Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Records 1 - 20 / 531

  • help
  • print

    Print search results

  • export
    A maximum of 250 titles can be exported. Please, refine your queryYou can also select and export up to 30 titles via your marked list.
  • alert
    We will mail you new results for this query: q=Bouwman
Check title to add to marked list
Zin in landbouw en zorg : diepere drijfveren van zorgboeren en hoe die tot uiting komen in hun praktijken
Westerink, Judith ; Elings, Marjolein ; Kloe-Bouwman, Nona De; Slikboer, Naomi - \ 2019
Wageningen : Wageningen University & Research, Wetenschapswinkel (Publicatie / Wageningen University & Research, Wetenschapswinkel 354) - ISBN 9789463951654 - 28
Extended indirect calorimetry with isotopic CO2 sensors allows real time quantification of substrate oxidation in mice: f1at oxidation levels depend on body fat mass
Schothorst, E.M. van; Fernández Calleja, J.M.S. ; Bouwman, L.M.S. ; Swarts, J.J.M. ; Oosting, Annemarie ; Keijer, J. - \ 2019
- 1 p.
Partial replacement of glucose by galactose in the post-weaning diet improves parameters of hepatic health
Bouwman, Lianne M.S. ; Swarts, Hans J.M. ; Fernández-Calleja, José M.S. ; Stelt, Inge van der; Schols, Henk ; Oosting, Annemarie ; Keijer, Jaap ; Schothorst, Evert M. van - \ 2019
Journal of Nutritional Biochemistry 73 (2019). - ISSN 0955-2863
Galactose - Inflammation - Liver health - Post-weaning diet - SAA3 - Transcriptomics

Replacing part of glucose with galactose in the post-weaning diet beneficially affects later life metabolic health in female mice. The liver is the main site of galactose metabolism, but the direct effects of this dietary intervention on the liver in the post-weaning period are not known. The aim of this study was to elucidate this. Weanling female mice (C57BL/6JRccHsd) were fed a starch containing diet with glucose (32 en%) monosaccharide (GLU), or a diet with glucose and galactose (1:1 both 16 en%) (GLU+GAL). Body weight, body composition, and food intake were determined weekly. After 3 weeks, mice were sacrificed, and serum and liver tissues were collected. Global hepatic mRNA expression was analyzed and hepatic triglyceride (TG) and glycogen contents were determined by enzymatic assays. Body weight and body composition were similar in both groups, despite higher food intake in mice on GLU+GAL diet. Hepatic TG content was lower in GLU+GAL-fed than GLU-fed females, while glycogen levels were unaffected. Analysis of global expression patterns of hepatic mRNA showed that mainly inflammation-related pathways were affected by the diet, which were predominantly downregulated in GLU+GAL-fed females compared to GLU-fed females. This reduction in inflammation in GLU+GAL-fed females was also reflected by decreased serum concentrations of acute phase protein Serum amyloid A 3. In conclusion, replacing part of glucose with galactose in the post-weaning diet reduces hepatic TG content and hepatic inflammation.

Integrated Analys of High-Fat Challenge-Induced Changes in Blood Cell Whole-Genome Gene Expression
Matualatupauw, Juri C. ; O'Grada, Colm ; Hughes, Maria F. ; Roche, Helen M. ; Afman, Lydia A. ; Bouwman, Jildau - \ 2019
Molecular Nutrition & Food Research 63 (2019)20. - ISSN 1613-4125
bioinformatics - high-fat challenge - microarrays - nutrigenomics - phenotypic flexibility - saturated fatty acids

Scope: Several studies have examined the whole-genome gene expression response in blood cells to high-fat challenges with differing results. The study aims to identify consistently up- or downregulated genes and pathways in response to a high-fat challenge using several integration methods. Methods and results: Three studies measuring the gene expression response to a high-fat challenge in white blood cells are evaluated for common trends using several integration methods. Overlap in differentially expressed genes between separate studies is examined, p-values of each separate study are combined, and data are analyzed as one merged dataset. Differentially expressed genes and pathways are compared between these methods. Selecting genes differentially expressed in the three separate studies result in 67 differentially expressed genes, primarily involved in circadian pathways. Using the Fishers p-value method and a merged dataset analysis, changes in 1097 and 1182 genes, respectively, are observed. The upregulated genes upon a high-fat challenge are related to inflammation, whereas downregulated genes are related to unfolded protein response, protein processing, cholesterol biosynthesis, and translation. Conclusion: A general gene expression response to a high-fat challenge is identified. Compared to separate analyses, integrated analysis provides added value for the discovery of a consistent gene expression response.

