Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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The Cdk1/Cdk2 homolog CDKA;1 controls the recombination landscape in Arabidopsis
Wijnker, Erik ; Harashima, Hirofumi ; Müller, Katja ; Parra-Nuñez, Pablo ; Bastiaan de Snoo, C. ; Belt, Jose van de; Dissmeyer, Nico ; Bayer, Martin ; Pradillo, Monica ; Schnittger, Arp - \ 2019
Proceedings of the National Academy of Sciences of the United States of America 116 (2019)25. - ISSN 0027-8424 - p. 12534 - 12539.
Class - Cross-over interference - Crossovers - Cyclin-dependent kinase - Meiosis - Meiotic recombination

Little is known how patterns of cross-over (CO) numbers and distribution during meiosis are established. Here, we reveal that cyclin-dependent kinase A;1 (CDKA;1), the homolog of human Cdk1 and Cdk2, is a major regulator of meiotic recombination in Arabidopsis. Arabidopsis plants with reduced CDKA;1 activity experienced a decrease of class I COs, especially lowering recombination rates in centromere-proximal regions. Interestingly, this reduction of type I CO did not affect CO assurance, a mechanism by which each chromosome receives at least one CO, resulting in all chromosomes exhibiting similar genetic lengths in weak loss-of-function cdka;1 mutants. Conversely, an increase of CDKA;1 activity resulted in elevated recombination frequencies. Thus, modulation of CDKA;1 kinase activity affects the number and placement of COs along the chromosome axis in a dose-dependent manner.

Artificial intelligence in greenhouses - Autonomous Greenhouse Challenge 2018
Hemming, Silke - \ 2018
Do theories of change enable innovation platforms and partnerships to navigate towards impact?
Vellema, S. ; Maru, Y.T. ; Ekong, J. ; McNamara, P. ; Waters-Bayer, A. ; Watson, D. ; Brouwers, J.H.A.M. - \ 2017
Royal Tropical Institute (KIT Working papers 2017-13) - 8 p.
Nieuw middel tegen de Varroamijt beschikbaar
Blacquiere, T. - \ 2017
Nieuwsbrief van bijen@wur (2017)36.
Sinds deze zomer is er een nieuw bestrijdingsmiddel tegen de varroamijt in bijenvolken beschikbaar, Polyvar Yellow®, met als actieve stof het pyrethroïde Flumethrin. Het middel wordt geproduceerd door Bayer Animal Health, die eerder al op basis van dezelfde stof ‘Bayvarol’ op de markt bracht. Het speciale aan de huidige toepassing is dat het middel in een plastic strip is verwerkt die als poort in de ingang van de kast kan worden geplaatst, door gaten in de strip lopen de bijen in en uit de kast en nemen daarmee de actieve stof op.
Plant resistance mechanisms to cyst nematodes
Goverse, Aska - \ 2017
Webinar
Insights in the evolution of plant parasitism among nematodes & practical spin off
Helder, Hans - \ 2017
Webinar
Veel te leren op Bayer-proevenplatform
Brouwer, Thie Arend - \ 2017
How can external interventions build on local innovations? : Lessons from an assessment of innovation experiences in African smallholder agriculture
Triomphe, Bernard ; Floquet, Anne ; Letty, Brigid ; Kamau, Geoffrey ; Almekinders, Conny ; Waters-Bayer, Ann - \ 2017
In: Sustainable Intensification in Smallholder Agriculture: An Integrated Systems Research Approach / Oborn, Ingrid, Vanlauwe, Bernard, Phillips, Michael, Thomas, Richard, AttaKrah, Kwesi, Brooijmans, Willemien, Taylor and Francis Inc. - ISBN 9781138668089 - p. 334 - 366.
Red mud as secondary source for critical raw materials - purification of rare earth elements by liquid/liquid extraction
Ujaczki, Éva ; Zimmermann, Yannick ; Gasser, Christoph ; Molnár, Mónika ; Feigl, Viktória ; Lenz, Markus - \ 2017
Journal of Chemical Technology and Biotechnology 92 (2017)10. - ISSN 0268-2575 - p. 2683 - 2690.
