Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Current refinement(s):

Records 1 - 20 / 35

  • help
  • print

    Print search results

  • export

    Export search results

  • alert
    We will mail you new results for this query: keywords==quality-of-life
Check title to add to marked list
Effects of shared medical appointments compared to individual appointments in children with atopic dermatitis: A pragmatic randomized controlled trial
Zijlstra, Wieneke T. ; Os-Medendorp, Harmieke van; Fieten, Karin B. ; Sinnema, Gerben ; Bruijnzeel-Koomen, Carla A.F.M. ; Zuithoff, Nicolaas P.A. ; Hoir, Monique P. L'; Pasmans, Suzanne G.M.A. - \ 2019
Clinical and Experimental Allergy 49 (2019)8. - ISSN 0954-7894 - p. 1095 - 1106.
atopic dermatitis - paediatrics - quality-of-life

Background: Atopic dermatitis (AD) needs intensive treatment and has a negative impact on quality of life. Shared medical appointments (SMAs) showed to be effective in clinical outcomes of chronic diseases, but little is known about the effects on children and families. Objective: To evaluate the effects of SMAs compared to individual appointments (IA) for children with AD and their parents on coping and clinical outcomes. Methods: In a pragmatic randomized controlled trial, new patients in UMC Utrecht with AD, younger than 18 years, and their parents were assigned to the SMA group or the IA group using a covariate adaptive randomization method, controlled for age. Before the intervention, 2 months (primary time-point) and 6 months thereafter, we assessed parental emotional coping (primary outcome), quality of life, anxiety about corticosteroids and patient disease activity. Patients, parents and healthcare professionals could not be blinded to group assignment. Results: Of 140 patients, enrolled in the trial, 69 patients were assigned to the SMA and 71 to the IA intervention of whom 114 completed the intervention (SMA: 49; IA: 65). After 2 months, there were no differences between SMAs and IAs in effects on emotional coping: b 0.66, 95% CI −0.7 to 2.03; P = 0.33 (mean difference: 0.30; 95% CI −1.56 to 2.16; N SMA: 11; IA: 24), quality of life, anxiety about corticosteroids and disease activity. From the initial appointment to long-term follow-up, both groups showed substantial improvements, but not significant in disease activity and significant reduction in anxiety about corticosteroids. This study is limited by a low response rate; therefore, linear mixed models and dropout analyses were performed. No serious adverse events were reported. Conclusion and Clinical Relevance: For children with AD and their parents, there were no additional benefits of GMAs in parental emotional coping, anxiety about corticosteroids, quality of life and disease activity. Trial registration:, ISRCTN08506572.

Identifying the methodological characteristics of European green city rankings
Meijering, J.V. ; Kern, K. ; Tobi, H. - \ 2014
Ecological Indicators 43 (2014). - ISSN 1470-160X - p. 132 - 142.
quality-of-life - environmental sustainability - composite indicators - urban areas - construction - pitfalls - indexes
City rankings that aim to measure the environmental sustainability of European cities may contribute to the evaluation and development of environmental policy of European cities. The objective of this study is to identify and evaluate the methodological characteristics of these city rankings. First, a methodology was developed to systematically identify methodological characteristics of city rankings within different steps of the ranking development process. Second, six city rankings European Energy Award, European Green Capital Award, European Green City Index, European Soot-free City Ranking, RES Champions League, Urban Ecosystem Europe were examined. Official websites and any methodological documents found on those websites were content analyzed using the developed methodology. Interviews with representatives of the city rankings were conducted to acquire any additional information. Results showed that the city rankings varied greatly with respect to their methodological characteristics and that all city rankings had methodological weaknesses. Developers of city rankings are advised to use the methodology developed in this study to find methodological weaknesses and improve their ranking. In addition, developers ought to be more transparent about the methodological characteristics of their city rankings. End-users of city rankings are advised to use the developed methodology to identify and evaluate the methodological characteristics of city rankings before deciding to act on ranking results.
