Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

    Current refinement(s):

    Records 1 - 20 / 165

    • help
    • print

      Print search results

    • export

      Export search results

    Check title to add to marked list
    The transcriptome as early marker of diet-related health : evidence in energy restriction studies in humans
    Bussel, Inge P.G. van - \ 2017
    Wageningen University. Promotor(en): Sander Kersten, co-promotor(en): Lydia Afman. - Wageningen : Wageningen University - ISBN 9789463430678 - 194
    energy restricted diets - energy intake - gene expression - genomes - proteins - endurance - food composition - human nutrition research - energiearme diëten - energieopname - genexpressie - genomen - eiwitten - uithoudingsvermogen - voedselsamenstelling - voedingsonderzoek bij de mens

    Background: Nutrition research is facing several challenges with respect to finding diet related health effects. The effects of nutrition on health are subtle, show high interindividual variations in response, and can take long before they become visual. Recently, the definition of health has been redefined as an organism’s ability to adapt to challenges and ‘this definition’ can be extended to metabolic health. In the metabolic context the ability to adapt has been named ‘phenotypic flexibility’. A potential new tool to magnify the effects of diet on health is the application of challenge tests. Combined with a comprehensive tool such as transcriptomics, the study of challenge tests before and after an intervention might be able to test a change in phenotypic flexibility. A dietary intervention well-known to improve health through weight loss is energy restriction (ER). ER can be used as a model to examine the potential of challenge tests in combination with transcriptomics to magnify diet-induced effects on health. As opposed to ER, caloric restriction (CR) is a reduction in energy intake aimed at improving health and life span in non-obese subjects and not directly aimed at weight loss. In this thesis, we aimed to investigate the use of the transcriptome as an early and sensitive marker of diet-related health.

    Methods: First we studied the consequences of age on the effects of CR on the peripheral blood mononuclear cells (PBMCs) transcriptome. For that purpose, we compared the changes in gene expression in PBMCs from old men with the changes in gene expression in PBMCs from young men upon three weeks of 30% CR. To study the effect of a change in dietary composition during ER, we compared the changes in gene expression upon a 12 weeks high protein 25% ER diet with the changes in gene expression upon a 12 weeks normal protein 25% ER diet in white adipose tissue (WAT). Next, we investigated the added value of measuring the PBMC transcriptome during challenge tests compared to measuring the PBMC transcriptome in the fasted state to magnify the effects of ER on health. This was investigated by measuring the changes in gene expression upon an oral glucose tolerance test (OGTT) and upon a mixed meal test (MMT), both before and after 12 weeks of 20% ER. Finally, we determined the differences between a challenge test consisting of glucose alone, the OGTT, or consisting of glucose plus other macronutrients, the MMT, on the PBMC transcriptome in diet-related health.

    Results: We observed that the transcriptome of PBMCs of healthy young men had a higher responsiveness in immune response pathways compared to the transcriptome of PBMCs of aged men upon CR (chapter 2). Also, we showed that upon a normal protein-ER diet the transcriptome of WAT showed a decrease in pathways involved in immune response and inflammasome, whereas no such effect was found upon a high protein-ER diet. These effect were observed while parameters such as weight loss, glucose, and waist circumference did not change due to the different protein quantities (chapter 3). 12 weeks of 20% ER was shown to increase phenotypic flexibility as reflected by a faster and more pronounced downregulation of OXPHOS, cell adhesion, and DNA replication during the OGTT compared to the control diet (chapter 4). Finally, two challenge tests consisting of either glucose (OGTT) or glucose plus fat and protein (MMT), were shown to result in a larger overlap than difference in the changes in gene expression of PBMCs (chapter 5).

    Conclusions: Based on the differential changes in gene expression upon CR at different ages, we concluded that age is an important modulator in the response to CR. As a high protein ER diet induced transcriptional changes seemed to reflect less beneficial health effects than a normal protein ER diet we concluded that the diet composition is important in the health-effect of ER as measured by the transcriptome. Based on the faster PBMCs changes in gene expression during an OGTT upon 12 weeks of 20% ER, we concluded that the PBMC transcriptome combined with a challenge test can reflect changes in phenotypic flexibility. This makes challenge tests a suitable tool to study diet-related health effects. Finally, based on the changes in gene expression of the MMT and OGTT, we conclude that glucose in a challenge test is the main denominator of the postprandial changes in gene expression in the first two hours. Overall, these results lead to the conclusion that the transcriptome, especially in combination with challenges test, can be used as an early marker of diet-related health. The direct relation to health still needs to be investigated, but the possibility to use the transcriptome as an early marker of diet-related health gives rise to a better understanding of the effects of nutrition on health.

