Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

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    Delfstofwinning en natuur
    Vliegenthart, Albert ; Zee, Friso van der - \ 2018
    Wageningen : Wageningen Environmental Research (Wageningen Environmental Research rapport 2873) - 95
    Het belang van stadsnatuur
    Snep, R.P.H. ; Zwarte, N. de; Graaf, Maaike de; Vergeer, P. ; Vliegenthart, A. ; Schimmel, I. - \ 2016
    De Levende Natuur 117 (2016)4. - ISSN 0024-1520 - p. 169 - 170.
    Meer vlinders door tijdelijke natuur
    Vliegenthart, A. ; Veling, K. - \ 2011
    Wageningen : Nature Today
    Derivation of Threshold Values for Groundwater in Romania, in order to distinguish Point & Diffuse pollution from natural background levels
    Schipper, P.N.M. ; Radu, E. ; Vliegenthart, F. ; Balaet, R. - \ 2010
    Environmental Engineering Research 15 (2010)2. - ISSN 1226-1025 - p. 85 - 91.
    Romania aims to adopt and implement the European Union's legislation, also including that for the field of water management. Like other countries, groundwater in Romania is locally polluted from point sources, such as leaking landfills, as well as from diffuse pollution sources, include fertilizers, pesticides and leakages from sewers, in urbanized areas. Diffuse pollution can also occur indirectly, by over-exploitation of groundwater wells, resulting in salt water intrusion, as well as from mining and exploitation of mineral aggregates. Romania has quite an intensive monitoring scheme to measure groundwater quality in phreatic and confined aquifers. The purpose of the work resumed in this paper was to derive natural background levels (NBL) for groundwater in order to distinguish the natural elevated concentrations of some substances (natural phenomena) from point and diffuse pollution (anthropogenic phenomena). Based on these NBLs, threshold values (TV) for groundwater will be set according to the requirements of the European Water Framework Directive and the related Groundwater Directive. This paper describes the results of a study for the derivation of NBL and TV in a pilot Groundwater Body. Also, the process and draft results for extrapolating this work for all Romanian groundwater bodies is explained, as well as points for future consideration with respect to monitoring and management.
    Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study
    Heine-Bröring, R.C. ; Brouwer, I.A. ; Vliegenthart, P.R. ; Rooij, F.J.A. van; Hofman, A. ; Oudkerk, M. ; Witteman, J.C.M. ; Geleijnse, J.M. - \ 2010
    American Journal of Clinical Nutrition 91 (2010)5. - ISSN 0002-9165 - p. 1317 - 1323.
    artery calcium score - heart-disease - controlled-trial - cardiovascular-disease - computed-tomography - risk prediction - atherosclerosis - omega-3-fatty-acids - supplementation - metaanalysis
    Background: Epidemiologic and experimental data suggest a cardioprotective effect of n–3 (omega-3) fatty acids from fish [eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA)]. Objective: The objective was to examine the association of fish and EPA plus DHA intakes with coronary calcification in a general older population. Design: Diet was assessed between 1990 and 1993 by using a semiquantitative 170-item food-frequency questionnaire. Coronary calcification was assessed 7 y later by electron-beam computed tomography in 1570 asymptomatic cardiac subjects with complete dietary data (44% men, mean age of 64 y). Calcium scores according to Agatston's method were divided into 10 (no/minimal coronary calcification), 11–400 (mild/moderate calcification), and >400 (severe calcification). Prevalence ratios (PRs) for mild/moderate and severe calcification were obtained in categories of fish and EPA plus DHA intake. PRs were adjusted for age, sex, body mass index, diabetes mellitus, socioeconomic status, smoking, alcohol intake, physical activity, and dietary factors. Results: Subjects with a fish intake >19 g/d had a significantly lower prevalence of mild/moderate calcification (PR: 0.87; 95% CI: 0.78, 0.98; full model) than did subjects who consumed no fish. Subjects with a high fish intake also had a lower prevalence of severe calcification (PR: 0.88; 95% CI: 0.74, 1.04), which was borderline statistically significant. EPA plus DHA intake showed no significant associations (PR: 0.93 and 0.97, respectively; P > 0.05). Conclusions: We found a weak inverse association between fish intake and coronary calcification. If confirmed in other population-based studies, more research is warranted to determine which components in fish can inhibit vascular calcification.
    No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study
    Bröring, R.C. ; Brouwer, I.A. ; Vliegenthart, R. ; Rooij, F.J.A. van; Witteman, J.C. ; Geleijnse, J.M. - \ 2009
    Circulation 119 (2009)10. - ISSN 0009-7322 - p. E340 - P264.
