Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Records 1 - 14 / 14

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    Genome expansion of Arabis alpina linked with retrotransposition and reduced symmetric DNA methylation
    Willing, Eva Maria ; Rawat, Vimal ; Mandáková, Terezie ; Maumus, Florian ; James, Geo Velikkakam ; Nordström, Karl J.V. ; Becker, Claude ; Warthmann, Norman ; Chica, Claudia ; Szarzynska, Bogna ; Zytnicki, Matthias ; Albani, Maria C. ; Kiefer, Christiane ; Bergonzi, Sara ; Castaings, Loren ; Mateos, Julieta L. ; Berns, Markus C. ; Bujdoso, Nora ; Piofczyk, Thomas ; Lorenzo, Laura De; Barrero-Sicilia, Cristina ; Mateos, Isabel ; Piednoël, Mathieu ; Hagmann, Jörg ; Chen-Min-Tao, Romy ; Iglesias-Fernández, Raquel ; Schuster, Stephan C. ; Alonso-Blanco, Carlos ; Roudier, François ; Carbonero, Pilar ; Paz-Ares, Javier ; Davis, Seth J. ; Pecinka, Ales ; Quesneville, Hadi ; Colot, Vincent ; Lysak, Martin A. ; Weigel, Detlef ; Coupland, George ; Schneeberger, Korbinian - \ 2015
    Nature Plants 1 (2015). - ISSN 2055-026X - 7 p.
    Despite evolutionary conserved mechanisms to silence transposable element activity, there are drastic differences in the abundance of transposable elements even among closely related plant species. We conducted a de novo assembly for the 375 .Mb genome of the perennial model plant, Arabis alpina. Analysing this genome revealed long-lasting and recent transposable element activity predominately driven by Gypsy long terminal repeat retrotransposons, which extended the low-recombining pericentromeres and transformed large formerly euchromatic regions into repeat-rich pericentromeric regions. This reduced capacity for long terminal repeat retrotransposon silencing and removal in A. alpina co-occurs with unexpectedly low levels of DNA methylation. Most remarkably, the striking reduction of symmetrical CG and CHG methylation suggests weakened DNA methylation maintenance in A. alpina compared with Arabidopsis thaliana. Phylogenetic analyses indicate a highly dynamic evolution of some components of methylation maintenance machinery that might be related to the unique methylation in A. alpina.
    Dietary and other determinants of lipoprotein levels within a population of 315 Dutch males aged 28 and 29.
    Berns, M.A.M. ; Vries, J.H.M. de; Katan, M.B. - \ 1990
    European Journal of Clinical Nutrition 44 (1990). - ISSN 0954-3007 - p. 535 - 544.
    De verhouding tussen ecologie en economie.
    Dijk, G. van - \ 1990
    In: Om het beheer van de Schepping / Berns, R.M.M., - p. 57 - 75.
    Relation between the increase of serum cholesterol with age and short-term susceptibility of serum cholesterol to dietary fat and cholesterol in man.
    Berns, M.A.M. ; Vries, J.H.M. de; Katan, M.B. - \ 1989
    Nutrition reports international 40 (1989). - ISSN 0029-6635 - p. 289 - 303.
    Increase in body fatness as a major determinant of changes in serum total and HDL-cholesterol in young men over a 10-year period.
    Berns, M.A.M. ; Vries, J.H.M. de; Katan, M.B. - \ 1989
    American Journal of Epidemiology 130 (1989). - ISSN 0002-9262 - p. 1109 - 1122.
    Cigarette smoking and linoleic acid.
    Berns, M.A.M. ; Katan, M.B. - \ 1989
    The Lancet 2 (1989)8657. - ISSN 0140-6736 - p. 275 - 276.
    Determinants of the serum cholesterol increase with age, a longitudinal study.
    Berns, M.A.M. ; Vries, J.H.M. de; Katan, M.B. - \ 1988
    International Journal of Epidemiology 17 (1988). - ISSN 0300-5771 - p. 789 - 796.
