~ 14 hours/week) who primarily were of healthy weight compared to a control group throughout a ten-month-period. Even some effects in the unexpected direction were found, with the control group showing lower BMI-SDS and skin folds than the intervention group. The intervention did result in less self-reported sedentary screen time, although these results are likely biased by social desirability.
    Tafel van Louise Fresco : tentoonstelling Foodtopia, Boerhaave Museum
    Fresco, L.O. - \ 2015
    Wageningen : Wageningen UR
    voedingsmiddelen - algen - aardappelen - appels - etiketteren van voedingsmiddelen - insecten als voedsel - overgewicht - robots - brood - dierenwelzijn - vis - voedselproductie - foods - algae - potatoes - apples - nutrition labeling - insects as food - overweight - robots - bread - animal welfare - fish - food production
    Hoe ziet ons eten er in de toekomst uit? En waar halen we het vandaan? Louise O. Fresco, voorzitter van de Raad van Bestuur van Wageningen UR, is gastconservator van de tentoonstelling FOODTOPIA in museum Boerhaave. Deze filmpjes zijn onderdeel van de tentoonstelling en geeft een kijkje in de toekomst van ons voedsel. Onderwerpen zijn: algen, aardappel, de appel, etiketten, insecten, overgewicht, respect, robots, brood, dierenwelzijn en vis.
    Navigating the obesogenic environment: How psychological sensitivity to the food environment and self-regulatory competence are associated with adolescent unhealthy snacking
    Stok, F.M. ; Vet, E. de; Wardle, J. ; Chu, M.T. ; Wit, J.B.F. ; Ridder, D.T.D. de - \ 2015
    Eating Behaviors 17 (2015). - ISSN 1471-0153 - p. 19 - 22.
    health consequences - obesity - gratification - strategies - overweight - worldwide - autonomy - children - adults - scale
    Purpose: Living in an obesogenic environment may not affect all adolescents to the same extent, depending on their psychological sensitivity to the food environment and their self-regulatory competence. The purpose of the current study was to examine associations of these two factors with unhealthy snacking among adolescents. We also investigated whether self-regulatory competence could attenuate the negative effects of being sensitive to the food environment. Methods: A survey was completed by 11,392 European adolescents (10–17 years old). The survey measured psychological sensitivity to the food environment, self-regulatory competence and self-reported unhealthy snack intake. Results: Higher food environment sensitivity and lower self-regulatory competence were associated with more unhealthy snacking. The two factors also interacted, with self-regulatory competence attenuating the influence of high food environment sensitivity. Discussion: Adolescentswho are sensitive to the food environment reported higher unhealthy snack intake.More frequent use of self-regulation strategies on the other hand was associated with lower unhealthy snack intake. Moreover, self-regulatory competence was found to moderate the influence of psychological sensitivity to the food environment on unhealthy snacking, although the effect size was small. Fostering adolescents' self-regulatory competence can help enable them to better navigate the obesogenic environment.
    Vechten tegen verleiding
    Rademaker, R. ; Vet, E.W.M.L. de - \ 2015
    Resource: nieuwssite voor studenten en medewerkers van Wageningen UR 9 (2015)17. - ISSN 1389-7756 - p. 10 - 10.
    voeding en gezondheid - voedselconsumptie - obesitas - overgewicht - gezondheidsbevordering - snacks - nutrition and health - food consumption - obesity - overweight - health promotion - snacks
    Onze omgeving maakt dik. Porties worden groter, eten is overal en beweging wordt ontmoedigd. Emely de Vet, universitair hoofddocent bij Strategische communicatie, zoekt daarom naar strategieën om de lokroep van brownies en zakken chips te weerstaan.
    Breakfast benefits for children and adolescents
    Vingerhoeds, M.H. - \ 2015
    Wageningen : Wageningen UR (Report / Wageningen UR Food & Biobased Research 1564) - ISBN 9789462575158 - 26
    kinderen - kindervoedering - adolescenten - voedingsgewoonten - ontbijt - gezondheid - voeding en gezondheid - voedselconsumptie - overgewicht - children - child feeding - adolescents - feeding habits - breakfast - health - nutrition and health - food consumption - overweight
    This literature review aimed to give some insight in the benefits of breakfast for children and adolescents, with a focus on overweight, food intake and cognition. In addition, we explored the magnitude of skipping breakfast in the Netherlands and factors associated with this behaviour.