    Het effect van aminozuuraanbod en -samenstelling van het voer op zoötechnische prestaties van beren gehuisvest onder verschillende sanitaire condities
    Meer, Y. van der; Gerrits, W.J.J. ; Jansman, A.J.M. - \ 2016
    Wageningen UR Livestock Research (Livestock Research rapport 938) - 32
    beren (varkens) - aminozuren - eiwit - voedselsamenstelling - varkensvoeding - mestresultaten - hygiëne - varkenshouderij - zoötechniek - dierlijke productie - boars - amino acids - protein - food composition - pig feeding - fattening performance - hygiene - pig farming - zootechny - animal production
    Dit experiment was opgezet om het effect van eiwitniveau (normaal versus verlaagd) en aminozuursamenstelling in het rantsoen te evalueren op de technische prestaties van beren gehuisvest onder een tweetal sanitaire condities.
    Insects as food and feed: nutrient composition and environmental impact
    Oonincx, D.G.A.B. - \ 2015
    Wageningen University. Promotor(en): Arnold van Huis; Joop van Loon. - Wageningen : Wageningen University - ISBN 9789462571785 - 198
    insecten als voedsel - voer - voedselsamenstelling - levenscyclusanalyse - milieueffect - insects as food - feeds - food composition - life cycle assessment - environmental impact


    Because of an increasing world population, with more demanding consumers,

    the demand for animal based protein is on the increase. To meet this increased

    demand, alternative sources of animal based protein are required. When

    compared to conventional production animals, insects are suggested to be an

    interesting protein source because they have a high reproductive capacity, high

    nutritional quality, and high feed conversion efficiency, they can use waste as feed

    and are suggested to be produced more sustainably.

    This thesis starts with a historical perspective on insects as food and feed,

    and explains why insects are expected to be more suitable production animals.

    In Chapter 2 the nutritional quality of insects is discussed based on a

    variety of insects that are commonly used as feed or food. Additionally, various

    environmental and dietary factors which are known to significantly affect insect

    chemical composition are reviewed.

    In Chapter 3 the direct production of greenhouse gases (GHG) and

    ammonia, as well as carbon dioxide emission and average daily weight gain of

    five insect species is quantified. Differences regarding the production of GHGs

    (expressed as CO2 equivalents) between insect species were mainly due to the

    production of methane. All species tested emitted lower amounts of GHG than

    cattle, had a higher growth rate than cattle or pigs, and emitted lower amounts of

    ammonia and either comparable or lower amounts of GHG than pigs.

    Results from Chapter 3 were used in a Life Cycle Assessment conducted

    in Chapter 4. For a mealworm production system total GHG production, energy

    use, and land use were quantified and compared to conventional sources of

    animal protein. This chapter shows that mealworms should be considered a more

    sustainable source of edible protein, and that a large part of their environmental

    impact is due to the feed they consume.

    In Chapter 5 four diets composed from industrial organic by-products

    were formulated such that they varied in protein and fat content. These diets were

    offered to four insect species and their feed conversion efficiency was determined.

    Diets used in large scale production systems were included and served as

    controls. Diet composition affected feed conversion efficiency in all species. It

    is concluded that the four investigated species are efficient production animals

    and can therefore be considered interesting for the production of feed or food.

    Furthermore, diet composition affected insect composition, indicating possibilities

    to tailor the composition of these insects to best meet consumers’ needs.

    In Chapter 6 the suitability of chicken, pig, and cow manure was compared

    as feed for larvae of the Black Soldier Fly, which in turn could be used as feed for

    conventional production animals. Newly hatched larvae were directly inoculated

    on moistened manure. Whereas survival was high on all three tested substrates,

    the development time was greatly prolonged compared to the control diet. On

    pig manure, more nitrogen was utilised than on chicken and cow manure, while P

    utilisation was highest on cow manure. A large proportion of manure nitrogen was

    lost in all treatments, indicating that the production system would require a way

    to prevent this in order to make it ecologically sound. Furthermore, to improve

    economic viability, shorter development times would be required.

