Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Weele, C. van der; Driessen, C.P.G. - \ 2014
    In: Het kweekvleeskookboek / Grievink, H.J., van Mensvoort, K., Amsterdam : BIS Publishers - ISBN 9789063693589 - p. 79 - 89.
    In vitro meat as animal liberation
    Weele, C. Van der; Driessen, C.P.G. - \ 2014
    In: The In Vitro Meat Cookbook / van Mensvoort, K., Grievink, H.J., BIS Publishers - ISBN 9789063693589 - p. 76 - 88.
    Characterization of Romboutsia ilealis gen. nov., sp. nov., isolated from the gastro-intestinal tract of a rat and proposal for the reclassification of five closely related members of the genus Clostridium into the genera Romboutsia gen. nov., Intestinibacter gen. nov., Terrisporobacter gen. nov. and Asaccharospora gen. nov.
    Gerritsen, J. ; Fuentes Enriquez de Salamanca, S. ; Grievink, W. ; Niftrik, L. van; Tindall, B.J. ; Timmerman, H.M. ; Rijkers, G.T. ; Smidt, H. - \ 2014
    International Journal of Systematic and Evolutionary Microbiology 64 (2014)Pt. 5. - ISSN 1466-5026 - p. 1600 - 1616.
    ribosomal-rna genes - acid methyl-esters - lipid-composition - deoxyribonucleic-acid - electron microscopy - renaturation rates - dna hybridization - polar lipids - bacteria - chromatography
    A Gram-positive staining, rod-shaped, non-motile, spore-forming obligately anaerobic bacterium, designated CRIBT, was isolated from the gastro-intestinal tract of a rat and characterized. The major cellular fatty acids of strain CRIBT were saturated and unsaturated straight chain C12-C19 fatty acids, with C16:0 being the predominant fatty acid. The polar lipid profile comprised six glycolipids, four phospholipids and one lipid that did not stain with any of the specific spray reagents used. The only quinone was MK-6. The predominating cell wall sugars were glucose and galactose. The peptidoglycan type of strain CRIBT was A1d lanthionine-direct. The genomic DNA G+C content of strain CRIBT was 28.1 mol %. On the basis of 16S rRNA gene sequence similarity, strain CRIBT was most closely related to a number of Clostridium species, including C. lituseburense (97.2 %), C. glycolicum (96.2 %), C. mayombei (96.2 %), C. bartlettii (96.0 %) and C. irregulare (95.5 %). All these species show very low 16S rRNA gene sequence similarity (
    Persistent mental health disturbances during the 10 years after a disaster: Four-wave longitudinal comparative study
    Velden, P.G. ; Wong, A. ; Boshuizen, H.C. ; Grievink, L. - \ 2013
    Psychiatry and Clinical Neurosciences 67 (2013)2. - ISSN 1323-1316 - p. 110 - 118.
    posttraumatic-stress-disorder - earthquake survivors - trajectories - resilience - impact
    Aim Although some studies have examined the long-term effects of disasters, very little is known about severe persistent symptoms following disasters. The aim of the present study was to examine persistent mental health problems and to what extent disaster exposure predicts long-term persistent disturbances. Methods Following a major disaster, a four-wave study was conducted (surveys 2–3¿weeks, 18¿months, 4¿years and 10¿years after the event) that examined severe post-traumatic stress disorder (PTSD) symptomatology (Impact of Event Scale), anxiety and depression symptoms and sleeping problems (Symptom Check List-90-R), and use of physician-prescribed tranquilizers. Participants were affected adult Dutch native residents (n¿=¿1083). At wave 2 and 3, a control group participated (n¿=¿694). At wave 1, severity of disaster exposure was examined. Multiple imputation was used to target the problem of missing data