    It's my party and I eat if I want to. Reasons for unhealthy snacking
    Verhoeven, A.A.C. ; Adriaanse, M.A. ; Vet, E. de; Fennis, B.M. ; Ridder, D.T.D. de - \ 2015
    Appetite 84 (2015). - ISSN 0195-6663 - p. 20 - 27.
    implementation intentions - self-regulation - food-intake - behavior - questionnaire - consequences - adolescents - overweight - habit - plans
    Investigating the reasons that people give for unhealthy snacking behavior is important for developing effective health interventions. Little research, however, has identified reasons that apply to a large audience and most studies do not integrate multiple factors, precluding any conclusions regarding their relative importance. The present study explored reasons for unhealthy snacking among a representative community sample. Participants (N¿=¿1544) filled out the newly developed Reasons to Snack inventory assessing an elaborate range of motives at baseline and 1-month follow-up. Exploratory and replication factor analyses identified six categories: opportunity induced eating, coping with negative emotions, enjoying a special occasion, rewarding oneself, social pressure, and gaining energy. The highest mean scores were obtained for enjoying a special occasion and opportunity induced eating. Regression analyses with participant characteristics as independent variables and each category of reasons as dependent variables showed differences for age. For all reasons except to enjoy a special occasion, younger people reported a higher score. Women indicated a higher score than men on coping with negative emotions, enjoying a special occasion and gaining energy. People who diet to a stronger extent reported a higher score for snacking because of social pressure, to reward oneself and to cope with negative emotions, with the latter also being related to a higher BMI. Finally, a higher education was associated with enjoying a special occasion. Future health interventions could allocate more attention to diminishing unhealthy snacking with regard to the six identified categories, specifically focusing on enjoying a special occasion and opportunity induced eating.
    Communicating eating-related rules. Suggestions are more effective than restrictions
    Stok, F.M. ; Vet, E. de; Wit, J.B.F. ; Renner, B. ; Ridder, D.T.D. de - \ 2015
    Appetite 86 (2015). - ISSN 0195-6663 - p. 45 - 53.
    psychological reactance - self-determination - ego depletion - food - consumption - behavior - obesity - fruit - temptation - overweight
    Background: A common social influence technique for curbing unhealthy eating behavior is to communicate eating-related rules (e.g. ‘you should not eat unhealthy food’). Previous research has shown that such restrictive rules sometimes backfire and actually increase unhealthy consumption. In the current studies, we aimed to investigate if a milder form of social influence, a suggested rule, is more successful in curbing intake of unhealthy food. We also investigated how both types of rules affected psychological reactance. Method: Students (N¿=¿88 in Study 1, N¿=¿51 in Study 2) completed a creativity task while a bowl of M&M's was within reach. Consumption was either explicitly forbidden (restrictive rule) or mildly discouraged (suggested rule). In the control condition, consumption was either explicitly allowed (Study 1) or M&M's were not provided (Study 2). Measures of reactance were assessed after the creativity task. Subsequently, a taste test was administered where all participants were allowed to consume M&M's. Results: Across both studies, consumption during the creativity task did not differ between the restrictive- and suggested-rule-conditions, indicating that both are equally successful in preventing initial consumption. Restrictive-rule-condition participants reported higher reactance and consumed more in the free-eating taste-test phase than suggested-rule-condition participants and control-group participants, indicating a negative after-effect of restriction. Discussion: Results show that there are more and less effective ways to communicate eating-related rules. A restrictive rule, as compared to a suggested rule, induced psychological reactance and led to greater unhealthy consumption when participants were allowed to eat freely. It is important to pay attention to the way in which eating-related rules are communicated.
    The proof is in the eating: subjective peer norms are associated with adolescents’ eating behaviour
    Stok, F.M. ; Vet, E. de; Wit, J.B.F. ; Luszczynska, A. ; Safron, M. ; Ridder, D.T.D. de - \ 2015
    Public Health Nutrition 18 (2015)6. - ISSN 1368-9800 - p. 1044 - 1051.