    In Chapter 7 the suggestions why insects would make suitable production

    animals are evaluated based on both literature data, and data gathered in this

    thesis. Furthermore, prospects for insects as food or feed are put forward,

    with emphasis on the knowledge and legislation requirements for the further

    development of the insect production sector.

    Saskia van Ruth, Professor of Food Authenticity and Integrity
    Ruth, S.M. van - \ 2014
    Wageningen UR
    voedselanalyse - voedselsamenstelling - voedseltechnologie - authenticiteit - analytische methoden - detectie - food analysis - food composition - food technology - authenticity - analytical methods - detection
    Saskia van Ruth, Professor of Food Authenticity and Integrity, works on analytical methods that make it easier to detect food fraud.
    Traceerbaarheid van grondstoffen in voedingsmiddelen
    Spiegel, M. van der; Roest, J.G. van der; Veer, J.C. van der; Kok, E.J. - \ 2013
    Voeding Nu 3/4 (2013). - ISSN 1389-7608 - p. 12 - 13.
    voedselsamenstelling - vleeswaren - naspeurbaarheid - analytische methoden - industriële grondstoffen - voedselveiligheid - food composition - meat products - traceability - analytical methods - feedstocks - food safety
    Recente incidenten met paardenvlees in voedingsmiddelen laten zien dat bij het etiketteren van complexe voedingsmiddelen, zoals lasagne, fouten worden gemaakt. Juiste informatie over de aard van grondstoffen in voedingsmiddelen is echter van belang voor de keuzevrijheid van consumenten. Dit geldt vooral voor consumenten met specifieke dieetwensen vanwege bijvoorbeeld allergieën, religie, vegetarisme, of de wens om duurzame producten te produceren en consumeren. Kennis van de samenstelling van het product is nodig om fraude te kunnen opsporen.
    Nutrition of grazing cattle in the Mid Rift Valley of Ethiopia: use of an improved n-alkane method to estimate nutrient intake
    Derseh, M.B. - \ 2013
    Wageningen University. Promotor(en): Wouter Hendriks, co-promotor(en): Wilbert Pellikaan; A. Tolera. - S.l. : s.n. - ISBN 9789461734686 - 160
    rundvee - begrazing - weiden - merkers - voedingsstoffenopname (mens en dier) - voedselsamenstelling - voedingswaarde - verteerbaarheid - ruwvoer (roughage) - diervoeding - ethiopië - cattle - grazing - pastures - markers - nutrient intake - food composition - nutritive value - digestibility - roughage - animal nutrition - ethiopia

    Nutrient intake is an important factor that determines the performance of production animals. In free ranging animals, direct measurement of nutrient intake is difficult to conduct, and it is frequently estimated indirectly by the aid of markers. The aim of this thesis was to investigate the potential of using cuticular n-alkanes and their carbon isotope enrichments (δ13C) as markers to study the nutritional ecology of grazing animals under tropical conditions. In addition, this improved method was used to determine the seasonal patterns of nutrient intake and diet composition of grazing cattle in the Mid Rift Valley grasslands of Ethiopia. The first focus of the thesis was to quantify the interspecies variability in the n-alkane profile and δ13C values of alkanes among commonly available pasture species in the Mid Rift Valley of Ethiopia. The analysis showed that the variability is sufficiently large to allow n-alkane and their δ13C values to be used as diet composition markers, with a combined use of the two increasing the discriminatory power. Faecal recovery of dosed and natural alkanes in cattle consuming low-quality tropical roughages was investigated in an indoor balance study. The recovery of synthetic alkanes dosed in the form of molasses boluses was considerably higher than adjacent natural odd-chain alkanes, and correction appears necessary when intake is estimated with the double n-alkane method. The next focus of the thesis was to generate information on the nutritive value of pasture species and nutritional status of grazing cattle in the region. Large variability was observed in the nutritive value and methane production potential of pasture species as evaluated in vitro, with scope for selection of genotypes with high nutritive value and low methane production potential for a sustainable pastureland management. The nutritional status of grazing cattle measured using a combination of n-alkanes, their δ13C values and visual observations showed that diet composition and nutrient intake of the animals is highly dependent on rainfall patterns, with a cyclic positive (wet period) and negative (dry period) energy and nutrient balance observed over the grazing seasons. Energy intake was more limiting than crude protein for body weight gain in most of the grazing seasons. While mature and non-producing animals appeared to tolerate nutritional restriction in the dry period and regain lost body condition in the following wet periods, young animals before the age of puberty may need supplementary feeding. Furthermore, concentrate supplementation of finishing animals needs to coincide with the onset of the wet season to take advantage of compensatory growth. In conclusion, the n-alkanes method coupled with isotope enrichment in n-alkanes and visual observations as used in the present study can provide realistic nutritional data for free-ranging cattle which correlates well with changes in body conditions.