    Background: Fish and EPA/DHA intake is inversely related to risk of CHD. The underlying mechanism for this cardioprotective effect, however, is not yet clear. Objective: To examine fish and EPA/DHA intake in relation to calcification of the coronary arteries in a general Dutch population. Methods: Coronary calcification was detected with electron beam computed tomography between 1997-2000 in 1,570 subjects who were free of CHD (44% male, mean age: 64 y). Severe calcification was defined as an Agatston score >400. Dietary intake, including fish consumed during dinner, lunch and between meals, was assessed in 1990-1993 with a semiquantitative FFQ. Prevalence ratios (PR) for severe calcification were obtained by log-binomial regression (reference: Agatston score =20 vs. 0 g/d was 0.98 (95% CI: 0.75-1.27) in men and 0.85 (0.57-1.28) in women. PR for EPA/DHA (upper vs. lower tertile) were 0.94 (0.74-1.19) in men and 1.11 (0.76-1.62) in women. Conclusion: Our data do not support a role for EPA/DHA in coronary calcification in a general older population with a low or moderate level of fish intake
    Coffee Consumption and Coronary Calcification in Elderly People: The Rotterdam Coronary Calcification Study
    Geleijnse, J.M. ; Woudenbergh, G.J. van; Vliegenthart, R. ; Witteman, J.C. - \ 2008
    Circulation 117 (2008)11. - ISSN 0009-7322 - p. e237, P130 - e237, P130.
    Background: Diet and lifestyle play an important role in the development of coronary heart disease (CHD). The role of coffee in the cardiovascular system is not yet clear. We examined whether coffee consumption was related to severe coronary calcification, a strong predictor for CHD morbidity and mortality. Methods: The relation coffee consumption with coronary calcification was examined in 1,570 elderly men and women without CHD who participated in the Rotterdam Study. Habitual coffee use was assessed with a semiquantitative food frequency questionnaire. Coronary calcification was detected with electron beam computed tomography. Severe calcification was quantified as an Agatson calcium score >400. Sex-specific odds ratios (ORs) with 95% confidence intervals (95% CI) were obtained by multivariable logistic regression, adjusted for age, smoking, body mass index, education, and intake of energy and alcohol. Results: In multivariable analysis, coronary calcification in women was significantly inversely associated both with moderate (>3 to 4 cups) and high (>4 cups) coffee consumption, compared with a daily intake of 3 cups or less (OR of 0.41 [95% CI: 0.25 to 0.65] and 0.54 [0.33 to 0.87], respectively). The association persisted after additional adjustment for intake of tea, fruit, meat, and saturated fat. No significant association was found in men. Conclusion: Coffee was inversely associated with coronary calcification in women, whereas in non-smoking men a direct association was observed. Further studies should clarify the role of gender in the relation between coffee and coronary calcification
    Coffee Consumption and Coronary Calcification: The Rotterdam Coronary Calcification Study
    Geleijnse, J.M. ; Woudenbergh, G.J. van; Vliegenthart, R. ; Witteman, J.C. - \ 2008
    Circulation 117 (2008)11. - ISSN 0009-7322 - p. e237(P11) - e237(P11).
    Background: Diet and lifestyle play an important role in the development of coronary heart disease (CHD). The role of coffee in the cardiovascular system is not yet clear. We examined whether coffee consumption was related to severe coronary calcification, a strong predictor for CHD morbidity and mortality. Methods: The relation coffee consumption with coronary calcification was examined in 1,570 elderly men and women without CHD who participated in the Rotterdam Study. Habitual coffee use was assessed with a semiquantitative food frequency questionnaire. Coronary calcification was detected with electron beam computed tomography. Sex-specific odds ratios (ORs) with 95% confidence intervals (95% CI) were obtained by multivariable logistic regression, adjusted for age, smoking, body mass index, education, and intake of energy and alcohol. Results: In multivariable analysis, coronary calcification in women was significantly inversely associated both with moderate and high coffee consumption, compared with a daily intake of 3 cups or less. The association persisted after additional adjustment for intake of tea, fruit, meat, and saturated fat. No significant association was found in men. Conclusion: Coffee was inversely associated with coronary calcification in women, whereas in non-smoking men a direct association was observed. Further studies should clarify the role of gender in the relation between coffee and coronary calcification
    Coffee Consumption and Coronary Calcification: The Rotterdam Coronary Calcification Study
    Woudenbergh, G.J. van; Vliegenthart, R. ; Rooij, F.J.A. van; Hofman, A. ; Oudkerk, M. ; Witteman, J.C.M. ; Geleijnse, J.M. - \ 2008
    Arteriosclerosis Thrombosis and Vascular Biology 28 (2008)5. - ISSN 1079-5642 - p. 1018 - 1023.