Effect on BMI of a multi-component treatment with E-modules for 3–8-year-old obese children
Hoek, Esther Van; Feskens, Edith J.M. ; Bouwman, Laura I. ; Verburgt, Wilma H. ; Jager, Wilco De; Schipper, Henk S. ; Vrijkotte, Tanja G.M. ; Janse, Arieke J. - \ 2019
Child and Adolescent Obesity 2 (2019)1. - ISSN 2574-254X - p. 79 - 95.
Introduction: Childhood obesity has serious health risks including the development of metabolic syndrome, cardiovascular disease and mortality later in life. The critical growth period from 3 to 7 years provides a window of opportunity for interventions. The goal of this study is to evaluate a one year, multidisciplinary, low-intensity treatment program for young obese children, complemented with web-based modules, called “AanTafel!”, on body composition, cardiometabolic risk profile, quality of life (HRQoL), eating behavior and physical activity.
Methods: In the pre-post-test design all measures were taken at baseline, 4 months, at the end of treatment and 3 years after baseline.
Results: Thirteen boys and 27 girls with median BMI z-score of, respectively, 4.2 and 3.3 aged 3 to 8 started “AanTafel!”. Eighty percent (n = 32) completed treatment. BMI z-score decreased with 0.45 (end of treatment) and sustained after 3 years. At the start, 16.7% of the children had all four components of metabolic syndrome which decreased to 0%. HDL cholesterol significantly increased. Concentrations of the markers IL18, e-selectin, and sICAM significantly decreased indicating a reduction of inflammation.
Conclusion: “AanTafel!” is effective in improving health of obese young children. The reduction of overweight is clinically relevant and sustained after 3 years
Non-invasive continuous real-time in vivo analysis of microbial hydrogen production shows adaptation to fermentable carbohydrates in mice
Schothorst, E.M. van; Fernández Calleja, J.M.S. ; Konstanti, Prokopis ; Swarts, J.J.M. ; Bouwman, L.M.S. ; Garcia-Campayo, Vicenta ; Billecke, Nils ; Oosting, Annemarie ; Smidt, H. - \ 2019
Genetic parameters for atypical reproductive patterns in dairy cows estimated from in-line milk progesterone profiles
Binsbergen, R. van; Bouwman, A.C. ; Veerkamp, R.F. - \ 2019
Journal of Dairy Science 102 (2019)12. - ISSN 0022-0302 - p. 11104 - 11115.
endocrine - fertility - genetic correlation - heritability

Our aim was to estimate genetic parameters of atypical reproductive patterns and estimate their genetic correlation with milk production and classical fertility traits for commercial dairy cows. In contrast with classical fertility traits, atypical reproductive patterns based on in-line milk progesterone profiles might have higher heritability and lower genetic correlation with milk production. We had in-line milk progesterone profiles available for 12,046 cycles in 4,170 lactations of 2,589 primiparous and multiparous cows (mainly Holstein Friesian) from 14 herds. Based on progesterone profiles, 5 types of atypical reproductive patterns in a lactation were defined: delayed ovulation types I and II, persistent corpus luteum types I and II, and late embryo mortality. These atypical patterns were detected in 14% (persistent corpus luteum type II) to 21% (persistent corpus luteum type I) of lactations. In 47% of lactations, at least 1 atypical pattern was detected. Threshold model heritabilities for atypical reproduction patterns ranged between 0.03 and 0.14 and for most traits were slightly higher compared with classical fertility traits. The genetic correlation between milk yield and calving interval was 0.56, whereas genetic correlations between milk yield and atypical reproductive patterns ranged between −0.02 and 0.33. Although most of these correlations between milk yield and atypical reproductive patterns are still unfavorable, they are lower compared with the correlations between classical fertility traits and milk yield. Therefore selection against atypical reproductive patterns may relax some constraints in current dairy breeding programs, to enhance genetic progress in both fertility and milk yield at a steady pace. However, as long as the target trait for fertility is calving interval, atypical reproductive patterns will not add additional value to the breeding goal in the near future due to the low number of available records.