    The kitchen as laboratory : Reflections on the science of food and cooking
    Vega, C. ; Ubbink, J. ; Linden, E. van der - \ 2012
    New York : Columbia University Press - ISBN 9780231153447 - 314
    voedseltechnologie - voeding - voedselanalyse - voedselsamenstelling - eten koken - food technology - nutrition - food analysis - food composition - cooking
    In this global collaboration of essays, chefs and scientists advance culinary knowledge by testing hypotheses rooted in the physical and chemical properties of food. Using traditional and cutting-edge tools, ingredients, and techniques, these pioneers create, and sometimes revamp, dishes that respond to specific desires and serve up an original encounter with gastronomic practice. From the seemingly mundane to the food fantastic the essays in The Kitchen as Laboratory cover a range of creations and their history and culture. They consider the significance of an eater's background and dining atmosphere and the importance of a chef's methods, as well as the strategies used to create a great diversity of foods and dishes.
    Mitofood conference : bioactive food components, energy metabolism and human health, 13-15 April 2011, Wageningen, The Netherlands : celebrating 90 years of human and animal physiology at Wageningen University : final conference of COST Action FA0602: bioactive food components, mitochondrial function and health
    Keijer, J. - \ 2011
    [Wageningen] : Wageningen UR - 87
    voedselsamenstelling - bioactieve verbindingen - voedingsstoffen - energiemetabolisme - gezondheid - polyfenolen - lipiden - vitaminen - hormonen - verouderen - bio-energetica - mitochondria - voeding - food composition - bioactive compounds - nutrients - energy metabolism - health - polyphenols - lipids - vitamins - hormones - aging - bioenergetics - nutrition
    Geitenmelk; de voordelen
    Eekeren, N.J.M. van - \ 2010
    geitenmelk - biologische voedingsmiddelen - voeding en gezondheid - voedselsamenstelling - voedingsstoffen - goat milk - organic foods - nutrition and health - food composition - nutrients
    Geitenmelk heeft een aantal voordelen boven koemelk. Een deel van deze voordelen is wetenschappelijk bewezen en kan gebruikt worden bij de promotie van geitenmelk. Voor een ander deel moet verder onderzoek uitwijzen of de vermoedens kloppen. Dit dossier geeft een overzicht van bewezen en vermoede voordelen.
    Iedereen eet en drinkt elke dag voedsel met E-nummers
    Hartemink, R. - \ 2010
    Over gevoelig heden : kwartaalblad van de Stichting Voedselallergie 26 (2010)4. - ISSN 0928-9127 - p. 22 - 24.
    voedseladditieven - voedselallergieën - voedselintolerantie - stoornissen samenhangend met voedsel - toevoegingen - etiketteren van voedingsmiddelen - voedselsamenstelling - voeding en gezondheid - food additives - food allergies - food intolerance - food-related disorders - additives - nutrition labeling - food composition - nutrition and health
    Soms krijgen mensen met overgevoeligheidsklachten het advies om alle E-nummers in levensmiddelen te mijden. Dat kan helemaal niet! 'Als je dat wilt doen, hou je een dieet over van water, zout en suiker', aldus levensmiddelentechnoloog dr. ir. Ralf Hartemink van Wageningen Universiteit. Dit artikel is een bewerking van zijn lezing tijdens de LustrumDag.
    Voedingsmiddelenanalyses van de Afdeling Humane Voeding: Deel 15. Vetzuursamenstelling van bakkerijmargarines in Nederland 2008
    Hulshof, P.J.M. ; Kosmeyer, T. - \ 2009
    Wageningen : Wageningen Universiteit, Sectie Humane voeding - 13
    margarine - brood- en bakkerijproductenindustrie - voedselsamenstelling - vetzuren - margarine - bakery industry - food composition - fatty acids
    In 2008 werd de vetzuursamenstelling van bakkerijmargarines onderzocht met als doel de voortgang in verbetering van de vetzuursamenstelling in deze producten in beeld te brengen ten opzichte van eerdere bemonsteringen in 1996 en 2004. De vetzuursamenstelling van 14 A-merken bakkerijmargarines afkomstig van drie fabrikanten werd onderzocht. De margarines waren van het type “korst”, “crème”, “wals” of “cake”. De vetzuursamenstelling verschilde nauwelijks tussen de verschillende typen margarine, noch tussen producten van verschillende fabrikanten. Het gehalte verzadigde vetzuren bedroeg gemiddeld 41 g / 100 g product (range: 38–48 g); het gehalte trans-vetzuren was gemiddeld 1 g / 100 g product (range:
    Satiety & Satisfaction : scientific evidence for food products that satisfy and satiate