    food frequency questionnaire - heart-disease - myocardial-infarction - computed-tomography - risk-factors - follow-up - women - metaanalysis - tea - caffeine
    Background¿ The role of coffee in the cardiovascular system is not yet clear. We examined the relation of coffee intake with coronary calcification in a population-based cohort. Methods and Results¿ The study involved 1570 older men and women without coronary heart disease who participated in the Rotterdam Study. Coffee intake was assessed with a semiquantitative food frequency questionnaire. Coronary calcification was detected with electron beam computed tomography. Severe calcification was defined as an Agatson calcium score >400. Sex-specific odds ratios (ORs) with 95% confidence intervals (95% CI) were obtained by logistic regression with adjustment for age, smoking, body mass index, education, and intake of energy and alcohol. In multivariable analysis, coronary calcification in women was significantly reduced for moderate (>3 to 4 cups) and high (>4 cups) coffee intake, compared with a daily intake of 3 cups or less (OR of 0.41 [95% CI: 0.25 to 0.65] and 0.54 [0.33 to 0.87], respectively). The association persisted after additional adjustment for tea and other dietary confounders, and was not modified by smoking. A nonsignificant inverse relationship was also found in men who smoked, whereas in nonsmoking men a direct association was observed. Conclusion¿ The present study suggests a beneficial effect of coffee drinking against coronary calcification, particularly in women. More research is needed to confirm these findings and to clarify possible effect modification by gender and smoking. The relation of coffee intake with coronary calcification was examined in 1570 older Dutch subjects. In smoking and nonsmoking women, coffee intake was strongly inversely related to severe coronary calcification. In smoking men, however, a direct relationship was observed. The effect of coffee on coronary calcification, and the interaction with gender and smoking, warrant further study.
    Interaction between dry starch and plasticisers glycerol or ethylene glycol, measured by differential scanning calorimetry and solid state NMR spectroscopy
    Smits, A.L.M. ; Kruiskamp, P.H. ; Soest, J.J.G. van; Vliegenthart, J.F.G. - \ 2003
    Carbohydrate Polymers 53 (2003)4. - ISSN 0144-8617 - p. 409 - 416.
    potato starch - molecular-organization - thermoplastic starch - glass-transition - retrogradation - saccharides - mixtures - barley - bread - phase
    The interaction of crystalline amylose and of crystalline and amorphous amylopectin with the plasticisers glycerol or ethylene glycol in the absence of water was studied, by using differential scanning calorimetry (DSC) and solid state nuclear magnetic resonance (NMR) spectroscopy. Upon heating starch freshly mixed with plasticisers, a strong exothermal interaction enthalpy of ¿H¿35 J/g was detected by DSC. At room temperature glycerol interacts mainly with the amorphous starch regions, the interaction taking 8 days to reach equilibrium. For ethylene glycol the interaction is faster, taking four days to reach equilibrium, and the rate is not affected by crystallinity. Ethylene glycol interacts in a more ordered manner with amorphous than with crystalline material, resulting in a narrower ethylene glycol cross-polarisation magic angle spinning (CP/MAS) signal when equilibrium is reached at room temperature. Upon heating, more glycerol or ethylene glycol is immobilised, but in a less ordered manner than upon storage at room temperature. This results in a more intense, but broader plasticiser CP/MAS signal upon heating. Interaction in a more ordered manner probably implies interaction with more of the hydroxy groups of the plasticiser. The polysaccharide mobility is increased more when the plasticiser interacts in a more ordered manner, as observed by small starch signals in HP/DEC spectra.