Nature and Health
Hartig, T. ; Mitchell, R. ; Vries, S. de; Frumkin, H. - \ 2014
Annual Review of Public Health 35 (2014). - ISSN 0163-7525 - p. 207 - 228.
urban green space - public open space - quality-of-life - physical-activity - mental-health - inner-city - possible mechanism - nature experience - social cohesion - air-quality
Urbanization, resource exploitation, and lifestyle changes have diminished possibilities for human contact with nature in urbanized societies. Concern about the loss has helped motivate research on the health benefits of contact with nature. Reviewing that research here, we focus on nature as represented by aspects of the physical environment relevant to planning, design, and policy measures that serve broad segments of urbanized societies.Wediscuss difficulties in defining “nature” and reasons for the current expansion of the research field, and we assess available reviews. We then consider research on pathways between nature and health involving air quality, physical activity, social cohesion, and stress reduction. Finally, we discuss methodological issues and priorities for future research. The extant research does describe an array of benefits of contact with nature, and evidence regarding some benefits is strong; however, some findings indicate caution is needed in applying beliefs about those benefits, and substantial gaps in knowledge remain.
Long-Term Physical Functioning and Its Association With Somatic Comorbidity and Comorbid Depression in Patients With Established Rheumatoid Arthritis: A Longitudinal Study
Hoek, J. ; Roorda, L.D. ; Boshuizen, H.C. ; Hees, J. van; Rupp, I. ; Tijhuis, G.J. ; Dekker, J. ; Bos, G.A.M. van den - \ 2013
Arthritis Care & Research 65 (2013)7. - ISSN 2151-464X - p. 1157 - 1165.
quality-of-life - chronic disease - health survey - co-morbidity - metaanalysis - prevalence - classification - outcomes - impact - sf-36
ObjectiveTo describe long-term physical functioning and its association with somatic comorbidity and comorbid depression in patients with established rheumatoid arthritis (RA). MethodsLongitudinal data over a period of 11 years were collected from 882 patients with RA at study inclusion. Patient-reported outcomes were collected in 1997, 1998, 1999, 2002, and 2008. Physical functioning was measured with the Health Assessment Questionnaire and the physical component summary score of the Short Form 36 health survey. Somatic comorbidity was measured by a questionnaire including 12 chronic diseases. Comorbid depression was measured with the Center for Epidemiologic Studies Depression Scale. We distinguished 4 groups of patients based on comorbidity at baseline. ResultsSeventy-two percent of the patients at baseline were women. The mean +/- SD age was 59.3 +/- 14.8 years and the median disease duration was 5.0 years (interquartile range 2.0-14.0 years). For the total group of patients with RA, physical functioning improved over time. Patients with somatic comorbidity, comorbid depression, or both demonstrated worse physical functioning than patients without comorbidity at all data collection points. Both groups with comorbid depression had the lowest scores. Only patients with both somatic comorbidity and comorbid depression showed significantly less improvement in physical functioning over time. ConclusionBoth somatic comorbidity and comorbid depression were negatively associated with physical functioning during an 11-year followup period. Furthermore, their combination seems to be especially detrimental to physical functioning over time. These results emphasize the need to take somatic comorbidity and comorbid depression into account in the screening and treatment of patients with RA.
Intestinal microbiota in functional bowel disorders: a Rome foundation report
Simrén, M. ; Barbara, G. ; Flint, H.J. ; Spiegel, B.M. ; Spiller, R.C. ; Vanner, S. ; Verdu, E.F. ; Whorwell, P.J. ; Zoetendal, E.G. - \ 2013
Gut 62 (2013)1. - ISSN 0017-5749 - p. 159 - 176.
quality-of-life - randomized controlled-trial - placebo-controlled trial - chain fatty-acids - 16s ribosomal-rna - multispecies probiotic supplementation - induced visceral hypersensitivity - postinfective gut dysfunction - mucosa-associated microbiota - human col
It is increasingly perceived that gut host-microbial interactions are important elements in the pathogenesis of functional gastrointestinal disorders (FGID). The most convincing evidence to date is the finding that functional dyspepsia and irritable bowel syndrome (IBS) may develop in predisposed individuals following a bout of infectious gastroenteritis. There has been a great deal of interest in the potential clinical and therapeutic implications of small intestinal bacterial overgrowth in IBS. However, this theory has generated much debate because the evidence is largely based on breath tests which have not been validated. The introduction of culture-independent molecular techniques provides a major advancement in our understanding of the microbial community in FGID. Results from 16S rRNA-based microbiota profiling approaches demonstrate both quantitative and qualitative changes of mucosal and faecal gut microbiota, particularly in IBS. Investigators are also starting to measure host-microbial interactions in IBS. The current working hypothesis is that abnormal microbiota activate mucosal innate immune responses which increase epithelial permeability, activate nociceptive sensory pathways and dysregulate the enteric nervous system. While we await important insights in this field, the microbiota is already a therapeutic target. Existing controlled trials of dietary manipulation, prebiotics, probiotics, synbiotics and non-absorbable antibiotics are promising, although most are limited by suboptimal design and small sample size. In this article, the authors provide a critical review of current hypotheses regarding the pathogenetic involvement of microbiota in FGID and evaluate the results of microbiota-directed interventions. The authors also provide clinical guidance on modulation of gut microbiota in IBS
Longevity as an Animal Welfare Issue Applied to the Case of Foot Disorders in Dairy Cattle
Bruijnis, M.R.N. ; Meijboom, F.L.B. ; Stassen, E.N. - \ 2013
Journal of Agricultural and Environmental Ethics 26 (2013)1. - ISSN 1187-7863 - p. 191 - 205.
