Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

    Records 1 - 20 / 573

    • help
    • print

      Print search results

    • export
      A maximum of 250 titles can be exported. Please, refine your queryYou can also select and export up to 30 titles via your marked list.
    Check title to add to marked list
    Opportunities for seaweed biorefinery
    Lange, Lene ; Grandorf Bak, Urd ; Cole Brandstrup Hansen, Steffen ; Gregersen, Olavur ; Harmsen, Paulien ; Nordberg Karlsson, Eva ; Meyer, Anne ; Mikkelsen, Maria D. ; Broek, Ben van den; Óli Hreggviðsson, Guðmundur - \ 2020
    In: Sustainable Seaweed Technologies / Dolores Torres, M., Kraan, S., Dominguez, H., Elsevier (Advances in Green Chemistry ) - ISBN 9780128179437 - p. 3 - 31.
    This introductory chapter provides an overview of seaweed biorefinery opportunities, providing basis for multiple value chains, contributing to nutrition and health of a growing global population, to local job generation and development, to ecosystem services, and not the least to climate change mitigation and adaptation. A unique and rich diversity of the seaweed components provides the basis for the broad spectrum of value-chains described here. Red, brown, and green seaweeds are phylogenetically very different and this is reflected in their differences in growth, structure, and biochemical composition. Stable supply and high quality of feedstock are essential for unlocking the value-adding potential of seaweeds. A special focus of the chapter is to provide an overview of the range of different methods of seaweed production (through cultivation or from natural growth, collected or cut at the shore). Furthermore, the results of dedicated efforts to develop new deep-sea cultivation technologies of brown seaweed are highlighted. The chapter has a dual message with regard to seaweed processing: the need to develop more environmentally benign biological processing (to replace chemical processing); the advantage (regarding resource efficiency) and opportunities (social and economic) of designing seaweed biorefineries according to the cascading principle. Making optimized use of all valuable components of seaweed biomass, cascading from high-value products, such as skin care, health-promoting food and feed supplements and functional food ingredients; to lower-value products, such as plant stimulants, soil improvers, and bioenergy. Lastly, this introductory chapter provides global perspectives for future development of sustainable seaweed utilization, contributing to the UN-SDGs, providing livelihood and health for more.
    Bioraffinage Innovatie Cluster Regio Gelderland (BIC-Gelderland) : Valorisatie lignocellulose-rijke biomassa Fase 1: Technische haalbaarheidsstudie
    Ankone, Bouke ; Jacobs, Anneleen ; Brinkmann, Arjen ; Adriaanse, Michiel ; Bousios, Spyros ; Hooimeijer, Arie ; Jolink, Raymond ; Kooij, Aldert van der; Koene, Joep ; Boer, Louis de; Dijk, Lex van; Beekhuis, Harm ; Budding, Arjan ; Harmsen, Paulien ; Dam, Jan van; Annevelink, Bert ; Keijsers, Edwin ; Ree, René van - \ 2020
    Wageningen : Food & Biobased Research Wageningen UR - 43
    Multimeric single-domain antibody complexes protect against bunyavirus infections
    Wichgers Schreur, Paul J. ; Water, Sandra van de; Harmsen, Michiel ; Bermúdez-Méndez, Erick ; Drabek, Dubravka ; Grosveld, Frank ; Wernike, Kerstin ; Beer, Martin ; Aebischer, Andrea ; Daramola, Olalekan ; Conde, Sara Rodriguez ; Brennan, Karen ; Kozub, Dorota ; Kristiansen, Maiken Søndergaard ; Mistry, Kieran K. ; Deng, Ziyan ; Hellert, Jan ; Guardado-Calvo, Pablo ; Rey, Félix A. ; Keulen, Lucien van; Kortekaas, Jeroen - \ 2020
    eLife 9 (2020). - ISSN 2050-084X