Determinants of real-life behavioural interventions to stimulate more plant-based and less animal-based diets: A systematic review
Taufik, Danny ; Verain, Muriel C.D. ; Bouwman, Emily P. ; Reinders, Machiel J. - \ 2019
Trends in Food Science and Technology 93 (2019). - ISSN 0924-2244 - p. 281 - 303.

Background: Facilitating a transition to more plant-based and less animal-based diets would strongly alleviate the environmental impact of food, while plant-based diets can also decrease the health risks of excess meat consumption. So far, little is known about which underlying determinants can most effectively steer consumers to more healthy and/or sustainable food consumption. Gaining more knowledge about underlying determinants gives more insight into why certain interventions are effective or not in promoting healthy and/or sustainable food consumption among consumers. Scope and approach: In this systematic review real-life behavioural interventions are investigated that aim to promote more plant-based and/or less animal-based food consumption among consumers. The review focuses specifically on the interventions’ targeted determinants. In total, 48 articles (51 studies) are included in this review. Key findings and conclusions: The findings indicate that targeting individual determinants (such as increasing consumers’ level of self-regulation) or environmental determinants (such as modifying portion sizes) is relatively effective to promote more plant-based and less animal-based food consumption. Almost all included studies that aimed to increase plant-based food consumption focus on fruit and vegetables. This implies a need for future real-life intervention studies to focus on plant-based food consumption other than fruit and vegetables, such as legumes or whole grains. Also, relatively few real-life intervention studies have been conducted that focus on a decrease in animal-based food consumption, either separately or in combination with increasing plant-based food consumption. This review is registered with PROSPERO - CRD42019125314.

Post-weaning metabolic programming by dietary monosaccharides
Bouwman, Lianne M.S. - \ 2019
Wageningen University. Promotor(en): J. Keijer, co-promotor(en): E.M. van Schothorst; A. Oosting. - Wageningen : Wageningen University - ISBN 9789463950251 - 169
Reddingsoperatie voor zeldzame bosplant ‘knikkend nagelkruid’
Bouwman, Jaap ; Vergeer, P. - \ 2019
Nature Today
A Lowly Digestible-Starch Diet after Weaning Enhances Exogenous Glucose Oxidation Rate in Female, but Not in Male, Mice
Fernández-Calleja, José M.S. ; Bouwman, Lianne M.S. ; Swarts, Hans J.M. ; Billecke, Nils ; Oosting, Annemarie ; Keijer, Jaap ; Schothorst, Evert M. van - \ 2019
Nutrients 11 (2019)9. - ISSN 2072-6643
13C-starch - amylase - amylopectin - amylose - C57BL mice - glucose oxidation - glycaemic index - indirect calorimetry

Starches of low digestibility are associated with improved glucose metabolism. We hypothesise that a lowly digestible-starch diet (LDD) versus a highly digestible-starch diet (HDD) improves the capacity to oxidise starch, and that this is sex-dependent. Mice were fed a LDD or a HDD for 3 weeks directly after weaning. Body weight (BW), body composition (BC), and digestible energy intake (dEI) were determined weekly. At the end of the intervention period, whole-body energy expenditure (EE), respiratory exchange ratio (RER), hydrogen production, and the oxidation of an oral 13C-labelled starch bolus were measured by extended indirect calorimetry. Pancreatic amylase activity and total 13C hepatic enrichment were determined in females immediately before and 4 h after administration of the starch bolus. For both sexes, BW, BC, and basal EE and RER were not affected by the type of starch, but dEI and hydrogen production were increased by the LDD. Only in females, total carbohydrate oxidation and starch-derived glucose oxidation in response to the starch bolus were higher in LDD versus HDD mice; this was not accompanied by differences in amylase activity or hepatic partitioning of the 13C label. These results show that starch digestibility impacts glucose metabolism differently in females versus males.