    social norms - planned behavior - implementation intentions - health consequences - obesity - consumption - predictors - overweight - childhood - children
    Objective To investigate associations of self-perceived eating-related peer norms (called ‘subjective peer norms’) with adolescents’ healthy eating intentions and intake of healthy and unhealthy food. Design Cross-sectional data were collected in a large international survey Setting Two types of subjective peer norms were assessed: perceived peer encouragement of healthy eating and perceived peer discouragement of unhealthy eating. Outcome variables were healthy eating intentions, intake of healthy food (fruits and vegetables) and intake of unhealthy food (snacks and soft drinks). Subjects Over 2500 European (pre-)adolescents aged between 10 and 17 years participated. Results Subjective peer norms were associated with all three outcome variables. While both perceived encouragement of healthy eating and perceived discouragement of unhealthy eating were related to intentions, only peer encouragement of healthy eating was related to intakes of both healthy and unhealthy food. Conclusions Subjective peer norms play a role in adolescent eating behaviour and as such are an important target for health promotion. Addressing norms that encourage healthy eating may be more promising in changing behaviour than norms that discourage unhealthy eating.
    Effect of a high-protein diet on maintenance of blood pressure levels achieved after initial weight loss: the DiOGenes randomized study
    Engberink, M.F. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Larsen, T. - \ 2015
    Journal of Human Hypertension 29 (2015). - ISSN 0950-9240 - p. 58 - 63.
    risk-factors - controlled-trial - glycemic index - obese women - supplementation - hypertension - overweight - markers - fat
    Randomized trials have shown significant blood pressure (BP) reductions after increased protein compared with carbohydrate intake, but the effect on BP maintenance after initial weight loss is unclear. We examined the effect of a high-protein diet on the maintenance of reduced BP after weight loss in 420 overweight adults from the Diet, Obesity and Genes study. After an 8-week weight-loss period (>8% BW), subjects (42±6 years) were randomized to either a high-protein diet (23–28 en% protein) or a lower-protein control diet (10–15 en% protein) for 26 weeks. BMI after weight loss was 30.3±4.3¿kg¿m-2, BP was 118/73¿mm¿Hg and 28 subjects (6.5%) used antihypertensive agents. Systolic BP during 26 weeks of weight maintenance dietary intervention increased in both treatment groups, but it was 2.2¿mm¿Hg less (95% CI: -4.6 to 0.2¿mm¿Hg, P=0.08) in the high-protein group than in the lower-protein control group. In 191 (pre)hypertensive subjects (baseline systolic BP120¿mm¿Hg), a larger difference was observed (-4.2¿mm¿Hg (-7.7, -0.7), P=0.02). The effect was attenuated after adjustment for initial BP (-3.4¿mm¿Hg (-6.9, -0.03), P=0.048), and after additional adjustment for weight change (-2.7¿mm¿Hg (-6.1, 0.4), P=0.11). Adjustment for 24-h urinary excretion of sodium and potassium did not change the results. Diastolic BP yielded similar results. These findings suggest that a BP reduction after weight loss is better maintained when the intake of protein is increased at the expense of carbohydrates. This effect is partly mediated by body weight.
    Terug in het zadel
    Bouwman, L.I. - \ 2014
    Vork 1 (2014)4. - ISSN 2352-2925 - p. 32 - 36.
    food chains - nutrition and health - overweight - obesity - chronic diseases - consumer behaviour - feeding behaviour - eating - eating patterns - voedselketens - voeding en gezondheid - overgewicht - obesitas - chronische ziekten - consumentengedrag - voedingsgedrag - eten - eetpatronen
    Dreigende epidemieën van overigens niet besmettelijke aandoeningen als obesitas en diabetes type 2 leiden tot - soms tegenstrijdige - aanbevelingen voor gezond eten. Meer groenten, minder vet maar wel meer vette vis, minder rood vlees, meer koolhydraten of juist minder en een Magnum, passen in een gezond dieet. Dat laatste was overigens een advies van de vorige directeur van Unilever dus dat moeten we met een korreltje zout nemen. Hoewel, zout? Mag dat? Volgens Laura Bouwman zijn we terechtgekomen in een situatie van ‘you are what you are told to eat’, waarbij mensen weten dat ze ongezond eten, er ook iets aan willen doen, maar vandaag nog even niet. Ze pleit voor een andere benadering, gericht op verbinding en het bevorderen van het ‘goede leven’.