quality-of-life - locomotion score - milk-production - cows - lameness - behavior - agriculture - systems - lesions - ethics
In current dairy farming it is possible to run a profitable farm without having to adapt the system to the needs of dairy cows. In such systems the interests of the farmer and animals often diverge. Consequently, specific animal welfare problems occur. Foot disorders in dairy cattle are an illustrative example resulting from the specific methods of housing and management in current dairy farming. Foot disorders and the resulting lameness are considered the most important welfare problem in dairy farming. However, these foot disorders not only typify welfare problems related to certain housing systems, but they also lead to the premature culling of cows. The assessment of the impact of foot disorders on the welfare of dairy cows raised the question of whether premature culling affects animal welfare since it affects the longevity of a cow. We argue that this aspect of longevity is morally relevant as an animal welfare issue. In this paper we aim to explore whether longevity is both (a) a morally relevant aspect in the discussion on killing animals and (b) a constitutive element of animal welfare. In other words, we aim to explore whether longevity is an independent moral argument in an animal welfare discussion. We claim that longevity is not merely important as an indicator of animal welfare, but is also a constitutive element of animal welfare. We argue that we need a more integrated approach to animal welfare and that an assessment that includes the aspect of time is necessary. This view involves a shift from views on animal welfare in terms of functioning or feeling well to a view on animal welfare that includes the aspect of natural living in which species-specific development is important. To show the impact of these points of view, we look at the practical implications for choices concerning the management of foot disorders in dairy cattle.
The Effectiveness of Chronic Care Management for Heart Failure: Meta-Regression Analyses to Explain the Heterogeneity in Outcomes
Drewes, H.W. ; Steuten, L.M. ; Lemmens, L.C. ; Baan, C.A. ; Boshuizen, H.C. ; Elissen, A.M. ; Lemmens, K.M. ; Meeuwissen, J.A. ; Vrijhoef, H.J. - \ 2012
Health Services Research 47 (2012)5. - ISSN 0017-9124 - p. 1926 - 1959.
home-based intervention - quality-of-life - randomized controlled-trial - chronic illness care - acute hospital-care - disease-management - clinical-outcomes - elderly-patients - older patients - telephone intervention
Objective To support decision making on how to best redesign chronic care by studying the heterogeneity in effectiveness across chronic care management evaluations for heart failure. Data Sources Reviews and primary studies that evaluated chronic care management interventions. Study Design A systematic review including meta-regression analyses to investigate three potential sources of heterogeneity in effectiveness: study quality, length of follow-up, and number of chronic care model components. Principal Findings Our meta-analysis showed that chronic care management reduces mortality by a mean of 18 percent (95 percent CI: 0.72–0.94) and hospitalization by a mean of 18 percent (95 percent CI: 0.76–0.93) and improves quality of life by 7.14 points (95 percent CI: -9.55 to -4.72) on the Minnesota Living with Heart Failure questionnaire. We could not explain the considerable differences in hospitalization and quality of life across the studies. Conclusion Chronic care management significantly reduces mortality. Positive effects on hospitalization and quality of life were shown, however, with substantial heterogeneity in effectiveness. This heterogeneity is not explained by study quality, length of follow-up, or the number of chronic care model components. More attention to the development and implementation of chronic care management is needed to support informed decision making on how to best redesign chronic care
B vitamins and n-3 fatty acids for brain development and function: review of human studies
Rest, O. van de; Hooijdonk, L.W.A. ; Doets, E.L. ; Schiepers, O.J.G. ; Eilander, J.H.C. ; Groot, C.P.G.M. de - \ 2012
Annals of Nutrition & Metabolism 60 (2012)4. - ISSN 0250-6807 - p. 272 - 292.