    The World Health Organization has included three bunyaviruses posing an increasing threat to human health on the Blueprint list of viruses likely to cause major epidemics and for which no, or insufficient countermeasures exist. Here, we describe a broadly applicable strategy, based on llama-derived single-domain antibodies (VHHs), for the development of bunyavirus biotherapeutics. The method was validated using the zoonotic Rift Valley fever virus (RVFV) and Schmallenberg virus (SBV), an emerging pathogen of ruminants, as model pathogens. VHH building blocks were assembled into highly potent neutralizing complexes using bacterial superglue technology. The multimeric complexes were shown to reduce and prevent virus-induced morbidity and mortality in mice upon prophylactic administration. Bispecific molecules engineered to present two different VHHs fused to an Fc domain were further shown to be effective upon therapeutic administration. The presented VHH-based technology holds great promise for the development of bunyavirus antiviral therapies.

    Taking stock of national climate policies to evaluate implementation of the Paris Agreement
    Roelfsema, Mark ; Soest, Heleen L. van; Harmsen, Mathijs ; Vuuren, Detlef P. van; Bertram, Christoph ; Elzen, Michel den; Höhne, Niklas ; Iacobuta, Gabriela ; Krey, Volker ; Kriegler, Elmar ; Luderer, Gunnar ; Riahi, Keywan ; Ueckerdt, Falko ; Després, Jacques ; Drouet, Laurent ; Emmerling, Johannes ; Frank, Stefan ; Fricko, Oliver ; Gidden, Matthew ; Humpenöder, Florian ; Huppmann, Daniel ; Fujimori, Shinichiro ; Fragkiadakis, Kostas ; Gi, Keii ; Keramidas, Kimon ; Köberle, Alexandre C. ; Aleluia Reis, Lara ; Rochedo, Pedro ; Schaeffer, Roberto ; Oshiro, Ken ; Vrontisi, Zoi ; Chen, Wenying ; Iyer, Gokul C. ; Edmonds, Jae ; Kannavou, Maria ; Jiang, Kejun ; Mathur, Ritu ; Safonov, George ; Vishwanathan, Saritha Sudharmma - \ 2020
    Nature Communications 11 (2020)1. - ISSN 2041-1723

    Many countries have implemented national climate policies to accomplish pledged Nationally Determined Contributions and to contribute to the temperature objectives of the Paris Agreement on climate change. In 2023, the global stocktake will assess the combined effort of countries. Here, based on a public policy database and a multi-model scenario analysis, we show that implementation of current policies leaves a median emission gap of 22.4 to 28.2 GtCO2eq by 2030 with the optimal pathways to implement the well below 2 °C and 1.5 °C Paris goals. If Nationally Determined Contributions would be fully implemented, this gap would be reduced by a third. Interestingly, the countries evaluated were found to not achieve their pledged contributions with implemented policies (implementation gap), or to have an ambition gap with optimal pathways towards well below 2 °C. This shows that all countries would need to accelerate the implementation of policies for renewable technologies, while efficiency improvements are especially important in emerging countries and fossil-fuel-dependent countries.

