Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Chemische en fysische gevaren in de Nederlandse diervoederketen
    Fels-Klerx, H.J. van der; Asselt, E.D. van; Adamse, P. ; Nijkamp, M.N. ; Leeuwen, S.P.J. van; Pikkemaat, M. ; Nijs, M. de; Mol, H. ; Raamsdonk, L. van; Hoogenboom, R. ; Jong, J. de - \ 2019
    Wageningen : RIKILT Wageningen University & Research (RIKILT report 2019.002) - 85
    Chemische en fysische gevaren in de Nederlandse aardappelketen
    Nijkamp, M.M. ; Asselt, E.D. van; Janssens, B. ; Razenberg, L. ; Wit-Bos, L. de; Fels-Klerx, H.J. van der - \ 2017
    Wageningen : RIKILT Wageningen University & Research (Rikilt rapport 2017.010) - 91
    Sustainability and agri-environmental policy in the European Union : A meta-analytic investigation
    Oltmer, Katrin ; Nijkamp, Peter ; Florax, Raymond ; Brouwer, Floor - \ 2016
    In: Traditional Food Production and Rural Sustainable Development / de Noronha Vaz, T., Nijkamp, P., Taylor and Francis - ISBN 9780754674627 - p. 27 - 55.
    The world olive oil market has experienced dramatic changes during the last decade which have resulted, inter alia, in the rapid quantitative and qualitative expansion of world supply and demand, and a significant intensification of horizontal and vertical competition along the product's marketing chain. The European Union (EU) is the major participant in the international olive oil market, accounting for 80 per cent of world production, 70 per cent of world consumption, and 50 per cent of world trade. The available information indicates that the future competitive scenario for EU olive oil will be shaped principally by two types of factors: the market dynamics and business strategies; and the ongoing agricultural and trade policy reform processes. Methodology research uses the Strengths-Weaknesses-Opportunities-Threats (SWOT) technique which is a common tool for the evaluation of economic and policy processes. The EU olive oil industry also has to adopt strategies in order to face its weaknesses and vulnerabilities.
    Regionalising Input-Output Tables: Comparison of Four Location Quotiënt Methods
    Klijs, J. ; Peerlings, J.H.M. ; Steijaert, Tim ; Heijman, Wim - \ 2016
    In: Impact Assessment in Tourism Economics / Matias, Alvaro, Nijkamp, Peter, Romao, Joao, Springer - ISBN 9783319149196 - p. 43 - 65.
    In this chapter we compare four methods to generate a regional input-output table (RIOT). A RIOT is a requirement for a regional input-output (IO) analysis and any over- or underestimation of regional input-output coefficients (RIOCs), contained in the RIOT, can lead to over- or underestimation of economic impacts. One category of methods that can be used to generate a RIOT is based on location quotients (LQs). When the choice is made to apply an LQ method, the researcher must decide which one to use, as several alternatives are available. In this chapter we establish a ranking in size of RIOCs, generated by the four most used LQ methods (Simple Location Quotient, Cross Industry Location Quotient, Round’s Location Quotient, and Flegg’s Location Quotient). This ranking shows if, for any combination of demanding and supplying sectors, the use of a different LQ method would lead to smaller or larger RIOCs. We also derive a ranking in size of total output multipliers. We conclude that this ranking is not necessarily the same as the ranking in size of RIOCs. Although our analysis is relevant for any regional economic impact analysis, the relevance for tourism is especially prevalent as IO analysis is commonly used in this domain, for reasons of data availability, comparability, and simplicity.
    Chromosomal copy number variation in Saccharomyces pastorianus is evidence for extensive genome dynamics in industrial lager brewing strains
    Broek, M. van den; Bolat, I. ; Nijkamp, J.F. ; Ramos, E. ; Luttik, M.A.H. ; Koopman, F. ; Geertman, J.M. ; Ridder, D. de; Pronk, J.T. ; Daran, J.M. - \ 2015
    Applied and Environmental Microbiology 81 (2015)18. - ISSN 0099-2240 - p. 6253 - 6267.

