Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Antenatal multiple micronutrient supplementation: call to action for change in recommendation
    Bourassa, Megan W. ; Osendarp, Saskia J.M. ; Adu‐Afarwuah, Seth ; Ahmed, Saima ; Ajello, Clayton ; Bergeron, Gilles ; Black, Robert ; Christian, Parul ; Cousens, Simon ; Pee, Saskia de; Dewey, Kathryn G. ; Arifeen, Shams El ; Engle‐Stone, Reina ; Fleet, Alison ; Gernand, Alison D. ; Hoddinott, John ; Klemm, Rolf ; Kraemer, Klaus ; Kupka, Roland ; McLean, Erin ; Moore, Sophie E. ; Neufeld, Lynnette M. ; Persson, L. ; Rasmussen, Kathleen M. ; Shankar, Anuraj H. ; Smith, Emily ; Sudfeld, Christopher R. ; Udomkesmalee, Emorn ; Vosti, Stephen A. - \ 2020
    Annals of the New York Academy Of Sciences 1465 (2020)1. - ISSN 0077-8923 - p. 5 - 7.
    Translational and Implementation Research to Bridge Evidence and Implementation
    Kraemer, Klaus ; Zutphen, Kesso Gabrielle Van - \ 2019
    Annals of Nutrition & Metabolism 75 (2019)2. - ISSN 0250-6807 - p. 144 - 148.
    Implementation - Malnutrition - Policy - Programs - Research - Science - Translational

    Background: The role of science in guiding interventions and programs and contributing to progress in achieving global targets is undeniable. In public health nutrition, biological research in the past century focused largely on single nutrients and provided the basis for addressing nutritional deficiencies. This focus has now expanded to consider evidence including, but not limited, to knowledge about food, diet, behavior, context, and culture. The complex double burden of malnutrition will need to be addressed through a wider lens that appreciates the multiple and interrelated facets that underpin it. Summary: Despite the acknowledged importance of translational research in improving nutritional outcomes, significant gaps remain in the process leading from science to practice. This article sheds light on 2 examples that demonstrate this, namely, anemia and stunting. Further, much work is still required to translate the current evidence base into effective actions that result in impact at scale, pointing toward the need for more implementation research in nutrition. Key Messages: While discoveries may take time to surface and implementers are impatient to address the challenge at hand, it is essential to identify and deploy the best available evidence while continuously advancing the evidence base, and to seek the right balance between action and inaction.

    Ein neuer Gesellschaftsvertrag für eine nachhaltige Landwirtschaft : Wege zu einer integrativen Politik für den Agrarsektor
    Feindt, P.H. ; Kraemer, Christine ; Früh-Müller, Andrea ; Heissenhuber, A. ; Pahl-Wostl, Claudia ; Purnhagen, K. ; Thomas, Fabian van; Bers, Caroline van; Wolters, Volkmar - \ 2019
    Springer - ISBN 9783662586556 - 295 p.
    Die Landwirtschaft in Deutschland, Europa und weltweit befindet sich in einem dramatischen Umbruchprozess. Einerseits bieten Liberalisierung und Marktöffnung, neue technologische Entwicklungen, die wachsende Weltbevölkerung und neue Kundenwünsche vielen landwirtschaftlichen Betrieben neue Möglichkeiten. Andererseits stehen viele Landwirtinnen und Landwirte in internationaler Konkurrenz, sind zum betrieblichen Wachstum mit hohem Investitionsrisiko gezwungen, sind Teil strikt regulierter Wertschöpfungsketten und müssen steigenden gesellschaftlichen Ansprüchen genügen. Zugleich machen sich viele Menschen Sorgen, dass die Prozesse der Rationalisierung und Modernisierung der landwirtschaftlichen Produktion auf Kosten von Natur-, Umwelt- und Tierschutz gehen. Auf vielen Ebenen wird daher bereits nach einer neuen Verständigung darüber gesucht, was die Gesellschaft von der Landwirtschaft erwartet, und welche Unterstützung die Landwirtinnen und Landwirte im Gegenzug dafür erwarten dürfen. Vor diesem Hintergrund entwickelt das vorliegende Open Access-Buch eine wissenschaftlich fundierte Kritik der Umweltauswirkungen der Landwirtschaft und der politischen Logik der Agrarpolitik. Es präsentiert ein neues Leitbild mit konkreten Indikatoren sowie alternative strategische Handlungsoptionen. Die umfassende Analyse wird zu einem Vorschlag für eine neue Architektur der europäischen Agrarpolitik gebündelt, die eine breite Diskussion um einen Neuen Gesellschaftsvertrag für die Landwirtschaft in Deutschland und Europa anstoßen soll.
    Review of the evidence regarding the use of antenatal multiple micronutrient supplementation in low- and middle-income countries
    Bourassa, Megan W. ; Osendarp, Saskia J.M. ; Adu-Afarwuah, Seth ; Ahmed, Saima ; Ajello, Clayton ; Bergeron, Gilles ; Black, Robert ; Christian, Parul ; Cousens, Simon ; Pee, Saskia de; Dewey, Kathryn G. ; Arifeen, Shams El ; Engle-Stone, Reina ; Fleet, Alison ; Gernand, Alison D. ; Hoddinott, John ; Klemm, Rolf ; Kraemer, Klaus ; Kupka, Roland ; McLean, Erin ; Moore, Sophie E. ; Neufeld, Lynnette M. ; Persson, Lars Åke ; Rasmussen, Kathleen M. ; Shankar, Anuraj H. ; Smith, Emily ; Sudfeld, Christopher R. ; Udomkesmalee, Emorn ; Vosti, Stephen A. - \ 2019
    Annals of the New York Academy Of Sciences 1444 (2019)1. - ISSN 0077-8923 - p. 6 - 21.
    LMICs - micronutrient - pregnancy - supplements