Critical raw materials - Purification - Rare earth - Red mud - Systematic approach
BACKGROUND: Critical raw materials (CRM) are crucial to Europe's economy and essential to maintaining and improving our quality of life due to their usage for production of many devices. Red mud is generated from alumina production where bauxite is digested in hot sodium hydroxide solution during the Bayer process. Red mud can contain considerable amounts of CRM such as rare earth elements (REEs). In the present study, purification of CRM from perturbing, co-extracted elements such as Fe and Al from red mud hydrochloric acid leachates was evaluated. RESULTS: A first purification was achieved by removing Fe (>87%) from the acidic leachate using precipitation with NaOH. REEs as well as Al were hardly removed by precipitation (21%, and 33%, resp.). A second purification was achieved using liquid/liquid extraction (LLE) with di-(2-ethylhexyl)phosphoric acid (D2EHPA). Here, four explanatory variables (i.e. LLE organic/aqueous ratio, D2EHPA concentration in kerosene, stripping acid organic/aqueous ratio, HCl concentration) were studied. Finally, the optimal extraction conditions maximizing the economic potential (total metal extracted×economic value of the respective metal) of CRM were determined using a design of experiment approach. CONCLUSION: The experimentally determined economic potential extracted corresponded well to the prediction (88%; to the predictions, maximum recovery of 17.18±0.59 US $ t-1). Ultimately, more than 40% of the overall REEs (>62% of the leachable REEs) in red mud were purified using LLE, whereas Al was successfully rejected from the concentrate (∼5% of the overall Al present).
Red mud as secondary source for critical raw materials - extraction study
Ujaczki, Éva ; Zimmermann, Yannick S. ; Gasser, Christoph A. ; Molnár, Mónika ; Feigl, Viktória ; Lenz, Markus - \ 2017
Journal of Chemical Technology and Biotechnology 92 (2017)11. - ISSN 0268-2575 - p. 2835 - 2844.
Critical raw materials - Extraction - Rare earth - Red mud - Systematic approach
BACKGROUND: Red mud is a by-product of alumina extraction from bauxite by the Bayer process produced in the billion tons scale worldwide. Red muds, or more generally bauxite residues, are regarded as waste, but may potentially be valuable sources of critical raw materials (CRM). In the present study both conventional extracting agents (mineral acids) and small molecular weight complexing agents (organic acids) were evaluated regarding their efficiency to extract CRM such as rare earth elements (REEs) from red mud. On a molar base, highest extraction efficiencies for REEs were achieved using HCl compared with the other acids investigated. Consequently, an experimental design approach was used to determine optimal conditions for CRM extraction using HCl. Instead of maximizing the extraction of a number of selected metals, the maximum economic potential as the sum of all metals (total metal extracted×economic value of the respective metal) was chosen as the application relevant response variable. Four explanatory variables (i.e. HCl concentration, contact time, temperature and slurry concentration) were used. RESULTS: Optimal conditions maximizing the economic potential were predicted for 5.60molL-1 HCl, 24h contact time, 73.4°C, and 100gL-1 slurry concentration. Indeed, experimentally determined economic potential corresponded well (96% of predicted) with the predictions, allowing a maximum recovery of 40.95±0.90 US $ t-1. CONCLUSION: Though the studied red muds were relatively low in CRM concentrations, the systematic approach developed here allows straightforward transfer to other red muds, harnessing the potential of the latter as important secondary source for CRM.
Uncertainties in the land-use flux resulting from land-use change reconstructions and gross land transitions
Bayer, Anita D. ; Lindeskog, Mats ; Pugh, Thomas A.M. ; Anthoni, Peter M. ; Fuchs, Richard ; Arneth, Almut - \ 2017
Earth System dynamics 8 (2017)1. - ISSN 2190-4979 - p. 91 - 111.
Land-use and land-cover (LUC) changes are a key uncertainty when attributing changes in measured atmospheric CO2 concentration to its sinks and sources and must also be much better understood to determine the possibilities for land-based climate change mitigation, especially in the light of human demand on other land-based resources. On the spatial scale typically used in terrestrial ecosystem models (0.5 or 1°) changes in LUC over time periods of a few years or more can include bidirectional changes on the sub-grid level, such as the parallel expansion and abandonment of agricultural land (e.g. in shifting cultivation) or cropland–grassland conversion (and vice versa). These complex changes between classes within a grid cell have often been neglected in previous studies, and only net changes of land between natural vegetation cover, cropland and pastures accounted for, mainly because of a lack of reliable high-resolution historical information on gross land transitions, in combination with technical limitations within the models themselves. In the present study we applied a state-of-the-art dynamic global vegetation model with a detailed representation of croplands and carbon–nitrogen dynamics to quantify the uncertainty in terrestrial ecosystem carbon stocks and fluxes arising from the choice between net and gross representations of LUC. We used three frequently applied global, one recent global and one recent European LUC datasets, two of which resolve gross land transitions, either in Europe or in certain tropical regions. When considering only net changes, land-use-transition uncertainties (expressed as 1 standard deviation around decadal means of four models) in global carbon emissions from LUC (ELUC) are ±0.19, ±0.66 and ±0.47 Pg C a−1 in the 1980s, 1990s and 2000s, respectively, or between 14 and 39 % of mean ELUC. Carbon stocks at the end of the 20th century vary by ±11 Pg C for vegetation and ±37 Pg C for soil C due to the choice of LUC reconstruction, i.e. around 3 % of the respective C pools. Accounting for sub-grid (gross) land conversions significantly increased the effect of LUC on global and European carbon stocks and fluxes, most noticeably enhancing global cumulative ELUC by 33 Pg C (1750–2014) and entailing a significant reduction in carbon stored in vegetation, although the effect on soil C stocks was limited. Simulations demonstrated that assessments of historical carbon stocks and fluxes are highly uncertain due to the choice of LUC reconstruction and that the consideration of different contrasting LUC reconstructions is needed to account for this uncertainty. The analysis of gross, in addition to net, land-use changes showed that the full complexity of gross land-use changes is required in order to accurately predict the magnitude of LUC change emissions. This introduces technical challenges to process-based models and relies on extensive information regarding historical land-use transitions
De aardappel is gezonder dan we denken
Meer, Ingrid van der - \ 2017
Mieux évaluer et accompagner l’innovation agricole en Afrique. Leçons d’une analyse transversale de 13 cas d’études
Triomphe, Bernard ; Floquet, Anne ; Letty, Brigid ; Kamau, Geoffrey ; Almekinders, Conny ; Waters-Bayer, Ann - \ 2016
Cahiers Agricultures 25 (2016)6. - ISSN 1777-5949 - 11 p.