    Hoge Veluwe soil gets fertilizer
    Harmsen, Sylvana - \ 2020
    Textiles for circular fashion : Part 1: Fibre resources and recycling options
    Harmsen, Paulien ; Bos, Harriëtte - \ 2020
    Wageningen : Wageningen Food & Biobased Research (Groene grondstoffen ) - ISBN 9789463953399 - 100
    Circulaire systemen
    Bos, Harriëtte ; Groenestijn, John van; Harmsen, Paulien ; Hugenholtz, Jeroen ; Appelmans, Wilfred ; Jetten, Jan ; Bussmann, Pauil ; Bon, Jeroen van; Burgering, Maurits ; Verdoes, Nico ; Groenestein, Karin ; Duinkerken, Gert van; Fels-Klerx, Ine van der; Schans, Milou van de; Gerrits, Elise ; Schoumans, Oscar ; Haas, Wim de; Regelink, Inge ; Stuiver, Marian ; Bakker, Sjaak ; Dijk, Wim van; Visser, Saskia - \ 2019
    Wageningen : Wageningen University & Research - 41
    Biomassa voor de circulaire economie : Alles wat je wilde weten over biomassa maar nooit durfde te vragen
    Groenestijn, Johan van; Harmsen, Paulien ; Bos, Harriëtte - \ 2019
    Wageningen : Wageningen Food & Biobased Research (Groene grondstoffen 23) - ISBN 9789463439541 - 100
    biobased economy - biomassa - bio-energie - verwerking - chemische technologie - diervoeding - compost - biobased economy - biomass - bioenergy - processing - chemical technology - animal nutrition - composts
    Nederland en de meeste andere landen willen het gebruik van koolstofhoudende fossiele grondstoffen zoals aardolie, steenkool en aardgas verminderen. De twee belangrijkste motivaties hiervoor zijn de klimaatproblematiek en de eindigheid van de voorraden van deze grondstoffen. Het gebruik van fossiele brandstoffen en kunststoffen die gemaakt zijn uit fossiele grondstoffen verandert het klimaat doordat na verbranding of na biologische afbraak koolstofdioxide vrijkomt dat zich ophoopt in de atmosfeer en daar het broeikaseffect versterkt. Een atmosfeer met een verhoogd gehalte aan koolstofdioxide houdt de warmte beter vast en verhoogt daardoor de temperatuur van de atmosfeer, zoals een broeikas dat doet. Sinds het jaar 1750, het begin van de industriële revolutie, is de koolstofdioxideconcentratie met 48% toegenomen en veel klimatologen gaan er vanuit dat dat de hoofdoorzaak is van de eveneens toegenomen temperatuur op aarde. Volgens hen zal deze temperatuursverhoging leiden tot een stijging van de zeespiegel en extremer weer (stormen, droogte, overstromingen).
    Biomass for the Circular Economy : Everything you wanted to know about biomass but were afraid to ask
    Groenestijn, Johan van; Harmsen, Paulien ; Bos, Harriëtte - \ 2019
    Wageningen : Wageningen Food & Biobased Research (Groene grondstoffen 23) - ISBN 9789463951692 - 100
    biobased economy - biomassa - nederland - bio-energie - beschikbaarheid - biomassaconversie - technology assessment - biobased economy - biomass - netherlands - bioenergy - availability - biomass conversion - technology assessment
    We have compiled this booklet with the aim of providing an overview and, where possible, guidelines for policy and entrepreneurship. It offers an overview of the types of biomass and biomass availability on the scale of the Netherlands, Europe and the world, and the available technologies for converting biomass into a range of useful products.
    Certainties and uncertainties in accessing toxicity of non-extractable residues (NER) in soil
    Harmsen, Joop ; Hennecke, Dieter ; Hund-Rinke, Kerstin ; Lahr, Joost ; Deneer, John - \ 2019
    Environmental Sciences Europe 31 (2019)1. - ISSN 2190-4707
    Bioavailability - Detoxification - NER - Risk assessment

    Background: Discussion concerning the bioavailability and ecotoxicological relevance of non-extractable residues (NER) in soil is still ongoing. Is NER formation a detoxification process or a hidden hazard? The use of radiolabelled chemicals enables detection of NER, but the identity of NER is usually unknown. Regulations require clear measurable parameters and the approach of Ortega-Calvo et al. (Environ Sci Technol 49:10255–10264, 2015) defines these. Results: Following that approach, we studied the fate of three ecotoxic, NER-forming chemicals over a period of 6 months after application to three different soils. Initial 14C experiments showed formation of NER for all chemicals. For the chemical 2,4,6-trinitrotoluene (TNT), NER-formation was reproducible in all soils. We applied a recently standardized method using Tenax® to remove the bioavailable fraction of the chemical at test start and test end. Removing the bioavailable fractions also removed toxicity. Further experiments without radiolabelled TNT clearly showed that the toxicity measured in applied soils was caused by the bioavailable chemical and not by NER. Conclusions: The tool developed can be used if the fate of the chemical including NER formation is well known and reproducible. The other selected chemicals, cypermethrin and carbendazim, showed unexpected behaviour in 14C-fate experiments. The degree of biodegradation was not reproducible for cypermethrin and unexpected losses occurred with carbendazim. This indicated a very large uncertainty when using non-radiolabelled compounds in NER experiments and thus the tool is not suitable in non-radiolabelled experiments.