    Zondervan, C. ; Veer, P. van 't - \ 2009
    Wageningen UR
    verzadigdheid - voedselsamenstelling - voedselonderzoek - voedselwetenschappen - voeding en gezondheid - satiety - food composition - food research - food sciences - nutrition and health
    Information about the R & D programme at Wageningen UR, that focuses on satiety and satisfaction. Globesity can be conquered by making interventions in food composition, producing functional foods, starting dietary programs and educating consumers.
    Pectins and pectinases
    Schols, H.A. ; Visser, R.G.F. ; Voragen, A.G.J. - \ 2009
    Wageningen : Wageningen Academic Publishers - ISBN 9789086861088 - 331
    pectinen - biochemie - plantaardige producten - voedselsamenstelling - pectins - biochemistry - plant products - food composition
    Can diet composition affect behaviour in dogs? : food for thought
    Bosch, G. - \ 2009
    Wageningen University. Promotor(en): Wouter Hendriks; Martin Verstegen, co-promotor(en): Thomas van der Poel; Bonne Beerda. - [S.l. : S.n. - ISBN 9789085853565 - 144
    honden - hondenvoeding - diergedrag - vezels - diëten - voedselsamenstelling - dierfysiologie - dierenwelzijn - voedingsvezels - dogs - dog feeding - animal behaviour - fibres - diets - food composition - animal physiology - animal welfare - dietary fibres
    The consumption of food goes beyond the basic provision of energy and essential nutrients for the maintenance of physical health. Studies in rats, pigs, and human subjects have shown that behaviour and mood can be influenced by specific nutrients consumed. The research described in this thesis aimed to evaluate the impact of dietary composition on two physiological systems involved in the regulation of canine behaviour. In other studies it has been shown that physical activity of pigs can be influenced by dietary fibre type, likely through sustaining satiety after a meal. It appears that the fermentable fibres can stimulate several mechanisms involved in sustaining satiety including the stimulation of the secretion of satiety-related metabolites by the gastrointestinal tract. Furthermore, hunger has been found to influence anxiety in rats. The current study evaluated the potential impact of dietary fibre types for effects on satiety and behaviour in dogs. Two in vitro fermentation studies were conducted to evaluate the microbial fermentation activity in the canine gastrointestinal tract and to screen the fermentability of various fibrous ingredients. Based on these in vitro fermentability data, two diets were formulated expected to differ in fibre fermentability in vivo. The difference in fibre fermentability between diets was confirmed in an in vivo study by evaluation of fibre degradation and concentrations of faecal short-chain fatty acids. In this latter study, the secretion of satiety-related hormones was found not to differ between treatment groups. Feeding dogs a high-fermentable fibre diet did result in a lower motivation to eat 6 hours after their morning meal and a lower activity in their home-kennel compared to dogs fed a low-fermentable fibre diet. Treatment groups did not differ in their responses to short-lasting challenges in a test arena conducted 5 to 7 hours after their morning meal. The second dietary strategy investigated was the use of the essential amino acid tryptophan, the precursor of the neurotransmitter serotonin in the brain. It has been shown that dietary tryptophan supplementation reduces anxiety in rats and increases resilience in dealing with stress in pigs. To investigate if similar effects would occur in dogs, a study was designed and conducted in mildly anxious privately-owned dogs fed diets differing in tryptophan content. Dogs were fed the study diet for 8 weeks using a randomised double-blinded, placebo-controlled design. Intake of the tryptophan supplemented diet increased plasma tryptophan concentrations by 37.4% and its ratio with large neutral amino acids by 31.2% compared to the control diet but the data reported by owners did not show a significant change in the behavioural of the dogs over time that could be attributed to the specific dietary treatment. More controlled behavioural tests conducted on a subset of dogs in both dietary treatment groups failed to show a significant difference of supplementation of the diet with tryptophan. In conclusion, the present work has shown that dietary fibre type can have an impact on canine behaviour through feeding motivation. The measured satiety-related metabolites were not affected by dietary fibre type indicating that other mechanisms were involved in sustaining satiety. Dietary supplementation of tryptophan had no effect on the behaviour of privately-owned dogs.