across surveys due to non-response such as in the fourth wave (61%). Results In total, 6.7% (95% confidence interval [CI]: 5.1–8.2) developed persistent PTSD symptoms during the 10¿years after the event. For anxiety, depression, sleeping problems these prevalences were 3.8% (95%CI: 2.7–5.0), 6.2% (95%CI: 4.7–7.6) and 4.8% (95%CI: 3.5–6.1) respectively. In total 1.3% (95%CI: 0.6–2.0) used tranquilizers at all waves. Approximately one out of 10 with severe symptoms 2–3¿weeks after the event, developed persistent symptoms. Even in the long term, affected residents compared to controls had more often chronic anxiety symptoms and sleeping problems. High disaster exposure independently predicted persistent PTSD symptoms (adjusted odds ratio [adj. OR], 4.20; 95%CI: 2.02–8.74, P¿
    Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster -- a longitudinal study
    Berg, B. van den; Wong, A. ; Velden, P.G. ; Boshuizen, H.C. ; Grievink, L. - \ 2012
    BMC Psychiatry 12 (2012). - ISSN 1471-244X - 26 p.
    posttraumatic-stress-disorder - symptoms - adults - metaanalysis - responses - services - impact - ptsd - bias
    BackgroundDisaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term.
    Voedselbalans 2011 : Dl. 3 Aanbieders
    Bartels, J. ; Reinders, M.J. ; Winter, M.A. de; Grievink, J.W. - \ 2011
    Den Haag : LEI Wageningen UR - ISBN 9789086155101 - 74
    voedselindustrie - voedselconsumptie - duurzaamheid (sustainability) - voedingsmiddelen - duurzame ontwikkeling - consumenten - food industry - food consumption - sustainability - foods - sustainable development - consumers
    In dit achtergrondrapport "Voedselbalans: Aanbieders" staat een uitgebreide beschrijving van het onderzoek dat is uitgevoerd onder bedrijven uit de retail-, Out-Of-Home (OOH) en Voedings- en genotsmiddelenindustrie/ fabrikanten (VGI).
    Voedselbalans 2011 : Dl. 1 Dynamiek in duurzaam
    Backus, G.B.C. ; Meeusen, M.J.G. ; Dagevos, H. ; Riet, J.P. van 't; Bartels, J. ; Onwezen, M.C. ; Reinders, M.J. ; Winter, M.A. de; Grievink, J.W. - \ 2011
    Den Haag : LEI Wageningen UR - ISBN 9789086155088 - 56
    consumentengedrag - voedselconsumptie - duurzaamheid (sustainability) - duurzame ontwikkeling - voedingsmiddelen - consumer behaviour - food consumption - sustainability - sustainable development - foods
    De Voedselbalans werkt met een model waarin het gedrag van consumenten en aanbieders wordt beschreven. Daarbij gaat het om wetenschappelijk onderbouwde factoren. De resultaten van het onderzoek worden vertaald in handelingsperspectieven.
    A case-control study of plasma antioxidant (pro-)vitamins in relation to respiratory symptoms in non-smokers
    Grievink, L. ; Smit, H.A. ; Veer, P. van 't; Brunekreef, B. ; Kromhout, D. - \ 2000
    Epidemiology 11 (2000). - ISSN 1044-3983 - p. 59 - 63.
    The aim of this study was to investigate the relations between plasma levels of antioxidants, [beta]-carotene and [alpha]-tocopherol, and chronic respiratory symptoms in Dutch adults who never smoked or were long-term former smokers. Cases (who reported one or more respiratory symptoms) and controls were selected from a population-based cross-sectional study. Plasma concentrations of antioxidants were determined in 491 cases and 496 controls. ORs for the presence of chronic respiratory symptoms were estimated for quintiles of plasma antioxidant concentration after adjustment for age, gender, and body mass index. The OR of respiratory symptoms in all but the highest quintile of plasma [beta]-carotene decreased and were slightly below one. We saw no meaningful relation with plasma [alpha]-tocopherol.