    Integrated scenarios to support analysis of the food–energy–water nexus
    Vuuren, Detlef P. Van; Bijl, David L. ; Bogaart, Patrick ; Stehfest, Elke ; Biemans, Hester ; Dekker, Stefan C. ; Doelman, Jonathan C. ; Gernaat, David E.H.J. ; Harmsen, Mathijs - \ 2019
    Nature Sustainability 2 (2019)12. - ISSN 2398-9629 - p. 1132 - 1141.

    The literature emphasizes the important relationships between the consumption and production of food, energy and water, and environmental challenges such as climate change and loss of biodiversity. New tools are needed to analyse the future dynamics of this nexus. Here, we introduce a set of model-based scenarios and associated Sankey diagrams that enable analysis of the relevant relationships and dynamics, as well as the options to formulate response strategies. The scenarios show that if no new policies are adopted, food production and energy generation could further increase by around 60%, and water consumption by around 20% over the period 2015–2050, leading to further degradation of resources and increasing environmental pressure. Response strategies in terms of climate policies, higher agricultural yields, dietary change and reduction of food waste are analysed to reveal how they may contribute to reversing these trends, and possibly even lead to a reduction of land use in the future.

    Quantification of proteins in seaweeds
    Safi, Carl ; Leeuwen, J.J.A. van; Telleman, Yvette ; Engelen-Smit, N.P.E. ; Broek, L.A.M. van den; Harmsen, P.F.H. - \ 2018
    In: Protocols for Macroalgae Research / Charrier, B., Wichard, T., Reddy, C.R.K., Boca Raton : CRC Press, Taylor & Francis - ISBN 9781498796422 - p. 211 - 224.
    The protein quality and the amino acid composition are key elements for the valorization of seaweeds. Proteins represent a significant part of the primary composition of seaweeds. In this chapter, we describe several protocols for the characterization and quantification of proteins in seaweeds and in the crude extracts. The protocols described are hydrolysis methods, colorimetric methods, amino acid determination, and the determination of the nitrogen to protein conversion factor.
    Afbraak paks vergt heel veel geduld
    Harmsen, J. ; Rietra, R.P.J.J. - \ 2018
    biobased economy - sludges - biomass - water treatment
    Wat moeten we doen met zeewier?
    Groenestijn, J.W. van; Leeuwen, J.J.A. van; Harmsen, P.F.H. - \ 2018
    Validation of ISO 16751 Soil Quality - Environmental availability of non-polar organic compounds : Determination of the potentially bioavailable fraction and the non-bioavailable fraction using a strong adsorbent or complexing agent
    Vark, Winnie van; Klopstra, Ewoud ; Harmsen, Joop - \ 2018
    Wageningen : Wageningen Environmental Research (Wageningen Environmental Research report 2919) - 39
    ISO/TC190/Soil Quality has developed a standard to enable measurement of the bioavailability of organic contaminants in soil and soil like materials (ISO/TS16751), To become a full standard a validation is necessary. The validation is based on an intra laboratory validation carried out by the laboratory of Rijkswaterstaat in Lelystad (The Netherlands), and on an international interlaboratory validation study organized by WEPAL, Wageningen. Results are evaluated according ISO 5725. As decided by the responsible ISO-working group, the results support the transfer of ISO/TS 16751 into a full ISO-standard.
    Validation of ISO/DIS 20244 Soil quality - screening method for water content - determination by refractometry
    Vark, Winnie van; Pellen, Peter ; Crum, Steven ; Harmsen, Joop - \ 2018
    Wageningen : Wageningen Environmental Research (Wageningen Environmental Research report 2911) - 25
