Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Postprandial amino acid, glucose and insulin responses among healthy adults after a single intake of Lemna minor in comparison with green peas: A randomised trial
    Zeinstra, Gertrude G. ; Somhorst, Dianne ; Oosterink, Els ; Fick, Henriette ; Klopping-Ketelaars, Ineke ; Meer, Ingrid M. Van Der; Mes, Jurriaan J. - \ 2019
    Journal of Nutritional Science 8 (2019). - ISSN 2048-6790
    Duckweed - Glucose - Human trials - Insulin - Lemna minor - Plant-based protein - Safety

    A high protein content combined with its enormous growth capacity make duckweed an interesting alternative protein source, but information about postprandial responses in humans is lacking. The present study aimed to assess the postprandial serum amino acid profile of Lemna minor in healthy adults in comparison with green peas. A secondary objective was to obtain insights regarding human safety. A total of twelve healthy volunteers participated in a randomised, cross-over trial. Subjects received two protein sources in randomised order with a 1-week washout period. After an overnight fast, subjects consumed L. minor or peas (equivalent to 20 g of protein). After a baseline sample, blood samples were taken 15, 30, 45, 60, 75, 90, 120, 150 and 180 min after consumption to assess amino acid, glucose and insulin levels. Heart rate, blood pressure and aural temperature were measured before and after consumption, and subjects reported on gastrointestinal discomfort for four subsequent days. Compared with green peas, significantly lower blood concentrations of amino acids from L. minor were observed, indicating lower digestibility. L. minor consumption resulted in lower plasma glucose and insulin levels compared with peas, probably due to different glucose content. There were no significant differences concerning the assessed health parameters or the number of gastrointestinal complaints, indicating that a single bolus of L. minor-grown under controlled conditions-did not induce acute adverse effects in humans. Further studies need to investigate effects of repeated L. minor intake and whether proteins purified from L. minor can be digested more easily.

    Slowly biodegradable organic compounds impact the biostability of non-chlorinated drinking water produced from surface water
    Hijnen, W.A.M. ; Schurer, R. ; Bahlman, J.A. ; Ketelaars, H.A.M. ; Italiaander, R. ; Wal, A. van der; Wielen, P.W.J.J. van der - \ 2018
    Water Research 129 (2018). - ISSN 0043-1354 - p. 240 - 251.
    AOC-A3 - AOC-P17/Nox - Biopolymers - Biostability of drinking water - Regrowth - Slowly biodegradable compounds
    It is possible to distribute drinking water without a disinfectant residual when the treated water is biologically stable. The objective of this study was to determine the impact of easily and slowly biodegradable compounds on the biostability of the drinking water at three full-scale production plants which use the same surface water, and on the regrowth conditions in the related distribution systems. Easily biodegradable compounds in the drinking water were determined with AOC-P17/Nox during 2012–2015. Slowly biodegradable organic compounds measured as particulate and/or high-molecular organic carbon (PHMOC), were monitored at the inlet and after the different treatment stages of the three treatments during the same period. The results show that PHMOC (300–470 μg C L−1) was approximately 10% of the TOC in the surface water and was removed to 50–100 μg C L−1. The PHMOC in the water consisted of 40–60% of carbohydrates and 10% of proteins. A significant and strong positive correlation was observed for PHMOC concentrations and two recently introduced bioassay methods for slowly biodegradable compounds (AOC-A3 and biomass production potential, BPC14). Moreover, these three parameters in the biological active carbon effluent (BACF) of the three plants showed a positive correlation with regrowth in the drinking water distribution system, which was assessed with Aeromonas, heterotrophic plate counts, coliforms and large invertebrates. In contrast, the AOC-P17/Nox concentrations did not correlate with these regrowth parameters. We therefore conclude that slowly biodegradable compounds in the treated water from these treatment plants seem to have a greater impact on regrowth in the distribution system than easily biodegradable compounds.
    Moderate alcohol consumption after a mental stressor attenuates the endocrine stress response
    Schrieks, I.C. ; Joosten, M.M. ; Klöpping-Ketelaars, W.A.A. ; Witkamp, R.F. ; Hendriks, H.F.J. - \ 2016
    Alcohol 57 (2016). - ISSN 0741-8329 - p. 29 - 34.