    Lager brewing strains of Saccharomyces pastorianus are natural interspecific hybrids originating from the spontaneous hybridization of Saccharomyces cerevisiae and Saccharomyces eubayanus. Over the past 500 years, S. pastorianus has been domesticated to become one of the most important industrial microorganisms. Production of lager-type beers requires a set of essential phenotypes, including the ability to ferment maltose and maltotriose at low temperature, the production of flavors and aromas, and the ability to flocculate. Understanding of the molecular basis of complex brewing-related phenotypic traits is a prerequisite for rational strain improvement. While genome sequences have been reported, the variability and dynamics of S. pastorianus genomes have not been investigated in detail. Here, using deep sequencing and chromosome copy number analysis, we showed that S. pastorianus strain CBS1483 exhibited extensive aneuploidy. This was confirmed by quantitative PCR and by flow cytometry. As a direct consequence of this aneuploidy, a massive number of sequence variants was identified, leading to at least 1,800 additional protein variants in S. pastorianus CBS1483. Analysis of eight additional S. pastorianus strains revealed that the previously defined group I strains showed comparable karyotypes, while group II strains showed large interstrain karyotypic variability. Comparison of three strains with nearly identical genome sequences revealed substantial chromosome copy number variation, which may contribute to strain-specific phenotypic traits. The observed variability of lager yeast genomes demonstrates that systematic linking of genotype to phenotype requires a three-dimensional genome analysis encompassing physical chromosomal structures, the copy number of individual chromosomes or chromosomal regions, and the allelic variation of copies of individual genes.

    Greenhouse gas emissions in The Netherlands 1990-2012; National inventory report 2014
    Coenen, P.W.H.G. ; Maas, C.W.M. ; Zijlema, P.J. ; Arets, E.J.M.M. ; Baas, K. ; Berghe, A.C.W.M. van den; Biesebeek, J.D. te; Nijkamp, M.M. ; Huis, E.P. - \ 2014
    Bilthoven : RIVM - 278
    broeikasgassen - emissie - kooldioxide - methaan - inventarisaties - nederland - greenhouse gases - emission - carbon dioxide - methane - inventories - netherlands
    Total greenhouse gas emissions from the Netherlands in 2012 decreased by approximately 1.7 per cent, compared with 2011 emissions. This decrease is mainly the result of decreased fuel combustion in the Energy sector (increased electricity import) and in road transport. In 2012, total direct greenhouse gas emissions (excluding emissions from LULUCF – land use, land use change and forestry) in the Netherlands amounted to 191.7 Tg CO2 eq. This is approximately 10 per cent below the emissions in the base year (213.2 Tg CO2 eq.). The 51% reduction in the non-CO2 emissions in this period is counterbalanced by 4 per cent increase in CO2 emissions since 1990.This report documents the Netherlands’ 2014 annual submission of its greenhouse gas emissions inventory in accordance with the guidelines provided by the United Nations Framework Convention on Climate Change (UNFCCC), the Kyoto Protocol and the European Union’s Greenhouse Gas Monitoring Mechanism.The report comprises explanations of observed trends in emissions; a description of an assessment of key sources and their uncertainty; documentation of methods, data sources and emission factors applied; and a description of the quality assurance system and the verification activities performed on the data.Keywords: greenhouse gases, emissions, trends, methodology, climate.