This paper presents insights gained from a cross-analysis of 13 agricultural innovation experiences in three African countries (Benin, Kenya and South Africa). The participatory assessment was conducted with a common analytical framework and inspired by the agricultural innovation system (AIS) perspective and focused on understanding how innovation unfolded over time as a result of diverse triggers and drivers under the influence of a diversity of stakeholders. Conducted by teams involving researchers, students and local stakeholders, the assessment involved semi-structured interviews, focus-group discussions and multi-stakeholder workshops. The cases cover a wide diversity of experiences in terms of types and domains, scales, timelines, initiators of innovation and stakeholders involved. Findings show the diversity of stakeholders engaged in innovation, and the nature of the innovation triggers and drivers. They also show the importance of taking into account a longer-term perspective (one or several decades) to truly understand innovation processes. Finally, they show that the influence of external interventions on innovation can be both positive and problematic. In particular, questions arise about the capacity to institutionalize innovation beyond the time frame of projects or the capacity to interact with local innovation dynamics. The paper proposes different avenues for improving approaches to assess and support innovation. This includes revisiting the modalities used to conceive and fund external interventions, and developing the necessary skills and capacities to implement open-ended, flexible approaches over the long-term, building as much as possible on initiatives undertaken by the local stakeholders themselves.
Making sense of innovation processes in african smallholder agricullture
Triomphe, B. ; Floquet, A. ; Kamau, G. ; Letty, B. ; Almekinders, C.J.M. ; Waters-Bayer, A. - \ 2016
In: Innovation systems / Francis, J., Mytelka, L., van Huis, A., Röling, N., Wageningen : The Technical Centre for Agricultural and Rural Cooperation (CTA) - ISBN 9789290815617 - p. 170 - 182.
The European-funded Framework Programme 7 project, Joint Learning in Innovation Systems in African Agriculture (JOLISAA), assessed agricultural innovation experiences focused on smallholders in Benin, Kenya, and South Africa. Fifty-six cases were characterized through review of grey literature and interviews with resource persons, according to a common analytical framework inspired by the innovation systems (IS) perspective. Thirteen of the cases were assessed in greater depth through semi-structured interviews, focus group discussions and multistakeholder workshops. The cases covered a wide diversity of experiences in terms of types, domains, scales, timelines, initiators of innovation and stakeholders involved. Findings revealed multiple triggers and drivers of innovation. For external stakeholders, key triggers included likelihood of offering a technological fix to an existing problem and availability of funding. For local people, access to input and output markets was a powerful trigger and driver. Market types and dynamics varied greatly. Developing functional value chains and accessing markets proved particularly challenging, especially for poorer and weakly organized farmers. Over long periods, determinants of innovation changed dynamically and often unpredictably, including motivations of key stakeholders, triggers, drivers and stakeholder arrangements. The direction of innovation evolved, often moving from a technology entry point to more organizational or institutional issues. A recurring challenge for fostering innovation is whether and how to build on local initiatives and knowledge, and how to sustain externally driven innovation processes beyond the project time frame. A major conclusion from JOLISAA is that innovation has to be seen as a continuously evolving process of ‘innovation bundles’ (a combination of different types of innovation) of various kinds, rather than as a pre-planned, and usually, narrowly-defined technical intervention. Consequently, open-ended, flexible approaches to innovation are needed with the potential to engage meaningfully over a long time with local stakeholders and bearers of local innovation dynamics, so that they take full charge of the innovation process and direction.
