Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Insecticide-treated plastic sheeting for emergency malaria prevention and shelter among displaced populations: an observational cohort study in a refugee setting in Sierra Leone
    Burns, M.R. ; Rowland, M. ; N'Guessan, R. ; Carneiro, I. ; Beeche, A. ; Sesler Ruiz, S. ; Kamara, S. ; Takken, W. ; Carnevale, P. ; Allan, R. - \ 2012
    American Journal of Tropical Medicine and Hygiene 87 (2012)2. - ISSN 0002-9637 - p. 242 - 250.
    anopheles-gambiae - rural area - children - vectors - camps - transmission - nets - resistance - exposure - infants
    A double-blind phase III malaria prevention trial was conducted in two refugee camps using pre-manufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp. In Largo camp the ITPS or UPS was attached to inner walls and ceilings of shelters, whereas in Tobanda the ITPS or UPS was used to line only the ceiling and roof. In Largo the Plasmodium falciparum incidence rate in children up to 3 years of age who were cleared of parasites and monitored for 8 months was 163/100 person-years under UPS and 63 under ITPS (adjusted odds ratio [AOR] = 0.40, 95% confidence interval [CI] = 0.33–0.47). In Tobanda incidence was 157/100 person-years under UPS and 134 under ITPS (AOR = 0.85, 95% CI = 0.75–0.95). Protective efficacy was 61% under fully lined ITPS and 15% under roof lined ITPS. Anemia rates improved under ITPS in both camps. This novel tool proved to be a convenient, safe, and long-lasting method of malaria control when used as a full shelter lining in an emergency setting.
    Hitting Hotspots: Spatial Targeting of Malaria for Control and Elimination
    Bousema, T. ; Griffin, J.T. ; Sauerwein, R.W. ; Smith, D.L. ; Churcher, T.S. ; Takken, W. ; Ghani, A. ; Drakeley, C. ; Gosling, R. - \ 2012
    PLOS Medicine 9 (2012)1. - ISSN 1549-1676
    plasmodium-falciparum - anopheles-gambiae - rural area - vector populations - control programs - young-children - urban malaria - west-africa - transmission - infection
    Current malaria elimination guidelines are based on the concept that malaria transmission becomes heterogeneous in the later phases of malaria elimination [1]. In the pre-elimination and elimination phases, interventions have to be targeted to entire villages or towns with higher malaria incidence until only individual episodes of malaria remain and become the centre of attention [1]. With increasing evidence of clustering of malaria episodes within villages, we argue that there is an intermediate step. Heterogeneity in malaria transmission within villages is present long before areas enter the pre-elimination phase, and identifying and targeting hotspots of malaria transmission should form the cornerstone of both successful malaria control and malaria elimination.
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