    Inadequate micronutrient intakes are relatively common in low- and middle-income countries (LMICs), especially among pregnant women, who have increased micronutrient requirements. This can lead to an increase in adverse pregnancy and birth outcomes. This review presents the conclusions of a task force that set out to assess the prevalence of inadequate micronutrient intakes and adverse birth outcomes in LMICs; the data from trials comparing multiple micronutrient supplements (MMS) that contain iron and folic acid (IFA) with IFA supplements alone; the risks of reaching the upper intake levels with MMS; and the cost-effectiveness of MMS compared with IFA. Recent meta-analyses demonstrate that MMS can reduce the risks of preterm birth, low birth weight, and small for gestational age in comparison with IFA alone. An individual-participant data meta-analysis also revealed even greater benefits for anemic and underweight women and female infants. Importantly, there was no increased risk of harm for the pregnant women or their infants with MMS. These data suggest that countries with inadequate micronutrient intakes should consider supplementing pregnant women with MMS as a cost-effective method to reduce the risk of adverse birth outcomes.

    Dietary Vitamin A intake recommendations revisited : Global confusion requires alignment of the units of conversion and expression
    Melse-Boonstra, Alida ; Vossenaar, Marieke ; Loo-Bouwman, Carolien A. Van; Kraemer, Klaus ; Pee, Saskia de; West, Keith P. ; Russell, Robert M. ; Solomons, Noel W. - \ 2017
    Public Health Nutrition 20 (2017)11. - ISSN 1368-9800 - p. 1903 - 1906.
    Educating and training a workforce for nutrition in a post-2015 world
    Fanzo, Jessica C. ; Graziose, Matthew M. ; Kraemer, Klaus ; Gillespie, Stuart ; Johnston, Jessica L. ; Pee, Saskia de; Monterrosa, Eva ; Badham, Jane ; Bloem, Martin W. ; Dangour, Alan D. ; Deckelbaum, Richard ; Dobermann, Achim ; Fracassi, Patrizia ; Hossain, S.M.M. ; Ingram, John ; Jerling, Johann C. ; Jones, C.J. ; Jap, Stefanus Indrayana ; Kiess, Lynnda ; Marshall, Quinn ; Martin, Keith ; Narayan, Anuradha ; Amuyunzu-Nayamongo, Mary ; Pepping, Fré ; West, Keith P. - \ 2015
    Advances in Nutrition 6 (2015). - ISSN 2161-8313 - p. 639 - 647.
    Capacity development - Malnutrition - Sustainable development goals - Training - Workforce

    Nearly all countries in the world today are burdened with malnutrition, manifesting as undernutrition, micronutrient deficiencies, and/or overweight and obesity. Despite some progress, efforts to alleviate malnutrition are hampered by a shortage in number, skills, and geographic coverage, of a workforce for nutrition. Here, we report the findings of the Castel Gandolfo workshop, a convening of experts from diverse fields in March 2014 to consider how to develop the capacity of a global cadre of nutrition professionals for the post-2015 development era. Workshop participants identified several requirements for developing a workforce for nutrition, including an ability to work as part of a multisectoral team; communication, advocacy, and leadership skills to engage decision makers; and a set of technical skills to address future challenges for nutrition. Other opportunities were highlighted that could immediately contribute to capacity development, including the creation of a consortium to link global North and South universities, online training modules for middle managers, and practical, hands-on experiences for frontline nutrition workers. Institutional and organizational support is needed to enable workshop recommendations on education and training to be effectively implemented and sustained. The findings from the Castel Gandolfo workshop can contribute to the delivery of successful nutrition-relevant actions in the face of mounting external pressures and informing and attaining the forthcoming Sustainable Development Goals.