    Alcohol - Cortisol - Immune system - Psychological stress - Trier Social Stress Test

    Alcohol is often consumed to reduce tension and improve mood when exposed to stressful situations. Previous studies showed that moderate alcohol consumption may reduce stress when alcohol is consumed prior to a stressor, but data on the effect of alcohol consumption after a mental stressor is limited. Therefore, our objective was to study whether moderate alcohol consumption immediately after a mental stressor attenuates the stress response. Twenty-four healthy men (age 21–40 y, BMI 18–27 kg/m2) participated in a placebo-controlled trial. They randomly consumed 2 cans (660 mL, ∼26 g alcohol) of beer or alcohol-free beer immediately after a mental stressor (Stroop task and Trier Social Stress Test). Physiological and immunological stress response was measured by monitoring heart rate and repeated measures of the hypothalamic-pituitary-adrenal axis (HPA-axis), white blood cells and a set of cytokines. After a mental stressor, cortisol and adrenocorticotropic hormone (ACTH) concentrations were 100% and 176% more reduced at 60 min (P = 0.012 and P = 0.001, respectively) and 92% and 60% more reduced at 90 min (P

    New growing media and value added organic waste processing
    Blok, C. ; Rijpsma, E. ; Ketelaars, J.J.M.H. - \ 2016
    Acta Horticulturae 1112 (2016). - ISSN 0567-7572 - p. 269 - 280.
    Biochar - Charification - Compost - Container plants - Peat alternatives - Torrefaction

    Public pressure to use peat alternatives in horticultural rooting media offers room for the re-use of local organic waste materials. The re-use of organic wastes requires value added processing such as composting, co-composting, digestion, fractioning/sieving, pressing, binding, stabilising by torrefaction and charification, washing and nutrient exchange. Three cases are presented. In case 1, the new growing media project showed a successful reduction of peat in potting soil mixes at nurseries of 15 plant species. Peat use decreased from 78 to 27%-v/v. The 51%-v/v extra peat alternatives used were, averaged over all mixes used, 24%-v/v coir products, 13%-v/v wood fibre, 6%-v/v bark products and 2%-v/v for each of compost, rice husks, perlite or rockwool granulate. When compared to the standard control mixes yield decreased for two species, increased for two species and was equal for the remaining species. Important, sometimes limiting, properties were stability, nitrogen fixation, EC level, sodium level, rewetting rate and water holding capacity. In case 2 torrefaction at 250°C was used to turn a fast degrading nitrate fixing reed (Phragmites australis) into a non-toxic potting soil constituent which could be added to potting soil mixes up to 80%-v/v. In case 3 the cation exchange complex of coir was measured and saturated with calcium ions. The amount and concentration of a solution necessary to exchange sodium and potassium was 600 meq kg-1 and was dosed as 10 L of 30 mmol L-1 calcium nitrate. In all 3 cases product quality measurements and adapted processing or cultivation practises were discussed. A set of the most important measurements is presented, including: pH, EC, EC level, sodium level, potassium level, stability, nitrogen fixation, easily available water and rewetting rate. In conclusion additional or adapted processing of organic waste guided by proper measurements can increase the value of such organic waste for use in horticulture.

    Smart Seafood
    Ketelaars, J.J.M.H. ; Tacken, W. - \ 2014
    zout water - voedselproductie - nieuwe producten - zoutwaterlandbouw - landbouw - nieuwe voedingsmiddelen - alternatieve landbouw - teelt - saline water - food production - new products - saline agriculture - agriculture - novel foods - alternative farming - cultivation
    Met de slogan ‘Land in Zee’ profileert de provincie Zeeland zich als de plek waar de zee altijd en overal dichtbij is. Die nabijheid nodigt uit om te profiteren van de unieke mogelijkheden van zoutwater voor recreatie en natuur, maar ook voor de productie van voedsel. Met het programma Smart Seafood wil de provincie slim gebruik van zoutwater en zilte omstandigheden binnendijks bevorderen. Dat kan door kennis en kennisontwikkeling te verbinden met ondernemerschap. Waar liggen de kansen voor nieuwe producten uit een zout of zilt milieu?
