Different transcriptional response between susceptible and resistant common carp (Cyprinus carpio) fish hints on the mechanism of CyHV-3 disease resistance
Tadmor-Levi, Roni ; Doron-faigenboim, Adi ; Marcos-hadad, Evgeniya ; Petit, Jules ; Hulata, Gideon ; Forlenza, Maria ; Wiegertjes, Geert F. ; David, Lior - \ 2019
BMC Genomics 20 (2019)1. - ISSN 1471-2164
Infectious disease outbreaks form major setbacks to aquaculture production and to further development of this important sector. Cyprinid herpes virus-3 (CyHV-3) is a dsDNA virus widely hampering production of common carp (Cyprinus carpio), one of the most farmed fish species worldwide. Genetically disease resistant strains are highly sought after as a sustainable solution to this problem. To study the genetic basis and cellular pathways underlying disease resistance, RNA-Seq was used to characterize transcriptional responses of susceptible and resistant fish at day 4 after CyHV-3 infection.