    Serum carotenoids, alpha-tocopherol, and lung function among Dutch elderly
    Grievink, L. ; Waart, F.G. de; Schouten, E.G. ; Kok, F.J. - \ 2000
    American Journal of Respiratory and Critical Care Medicine 161 (2000). - ISSN 1073-449X - p. 790 - 795.
    Antioxidant vitamins (provitamins) may protect against loss of lung function over time. We studied the association between serum carotenoids (-carotene, -carotene, lycopene, -cryptoxanthin, zeaxanthin, and lutein), -tocopherol, and lung function among noninstitutionalized Dutch elderly age 65 to 85 yr (n = 528). Multiple linear regression analysis was performed with FEV1 or FVC as dependent variables and serum levels of antioxidants in quintiles as independent variables. We adjusted for age, gender, height, and pack-years of smoking. Subjects in the fifth quintile of serum -carotene had a 195 ml (95␌onfidence interval [95␌I]: 40 to 351 ml) higher and those in the fifth quintile of -carotene had a 257 ml (95␌I: 99 to 414 ml) higher FEV1 compared with subjects in the first quintile of these carotenoids. Significant (p < 0.05) positive trends were observed between -carotene, -carotene, lycopene, and FEV1 and between -carotene, -carotene, and FVC. Subjects in the highest quintile of the other carotenoids or -tocopherol did not have significantly higher FEV1 or FVC compared with subjects in the first quintile of these antioxidants. In conclusion, this study shows that from the six major serum carotenoids and -tocopherol studied, particularly -carotene, -carotene, and lycopene were positively associated with lung function in the elderly and may be considered as candidates for further investigations. Grievink L, de Waart FG, Schouten EG, Kok FJ. Serum carotenoids, -tocopherol, and lung function among Dutch elderly.
    Dietary influences on chronic obstructive lung disease and asthma : a review of the epidemiological evidence
    Smit, H.A. ; Grievink, L. ; Tabak, C. - \ 1999
    Proceedings of the Nutrition Society 58 (1999). - ISSN 0029-6651 - p. 309 - 319.
    Modulation of the acute respiratory effects of winter air pollution by serum and dietary antioxidants : a panel study
    Grievink, L. ; Zee, S.C. van der; Hoek, G. ; Boezen, H.M. ; Veer, P. van 't; Brunekreef, B. - \ 1999
    European Respiratory Journal 13 (1999). - ISSN 0903-1936 - p. 1439 - 1446.
    Plasma concentrations of the antioxidants beta-carotene and alpha-tocopherol in relation to lung function
    Grievink, L. ; Smit, H.A. ; Veer, P. van 't; Brunekreef, B. ; Kromhout, D. - \ 1999
    European Journal of Clinical Nutrition 52 (1999). - ISSN 0954-3007 - p. 813 - 817.
    Double-blind intervention trial on modulation of ozone effects on pulmonary function by antioxidant supplements
    Grievink, L. ; Zijlstra, A.G. ; Xiaodong, K. ; Brunekreef, B. - \ 1999
    American Journal of Epidemiology 149 (1999). - ISSN 0002-9262 - p. 306 - 314.
    Dietary intake of antioxidant (pro)-vitamins, respiratory symptoms and pulmonary function: the MORGEN study.
    Grievink, L. ; Smit, H.A. ; Ocke, M.C. ; Veer, P. van 't; Kromhout, D. - \ 1998
    Thorax 53 (1998). - ISSN 0040-6376 - p. 166 - 171.
    Antioxidants and air pollution in relation to indicators of asthma and COPD
    Grievink, L. - \ 1998
    Agricultural University. Promotor(en): B. Brunekreef; D. Kromhout; H.A. Smit. - S.l. : Grievink - ISBN 9789054859499 - 134
    antioxidanten - luchtverontreiniging - astma - ademhalingsziekten - antioxidants - air pollution - asthma - respiratory diseases