alpha-linolenic acid - long-chain omega-3-fatty-acids - randomized controlled-trials - quality-of-life - depressive symptoms - docosahexaenoic acid - alzheimers-disease - folic-acid - cognitive function - fish consumption
Background: Nutrition is one of many factors that affect brain development and functioning, and in recent years the role of certain nutrients has been investigated. B vitamins and n–3 polyunsaturated fatty acids (PUFA) are two of the most promising and widely studied nutritional factors. Methods: In this review, we provide an overview of human studies published before August 2011 on how vitamin B6, folate, vitamin B12 and n–3 PUFA may affect the brain, their nutrient status and the existing evidence for an association between these nutrients and brain development, brain functioning and depression during different stages of the life cycle. Results: No recommendation can be given regarding a role of B vitamins, either because the number of studies on B vitamins is too limited (pregnant and lactating women and children) or the studies are not consistent (adults and elderly). For n–3 PUFA, observational evidence may be suggestive of a beneficial effect; however, this has not yet been sufficiently replicated in randomized controlled trials (RCTs). Conclusions: We found that the existing evidence from observational studies as well as RCTs is generally too limited and contradictory to draw firm conclusions. More research is needed, particularly a combination of good-quality long-term prospective studies and well-designed RCTs
Linking green space to health: a comparative study of two urban neighbourhoods in Ghent, Belgium
Herzele, A. Van; Vries, S. de - \ 2012
Population and Environment 34 (2012)2. - ISSN 0199-0039 - p. 171 - 193.
self-rated health - quality-of-life - physical-activity - multilevel analysis - older-adults - inner-city - possible mechanism - built environment - common spaces - mental-health
This paper investigates the nature of the relationship between the greenness of the local environment and the health and well-being of its inhabitants by looking at a number of possible mediators within the same study: physical activity, perceived stress, ability to concentrate, social cohesion and neighbourhood satisfaction. Data were collected through a survey of residents in two neighbourhoods that differ objectively in green space provision, but which are largely similar in demographics, socio-economic factors, housing conditions and other environmental characteristics, apart from green space. Of the three dependent variables of interest: self-reported general health, bodily functioning and general well-being (happiness), it was self-reported happiness that differed significantly between the two neighbourhoods, with greater happiness in the greener neighbourhood. Amongst the possible mediators, people’s satisfaction with their neighbourhood differed significantly: those living in the greener neighbourhood were more satisfied. Mediation analysis indicated that neighbourhood satisfaction fully mediates the relationship between neighbourhood greenness and happiness. Among the specific (environmental and social) neighbourhood qualities asked about, perception of neighbourhood greenness was found to be the most important predictor of neighbourhood satisfaction. Additional analysis showed that the view from the living room—green or not green—fully mediates the relationship between neighbourhood greenness and neighbourhood satisfaction. This study underscores the importance of nearby green space for people’s overall well-being and suggests the need for green space to be evaluated in terms of visual proximity, that is, whether and how it is experienced from the street and the home
Subjective Welfare, Well-Being, and Self-Reported Food Hypersensitivity in Four European Countries: Implications for European Policy
Voordouw, J. ; Antonides, G. ; Fox, M. ; Cerecedo, I. ; Zamora, J. ; Hoz Caballer, B. de la; Rokicka, E. ; Cornelisse-Vermaat, J.R. ; Jewczak, M. ; Starosta, P. ; Kowalska, M.L. ; Jedrzejczak-Czechowicz, M. ; Vázquez-Cortés, S. ; Escudero, C. ; Flokstra-de Blok, B.M. ; Dubois, A.E.J. ; Mugford, M. ; Frewer, L.J. - \ 2012
Social Indicators Research 107 (2012)3. - ISSN 0303-8300 - p. 465 - 482.