Meetbaar maken van het effect van de Dutch Agri Food Week op waardering sector
Onwezen, M.C. ; Bouwman, Emily ; Reinders, M.J. ; Taufik, D. - \ 2019
Wageningen Economic Research - 4 p.
Nederlanders vrij positief over de landbouw- en voedselsector
Onwezen, M.C. ; Bouwman, Emily ; Reinders, M.J. ; Taufik, D. - \ 2019
Wageningen Economic Research - 5 p.
Prenatal infant feeding intentions and actual feeding practices during the first six months postpartum in rural Rwanda: a qualitative, longitudinal cohort study
Ahishakiye, J. ; Bouwman, L.I. ; Vaandrager, L. ; Koelen, M.A. ; Brouwer, I.D. - \ 2019
- 1 p.
Beneficial effect of personalized lifestyle advice compared to generic advice on wellbeing among Dutch seniors – An explorative study
Doets, Esmée L. ; Hoogh, Iris M. de; Holthuysen, Nancy ; Wopereis, Suzan ; Verain, Muriel C.D. ; Puttelaar, Jos van den; Hogenelst, Koen ; Boorsma, André ; Bouwman, Emily P. ; Timmer, Marielle ; Pasman, Wilrike J. ; Erk, Marjan van; Reinders, Machiel J. - \ 2019
Physiology and Behavior 210 (2019). - ISSN 0031-9384
Lifestyle behavior - Muscle health - Older adults - Personalized nutrition - Web-based feedback - Wellbeing

The aim of this explorative study is to evaluate whether personalized compared to generic lifestyle advice improves wellbeing in a senior population. We conducted a nine-week single-blind randomized controlled trial including 59 participants (age 67.7 ± 4.8 years) from Wageningen and its surrounding areas in the Netherlands. Three times during the intervention period, participants received either personalized advice (PA), or generic advice (GA) to improve lifestyle behavior. Personalization was based on metabolic health measures and dietary intake resulting in an advice that highlighted food groups and physical activity types for which behavior change was most urgent. Before and after the intervention period self-perceived health was evaluated as parameter of wellbeing using a self-perceived health score (single-item) and two questionnaires (Vita-16 and Short Form-12). Additionally, anthropometry and physical functioning (short physical performance battery, SPPB) were assessed. Overall scores for self-perceived health did not change over time in any group. Resilience and motivation (Vita-16) slightly improved only in the PA group, whilst mental health (SF-12) and energy (Vita-16) showed slight improvement only in the GA group. SPPB scores improved over time in both the PA and GA group. PA participants also showed a reduction in body fat percentage and hip circumference, whereas these parameters increased in the GA group Our findings suggest that although no clear effects on wellbeing were found, still, at least on the short term, personalized advice may evoke health benefits in a population of seniors as compared to generic advice.

Extended indirect calorimetry with isotopic CO2 sensors for prolonged and continuous quantification of exogenous vs. total substrate oxidation in mice
Fernández-Calleja, José M.S. ; Bouwman, Lianne M.S. ; Swarts, Hans J.M. ; Oosting, Annemarie ; Keijer, Jaap ; Schothorst, Evert M. van - \ 2019
Scientific Reports 9 (2019). - ISSN 2045-2322

Indirect calorimetry (InCa) estimates whole-body energy expenditure and total substrate oxidation based on O2 consumption and CO2 production, but does not allow for the quantification of oxidation of exogenous substrates with time. To achieve this, we incorporated 13CO2 and 12CO2 gas sensors into a commercial InCa system and aimed to demonstrate their performance and added value. As a performance indicator, we showed the discriminative oscillations in 13CO2 enrichment associated with food intake in mice fed diets containing naturally low (wheat) vs high (maize) 13C enrichment. To demonstrate the physiological value, we quantified exogenous vs total carbohydrate and fat oxidation continuously, in real time in mice varying in fat mass. Diet-induced obese mice were fed a single liquid mixed meal containing 13C-isotopic tracers of glucose or palmitate. Over 13 h, ~70% glucose and ~48% palmitate ingested were oxidised. Exogenous palmitate oxidation depended on body fat mass, which was not the case for exogenous glucose oxidation. We conclude that extending an InCa system with 13CO2 and 12CO2 sensors provides an accessible and powerful technique for real-time continuous quantification of exogenous and whole-body substrate oxidation in mouse models of human metabolic physiology.