    De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology
    Nijkamp, J.F. ; Broek, M. van den; Datema, E. ; Kok, S. de; Bosman, L. ; Luttik, M.A. ; Daran-Lapujade, P. ; Vongsangnak, W. ; Nielsen, J. ; Heijne, W.H.M. ; Klaassen, P. ; Paddon, C.J. ; Platt, D. ; Kotter, P. ; Ham, R.C.H.J. van; Reinders, M.J.T. ; Pronk, J.T. ; Ridder, D. de; Daran, J.M. - \ 2012
    Microbial Cell Factories 11 (2012). - ISSN 1475-2859
    l-arabinose - alcoholic fermentation - biotin-prototrophy - chemostat cultures - gene prediction - yeast genome - glucose - evolutionary - protein - xylose
    Saccharomyces cerevisiae CEN.PK 113-7D is widely used for metabolic engineering and systems biology research in industry and academia. We sequenced, assembled, annotated and analyzed its genome. Single-nucleotide variations (SNV), insertions/deletions (indels) and differences in genome organization compared to the reference strain S. cerevisiae S288C were analyzed. In addition to a few large deletions and duplications, nearly 3000 indels were identified in the CEN.PK113-7D genome relative to S288C. These differences were overrepresented in genes whose functions are related to transcriptional regulation and chromatin remodelling. Some of these variations were caused by unstable tandem repeats, suggesting an innate evolvability of the corresponding genes. Besides a previously characterized mutation in adenylate cyclase, the CEN. PK113-7D genome sequence revealed a significant enrichment of non-synonymous mutations in genes encoding for components of the cAMP signalling pathway. Some phenotypic characteristics of the CEN. PK113-7D strains were explained by the presence of additional specific metabolic genes relative to S288C. In particular, the presence of the BIO1 and BIO6 genes correlated with a biotin prototrophy of CEN. PK113-7D. Furthermore, the copy number, chromosomal location and sequences of the MAL loci were resolved. The assembled sequence reveals that CEN. PK113-7D has a mosaic genome that combines characteristics of laboratory strains and wild-industrial strains.
    Broilers with Taste - Sustainable chicken takes flight
    Janssen, A.P.H.M. ; Nijkamp, R. ; Geloof, E. van; Ruth, J. van; Kemp, H. ; Bos, A.P. - \ 2011
    Wageningen : Wageningen UR Livestock Research - ISBN 9789461732644 - 17
    pluimveehouderij - vleeskuikens - huisvesting van kippen - dierenwelzijn - duurzame veehouderij - duurzaamheid (sustainability) - vleeskuikenproductie - kippenvlees - poultry farming - broilers - chicken housing - animal welfare - sustainable animal husbandry - sustainability - broiler production - chicken meat
    Engelse versie van de brochure 'Pluimvee met smaak : duurzame kip krijgt vleugels', die laat zien waar kansen liggen voor de Nederlandse pluimveesector om te verduurzamen. Twee uiteenlopende concepten, de Som der Delen en de Windstreek, geven ieder op eigen wijze invulling aan duurzaamheid op het primaire bedrijf. Ze bevatten belangrijke elementen voor verduurzaming, die als geheel of in onderdelen, nu of later, in de praktijk gebracht kunnen worden. Duurzaamheid kent immers niet één, maar vele vormen, afhankelijk van de ondernemers, de markt en de omgeving.
    Pluimvee met smaak : duurzame kip krijgt vleugels
    Janssen, A.P.H.M. ; Nijkamp, R. ; Geloof, E. van; Ruth, J. van; Kemp, H. ; Bos, A.P. - \ 2011
    Lelystad : Livestock Research, Wageningen UR - ISBN 9789461731715
    pluimveehouderij - vleeskuikens - huisvesting van kippen - dierenwelzijn - duurzame veehouderij - duurzaamheid (sustainability) - vleeskuikenproductie - kippenvlees - poultry farming - broilers - chicken housing - animal welfare - sustainable animal husbandry - sustainability - broiler production - chicken meat
    Deze brochure laat zien waar kansen liggen voor de Nederlandse pluimveesector om te verduurzamen. Twee uiteenlopende concepten, de Som der Delen en de Windstreek, geven ieder op eigen wijze invulling aan duurzaamheid op het primaire bedrijf. Ze bevatten belangrijke elementen voor verduurzaming, die als geheel of in onderdelen, nu of later, in de praktijk gebracht kunnen worden. Duurzaamheid kent immers niet één, maar vele vormen, afhankelijk van de ondernemers, de markt en de omgeving.