    Conditie, herkomst en dieet Spiering Kornwerd 2007/2008
    Leeuw, J.J. de; Wiegerinck, J.A.M. - \ 2008
    IJmuiden : IMARES (Rapport / Wageningen IMARES C101/08) - 20
    visbestand - vis - osmerus - voedselsamenstelling - vismigratie - beperking - afsluitdijk - fishery resources - fish - osmerus - food composition - fish migration - restraint - afsluitdijk
    De sterke achteruitgang van spiering in 2008 in het IJsselmeer en Markermeer is voor een belangrijk deel nog onverklaard. Een verslechterde voedselsituatie en beperkte migratiemogelijkheden bij de Afsluitdijk zijn mogelijke oorzaken. In een studie naar de uitspoeling en intrekmogelijkheden van vis door een spuikoker in de Afsluitdijk bij Kornwerd, uitgevoerd in de periode november 2007 tot en met augustus 2008 door Witteveen en Bos in samenwerking met beroepsvissers Manshanden en van Malsum, zijn spieringen verzameld voor nader onderzoek.
    Dieetmarkt slankt zelf af: vraag naar maaltijdvervangers daalt dramatisch: doe maar gewoon lijkt het credo
    Dagevos, H. ; Pronk, A. - \ 2008
    Voedingsmiddelentechnologie 41 (2008)11. - ISSN 0042-7934 - p. 18 - 19.
    maaltijden - vervangmiddelen - vermageringsdiëten - overgewicht - marktonderzoek - reductie - voedselsamenstelling - energetische waarde - consumentengedrag - meals - substitutes - weight loss diets - overweight - market research - reduction - food composition - energy value - consumer behaviour
    Het succes van Sonja Bakker en een groeiende aandacht voor gezondheid wekken de indruk dat we in Nederland massaal aan het lijnen zijn. Het lijkt logisch te veronderstellen dat de markt voor dieetproducten hier garen bij spint en volop in de lift zit. Niets blijkt echter minder waar. Hoewel cijfers zich lastig laten verzamelen, wijzen ze erop dat de afslankbranche allesbehalve big business is
    Beschermen lignanen tegen kanker en hart- en vaatziekten?
    Kuijsten, A. ; Milder, I.E.J. - \ 2008
    Voeding Nu 10 (2008)3. - ISSN 1389-7608 - p. 28 - 30.
    lignanen - fenolverbindingen - oestrogene eigenschappen - hart- en vaatziekten - gezondheidsbescherming - voedselsamenstelling - inname - lignans - phenolic compounds - oestrogenic properties - cardiovascular diseases - health protection - food composition - ingestion
    Lignanen zijn een belangrijke bron van fyto-oestrogenen in onze voeding. De hormoonachtige werking van deze stoffen zou het lichaam kunnen beschermen tegen kanker en hart- en vaatziekten. In Nederland is onderzoek gedaan naar de inname van lignanen en de relatie met deze chronische ziekten. De verbanden die in deze studies gevonden werden, waren niet eenduidig. Mogelijk beschermen lignanen tegen darmkanker in een vroeg stadium van de ziekte, maar hebben ze later weinig effect. In sommige groepen mensen werd echter juist een verhoogd risico gevonden
    Achteruitgang van nutriëntengehalten in voedselgewassen door een verminderde bodemkwaliteit?
    Rietra, R.P.J.J. - \ 2007
    Wageningen : Alterra (Alterra-rapport 1439) - 47
    bodem - bodemdegradatie - bodemvruchtbaarheid - voedingsstoffen - voedselproducten - voedselkwaliteit - voedselsamenstelling - soil - soil degradation - soil fertility - nutrients - food products - food quality - food composition
    Er bestaat maatschappelijke zorg over een mogelijke achteruitgang van het gehalte aan nutriënten in voedsel. De achteruitgang wordt regelmatig toegeschreven aan een verminderde kwaliteit van landbouwgronden. Deze bureaustudie geeft een overzicht over de vraag of er achteruitgang is van de voedselkwaliteit en of die veroorzaakt wordt door een achteruitgang van de bodemkwaliteit of andere factoren
    Lignan intake in the Netherlands and its relation with mortality
    Milder, I.E.J. - \ 2007
    Wageningen University. Promotor(en): Daan Kromhout, co-promotor(en): Peter Hollman; Edith Feskens. - [S.l.] : S.n. - ISBN 9789085046523 - 157
    lignanen - voedselopname - voedselsamenstelling - plantenoestrogenen - mortaliteit - hart- en vaatziekten - neoplasma's - nederland - lignans - food intake - food composition - plant oestrogens - mortality - cardiovascular diseases - neoplasms - netherlands
    KEYWORDS:lignans, phytoestrogens, secoisolariciresinol, liquid chromatography, mass spectrometry, food composition, intake, cancer, cardiovascular diseases, mortality

