Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Voedingsopleiding volgt ontwikkelingen in de wetenschap
Raaij, J.M.A. van; Marteijn, R.C.L. ; Pepping, F. - \ 2008
Voeding Nu 10 (2008)12. - ISSN 1389-7608 - p. 10 - 12.
voedselwetenschappen - voedingsonderwijs - universitaire onderwijsprogramma's - voedingsonderzoek - humane voeding - food sciences - dietetic education - college programs - nutrition research - human feeding
In 40 jaar is veel gebeurd in het wetenschappelijk voedingsonderwijs in Wageningen. Een overzicht van de veranderingen
Onderzoek naar een optimaal algendieet voor kunstmatig gekweekte mossellarven (Mytilus edulis)
Marteijn, E.H. - \ 2007
Yerseke : IMARES (Rapport / Wageningen, Institute for Marine Resources & Ecosystem Studies (IMARES) nr. 07.008) - 73
mytilus edulis - mossels - mosselteelt - algen - voedering - mussels - mussel culture - algae - feeding
Om tekorten aan mosselzaad aan te vullen hebben mosselvissers zaad geïmporteerd uit Ierland en zijn er mosselzaadinvanginstallaties uitgehangen. Een andere oplossing om het tekort aan te vullen is het kunstmatig kweken van mosselen. Het voedselaanbod bestaat uit fytoplankton, namelijk flagellaten en diatomeeën. Het doel van een hatchery is een hoge groeisnelheid met een hoog overlevingspercentage zien te bereiken
Optimization of a feed medium for fed-batch culture of insect cells using a genetic algorithm
Marteijn, R.C.L. ; Jurrius, O. ; Dhont, J. ; Gooijer, C.D. de; Tramper, J. ; Martens, D.E. - \ 2003
Biotechnology and Bioengineering 81 (2003)3. - ISSN 0006-3592 - p. 269 - 278.
recombinant protein-production - serum-free medium - expression vector system - sf-9 cells - baculovirus - growth - density - design - yield - improvement
Insect cells have been cultured for over 30 years, but their application is still hampered by low cell densities in batch fermentations and expensive culture media. With respect to the culture method, the fed-batch culture mode is often found to give the best yields. However, optimization of the feed composition is usually a laborious task. In this report, the successful use of genetic algorithms (GAs) to optimize the growth of insect cells is described. A feed was developed from 11 different medium components, each used at a wide range of concentrations. The feed was optimized within four sets of 20 experiments. The optimized feed was tested in bioreactors and the addition scheme was further improved. The viable-cell density of HzAm1 (Helicoverpa zea) insect cells improved 550% to 19.5 × 106 cells/mL compared to a control fermentation in an optimized commercial medium. No accumulation of waste products was found, and none of the amino acids was depleted. Glucose was depleted, which suggests that even further improvement is possible. We show that GAs are a successful method to optimize a complex fermentation in a relatively short time frame and without the need of detailed information concerning the cellular physiology or metabolism
Hydraulische en sedimentaire processen in de anastomoserende bovenloop van de Columbia River
Makaske, B. - \ 2001
In: NCR-dagen 2000, het begin van een nieuwe reeks / Wolters, A.F., Sloff, C.J., Marteijn, E.C.L.,
Application of an accelaration-stat to study insect cell metabolism
Marteijn, R. ; Oude Elferink, M. ; Bron, R. ; Martens, D. ; Tramper, J. - \ 2001
In: Animal Cell Technology: From Target to Market : 17th ESACT Meeting, Tylösand, Sweden / Lindner-Olsson, E., Chatzissavidou, N., Lüllau, E., Dordrecht : Kluwer Academic Publishers - p. 274 - 276.
Visie onderzoek rivieren Alterra; deelvisie onderzoeksprogramma NCR
Harms, W.B. ; Jonge, J.M. de; Pedroli, G.B.M. ; Oost, L. ; Querner, E.P. ; Wolfert, H.P. - \ 2000
In: De weg van maatschappelijke vraag naar onderzoek / Wolters, A.F., Marteijn, E.C.L., - p. 24 - 32.
Inrichting rivierengebied
Leuven, R.S.E.W. ; Wolfert, H.P. - \ 2000
In: De weg van maatschappelijke vraag naar onderzoek / Wolters, A.F., Marteijn, E.C.L., - p. 46 - 52.
Effect of low inoculation density in the scale-up of insect cell cultures
Marteijn, R.C.L. ; Oude Elferink, M.M.A. ; Martens, D.E. ; Gooijer, C.D. de; Tramper, J. - \ 2000
Biotechnology Progress 16 (2000). - ISSN 8756-7938 - p. 795 - 799.
The scale-up of insect cell cultures and the production of baculovirus with these cultures is dependent on the inoculation density applied. The effect of applying a low inoculation on the specific growth rate and on the duration of the lag phase was tested. Three different cell lines, HzAm1, Ha2302, and Sf21 were tested in a total of five cell line/medium combinations. Growth in suspension culture was examined, and data obtained were fitted with the Gompertz equation. A significant decline in specific growth rate with decreasing inoculation density was observed in all cell line/medium combinations, except for HzAm1. No critical inoculation density, below which no growth would occur, was found. In suspension culture in shake flasks, an inoculation density of 5 x 104 cells/mL is achievable, without severely influencing the overall growth rate. A lower inoculation density in suspension culture results in less steps in the scale-up process and might be a tool in bypassing the viral passage effect.
Ecological networks in river rehabilitation scenarios: Rhine-Econet; summary report
Wolfert, H.P. ; Harms, W.B. ; Marteijn, E.C.L. ; Reijnen, R. - \ 1996
Lelystad : RIZA - ISBN 9789036945677 - 24
ecosystemen - herstel - natuurtechniek - natuur - rijn - ecosystems - rehabilitation - ecological engineering - nature - river rhine
The significance of an ecological network of natural areas for a successful nature conservation and rehabilitation strategy of the Lower Rhine between Gorinchem (Netherlands) and Duisburg (Germany) is indicated. A scenario approach is used to illuminate variations in the planning of 10 000 ha of new natural areas, focused on riverine forest, macrophyte marsh and side channels. Each scenario is evaluated by determining its network function for nine characteristic fauna species. The results can serve as a conceptual framework for decisions on the ecological future of the Lower Rhine and probably also for other European rivers.
Ecological rehabilitation of the rivers Rhine and Meuse: summary report 1994-1995
Hendriks, A.J. ; Cals, M.J.R. ; Cazemier, W.G. ; Dijk, G.M. van; Higler, L.W.G. ; Marteijn, E.C.L. ; Pieters, H. ; Postma, R. ; Wolfert, H.P. - \ 1996
Unknown Publisher - 36 p.
Functional analysis of the putative transposase gene t32A of the CpGV-integrated transposon TCp3.2.
Jehle, J.A. ; Marteijn, R.C.L. ; Vlak, J.M. - \ 1996
In: Abstract 15th Annual meeting of the American Society for Virology, London, Ontario, Canada - p. 114 - 114.
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