    Toekomstperspectief voor het gemengd zilt bedrijf
    Ketelaars, J.J.M.H. ; Ruizeveld de Winter, A.C. - \ 2014
    Wageningen : Plant Research International, Business Unit Agrosyteemkunde (Rapport / Plant Research International 545) - 66
    zoutwaterlandbouw - landbouw - toekomst - visteelt - aquacultuur - agrarische economie - zeeland - haalbaarheidsstudies - economische haalbaarheid - saline agriculture - agriculture - future - fish culture - aquaculture - agricultural economics - zeeland - feasibility studies - economic viability
    Op het Proefbedrijf Zeeuwse Tong in Colijnsplaat is gedurende vier jaren (2010-2013) ervaring opgedaan met de kweek van zagers, tong, algen, en schelpdieren, waaronder tapijtschelpen, Japanse oesters en platte oesters. In onderstaande worden de belangrijkste ervaring en met de verschillende teelten afzonderlijk en in combinatie samengevat. Vervolgens komen aan bod: de technische en economische haalbaarheid, en de risico’s en onzekerheden.
    Perspectief voor binnendijkse kweek
    Ketelaars, J.J.M.H. - \ 2013
    Goes : Stichting Zeeuwse Tong - 65
    aquacultuur - zoutwaterlandbouw - visteelt - agropisciculture - zeeland - zout water - tong (vis) - algen - schaaldieren - oesters - mossels - haalbaarheidsstudies - aquacultuursystemen - aquaculture - saline agriculture - fish culture - agropisciculture - zeeland - saline water - dover soles - algae - shellfish - oysters - mussels - feasibility studies - aquaculture systems
    In 2009 startte Stichting Zeeuwse Tong een vijfjarig proefproject met als doel: 1. op praktijkschaal technische en economische kennis te verzamelen van binnendijkse zoutwateraquacultuur, in het bijzonder van de productie van tong, zagers, algen, schelpdieren en zilte gewassen, en 2. om deze kennis beschikbaar te maken voor geïnteresseerde ondernemers. De motivatie voor het Proefproject is tweeledig: 1. kansen benutten voor zoutwateraquacultuur gezien de toenemende vraag naar en interesse in zeevoedsel, 2. alternatieven ontwikkelen voor het gebruik van landbouwgrond die toenemende hinder ondervindt van verzilting. Deze rapportage geeft een samenvatting van de belangrijkste R&D-resultaten. Tegen deze achtergrond worden vervolgens de technische en economische haalbaarheid, de risico’s en onzekerheden besproken van de verschillende teelten of bedrijfsvormen.
    Zeeuwse tong steeds dichter bij het bord
    Ketelaars, J.J.M.H. - \ 2011
    Kennis Online 2011 (2011)14 juni. - p. 14 - 14.
    visteelt - aquacultuur - schaal- en schelpdierenteelt - solea - tong (vis) - proefbedrijven - zeeland - fish culture - aquaculture - shellfish culture - solea - dover soles - pilot farms - zeeland
    De Nederlandse overheid heeft samen met het bedrijfsleven vijftien miljoen euro geïnvesteerd in het project Zeeuwse tong. De proefboerderij die dit jaar zijn eerste tong moet gaan afleveren, moet de start zijn van een hele nieuwe bedrijfstak: zilte gemengde teelt van vis en groenten.
    Zitle Teelt: Eerste zagers gaan begin mei in de kweekbassins - Proefbedrijf Zeeuwse Tong bijna klaar voor productie ( interview met W. Brandenburg en J. Ketelaars)
    Jansen, B. ; Brandenburg, W.A. ; Ketelaars, J.J.M.H. - \ 2010
    Provinciale Zeeuwse Courant (2010).
    Colonization of torrefied grass fibers by plant beneficial microorganisms
    Trifonova, R.D. ; Babini, V. ; Postma, J. ; Ketelaars, J.J.M.H. ; Elsas, J.D. van - \ 2009
    Applied Soil Ecology 41 (2009)1. - ISSN 0929-1393 - p. 98 - 106.
