Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

    Records 1 - 20 / 20

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    Novel tools for extraction and validation of disease-related mutations applied to fabry disease
    Kuipers, R.K.P. ; Bergh, T. ; Joosten, H.J. ; Lekanne dit Deprez, R.H. ; Mannens, M.M.A.M. ; Schaap, P.J. - \ 2010
    Human Mutation 31 (2010)9. - ISSN 1059-7794 - p. 1026 - 1032.
    ligand-binding domain - alpha-galactosidase-a - iarc tp53 database - protein - identification - polymorphisms - knowledgebase - residues
    Genetic disorders are often caused by nonsynonymous nucleotide changes in one or more genes associated with the disease. Specific amino acid changes, however, can lead to large variability of phenotypic expression. For many genetic disorders this results in an increasing amount of publications describing phenotype-associated mutations in disorder-related genes. Keeping up with this stream of publications is essential for molecular diagnostics and translational research purposes but often impossible due to time constraints: there are simply too many articles to read. To help solve this problem, we have created Mutator, an automated method to extract mutations from full-text articles. Extracted mutations are crossreferenced to sequence data and a scoring method is applied to distinguish false-positives. To analyze stored and new mutation data for their (potential) effect we have developed Validator, a Web-based tool specifically designed for DNA diagnostics. Fabry disease, a monogenetic gene disorder of the GLA gene, was used as a test case. A structure-based sequence alignment of the alpha-amylase superfamily was used to validate results. We have compared our data with existing Fabry mutation data sets obtained from the HGMD and Swiss-Prot databases. Compared to these data sets, Mutator extracted 30% additional mutations from the literature
    The forestry agent at the interface between local-level environment management and external policies: reflections on forestry interventions in the Sahel.
    Lekanne dit Deprez, B.E.J.C. ; Wiersum, K.F. - \ 1995
    In: Local resource management / van den Breemer, J.P.M., - p. 229 - 242.
    Evaluation as contested knowledge.
    Lekanne dit Deprez, B. - \ 1995
    In: In search of the middle ground: essays on the sociology of planned development: Liber amicorum Dirk van Dusseldorp / Frerks, G., den Ouden, J.H.B., Dept. Sociology, Section Sociology of Rural Development, Wageningen - p. 114 - 128.
    Boekbespreking: Landhervorming en landbouwontwikkeling; een politiek economische analyse van de landhervorming in de Dominikaanse Republiek, J.P. de Groot. Amsterdam 1991.
    Lekanne, B. - \ 1992
    Tijdschrift voor sociaalwetenschappelijk onderzoek van de landbouw 7 (1992). - ISSN 0921-481X - p. 279 - 282.
    Boekbespreking: Irrigatielandbouw in Afrika. La vallée du fleuve Sénégal; évaluations et perspectives d'une décennie d'aménagement, B. Crousse, P. Mathieu, S.M. Seck (red.). Paris 1991.
    Lekanne, B. - \ 1992
    Derde wereld 11 (1992)2. - ISSN 0167-4498 - p. 86 - 88.
    Boekbespreking: Traditionele landbouw als genenbank, W. van der Heide, B. Lekanne dit Deprez, M. in 't Veld.
    Lekanne, B. - \ 1992
    Landbouwkundig Tijdschrift 103 (1992)11. - ISSN 0927-6955 - p. 8 - 10.
    Silvopastorale gebieden als sociale ruimte bij de Mossi van Burkina Faso.
    Lekanne, B. - \ 1992
    Unknown Publisher - 16 p.
    The management of forestry resources in the Sahel.
    Lekanne dit Deprez, B.E.J.C. - \ 1990
    London : ODI - 23 p.
    Rapport de mission d'evaluation du projet bois de villages, Segou.
    Diakite, S. ; Diarra, M. ; Lekanne dit Deprez, B. ; Geerling, C. - \ 1987
    Unknown Publisher - 47 p.
    Ecologie in antropologie en sociologie.
    Lekanne dit Deprez, B. - \ 1986
    IMWOO Bulletin 14 (1986)4. - ISSN 0169-5711 - p. 19 - 21.
    Les terres noires de la Province du Mono: grenier neglige?
    Lekanne dit Deprez, B.E.J.C. - \ 1983
    Unknown Publisher
    Interdisciplinaire samenwerking: hoe zinvol onderscheid te maken
    Lekanne dit Deprez, B.E.J.C. - \ 1983
    IMWOO Bulletin 11 (1983)4. - ISSN 0169-5711 - p. 14 - 17.
    Sociology and public policy-making: An essay on the limited role of sociological knowledge in shaping public policies
    Lekanne dit Deprez, B.E.J.C. - \ 1981
    In: Essays in rural sociology : in honour of R.A.J. van Lier Wageningen : Agricultural University - p. 125 - 150.
    Landevaluatie, een grondig instrument
    Lekanne dit Deprez, B.E.J.C. - \ 1980
    Landbouwkundig Tijdschrift 92 (1980)2. - ISSN 0927-6955 - p. 34 - 34.
    Platteland met een gat erin
    Lekanne dit Deprez, B.E.J.C. - \ 1977
    Landbouwkundig Tijdschrift 88 (1977). - ISSN 0927-6955 - p. 87 - 87.
    Werkboek Inleiding analytische demografie voor de ontwikkelingslanden
    Lekanne dit Deprez, B.E.J.C. - \ 1976
    Unknown Publisher
    Speciaal aangepaste technologie: wie heeft zich aan te passen?
    Lekanne dit Deprez, B.E.J.C. - \ 1976
    Landbouwkundig Tijdschrift 88 (1976). - ISSN 0927-6955 - p. 89 - 89.
    Macht en onmacht van interdisciplinair samenwerken
    Lekanne dit Deprez, B.E.J.C. - \ 1976
    Intermediair 12 (1976). - ISSN 0020-5605
    Land and peasants in Imperial Ethiopia
    Lekanne dit Deprez, B.E.J.C. - \ 1976
    Sociologia Ruralis 16 (1976)3. - ISSN 0038-0199 - p. 335 - 336.
    De vrouw en de plattelandsontwikkeling in de tropen
    Lekanne dit Deprez, B.E.J.C. - \ 1976
    Landbouwkundig Tijdschrift 88 (1976). - ISSN 0927-6955 - p. 384 - 385.
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