Cross-industry Collaborations in the Convergence Area of Functional Foods
Bornkessel, S. ; Broring, Stefanie ; Omta, S.W.F. - \ 2016
International Food and Agribusiness Management Review 19 (2016)2. - ISSN 1096-7508 - p. 75 - 98.
cross-industry collaborations, convergence, food industry, pharmaceutical industry
Convergence processes are based on the activity of distinct industry sectors showing crossindustry
collaborations. The aim of this paper is to analyze cross-industry collaborations between
the food and pharmaceutical sectors in the convergence area of functional foods. Selected
companies from food (Nestlé/Danone) and pharmaceutical (Martek/Bayer HealthCare) sectors
are analyzed using the determinants of motivation and industrial scope. The analysis shows that
food companies are more active in cross-industry collaborations than pharmaceutical companies.
The latter are more active at the front-end of the value chain focusing on research and
development, and delivering their ingredients to food companies that due to their higher
expertise in consumer marketing launch the products. While the first cross-industry
collaborations were based on an exploration motivation, those that follow focus on exploitation.
Acquisitions and licensing agreements are dominant in inside-out and outside-in processes,
whereas strategic alliances and joint ventures are based on a coupled process between the food
and pharmaceutical sectors.
Initial recommendations for higher-tier risk assessment protocols for bumble bees, Bombus spp. (Hymenoptera: Apidae)
Cabrera, A.R. ; Almanza, M.T. ; Cutler, G.C. ; Fischer, D.L. ; Hinarejos, S. ; Lewis, G. ; Nigro, D. ; Olmstead, A. ; Overmyer, J. ; Potter, D.A. ; Raine, N.E. ; Stanley-Stahr, C. ; Thompson, H. ; Steen, J.J.M. van der - \ 2016
Integrated Environmental Assessment and Management 12 (2016)2. - ISSN 1551-3793 - p. 222 - 229.
Global declines of bumble bees and other pollinator populations are of concern because of their critical role for crop production and maintenance of wild plant biodiversity. Although the consensus among scientists is that the interaction of many factors, including habitat loss, forage scarcity, diseases, parasites, and pesticides, potentially plays a role in causing these declines, pesticides have received considerable attention and scrutiny. In response, regulatory agencies have introduced more stringent pollinator testing requirements for registration and reregistration of pesticides, to ensure that the risks to pollinators are minimized. In this context, guidelines for testing bumble bees (Bombus spp.) in regulatory studies are not yet available, and a pressing need exists to develop suitable protocols for routine higher-tier studies with these non-Apis sp., social bees. To meet this need, Bayer CropScience LP, Syngenta Crop Protection LLC US, and Valent U.S.A. Corporation organized a workshop bringing together a group of global experts on bumble bee behavior, ecology, and ecotoxicology to discuss and develop draft protocols for both semi-field (Tier II) and field (Tier III) studies. The workshop was held May 8-9, 2014, at the Bayer Bee Care Center, North Carolina, USA. The participants represented academic, consulting, and industry scientists from Europe, Canada, the United States, and Brazil. The workshop identified a clear protection goal and generated proposals for basic experimental designs, relevant measurements, and endpoints for both semi-field (tunnel) and field tests. These initial recommendations are intended to form the basis of discussions to help advance the development of appropriate protocol guidelines
Precisielandbouw; stand van zaken en toekomstperspectief
Kempenaar, Corne - \ 2015
Rekening houden met meer plagen in maïs
Groten, J.A.M. - \ 2015
Bayer CropScience SA-NV
PPO Valthermond aan de slag met easyFlow : PPO Valthermond
Hoekzema, G.A. - \ 2015
Bayer CropScience SA-NV
Wageningen UR gaat samen met Nederlandse imkers onderzoek doen naar nieuw middel tegen varroamijten
Blacquiere, T. - \ 2014
Nieuwsbrief van bijen@wur (2014).
Onderzoekers van bijen@wur van Wageningen UR gaan samen met Nederlandse imkers onderzoek doen naar de werkzaamheid en de veiligheid van een nieuw middel voor de bestrijding van varroa-mijten bij honingbijen. Daarmee willen de onderzoekers een bijdrage leveren aan de gezondheid van honingbijenvolken in Nederland en daarbuiten. Het gaat om onderzoek naar de werkzaamheid en de veiligheid van de “Varroa-gate” van Bayer HealthCare Animal Health, het bedrijf dat de varroa-gate als diergeneesmiddel voor bijen op de markt wil gaan brengen. Het onderzoek dat Wageningen UR samen met de Nederlandse imkers gaat doen is onderdeel van het wettelijk noodzakelijke onderzoek bij de toelating van nieuwe diergeneesmiddelen in de EU en wordt daarom gefinancierd door Bayer.
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