    pythium damping-off - serratia-plymuthica - pseudomonas-corrugata - rhizoctonia-solani - biological-control - biocontrol strain - soil - suppression - bacterial - rot
    This study aimed to assess the colonization of thermally treated (i.e. torrefied) grass fibers (TGFs), a new prospective ingredient of potting soil. Eleven bacterial strains and one fungus, Coniochaeta ligniaria F/TGF15, all isolated from TGF or its extract after inoculation with a soil microbial community, were tested for their ability to colonize TGF. Surprisingly, none of these bacteria were able to directly colonize TGF either as single inoculants or as a consortium. Furthermore, bacterial persistence or growth in TGF was not improved by the addition of nutrients or a surfactant. Only extensive washing of the substrate, presumably removing bacteriostatic or bactericidal compounds, allowed bacterial growth on the fibers. Strikingly, the fungal strain consistently colonized TGF up to high densities (up to 1010 CFU per g dry TGF). Given the unique capacity of this fungus to degrade toxic compounds including phenols, TGF was colonized with it for different periods of time, after which a consortium of seven selected bacterial isolates was added. Co-presence of the fungus, or 3 and 24 h pre-colonization with it, was insufficient to create a habitable environment for the bacterial consortium. However, fungal pre-colonization of minimally 3 days allowed the bacterial consortium to colonize the TGF at numbers up to 109 to 1010 CFU per g dry substrate. The resultant bacterial community consisted of at least four strains, i.e. Pseudomonas putida 15/TGE5, Serratia plymuthica 23/TGE5, Pseudomonas corrugata 31/TGE5, and Methylobacterium radiotolerans 56/TGF10, as shown by PCR of colonies on plates and PCR–DGGE profiling. Two persisters, S. plymuthica 23/TGE5 and P. corrugata 31/TGE5, were highly antagonistic towards several phytopathogenic fungi. Thus, a microbial community with plant-beneficial potential was established on TGF, provided that the fungus C. ligniaria F/TGF15 first creates habitable space in the matrix
    Removal of phytotoxic compounds from torrefied grass fibres by plant-beneficial microorganisms
    Trifonova, R.D. ; Postma, J. ; Verstappen, F.W.A. ; Bouwmeester, H.J. ; Ketelaars, J.J.M.H. ; Elsas, J.D. van - \ 2008
    FEMS microbiology ecology 66 (2008)1. - ISSN 0168-6496 - p. 158 - 166.
    mill waste-water - escherichia-coli - phenolic removal - laccase activity - growth - strain - peat - detoxification - fermentation - enzyme
    We aimed to select microorganisms colonizing torrefied grass fibres (TGF) and simultaneously reducing the phytotoxicity which appeared after heat treatment of the fibres. Eighty-eight bacterial strains and one fungus, previously isolated from a sequential enrichment experiment on torrefied fibres and extracts, were tested separately for their capacity to decrease phytotoxicity. Eleven of the bacterial strains and the fungus significantly reduced phytotoxicity. These organisms were checked for their ability to grow on agar containing phenol, 2-methoxyphenol, 2,6-dimethoxyphenol, 2-furalaldehyde, pyrrole-2-carboxaldehyde and furan-2-methanol as sole carbon sources. The fungus F/TGF15 and the bacterial strain 66/TGF15 were able to grow on all six compounds. Strains 15/TGE5, 23/TGE5, 43/TGE20, 56/TGF10 and 95/TGF15 grew on two to four compounds, and strain 72/TGF15 only on one compound. Strains 31/TGE5, 34/TGE5, 48/TGE20 and 70/TGF15 did not grow on any of the single toxic compounds. GC analyses of torrefied grass extracts (TGE) determined which compounds were removed by the microorganisms. F/TGF15 was the only isolate depleting phenol, 2-methoxyphenol, 2-dihydrofuranone and pyrrole-2,5-dione-3-ethyl-4-methyl. Strains 15/TGE5, 23/TGE5, 31/TGE5 and 56/TGF10, and the fungus depleted 2-furalaldehyde, 2-furan-carboxaldehyde-5-methyl, pyrrole-2-carboxaldehyde, 5-acetoxymethyl-2-furaldehyde and benzaldehyde-3-hydroxy-4-methoxy. These promising candidates for colonizing and simultaneously reducing the phytotoxicity of TGF were affiliated with Pseudomonas putida, Serratia plymuthica, Pseudomonas corrugata, Methylobacterium radiotolerans and Coniochaeta ligniaria.
    Thermally treated grass fibers as colonizable substrate for beneficial bacterial inoculum
    Trifonova, R.D. ; Postma, J. ; Ketelaars, J.J.M.H. ; Elsas, J.D. van - \ 2008
    Microbial Ecology 56 (2008)3. - ISSN 0095-3628 - p. 561 - 571.