quality-of-life - labeling preferences - allergic consumers - economic costs - health - children - prevalence - income - questionnaire - explanation
This study estimates the effects of food hypersensitivity on individuals’ perceived welfare and well-being compared to non-food hypersensitive individuals. Study respondents were recruited in the Netherlands, Poland, Spain and UK. The difference in welfare between food hypersensitive respondents and those asymptomatic to foods was estimated using a subjective welfare approach, including income evaluation. Well-being was measured using the Cantril Ladder-of-Life Scale, and health status using the Self-Perceived Health Scale. The difference in well-being, welfare and health status between participant groups was explained further using a number of background variables. No significant within-country differences in welfare between food hypersensitive respondents and respondents asymptomatic to foods were found. In terms of well-being, adult food hypersensitive respondents and their spouses reported significantly less happiness than respondents and their spouses asymptomatic to foods in the Netherlands and Poland. In Spain, the spouses of the food hypersensitive respondents were significantly less happy than respondents aymptomatic to foods. The well-being of children did not significantly differ between groups. The degree of severity of food hypersensitivity was negatively related to overall health status. In Poland, food hypersensitive respondents reported worse health status compared to asymptomatic respondents. In Spain, the converse was true. Food hypersensitive respondents were generally less happy with their life as a whole than respondents asymptomatic to foods, presumably because they experienced more negative effects, which were not related to perceived health status
Psychometric properties of the OLQ-13 scale to measure Sense of Coherence in a community-dwelling older population
Naaldenberg, J. ; Tobi, H. ; Hartog-van den Esker, F.G. den; Vaandrager, L. - \ 2011
Health and Quality of Life Outcomes 9 (2011). - ISSN 1477-7525 - 9 p.
quality-of-life - antonovskys sense - 13-item sense - health - questionnaire - salutogenesis - stability - validity - people - adults
Background - With the ongoing demographic shift, the quality of life and health promotion among older individuals are becoming increasingly important. Recent research suggests that Sense of Coherence positively affects quality of life. Hence, a valid and reliable measurement of Sense of Coherence is pivotal. The 13-item Orientation to Life Questionnaire (OLQ-13) can be used to measure Sense of Coherence. The purpose of the present study is to assess the psychometric properties, validity, and reliability, of the OLQ-13 in community-dwelling individuals, aged 65 and older. Methods- The OLQ-13 scale was administered as part of a healthy aging project for non-institutionalized people aged 65 years and older. Internal consistency and reliability were assessed by means of inter-item and test-halves correlations and Cronbach's alpha. Construct validity was explored using cluster analysis and exploratory factor analysis (n = 703) and tested using confirmatory factor analysis on a separate subset of individuals (n = 658). Item face validity was investigated by means of 12 semi-structured interviews. Results - The reliability and the validity of the OLQ-13 in this population of non-institutionalized individuals aged 65 years and older was ambiguous, at least partly due to the poor performance of two items (b and d), which was confirmed by results from the qualitative part of this study. The psychometric properties of the proposed OLQ-11, obtained by deleting the two items, were better. In particular, the interpretation of exploratory factor solution improved. Whereas the underlying theoretical constructs could not be linked to the exploratory analyses of OLQ-13, this was to some extent possible in OLQ-11. The superior validity of OLQ-11 over OLQ-13 was supported by the better model fit in the confirmatory factor analysis. Conclusions - The present mixed-method study suggests the proposed OLQ-11 as a more suitable instrument for measuring Sense of Coherence than the OLQ-13 in a population of ageing individuals. This study confirms that the validity and reliability of OLQ-13 may differ substantially in different populations.
Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms
Jalanka-Tuovinen, J. ; Vos, W.M. de - \ 2011
PLoS ONE 6 (2011)7. - ISSN 1932-6203 - 13 p.
irritable-bowel-syndrome - 16s ribosomal-rna - real-time pcr - gastrointestinal-tract microbiota - human fecal samples - quality-of-life - phylogenetic microarray - gut microbiota - human feces - oxalobacter-formigenes
BACKGROUND: While our knowledge of the intestinal microbiota during disease is accumulating, basic information of the microbiota in healthy subjects is still scarce. The aim of this study was to characterize the intestinal microbiota of healthy adults and specifically address its temporal stability, core microbiota and relation with intestinal symptoms. We carried out a longitudinal study by following a set of 15 healthy Finnish subjects for seven weeks and regularly assessed their intestinal bacteria and archaea with the Human Intestinal Tract (HIT)Chip, a phylogenetic microarray, in conjunction with qPCR analyses. The health perception and occurrence of intestinal symptoms was recorded by questionnaire at each sampling point. PRINCIPAL FINDINGS: A high overall temporal stability of the microbiota was observed. Five subjects showed transient microbiota destabilization, which correlated not only with the intake of antibiotics but also with overseas travelling and temporary illness, expanding the hitherto known factors affecting the intestinal microbiota. We identified significant correlations between the microbiota and common intestinal symptoms, including abdominal pain and bloating. The most striking finding was the inverse correlation between Bifidobacteria and abdominal pain: subjects who experienced pain had over five-fold less Bifidobacteria compared to those without pain. Finally, a novel computational approach was used to define the common core microbiota, highlighting the role of the analysis depth in finding the phylogenetic core and estimating its size. The in-depth analysis suggested that we share a substantial number of our intestinal phylotypes but as they represent highly variable proportions of the total community, many of them often remain undetected. CONCLUSIONS/SIGNIFICANCE: A global and high-resolution microbiota analysis was carried out to determine the temporal stability, the associations with intestinal symptoms, and the individual and common core microbiota in healthy adults. The findings provide new approaches to define intestinal health and to further characterize the microbial communities inhabiting the human gut
Novel foods and allergy: Regulations and risk-benefit assessment
Putten, M.C. van; Kleter, G.A. ; Gilissen, L.J.W.J. ; Gremmen, H.G.J. ; Wichers, H.J. ; Frewer, L.J. - \ 2011
Food Control 22 (2011)2. - ISSN 0956-7135 - p. 143 - 157.