    The influence of various small plasticisers and malto-oligosaccharides on the retrogradation of (partly) gelatinised starch
    Smits, A.L.M. ; Kruiskamp, P.H. ; Soest, J.J.G. van; Vliegenthart, J.F.G. - \ 2003
    Carbohydrate Polymers 51 (2003)4. - ISSN 0144-8617 - p. 417 - 424.
    glass-transition - chain-length - amylopectin retrogradation - crystalline-structure - gelatinization - amylose - release - gels - saccharides - stabilities
    Ageing of gelatinised and partly gelatinised potato starch and wheat starch were investigated in the presence of plasticisers with increasing size and number of OH groups (ethylene glycol, glycerol, threitol, xylitol, glucose, and for potato starch also maltose). The influences of these plasticisers and of granular remnants (ghosts) on recrystallisation were determined by using X-ray diffraction. Recrystallisation of potato starch samples in the presence of plasticisers resulted in crystallinity indices of 0.5. The largest reduction in potato starch recrystallisation is found for threitol (4 OH) and xylitol (5 OH). In the plasticiser range examined, the crystallisation inducing effect of granular potato starch remnants is reduced better when the plasticiser contains more OH groups. Wheat starch recrystallises to a lesser extent than potato starch, resulting in crystallinity indices of 0.4. The results for wheat starch do not show clear trends for the influences of plasticiser size and of ghosts. The difference in behaviour of the two starches is probably caused by wheat starch having shorter amylopectin chains. Resulting from these shorter amylopectin chains, the remaining structure in wheat starch ghosts may resemble A-type crystallinity, making it more difficult to form B-type crystals. Alternatively, the trends as found for potato starch may occur, but are less manifest for wheat starch, due to the lower total extent of recrystallisation. Solid state CP/MAS NMR spectra of the wheat starch samples containing ethylene glycol were obtained, in order to compare completely and partly gelatinised systems. The spectra were identical, confirming that the ghost structures do not influence wheat starch recrystallisation. Apparently, wheat starch ghosts do not act as nuclei for crystallisation. Similarly, the influence of various malto-oligosaccharides in combination with granular remnants (ghosts) was investigated on wheat starch ageing. Gelatinised and partly gelatinised wheat starch were plasticised with maltose, maltotriose, maltotetraose, maltopentaose or maltohexaose. This resulted in crystallinity indices of 0.2, with the largest reduction in recrystallisation for maltotriose and maltotetraose. No trend was found for the influence of ghosts. The presence of ghosts did not influence the 13C solid state HP/DEC NMR spectra. Less recrystallisation took place than with the previously mentioned smaller plasticisers that resulted in crystallinity indices of 0.4. The finding that maltose was able to reduce retrogradation better than glucose could be of practical importance.
    Development of a biocatalytic process for the production of c6-aldehydes from vegetable oils by soybean lipoxygenase and recombinant hydroperoxide lyase
    Noordermeer, M.A. ; Goot, W. van der; Kooij, A.J. van; Veldsink, J.W. ; Veldink, G.A. ; Vliegenthart, J.F.G. - \ 2002
    Journal of Agricultural and Food Chemistry 50 (2002)15. - ISSN 0021-8561 - p. 4270 - 4274.
    Volatile C6- and C9-aldehydes and alcohols are widely used as food flavors to reconstitute the "fresh green" odor of fruits and vegetables lost during processing. To meet the high demand for natural flavors, an efficient, cheap, and versatile biocatalytic process was developed to produce C6-aldehydes on a large scale. Vegetable oils were converted by soybean lipoxygenase and recombinant hydroperoxide lyase into hexanal and (2E)- or (3Z)-hexenal. In contrast to plant extracts, generally used as enzyme sources, high molar conversions were obtained with recombinant hydroperoxide lyase (50␏or hexanal and 26␏or hexenal formation), and no side products were formed. Furthermore, recombinant hydroperoxide lyase lacks isomerase activity, allowing production of (3Z)-hexenal, which could not be obtained in previously described processes. Recombinant hydroperoxide lyase is stable and can be stored at 4 C for 1 month without significant loss of activity.
    Alcohol consumption and risk of peripheral arterial disease : the Rotterdam Study
    Vliegenthart, R. ; Geleijnse, J.M. ; Hofman, A. ; Meijer, W.T. ; Rooij, F.J.A. van; Grobbee, D.E. ; Witteman, J.C.M. - \ 2002
    American Journal of Epidemiology 155 (2002)4. - ISSN 0002-9262 - p. 332 - 338.