    Effects of nutritional status and dietetic interventions on survival in Cystic Fibrosis patients before and after lung transplantation
    Hollander, F.M. ; Pierre, D.D. van; Roos, N.M. de; Graaf, E.A. van de; Iestra, J.A. - \ 2014
    Journal of Cystic Fibrosis 13 (2014)2. - ISSN 1569-1993 - p. 212 - 218.
    body-mass index - fat-free mass - percutaneous endoscopic gastrostomy - weight-gain - adults - bioimpedance - candidates - overweight - recipients - impedance
    Background: This study retrospectively investigated nutritional status, dietetic intervention and intake in Cystic Fibrosis (CF) patients before and after lung transplantation (LTX). Methods: Body Mass Index (BMI), Fat Free Mass Index (FFMI) and nutritional intake were retrieved from 75 out-patients aged 15-53 years. Patients were seen every 3-4 months during the waiting list time (range 0-81 months) and up to 116 months after LTX. Survival was measured in months. Results: The median BMI at baseline was 19.2 kg/m(2) (range: 15.3 to 28.4 kg/m(2)) with 29 patients (39%) below = 500 kcal less than recommended. Protein intake was 104 (range 60-187) g or 1.9 g/kg per day. Despite dietetic intervention with oral nutritional supplements (ONS) (36 patients), tube feeding (12 patients), or both (13 patients), HMI and FFMI hardly improved pre-LTX. LTX was performed in 51 patients (68%); 10 patients died during follow-up, median survival time was 41 months. A BMI 18.5 kg/m(2) was more prevalent in patients who died before LTX (6/9) or who died after LTX (4/10) than in patients who were still alive on the waiting list (5/15) or who survived LTX (14/41). Results for FFMI were comparable. From 6-12 months post-LTX, BMI and FFMI markedly improved, especially in underweight patients. Conclusion: A BMI
    Portion Control: Dealing with the supersized food environment
    Poelman, M.P. - \ 2014
    Wageningen University; VU University Amsterdam. Promotor(en): I.H.M. Steenhuis; J.C. Seidell, co-promotor(en): Emely de Vet. - Amsterdam : VU University - ISBN 9789461087942 - 202
    voeding en gezondheid - portiegrootte - overgewicht - obesitas - voedselconsumptie - gewichtsverliezen - nutrition and health - portion size - overweight - obesity - food consumption - weight losses
    In dit proefschrift wordt de voedselomgeving met betrekking tot portiegrootte verkend en wordt er een uitgebreide gewichtsmanagement-interventie gericht op portiecontrole ontwikkeld en geëvalueerd.
    Active video games as a tool to prevent excessive weight gain in adolescents: rationale, design and methods of a randomized controlled trial
    Simons, M. ; Chinapaw, M.J.M. ; Bovenkamp, M. van de; Boer, M.R. de; Seidell, J.C. ; Brug, J. ; Vet, E. de - \ 2014
    BMC Public Health 14 (2014). - ISSN 1471-2458 - 13 p.
    promote physical-activity - sedentary screen time - body-mass index - intrinsic motivation - self-determination - economic burden - obesity - children - overweight - youth
    Background Excessive body weight, low physical activity and excessive sedentary time in youth are major public health concerns. A new generation of video games, the ones that require physical activity to play the games –i.e. active games- may be a promising alternative to traditional non-active games to promote physical activity and reduce sedentary behaviors in youth. The aim of this manuscript is to describe the design of a study evaluating the effects of a family oriented active game intervention, incorporating several motivational elements, on anthropometrics and health behaviors in adolescents. Methods/Design The study is a randomized controlled trial (RCT), with non-active gaming adolescents aged 12 – 16 years old randomly allocated to a ten month intervention (receiving active games, as well as an encouragement to play) or a waiting-list control group (receiving active games after the intervention period). Primary outcomes are adolescents’ measured BMI-SDS (SDS =¿adjusted for mean standard deviation score), waist circumference-SDS, hip circumference and sum of skinfolds. Secondary outcomes are adolescents’ self-reported time spent playing active and non-active games, other sedentary activities and consumption of sugar-sweetened beverages. In addition, a process evaluation is conducted, assessing the sustainability of the active games, enjoyment, perceived competence, perceived barriers for active game play, game context, injuries from active game play, activity replacement and intention to continue playing the active games. Discussion This is the first adequately powered RCT including normal weight adolescents, evaluating a reasonably long period of provision of and exposure to active games. Next, strong elements are the incorporating motivational elements for active game play and a comprehensive process evaluation. This trial will provide evidence regarding the potential contribution of active games in prevention of excessive weight gain in adolescents.
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