quality-of-life - allergenicity - protein - identification - questionnaire - management - strategy - safety - issues
Hypoallergenic novel foods may have benefits for food-allergic consumers. However, other novel foods may exacerbate the problems associated with food allergy. This paper reviews the existing legislation associated with the introduction of novel foods and specifically considers its coverage of allergy risks and benefits. Various regulations are in place to protect consumer health. These regulations require novel food safety to be assessed before they can enter the market, but do not specify how this assessment, which includes allergenicity, should be performed. It is concluded that including a benefit assessment in the novel food legislation, may be beneficial.
Healthy ageing in a salutogenic way: building the HP 2.0 framework
Lezwijn, J. ; Vaandrager, L. ; Naaldenberg, J. ; Wagemakers, A. ; Koelen, M.A. ; Woerkum, C.M.J. van - \ 2011
Health & Social Care in the Community 19 (2011)1. - ISSN 0966-0410 - p. 43 - 51.
quality-of-life - public-health - coherence - sense - promotion - 21st-century - stability - choices - people - well
Healthy ageing is influenced by a variety of interacting determinants. Because no one agency can tackle all these determinants, the promotion of healthy ageing requires an intersectoral approach. The aim of this article is to describe a theoretical basis, the development and possible applications of a framework within a municipality in the Netherlands. This framework supports intersectoral collaboration by guiding and stimulating the development, implementation and evaluation of health promotion activities for healthy ageing. It is based on the principles of health promotion and on the theory of salutogenesis and built upon three interrelated central concepts: (1) sense of coherence, (2) resources for health, and (3) health. The framework visualises the interrelationships of the three concepts within health promotion and salutogenesis. This visualisation makes explicit the value and the contribution with respect to content of intersectoral collaboration and the participation of older people in health promotion. The relationships between the concepts of the framework also indicate the need to undertake different types of research and gather different kinds of data to develop, implement and evaluate healthy ageing strategies
Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy
Berg, M.G.A. van den; Rasmussen-Conrad, E.L. ; Wei, K.H. ; Lintz-Luidens, H. ; Kaanders, J.H.A.M. ; Merkx, M.A.W. - \ 2010
The British journal of nutrition 104 (2010)6. - ISSN 0007-1145 - p. 872 - 877.
quality-of-life - oral-cancer - impact - malnutrition - therapy - support
Clinical research shows that nutritional intervention is necessary to prevent malnutrition in head and neck cancer patients undergoing radiotherapy. The objective of the present study was to assess the value of individually adjusted counselling by a dietitian compared to standard nutritional care (SC). A prospective study, conducted between 2005 and 2007, compared individual dietary counselling (IDC, optimal energy and protein requirement) to SC by an oncology nurse (standard nutritional counselling). Endpoints were weight loss, BMI and malnutrition (5% weight loss/month) before, during and after the treatment. Thirty-eight patients were included evenly distributed over two groups. A significant decrease in weight loss was found 2 months after the treatment (P=0.03) for IDC compared with SC. Malnutrition in patients with IDC decreased over time, while malnutrition increased in patients with SC (P=0.02). Therefore, early and intensive individualised dietary counselling by a dietitian produces clinically relevant effects in terms of decreasing weight loss and malnutrition compared with SC in patients with head and neck cancer undergoing radiotherapy.