    ISO/TC190/Soil Quality has developed a standard to enable measurement of water content in soil and soil-like materials using a screening method ISO/DIS 20244. To become a full standard, the screening method required validation to show the applicability and comparability of the method in different laboratories (repeatability and reproducibility). This validation was organised by WEPAL, (Wageningen Evaluating Programs for Analytical Laboratories), which is part of Wageningen University in the Netherlands. 11 laboratories participated in the validation. Samples with comparable and known water content were distributed. Repeatability and reproducibility were calculated according ISO 5725. The measured water contents were lower than measured with ISO 11465. Probably the sucrose solution is not able to extract all water. Correction of the result using clay content and or organic matter content may be possible, but needs further investigation. The responsible ISO Working Group has to decide if and how the results can be added to ISO/DIS 20244 to become a full standard.
    Advances in the Development of Procedures to Establish the Toxicity of Non-Extractable Residues (NER) in Soil. LRI-ECO25
    Harmsen, Joop ; Hennecke, Dieter ; Hund-Rinke, Kerstin ; Lahr, Joost ; Deneer, John - \ 2018
    Wageningen : Wageningen Environmental Research (Wageningen Environmental Research report 2909) - 109
    There is already a long discussion around the bioavailability and ecotoxicological relevance of Non Extractable Residues (NER) in soil. Is NER formation a detoxification process or should it be considered a hidden hazard? NER can only be established using labelled chemicals (e.g. 14C) and cannot be measured with conventional chemical analytics. Regulations ask for understandable and measurable parameters. Considered in the developed tool are three measurable parameters: 1) Chemical present in the water phase, 2) A potentially available fraction in equilibrium with the water phase. 3) The total extractable amount. NER is considered, but mentioned as non-measurable and non-bioavailable. The fates of three NER-forming chemicals were followed in a period of 6 months after addition also using 14C chemicals. For the chemical Tri-NitroToluene (TNT), NER-formation was reproducible and NER formation during aging removed toxicity. By removing the bioavailable fractions directly after spiking and after aging it was also possible to remove toxicity. The experiments showed that toxicity was caused by the bioavailable chemical and not by NER. With Cypermethrin and Carbendazim, results were less clear, because there was a large uncertainty in NER-formation. The degree of biodegradation was not reproducible for Cypermethrin and unexpected losses occurred with Carbendazim and it is not possible to draw conclusions from only a non-labelled experiments.
    Bioeconomy mapping report, D 1.1 : An overview of the bioeconomy
    Bos, H.L. ; Kranendonk, R.P. ; Harmsen, P.F.H. ; Schrijver, R.A.M. ; Leeuwen, J.J.A. van - \ 2018
    EU (Bloom ) - 45 p.
    biobased economy - biomass - biobased materials - biobased chemistry
    Guide to evaluation of quality of surface water in coffee river basins of Colombia
    Rodríguez Valencia, Nelson ; Quintero Yepes, Laura Vanessa ; Gómez Zuluaga, Gustavo Adolfo ; Bohórquez Zapata, Viviana Lorena ; González Durán, Cristy Mayerly ; Osorio Ocampo, Andrés Felipe ; Miguel García, Ángel de; Harmsen, Joop ; Wolters, W. ; Miguel Ayala, L. - \ 2018
    Bogota : APC Columbia - 206
    Apppropriate technologies for water treatment on coffee farms
    Rodríguez Valencia, Nelson ; Quintero Yepes, Laura Vanessa ; Osorio Ocampo, Andrés Felipe ; Castañeda, Samuel Antonio ; Miguel García, Ángel de; Harmsen, Joop ; Bisschops, Iemke ; Wolters, W. ; Miguel Ayala, L. - \ 2018
    Bogota : APC Columbia - 130
    Check title to add to marked list
    << previous | next >>

    Show 20 50 100 records per page

     
    Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.