    Two main research questions were specified in this thesis. First, whether acute respiratory effects of air pollution can be modulated by antioxidants. Second, whether dietary or plasma antioxidants were associated with indicators of asthma and COPD.

    Two intervention studies investigated a possible modulation of the acute respiratory effects of ozone by antioxidant supplementation. In addition a panel study examined a possible modulation of the acute respiratory effects of winter air pollution by antioxidants in diet and serum.

    The first intervention study in 1994 was a pilot study among 26 cyclists who performed lung function measurements (192 observations) before and after exercise. Half of the group was randomly assigned to the supplementation group and were given a daily antioxidant supplementation of vitamins C, E andβ-carotene. The control group did not receive a placebo. We repeated the study in the summer of 1996 with a similar design but this time the study was placebo-controlled. In this study, 38 subjects (380 lung function measurements) participated until the end of the study and the antioxidant supplementation consisted of a cocktail of vitamins C and E.

    Both intervention studies suggest that there was an effect of ozone on FEV 1 and FVC in the control group. There was no change in lung function when ozone levels were high in the supplementation group. The difference in ozone effect between the groups for both studies was statistically significant for FEV 1 and FVC. In the analysis of the panel study, we included only subjects with chronic respiratory symptoms because these subjects showed clear acute respiratory effects of air pollution. The results suggest that subjects with low levels of plasmaβ-carotene showed an effect of air pollution on large PEF decrements, in particular, for PM10 and black smoke, whereas subjects with high levels of plasmaβ-carotene did not show an effect of air pollution. No difference in acute respiratory effects of air pollution was observed for a high versus a low dietary intake of vitamin C, E andβ-carotene or for plasmaα-tocopherol.

    The second research question was investigated within the MORGEN study. This study is a cross-sectional investigation on the prevalence of risk factors for chronic diseases using self-administered questionnaires and a physical examination in a randomly selected sample of the Dutch population.

    First, we examined the relations between dietary antioxidants (vitamins C, E andβ-carotene) and the prevalence of a number of respiratory symptoms and lung function in a population based sample of 6,555 adults. Our results suggested that a high dietary vitamin C andβ-carotene intake was associated with a higher FEV 1 and FVC. Dietary vitamin E was not associated with lung function. None of the dietary antioxidants were consistently associated with the prevalence of a number of respiratory symptoms.

    Second, we studied the relation between plasma levels ofβ-carotene orα-tocopherol and respiratory symptoms in a case-control sample of never and long-term former smokers. Our results suggested that cases (subjects with one or more chronic respiratory symptoms; n=491) tended to have lower plasmaβ-carotene levels than controls (n=496). Plasmaα-tocopherol was not associated with asthma and chronic bronchitis symptoms but was positively associated with dyspnea. This adverse association of plasmaα-tocopherol could not be explained by adjustment for cardiovascular risk factors and remains puzzling. Third, we evaluated the relation between plasma antioxidants (β-carotene andα-tocopherol) and lung function in a random sample (n=367) of the MORGEN study. We found that subjects with a high plasmaβ-carotene concentration tended to have a higher FVC and FEV 1 than subjects with a low plasmaβ-carotene concentration but this was not statistically significant for FEV 1 . Plasmaα-tocopherol was not associated with lung function.

    Acute effects of ozone on pulmonary function of cyclists receiving antioxidant supplements.
    Grievink, L. ; Jansen, S.M.A. ; Veer, P. van 't; Brunekreef, B. - \ 1998
    Occupational and Environmental Medicine 55 (1998). - ISSN 1351-0711 - p. 13 - 17.
    Antioxidant (pro-)vitamines en longfunctie.
    Grievink, L. ; Smit, H.A. ; Kromhout, D. - \ 1998
    Tijdschrift voor Gezondheidswetenschappen 76 (1998). - ISSN 1388-7491 - p. 27 - 27.
    Antioxidant supplementation and respiratory functions among workers exposed to high levels of ozone.
    Romieu, I. ; Meneses, F. ; Ramirez, M. ; Ruiz, S. ; Perez Padilla, R. ; Sienra, J.J. ; Gerber, M. ; Grievink, L. ; Dekker, R. ; Walda, I. ; Brunekreef, B. - \ 1998
    American Journal of Respiratory and Critical Care Medicine 158 (1998). - ISSN 1073-449X - p. 226 - 232.
    Inname van antioxidant (pro)-vitamines en chronische respiratoire symptomen: morgen-project.
    Grievink, L. ; Smit, H.A. ; Veer, P. van 't; Kromhout, D. - \ 1997
    Pulmonair 4 (1997). - ISSN 1380-6505 - p. 6 - 6.
    Is the effect of the intake of vitamin C on lung function confounded by the intake of beta-carotene.
    Grievink, L. ; Smit, H.A. - \ 1997
    European Respiratory Journal 10 (1997)suppl 25. - ISSN 0903-1936 - p. 308S - 308S.
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