    Plant lignans are diphenolic compounds that are present in many plant foods. The plant lignans lariciresinol (LARI), pinoresinol (PINO), secoisolariciresinol (SECO), and matairesinol (MAT) are efficiently converted into enterolignans by the intestinal microflora. Enterolignans possess several biological activities, e.g. antioxidant and estrogen-like activities by which they may reduce the risk of chronic diseases. Studies on the health effects of lignans were hampered by the lack of comprehensive data on the lignan contents of foods and diets.

    Therefore, we developed a liquid chromatography-tandem mass spectrometry method to measure these four lignans in foods and beverages; and we constructed a lignan database with lignan contents of 83 solid foods and 26 beverages commonly consumed in theNetherlands. Almost all plant foods contained lignans. The most abundant lignan sources were flaxseed (≈ 300 mg/100 g; mainly SECO); and sesame seeds (≈ 40 mg/100 g; mainly PINO). The lignan contents of grain products, vegetables, fruits and legumes varied mostly between 50 and 200 µg/100 g.Highervalues were found for Brassica vegetables, garlic, French beans, apricots, strawberries, and peaches. Lignan contents in beverages ranged from 0 for cola to 91 µg/100 ml for red wine.

    The median total lignan intake among a representative sample of Dutch adults was979 µg/d (range 43-77 584 µg/d). LARI plus PINO contributed 75% to the lignan intake, whereas SECO plus MAT only 25%. Remarkably, the major food sources of lignans were beverages (37%), followed by vegetables (24%), nuts and seeds (14%), bread (9%) and fruits (7%).

    Besides the consumption of lignan-rich foods, the major determinants of plasma enterolignan concentrations in an endoscopy-based population of 637 adults were defecation frequency, smoking, and body weight. The correlation between total lignan intake and plasma enterolignans was modest ( r s = 0.18).

    In a prospective cohort study, in which 570 men aged 64-84 y were followed for 15 y, total lignan intake was not related with mortality. However, intake of MAT was inversely associated with coronary heart disease, cardiovascular diseases, cancer, and all-cause mortality. Multivariate adjusted rate ratios (95% CI) per 1-SD increase in intake were 0.72 (0.53-0.98) for CHD, 0.83 (0.69-1.00) for CVD, 0.81 (0.65-1.00) for cancer, and 0.86 (0.76-0.97) for all-cause mortality. Before conclusions can be drawn, these results need to be confirmed in other prospective studies.
    Voedingsmiddelenanalyses van de Afdeling Humane Voeiding. Deel 14 Vetzuursamenstelling van frituurvetten en bakkerijmargarines in Nederland in 2004
    Hulshof, P.J.M. ; Kosmeyer, T. ; Siebelink, E. ; Katan, M.B. - \ 2005
    Wageningen : Wageningen Universiteit, Sectie Humane voeding - 18
    voedingsmiddelen - chemische samenstelling - vetten - oliën - bakoliën - bakvetten - boter - margarine - voedingswaarde - voedsel - voedselsamenstelling - kwaliteit - eigenschappen - huishoudens - ziekenhuizen - ziekenhuiscatering - verpleeghuizen - dierlijke producten - ingrediënten - Ghana - Filippijnen - spijsoliën - spijsvetten - institutionele huishoudens - foods - chemical composition - fats - oils - cooking oils - cooking fats - butter - margarine - nutritive value - food - food composition - quality - properties - households - hospitals - hospital catering - nursing homes - animal products - ingredients - Ghana - Philippines - edible oils - edible fats - institutional households
    Check title to add to marked list
    << previous | next >>

    Show 20 50 100 records per page

    Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.