    Changes on raw bovine milk composition across the season
    Roca-Fernández, A.I. ; Nijkamp, R. ; Valenberg, H.J.F. van; González-Rodriguez, A. ; Elgersma, A. - \ 2010
    In: Book of Abstracts of the 61st Annual Meeting of the European Association for Animal Production, Heraklion, Greece, 23-27 August 2010. - European Grassland Federation EGF - p. 168 - 168.
    Vitaal tuinbouwcluster 2040 : een toekomststrategie voor Greenport Holland
    Nijkamp, P. ; Huirne, R.B.M. ; Noordzij, K. ; Priemus, H. ; Roo, G. de; Knijff, A. van der - \ 2010
    [S.l. : S.n. - 27
    tuinbouw - tuinbouwbedrijven - concentratie van de productie - agrarische planning - agrarische economie - bedrijfsontwikkeling in de landbouw - ruimtelijke ordening - regionale ontwikkeling - regionaal landbouwbeleid - glastuinbouw - limburg - strategisch management - toekomst - horticulture - market gardens - concentration of production - agricultural planning - agricultural economics - farm development - physical planning - regional development - regional agricultural policy - greenhouse horticulture - limburg - strategic management - future
    Rapport van de commissie Tuinbouwcluster over de toekomst van Nederland als internationale Greenport.
    Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: Future therapeutic targets
    Kraneveld, A.D. ; Rijnierse, A. ; Nijkamp, F.P. ; Garssen, J. - \ 2008
    European Journal of Pharmacology 585 (2008)2-3. - ISSN 0014-2999 - p. 361 - 374.
    tumor-necrosis-factor - gene-related peptide - vasoactive-intestinal-peptide - enteric nervous-system - dorsal-root ganglion - toll-like receptors - primary nociceptive neurons - tachykinin nk2 receptors - colonic epithelial-cells - primary sensory neurons
    The gastro-intestinal tract is well known for its largest neural network outside the central nervous system and for the most extensive immune system in the body. Research in neurogastroenterology implicates the involvement of both enteric nervous system and immune system in symptoms of inflammatory bowel disease and irritable bowel syndrome. Since both disorders are associated with increased immune cell numbers, nerve growth and activation of both immune cells and nerves, we focus in this review on the involvement of immune cell-nerve interactions in inflammatory bowel disease and irritable bowel syndrome. Firstly, the possible effects of enteric nerves, especially of the nonadrenergic and noncholinergic nerves, on the intestinal immune system and their possible role in the pathogenesis of chronic intestinal inflammatory diseases are described. Secondly, the possible effects of immunological factors, from the innate (chemokines and Toll-like receptors) as well as the adaptive (cytokines and immunoglobulins) immune system, on gastro-intestinal nerves and its potential role in the development of inflammatory bowel disease and irritable bowel syndrome are reviewed. investigations of receptor-mediated and intracellular signal pathways in neuro-immune interactions might help to develop more effective therapeutic approaches for chronic inflammatory intestinal diseases.
    Ports in International Networks: A Multicriteria Evaluation of Policy Options for Accommodating Growth
    Vreeker, R. ; Nijkamp, P. ; Ansem, I. van; Ierland, E.C. van - \ 2008
    In: Network Strategies in Europe / Giaoutzi, Maria, Nijkamp, Peter, Aldershot, Hampshire : Ashgate Publishing Limited (Ashgate Economic Geography Series ) - ISBN 9780754673309 - p. 239 - 258.
    Multi-Agent Systems: a Tool in Spatial Planning; An Example of Micro-Simulation Use in Retail Development
    Leeuwen, E.S. van; Hagens, J.E. ; Nijkamp, P. - \ 2007
    DISP 43 (2007)3. - ISSN 0251-3625 - p. 19 - 32.