    coconut coir dusts - sp-nov. - soil - methylobacterium - 4-chlorophenol - microorganisms - phytotoxicity - populations - sequence - removal
    This study investigates how thermally treated (i.e., torrefied) grass, a new prospective ingredient of potting soils, is colonized by microorganisms. Torrefied grass fibers (TGF) represent a specific colonizable niche, which is potentially useful to establish a beneficial microbial community that improves plant growth. TGF and torrefied grass extracts (TGE) were inoculated with a suspension of microorganisms obtained from soil. Sequential microbial enrichment steps were then performed in both substrates. The microbial communities developing in the substrates were assessed using cultivation-based and cultivation-independent approaches. Thus, bacterial isolates were obtained, and polymerase chain reaction¿denaturing gradient gel electrophoresis (DGGE) analyses for bacterial communities were performed. Partial sequencing of the 16S ribosomal RNA gene from isolates and bands from DGGE gels showed diverse communities after enrichment in TGE and TGF. Bacterial isolates affiliated with representatives of the ¿-proteobacteria (Methylobacterium radiotolerans, Rhizobium radiobacter), ¿-proteobacteria (Serratia plymuthica, Pseudomonas putida), Cytophaga¿Flavobacterium¿Bacteroides (CFB) group (Flavobacterium denitrificans), ß-proteobacteria (Ralstonia campinensis), actinobacteria (Cellulomonas parahominis, Leifsonia poae, L. xyli subsp. xyli, and Mycobacterium anthracenicum), and the firmicutes (Bacillus megaterium) were found. In TGE, ¿-proteobacteria were dominant (61.5% of the culturable community), and 20% belonged to the CFB group, whereas actinobacteria (67.4%) and ¿-proteobacteria (21.7%) were prevalent in TGF. A germination assay with lettuce seeds showed that the phytotoxicity of TGF and TGE decreased due to the microbial enrichment
    Prediction of fecal and urinary N excretion in dairy cattle
    Evert, F.K. van; Meer, H.G. van der; Ketelaars, J.J.M.H. - \ 2007
    In: Ammonia emissions in agriculture / Monteny, G.J., Hartung, E., Wageningen : Wageningen Academic Publishers - ISBN 9789086860296 - p. 91 - 93.
    Towards a dairy farm that produces more than milk
    Ketelaars, J.J.M.H. ; Evert, F.K. van; Rutgers, B. - \ 2006
    In: Changing European farming systems for a better future. New visions for rural areas,. - Wageningen : Wageningen Academic Publishers - ISBN 9789086860029 - p. 183 - 183.
    Fytotoxiciteit, nematotoxiciteit, en microbiele stabiliteit van getorreficeerd gras
    Zoon, F.C. ; Kok, C.J. ; Ketelaars, J.J.M.H. - \ 2006
    Wageningen : Plant Research International (Nota / Plant Research International 380) - 30
    groeimedia - plantenresten - grassen - phragmites - vezelgewassen - fytotoxiciteit - torrefactie - growing media - plant residues - grasses - phragmites - fibre plants - phytotoxicity - torrefaction
    Scheppen van ruimte : systeeminnovaties voor duurzame voedselproductie, werkplannen 2005
    Neeteson, J.J. ; Koops, A.J. ; Ketelaars, J.J.M.H. ; Vosman, B. ; Sijtsma, L. ; Wolfert, J. ; Kampers, F.W.H. - \ 2005
    Wageningen : Plant Research International (Nota Plant Research International 344) - 44 p.
    Scheppen van ruimte : systeeminnovaties voor duurzame voedselproductie, jaarverslag 2004
    Neeteson, J.J. ; Koops, A.J. ; Ketelaars, J.J.M.H. ; Vosman, B. ; Sijtsma, L. ; Wolfert, J. ; Kampers, F.W.H. - \ 2005
    Wageningen : Plant Research International (Nota / Plant Research International 343) - 44
    voedselproductie - systeemanalyse - innovaties - duurzaamheid (sustainability) - marketing van voedingsmiddelen - voedselvoorziening - microbiële eiwitten - landbouwontwikkeling - nederland - food production - systems analysis - innovations - sustainability - food marketing - food supply - microbial proteins - agricultural development - netherlands