Fibre formation in calcium caseinate influenced by solvent isotope effect and drying method – A neutron spectroscopy study
Tian, Bei ; Garcia Sakai, Victoria ; Pappas, Catherine ; Goot, Atze Jan van der; Bouwman, W.G. - \ 2019
Chemical Engineering Science 207 (2019). - ISSN 0009-2509 - p. 1270 - 1277.
Calcium caseinate - Drying method - Fibre formation - Neutron spectroscopy - Protein dynamics - Solvent isotope effect

We present an investigation of the dynamics of calcium caseinate as a function of hydration, solvent isotope (H2O and D2O) and drying methods (roller drying and spray drying), using quasi-elastic neutron scattering (QENS). These factors are key to the formation of fibres in this material which makes it a potential candidate as a next-generation meat analogue. Using a phenomenological model, we find that the relaxation times of the dry spray dried powder decrease with increasing temperatures, while they do not change for the roller dried powder. The spectra of the hydrated samples reveal two independent picosecond processes, both reflecting localized re-orientational motions. We hypothesize that the faster motion is due to the external protein groups that are hydrophilic and the slower motion is due to the internal groups that are hydrophobic. The solvent effect of D2O is not limited to the external groups but prevails to the internal groups where less protons are mobile compared to the H2O hydrated samples. Higher temperatures narrow the number difference in mobile protons, possibly by altering the weak interactions inside the protein aggregates. These findings suggest that a harsh and longer drying process contributes to less active protein side-groups and highlight the hydrophobic effect of D2O on the fibre formation in calcium caseinate.

Replacing Part of Glucose with Galactose in the Postweaning Diet Protects Female But Not Male Mice from High-Fat Diet-Induced Adiposity in Later Life
Bouwman, Lianne M.S. ; Fernández-Calleja, José M.S. ; Stelt, Inge van der; Oosting, Annemarie ; Keijer, Jaap ; Schothorst, Evert M. van - \ 2019
The Journal of Nutrition 149 (2019)7. - ISSN 0022-3166 - p. 1140 - 1148.
adipose tissue - galactose - insulin signaling - lactose - postweaning - programming

BACKGROUND: Duration of breastfeeding is positively associated with decreased adiposity and increased metabolic health in later life, which might be related to galactose. OBJECTIVE: The aim of this study was to investigate if partial replacement of glucose with galactose in the postweaning diet had a metabolic programming effect. METHODS: Male and female mice (C57BL/6JRccHsd) received an isocaloric diet (16 energy% fat; 64 energy% carbohydrates; 20 energy% protein) with either glucose (32 energy%) (GLU) or glucose + galactose (GLU + GAL, 16 energy% each) for 3 wk postweaning. Afterwards, all mice were switched to the same 40 energy% high-fat diet (HFD) for 9 wk to evaluate potential programming effects in an obesogenic environment. Data were analyzed within sex. RESULTS: Female body weight (-14%) and fat mass (-47%) were significantly lower at the end of the HFD period (both P < 0.001) among those fed GLU + GAL than among those fed GLU; effects in males were in line with these findings but nonsignificant. Food intake was affected in GLU + GAL-fed females (+8% on postweaning diet, -9% on HFD) compared with GLU-fed females, but not for hypothalamic transcript levels at endpoint. Also, in GLU + GAL-fed females, serum insulin concentrations (-48%, P < 0.05) and the associated homeostasis model assessment of insulin resistance (HOMA-IR) were significantly lower ( P < 0.05) at endpoint, but there were no changes in pancreas morphology. In GLU + GAL-fed females, expression of insulin receptor substrate 2 (Irs2) (-27%, P < 0.01 ; -44%, P < 0.001) and the adipocyte size markers leptin (Lep) (-40%, P < 0.05; -63% , P < 0.05) and mesoderm-specific transcript homolog protein (Mest) (-80%, P < 0.05; -72%, P < 0.05) was lower in gonadal and subcutaneous white adipose tissue (WAT), respectively. Expression of insulin receptor substrate1 (Irs1) (-24%, P < 0.05) was only lower in subcutaneous WAT in GLU + GAL-fed females. CONCLUSIONS: Partial replacement of glucose with galactose, resulting in a 1:1 ratio mimicking lactose, in a 3-wk postweaning diet lowered body weight, adiposity, HOMA-IR, and expression of WAT insulin signaling in HFD-challenged female mice in later life. This suggests that prolonged galactose intake may improve metabolic and overall health in later life.