    In Western populations, the level of serum cholesterol increases with age, whereas in certain developing countries this increase is absent. In order to determine which factors are related to this increase, the authors investigated 99 men and 70 women whose serum cholesterol, habitual food intake, and body mass index were measured between 1974 and 1979 when they were students (baseline values) and again in 1985 (follow-up measurement). Serum cholesterol had increased by 0.59 mmol/l (14%) in men, and by 0.34 mmol/l (7%) in women. The effect of changes in habitual food intake on serum cholesterol was quantified as the Keys score. The mean increase of the Keys score corresponded to a change in cholesterol of 0.12 mmol/l for both men and women. Body mass index had increased by 0.9 kg/m2 in men and by 0.5 kg/m2 in women. Regression analysis showed that in men change in body mass index partly explained the change in serum cholesterol (r = 0.20). In women none of the independent variables could explain changes in serum cholesterol. In order to determine what the effect of ageing was independent of changes in body mass index and dietary changes, 34 volunteers who had participated in the follow-up measurements and whose change in body mass index had been less than 2 kg/m2, were prescribed a diet for three weeks. This diet had the same composition as their habitual diet at baseline measurement. It lowered serum cholesterol levels by 0.1 mmol/l over the three weeks of the trial, and thus could not abolish the rise of serum cholesterol with age.
    Congruence of individual responsiveness to dietary cholesterol and to saturated fat in man.
    Katan, M.B. ; Berns, M.A.M. ; Glatz, J.F.C. ; Knuiman, J.T. ; Nobels, A. ; Vries, J.H.M. de - \ 1988
    Journal of Lipid Research 29 (1988). - ISSN 0022-2275 - p. 883 - 892.
    Previous experiments have shown that differences between humans in the response of serum cholesterol to dietary cholesterol are at least partly reproducible and stable over a prolonged period. In this study it was investigated whether enhanced sensitivity to dietary cholesterol and saturated fat go together. The subjects had also participated in three or four experiments dealing with the reproducibility of the effect on blood cholesterol of either adding cholesterol to the diet in normal subjects (NORM-EGG group; n = 23) or of cessation of egg consumption in subjects with a high habitual egg intake (HAB-EGG group; n = 24). In the present experiment the NORM-EGG subjects were fed a mixed natural diet providing 21% of energy as polyunsaturated and 11% as saturated fat (P/S2 ratio, 1.9) for 3 weeks, and one providing 5% of energy as polyunsaturated fat and 23% as saturated fat (P/S ratio, 0.2) for the next 3 weeks. The HAB-EGG group was fed the same diets in reverse order. The serum cholesterol concentrations were higher on the low P/S diet than on the high P/S diet (on average 23% in normal subjects and 16% in habitual egg eaters). The correlation coefficient between each subject's serum cholesterol response to fatty acids and his or her average response to dietary cholesterol in the dietary cholesterol experiments was 0.62 for the normal subjects (P less than 0.01) and 0.15 for the HAB-EGG group. We conclude that modest differences in responsiveness of serum cholesterol to dietary saturated fat do exist in humans, and that, in people of normal cholesterol intake, responsiveness to dietary cholesterol and to saturated fat tend to go together.
    Hyperresponsiveness of serum cholesterol to dietary cholesterol and dietary fatty acids in humans and rabbits.
    Glatz, J.F.C. ; Berns, M.A.M. ; Vries, J. de; Nobels, A. ; Beynen, A.C. ; Katan, M.B. - \ 1986
    European Journal of Clinical Investigation 16 (1986). - ISSN 0014-2972 - p. A54 - A54.
    Determinants of the increase of serum cholesterol with age: a longitudinal study.
    Berns, M.A.M. ; Katan, M.B. ; Vries, J.H.M. de - \ 1986
    European Journal of Clinical Investigation 16 (1986). - ISSN 0014-2972 - p. A53 - A53.
    Longitudinal study of the rise of serum cholesterol with age in young adults
    Berns, M.A.M. ; Katan, M.B. - \ 1985
    CVD epidemiology newsletter 38 (1985). - p. 63 - 63.
    Characteristics of human hypo- and hyper-responders to dietary cholesterol
    Katan, M.B. ; Beynen, A.C. ; Vries, J. de; Nobels, A. ; Berns, M.A.M. ; Glatz, J.F.C. - \ 1985
    Circulation 72 (1985)Suppl. III. - ISSN 0009-7322 - p. 118 - 118.
    Whole-body synthesis and fecal neutral steroid and bile acid excretion in man on diets high or low in linoleic acid
    Glatz, J.F.C. ; Berns, M.A.M. ; Katan, M.B. - \ 1985
    In: Cholest. metabol. in health and disease:studies in The Nethl / Beynen, A.C., Geelen, M.J.H., Katan, M.B., Schouten, J.A., Wageningen : Ponsen & Looijen - p. 120 - 125.
    Requirement of a dialyzable component from crude initiation factors for the translation of viral and eukaryotic messenger RNA
    Salden, M. ; Bisseling, T. ; Berns, A. ; Bloemendal, H. - \ 1975
    Biochemical and Biophysical Research Communications 65 (1975)1. - ISSN 0006-291X - p. 317 - 322.
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