    Impactos medioambientales de la política agroambiental en la Unión Europea: una investigación meta-analitica
    Oltmer, K. ; Nijkamp, P. ; Florax, R.J.G.M. ; Brouwer, F.M. - \ 2006
    In: Una nueva cultura del territorio: criterios sociales y ambientales en las políticas y el gobierno del territorio / Tarroja, A., Camagni, R., Barcelona : Diputació de Barcelona - ISBN 9788498030808 - p. 351 - 384.
    Transport-related fringe benefits: implications for moving and the journey to work
    Ommeren, Jos van; Vlist, A.J. van der; Nijkamp, Peter - \ 2006
    Journal of Regional Science 46 (2006)3. - ISSN 0022-4146 - p. 493 - 506.
    residential-mobility - labor-markets - job search
    Firms offer compensation not only through wages, but also offer transport-related fringe benefits such as transport benefits (company cars, travel, and parking benefits) and relocation benefits to job applicants. We argue that these benefits are not randomly offered to employees, but depend on the job applicants' commuting costs. The firms' choice between these benefits affects the workers' incentive to move their residence closer to the workplace. Using information on firms' recruitment behavior in the United Kingdom, this paper shows empirically that the applicants' journey-to-work time induces firms to offer these benefits to job applicants. The implications of transport-related fringe benefits for commuting and relocation are found to be rather distinct. Transport benefits make employees less sensitive to the costs of commuting, whereas relocation benefits induce employees to move closer to the workplace.
    The Economics of Agricultural Land Use
    Oltmer, K. ; Nijkamp, P. - \ 2005
    In: Contemporary issues in urban and regional economics / Yee, L., New York : Nova Science Publishers - ISBN 9781594543036 - 185 p.
    The Regional Self-organizing Potential in Sustainable Agriculture: An Analysis of Co-operative Agreements on Pollution in Bavaria by Means of Rough Set Methods
    Nijkamp, P. ; Oltmer, K. - \ 2005
    Zeitschrift fur Umweltpolitik und Umweltrecht 2005 (2005)4. - ISSN 0931-0983 - p. 441 - 468.
    This study addresses the achievements of cooperative agreements in sustainable agriculture policy. After an economic analysis of multi-actor choice situations, it focuses the attention on the self-organizing potential of regional market parties in order to comply with environmental policy objectives. The empirical application concerns voluntary agreements among farmers in Bavaria regarding intensified efforts to reduce nitrate pollution of drinking water. By means of new variants of artificial intelligence methods based on rough set analysis, a systematic investigation of success factors of such strategies is achieved
    Living in Two Worlds: A Review of Home-to-Work Decisions
    Rouwendal, J. ; Nijkamp, P. - \ 2004
    Growth and Change 35 (2004)3. - ISSN 0017-4815 - p. 287 - 303.
    spatial job search - travel-time - labor-markets - urban model - los-angeles - wasteful - location - congestion - employment - choice
    This paper discusses various aspects of the economic analysis of commuting behavior. It starts with a review of two difficulties associated with urban economics models: the empirically falsified prediction of the relation between commuting time and income, and the presence of substantial excess commuting. Notwithstanding these anomalies, research that focuses directly on the value of travel time provides evidence that there is substantial resistance against commuting among large groups of workers. However, commuting costs are just one among many other explanatory variables for actual commuting behavior, and commuting itself has become much less onerous over time. This suggests that commuting costs play a much more limited role than has been assumed in the past. On the other hand, empirical evidence suggests that space is more important than one would be inclined to think on the basis of the considerations just given. These empirical regularities suggest that other space-related aspects of the functioning of urban labor and housing markets are more important than was previously thought
    Dual Earners, Urban Labour Markets and Housing Demand
    Rouwendal, J. ; Straaten, Willemijn - \ 2004
    In: Urban Dynamics and Growth (Contribution to Economic Analysis) / Peter Nijkamp Roberta Capello, and, Amsterdam : Elsevier (Contributions to Economic Analysis 266) - ISBN 9780444514813 - p. 249 - 283.
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