    Ruimte wordt in toenemende mate een schaars goed. Zowel nationaal als mondiaal is er sprake van een gevecht om deze schaarse ruimte. Er zijn claims vanuit diverse hoeken waaronder landbouw, natuur en recreatie, energieproductie, stedelijke ontwikkeling en waterberging. Duurzame voedselproductie kan niet los gezien worden van duurzaam ruimtegebruik. Het programma Scheppen van Ruimte wil aan dit proces een bijdrage leveren. Het bestrijkt bewust een breed terrein van onderzoek vanuit de gedachte dat er geen unieke oplossing bestaat, maar dat de toekomst veelvormig zal zijn. Systeeminnovaties zijn daarom nodig om het ruimteconflict tussen de verschillende functies te verzachten. De voedselproductie-functie moet ruimte scheppen voor andere functies
    Nieuwe landbouw: inventarisatie van kansen
    Langeveld, J.W.A. ; Koops, A.J. ; Ketelaars, J.J.M.H. ; Marcelis, L.F.M. ; Hassink, J. ; Blom, M. ; Sanden, P.A.C.M. van de - \ 2005
    onbekend : PRI Agrosysteemkunde (Nota / Plant Research International 330) - 84
    landbouw - tuinbouw - teelt onder bescherming - biologische landbouw - natuurbescherming - bio-energie - non-food producten - landbouwproducten - zorgboerderijen - multifunctionele landbouw - biobased economy - biomassa productie - agriculture - horticulture - protected cultivation - organic farming - nature conservation - bioenergy - non-food products - agricultural products - social care farms - multifunctional agriculture - biobased economy - biomass production
    In opdracht van het Ministerie van LNV inventariseerde en evalueerde PRI de nieuwe productiekansen voor de Nederlandse plantaardige sectoren.Tevens doet PRI aanbevelingen voor beleid en onderzoek. Nieuwe landbouw is één van de projecten van het Transitieteam van het Ministerie. Behandelde thema's in dit rapport: landbouwgrondstoffen, zoutwater landbouw, kasteelt, sociale dienstverlening, ecologische dienstverlening, het nieuwe consumeren en Nederland regieland
    Serum carotenoids and vitamins in relation to markers of endothelial function and inflammation
    Broekmans, W. ; Klopping-Ketelaars, I.A.A. ; Bots, M.L. ; Kluft, C. ; Princen, H. ; Hendriks, H.F.J. ; Tijburg, L.B.M. ; Poppel, G. van; Kardinaal, A.F.M. - \ 2004
    European Journal of Epidemiology 19 (2004)10. - ISSN 0393-2990 - p. 915 - 921.
    coronary-heart-disease - low-density-lipoprotein - c-reactive protein - cardiovascular-disease - myocardial-infarction - beta-carotene - adhesion molecules - risk-factors - healthy-men - lycopene concentration
    Background: Endothelial cell dysfunction may be related to an increase in cellular oxidative stress. Carotenoids and vitamins could have an antioxidant-mediated tempering influence on endothelial function and inflammation, thereby reducing the risk of atherosclerosis. Methods: We measured serum carotenoids, alpha-tocopherol and Vitamin C concentrations in 379 subjects sampled from the general population. High-sensitive C-reactive protein (CRP), fibrinogen (Fbg) and leukocytes were measured as markers of inflammation. Furthermore, soluble intercellular adhesion molecule-1 (sICAM- 1) and flow-mediated vasodilation (FMD; n = 165) were measured as markers of endothelial function. Relationships between serum carotenoids and vitamins and markers of endothelial function and inflammation were analysed after adjustment for confounding. Results: In the total study group, lutein and lycopene were inversely related to sICAM- 1 with regression-coefficients of -0.38 +/- 0.19 (p = 0.04) and) 0.16 +/- 0.08 (p = 0.04) per 1 mumol/l, respectively. beta-Carotene was inverse related to leukocytes (-0.23 +/- 0.07; p = 0.007) and CRP (-1.09 +/- 0.30; p = 0.0003) per 1 mumol/l. Vitamin C was inverse related to CRP (-0.01 +/- 0.005; p = 0.04) per 1 mumol/l, whereas alpha-tocopherol was positively related to CRP (0.03 +/- 0.01; p = 0.02) per 1 mu/l. Zeaxanthin was inversely related to FMD (31.2 +/- 15.3; p = 0.04) per 1 mumol/l. Conclusion: The inverse relations between carotenoids, Vitamin C and sICAM- 1, CRP and leukocytes may help to explain the possible protective effect of carotenoids and Vitamin C on atherosclerosis through an influence on inflammatory processes and endothelial function.
    Scheppen van Ruimte: systeeminnovaties voor duurzame voedselproductie, werkplannen 2004
    Neeteson, J.J. ; Koops, A.J. ; Ketelaars, J.J.M.H. ; Loo, E.N. van; Vosman, B. ; Sijtsma, L. ; Wolfert, J. ; Kampers, F.W.H. - \ 2004
    Wageningen : Plant Research International (Nota / Plant Research International 289) - 28 p.
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