    Addressing the risk of inadequate and excessive micronutrient intakes: traditional versus new approaches to setting adequate and safe micronutrient levels in foods
    Bruins, M.J. ; Mugambi, G.K. ; Verkaik-Kloosterman, J. ; Hoekstra, J. ; Kraemer, K. ; Osendarp, S.J.M. ; Melse, A. ; Gallagher, A.M. ; Verhagen, H. - \ 2015
    Food and Nutrition Research 59 (2015). - ISSN 1654-661X - 9 p.
    Fortification of foods consumed by the general population or specific food products or supplements designed to be consumed by vulnerable target groups is amongst the strategies in developing countries to address micronutrient deficiencies. Any strategy aimed at dietary change needs careful consideration, ensuring the needs of at-risk subgroups are met whilst ensuring safety within the general population. This paper reviews the key principles of two main assessment approaches that may assist developing countries in deciding on effective and safe micronutrient levels in foods or special products designed to address micronutrient deficiencies, that is, the cut-point method and the stepwise approach to risk–benefit assessment. In the first approach, the goal is to shift population intake distributions such that intake prevalences below the Estimated Average Requirement (EAR) and above the Tolerable Upper Intake Level (UL) are both minimized. However, for some micronutrients like vitamin A and zinc, a narrow margin between the EAR and UL exists. Increasing their intakes through mass fortification may pose a dilemma; not permitting the UL to be exceeded provides assurance about the safety within the population but can potentially leave a proportion of the target population with unmet needs, or vice versa. Risk–benefit approaches assist in decision making at different micronutrient intake scenarios by balancing the magnitude of potential health benefits of reducing inadequate intakes against health risks of excessive intakes. Risk–benefit approaches consider different aspects of health risk including severity and number of people affected. This approach reduces the uncertainty for policy makers as compared to classic cut-point methods.
    Effect of fish oil on ventricular tachyarrhythmia in three studies in patients with implantable cartioverter defibrillators
    Brouwer, I.A. ; Raitt, M.H. ; Dullemeijer, C. ; Kraemer, D.F. ; Zock, P.L. ; Morris, C. ; Katan, M.B. ; Connor, W.E. ; Camm, J.A. ; Schouten, E.G. ; McAnulty, J. - \ 2009
    European Heart Journal 30 (2009)7. - ISSN 0195-668X - p. 820 - 826.
    polyunsaturated fatty-acids - reinfarction trial dart - coronary-heart-disease - sudden-death - myocardial-infarction - risk - supplementation - metaanalysis - arrhythmias - prevention
    Aims: To determine the effects of omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish on the incidence of recurrent ventricular arrhythmia in implantable cardioverter defibrillator (ICD) patients by combining results from published trials. Methods and results: We searched in the Medline, EMBASE, and Cochrane databases and performed a meta-analysis on all three available trials on fish oil and ventricular arrhythmia. Furthermore, we pooled individual data of two of these randomized, double-blind, placebo-controlled trials (Raitt et al. Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial. JAMA 2005;293:2884¿2891 and Brouwer et al. Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial. JAMA 2006;295:2613¿2619). The main outcome was time to first confirmed ventricular fibrillation (VF) or ventricular tachycardia (VT) combined with death for the meta-analysis, and time to first spontaneous confirmed VF or VT for the pooled analysis. The meta-analysis (n = 1148) showed no convincing protective effect of fish oil (RR 0.90; 95% CI 0.67¿1.22). The hazard ratio for the subgroup of patients with coronary artery disease at baseline (0.79; 0.60¿1.06) tended towards a protective effect. The pooled analysis (n = 722) showed that time to appropriate ICD intervention was similar for fish oil and placebo treatment (log-rank P = 0.79). Conclusion: These findings do not support a protective effect of omega-3 PUFAs from fish oil on cardiac arrhythmia in all patients with an ICD. Current data neither prove nor disprove a beneficial or a detrimental effect for subgroups of patients with specific underlying pathologies
    Effect of fish oil on ventricular tachyarrhythmia in patients with implantable defibrillators: a pooled analysis
    Brouwer, I.A. ; Raitt, M.H. ; Dullemeijer, C. ; Kraemer, D.F. ; Zock, P.L. ; Morris, C. ; Katan, M.B. ; Connor, W.E. ; Schouten, E.G. ; McAnulty, J. - \ 2007
    Circulation 115 (2007)8. - ISSN 0009-7322 - p. E274 - E274.
    Temperatuuronderzoek bij Paprika seizoen 1990 - 1991
    Maaswinkel, R. ; Janse, J. ; Elzo Kraemer, C. - \ 1991
    Naaldwijk : Proefstation voor Tuinbouw onder Glas (Intern verslag / Proefstation voor Tuinbouw onder Glas 34) - 11
    Downstream processing in biotechnology.
    Howell, J. ; Kraemer, P. ; Nybergh, P. ; Riet, K. van 't; Schmidt-Kastner, G. ; Skogman, H. ; Sittig, W. ; Vosser, W. - \ 1986
    In: Dechema, Frankfurt a. M. (1986) 10-19 / Schmidt-Kastner, G., Kraemer, P., - p. 30 - 34.
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