Household costs associated with food allergy: an exploratory study
Voordouw, J. ; Fox, M. ; Cornelisse-Vermaat, J.R. ; Antonides, G. ; Mugford, M. ; Frewer, L.J. - \ 2010
British Food Journal 112 (2010)11. - ISSN 0007-070X - p. 1205 - 1215.
quality-of-life - health - children - impact - questionnaires - framework - europe - adults
Purpose – Food allergy has potential to affect direct, indirect and intangible economic costs experienced by food allergic individuals and their families, resulting in negative impacts on welfare and well-being. The purpose of this paper is to develop an instrument to assess these economic costs of food allergy at household level and to conduct an exploratory analysis of potential economic impact. Design/methodology/approach – A case-controlled postal pilot survey was conducted using a self-completion instrument. Cases had either clinically or self-diagnosed food allergy. Controls were obtained from households in which none of the members had food allergies. Findings – The instrument appeared sensitive to the economic cost differences between households with and without food allergic members. Direct costs of health care were significantly higher for cases than for controls. Similar differences were identified for indirect cost of lost earnings, and costs due to inability to perform domestic tasks because of ill health. Intangible costs (self-reported health status and well-being), indicated significantly lower subjective well-being for cases. Research limitations/implications – Larger sample sizes will be needed to reliably assess the size of impact, cross-cultural variation in costs, and whether costs vary according to severity of food allergy or between diagnosed versus self-reported food allergy. The costs effectiveness of diagnostic methods or interventions may also be assessed using this instrument. If economic costs of food allergy are significant in the population further consideration from a public health policy perspective will be required. Originality/value – To date, economic impact of food allergy on individuals and households has not been quantified. The paper addresses this. Keywords Economics, Personal health, Research and development, The Netherlands, United Kingdom
Day care at green care farms: a novel way to stimulate dietary intake of community-dwelling older people with dementia?
Bruin, S.R. de; Oosting, S.J. ; Tobi, H. ; Blauw, Y.H. ; Schols, J.M.G.A. ; Groot, C.P.G.M. de - \ 2010
Journal of Nutrition, Health and Aging 14 (2010)5. - ISSN 1279-7707 - p. 352 - 357.
nursing-home residents - quality-of-life - food-intake - nutritional assessment - physical-activity - marital-status - weight change - body-weight - appetite - health
Objective - This study aimed to compare dietary intake of older people with dementia receiving day care at regular day care facilities (RDCFs) or at so-called green care farms (GCFs). Design and settings - A comparative cross-sectional study was performed at 10 GCFs and 10 RDCFs in the Netherlands. Participants - 30 subjects from GCFs and 23 subjects from RDCFs, aged 65 years or over, were included in the study. Subjects from GCFs were mostly married males who were aged younger than the subjects from RDCFs who were mostly widowed females. Measurements - Dietary intake of the subjects was observed and/or recorded both at home and during their time at the day care facility. Results - In the GCF group, average total energy intake was significantly higher than in the RDCF group (8.8 MJ/d vs. 7.2 MJ/d). Also total carbohydrates and protein intakes were higher in the GCF group than in the RDCF group (with 257 g/d vs. 204 g/d, and 76 g/d vs. 65 g/d respectively). In addition, average total fluid intake was significantly higher in the GCF group than in the RDCF group (2577 g/d vs. 1973 g/d). Multiple linear regression analyses revealed that after taking possible confounders into account, day care type was still significantly related to the intake of energy, carbohydrates and fluids. Conclusion - This study suggests beneficial effects of this new type of day care on dietary intake by community-dwelling older people with dementia.
Care farms in the Netherlands: Attractive empowerment-oriented and strengths-based practices in the community
Hassink, J. ; Elings, M. ; Zweekhorst, M. ; Nieuwenhuizen, N. van den; Smit, A. - \ 2010
Health & Place 16 (2010)2010. - ISSN 1353-8292 - p. 423 - 430.
quality-of-life - case-management - mental-health - recovery - perspectives - outcomes - people - model
Empowerment-oriented and strengths-based practices focusing on community integration have gained recognition for various client groups in recent decades. This paper discusses whether care farms in the Netherlands are relevant examples of such practices. We identify characteristics associated with care farms that are relevant for three different client groups: clients with severe mental health problems, clients from youth care backgrounds, and frail elderly clients. We interviewed 41 clients, 33 care farmers, and 27 health professionals. The study shows that care farms are experienced as unique services because of a combination of different types of characteristic qualities: the personal and involved attitude of the farmer, a safe community, useful and diverse activities, and a green environment. This leads to an informal context that is close to normal life. We found no essential differences in the assessment of characteristics between different client groups and between clients, farmers, and health professionals. Care farms can be considered as an innovative example of community-based services that can improve the quality of life of clients.Keywords: Care farm; Mental illness; Youth; Elderly; Community care; Empowerment and strength
Low Respiratory Function Increases the Risk of Depressive Symptoms in Later Life in Men
Giltay, E.J. ; Nissinen, A. ; Giampaoli, S. ; Zitman, F.G. ; Kromhout, D. - \ 2010
Psychosomatic Medicine 72 (2010)1. - ISSN 0033-3174 - p. 53 - 60.