Addendum: The FAIR Guiding Principles for scientific data management and stewardship
Wilkinson, Mark D. ; Dumontier, Michel ; Aalbersberg, Ijsbrand Jan ; Appleton, Gabrielle ; Axton, Myles ; Baak, Arie ; Blomberg, Niklas ; Boiten, Jan Willem ; Silva Santos, Luiz Bonino Da; Bourne, Philip E. ; Bouwman, Jildau ; Brookes, Anthony J. ; Clark, Tim ; Crosas, Mercè ; Dillo, Ingrid ; Dumon, Olivier ; Edmunds, Scott ; Evelo, Chris T. ; Finkers, Richard ; Gonzalez-Beltran, Alejandra ; Gray, Alasdair J.G. ; Groth, Paul ; Goble, Carole ; Grethe, Jeffrey S. ; Heringa, Jaap ; Hoen, Peter A.C. 't; Hooft, Rob ; Kuhn, Tobias ; Kok, Ruben ; Kok, Joost ; Lusher, Scott J. ; Martone, Maryann E. ; Mons, Albert ; Packer, Abel L. ; Persson, Bengt ; Rocca-Serra, Philippe ; Roos, Marco ; Schaik, Rene van; Sansone, Susanna Assunta ; Schultes, Erik ; Sengstag, Thierry ; Slater, Ted ; Strawn, George ; Swertz, Morris A. ; Thompson, Mark ; Lei, Johan van der; Mulligen, Erik van; Velterop, Jan ; Waagmeester, Andra ; Wittenburg, Peter ; Wolstencroft, Katherine ; Zhao, Jun ; Mons, Barend - \ 2019
Scientific Data 6 (2019). - ISSN 2052-4463

Overview of existing knowledge concerning food behaviour interventions out-of-home, in the working environment and in online settings : a literature quick scan -WP1 -Food, Value, Impact
Reinders, Machiel ; Bouwman, Emily ; Taufik, Danny - \ 2019
Wageningen : Wageningen Economic Research - 97
In this deliverable of the PPS project Food, Value, Impact an overview is made of scientific food behaviour intervention studies with a focus on three real-life settings that have a central role in this project, namely out-of-home, the working environment and online(i.e., web-based food behaviour interventions through websites or apps). This deliverable provides insight into which type of behavioural interventions have been tested and are particularly effective in stimulating healthy and/or sustainable food choices in each of these three settings. The overview is based on 89 studies in total (out-of-home: 24; working environment: 33; online: 32), that were found by doing a literature search in the database Web of Science. Results show that in the settings out-of-homeand working environment most interventions tested a type of nudging strategy to stimulate healthy and/or sustainable food choices, whereas in the setting onlinemost interventions tested forms of information and/or education in order to entice consumers to make more healthy and/or sustainable food choices. Moreover, most studies focus on interventions related to healthy food choices. The large majority of the interventions that were included in the quick scan were successful in stimulating the targeted behaviour.
This overview can be helpful for researchers who are involved in the project Food, Value, Impact or who are interested or want to develop an intervention in one of these settings (e.g. the use cases). Note that the studies that are described in this deliverable are based on a quick scan of the literature and cannot be labelled as a systematic review. The articles described depend on the search criteria that were set for the literature search. Therefore it is possible that some relevant studies might be missing. Nevertheless, this literature quick scan gives an indication of which intervention components are particularly effective in stimulating healthy and/or sustainable food choicesineach of the three settings.
Check title to add to marked list
<< previous | next >>

Show 20 50 100 records per page

Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.