obstructive pulmonary-disease - geriatric medical patients - quality-of-life - lung-function - suicidal ideation - follow-up - chronic-bronchitis - cigarette-smoking - united-states - disorders
Objective: To assess the risk of depressive symptoms with respect to respiratory function in middle-aged men. Chronic lung diseases are associated with a high prevalence of depression, but the association of poor respiratory function with depressive symptoms has not been established in prospective population-based cohort studies. Methods: In a prospective, population-based cohort study with up to 30 years of follow-up, we included 1205 men aged 50 to 69 years from Finland (n = 663) and Italy (n = 542). Forced vital capacity (FVC) and forced expiratory flow in 0.75 sec (FEV0.75) in 1970 were analyzed in relationship to depressive symptoms (by Zung self-rating depression scale [SDS]) in 1985, 1990, 1995, and 2000, using multilevel regression models. Subsequent analyses were done separately in the strata with (n = 501) and without (n = 704) chronic diseases in 1970 (i.e., chronic lung diseases, cardiovascular diseases, or diabetes mellitus). Results: Poor respiratory function was associated independently with steeper increases in depressive symptoms over time, both for FVC (p <.001) and FEV0.75 (p = .004). In participants without chronic diseases, a standard deviation (SD) increase in FVC was associated with a 1.1-point decrease (standard error [SE] = 0.4) in Zung SDS (p = .01) and a 1.5-point decrease (SE = 0.4) (p <.001) in participants with chronic diseases (p = .27 for interaction). Low FEV0.75 was associated with more depressive symptoms in participants with chronic diseases (1.7 SE 0.4 decrease per SD; p <.001), but not in participants without chronic diseases (0.6 SE 0.4 decrease per SD; p = .16; p = .008 for interaction). Conclusions: Small lung volumes were associated with an increased risk of subsequent depressive symptoms at old age, especially in persons with chronic lung diseases, cardiovascular diseases, or diabetes mellitus at baseline
Methodological Issues in Primary Prevention Trials for Neurodegenerative Dementia
Andrieu, S. ; Coley, N. ; Aisen, P. ; Carrillo, M.C. ; DeKosky, S. ; Durga, J. ; Fillit, H. ; Frisoni, G.B. ; Froelich, L. ; Gauthier, S. ; Jones, R. ; Jonsson, L. ; Khachaturian, Z. ; Morris, J.C. ; Orgogozo, J.M. ; Ousset, P.J. ; Robert, P. ; Salmon, E. ; Sampaio, C. ; Verhey, F. ; Wilcock, G. ; Vellas, B. - \ 2009
Journal of Alzheimers Disease 16 (2009)2. - ISSN 1387-2877 - p. 235 - 270.
mild cognitive impairment - randomized controlled-trial - placebo-controlled trial - health initiative memory - quality-of-life - mrc/bhf heart protection - population-based cohort - vascular risk-factors - mini-mental state - alzheimers-disease
The prevention of neurodegenerative dementias, such as Alzheimer's disease, is a public health priority. Due to the large numbers of affected patients, even interventions bringing about a relatively small delay in disease onset could have large public health effects. Randomized controlled trials (RCTs) are required to demonstrate the effectiveness of preventive interventions, but such trials raise specific methodological questions because they are new in the field of neurodegenerative diseases, and require large numbers of elderly subjects and lengthy follow-up periods. We performed a literature search to identify primary prevention RCTs for neurodegenerative dementia. The methodology of the trials was summarized and discussed during two expert meetings. Overall, 39 trials were identified that assessed dementia incidence or cognitive decline as a primary or secondary study outcome. Age was the most common selection criteria for target populations. Follow-up periods ranged from one month to nine years and were longest in studies measuring dementia incidence as an outcome. Results of RCTs have so far been generally negative and conflicting with those of observational studies, perhaps due to methodological issues. Future trials must therefore carefully consider the target population, outcomes and duration of follow-up to be used, and should assess the problem of attrition.
Check title to add to marked list
<< previous | next >>

Show 20 50 100 records per page

Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.