    Moderate alcohol consumption is associated with a reduced risk of cardiovascular disease. Data on alcohol consumption and atherosclerosis are scarce. To determine the association between alcohol consumption and risk of peripheral arterial disease, the authors carried out a cross-sectional study (1990–1993) in the population-based Rotterdam Study among men and women aged 55 years or over. Data on alcohol consumption and peripheral arterial disease, as measured by the ankle/brachial blood pressure index, were available for 3,975 participants without symptomatic cardiovascular disease. Male drinkers consumed beer, wine, and liquor, while female drinkers consumed predominantly wine and fortified wine types. An inverse relation between moderate alcohol consumption and peripheral arterial disease was found in women but not in men. Because of residual confounding by smoking, analyses were repeated in nonsmokers. In nonsmoking men, odds ratios were 0.86 (95␌onfidence interval (CI): 0.46, 1.63) for daily alcohol consumption up to and including 10 g, 0.75 (95␌I: 0.37, 1.55) for 11–20 g, and 0.68 (95␌I: 0.35, 1.34) for more than 20 g, compared with nondrinking. In nonsmoking women, corresponding odds ratios were 0.65 (95␌I: 0.48, 0.87), 0.66 (95␌I: 0.42, 1.05), and 0.41 (95␌I: 0.21, 0.77), respectively. In conclusion, an inverse association between alcohol consumption and peripheral arterial disease was found in nonsmoking men and women.
    Structure evolution in amylopectin/ethylene glycol mixtures by H-bond formation and phase separation studied with dielectric relaxation spectroscopy
    Smits, A.L.M. ; Wubbenhorst, M. ; Kruiskamp, P.H. ; Soest, J.J.G. van; Vliegenthart, J.F.G. ; Turnhout, J. van - \ 2001
    The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical 105 (2001)24. - ISSN 1520-6106 - p. 5630 - 5636.
    The CDTA-soluble pectic substances from soybean meal are composed of rhamnogalacturonan and xylogalacturonan but not homogalacturonan
    Huisman, M.M.H. ; Fransen, C.T.M. ; Kamerling, J.P. ; Vliegenthart, J.F.G. ; Schols, H.A. ; Voragen, A.G.J. - \ 2001
    Biopolymers 58 (2001). - ISSN 0006-3525 - p. 279 - 294.
    Structural characteristics of pectic substances extracted from soybean meal cell walls (water unextractable solids) with a chelating agent-containing buffer (0.05M 1,2-diaminocyclohexane-N,N,N,N-tetraacetic acid (CDTA) and 0.05M NH4-oxalate in 0.05M NaOAc buffer) were studied. The arabinogalactans present as side chains to the rhamnogalacturonan backbone were largely removed by enzymatic hydrolysis using endo-galactanase, exo-galactanase, endo-arabinanase, and arabinofuranosidase B. The remaining pectic backbone appeared to be resistant to enzymatic degradation by pectolytic enzymes. After partial acid hydrolysis of the isolated pectic backbone, one oligomeric and two polymeric populations were obtained by size-exclusion chromatography. Monosaccharide and linkage analyses, enzymatic degradation, and NMR spectroscopy of these populations showed that the pectic substances in the original extract contain both rhamnogalacturonan and xylogalacturonan regions, while homogalacturonan is absent.
    The influence of plasticiser on the molecular organisation in dry amylopectin measured by differential scanning calorimetry and solid state nuclear magnetic resonance spectroscopy
    Kruiskamp, P.H. ; Smits, A.L.M. ; Soest van, J.J.G. ; Vliegenthart, J.F.G. - \ 2000
    Journal of Industrial Microbiology and Biotechnology 26 (2000)1-2. - ISSN 1367-5435 - p. 90 - 93.
    The interaction of crystalline and amorphous amylopectin with the plasticisers glycerol and ethylene glycol in the absence of water was studied with differential scanning calorimetry (DSC) and solid state NMR. At room temperature glycerol interacts mainly with the amorphous regions, while for ethylene glycol the amylopectin crystallinity does not effect the interaction. After heating the mixtures, an additional immobilisation of the plasticiser occurs.
    Studies on the structure of a lithium-treated soybean pectin : characteristics of the fragments and determination of the carbohydrate substituents of galacturonic acid
    Fransen, C.T.M. ; Haseley, S.R. ; Huisman, M.M.H. ; Schols, H.A. ; Voragen, A.G.J. ; Kamerling, J.P. ; Vliegenthart, J.F.G. - \ 2000
    Carbohydrate Research : an international journal 328 (2000). - ISSN 0008-6215 - p. 539 - 547.
    Origins of B-type crystallinity in glycerol-plasticised, compression-moulded potato starches
    Hulleman, S.H.D. ; Kalisvaart, M.G. ; Janssen, F.H.P. ; Feil, H. ; Vliegenthart, J.F.G. - \ 1999
    Carbohydrate Polymers 39 (1999)4. - ISSN 0144-8617 - p. 351 - 360.
    Synthesis of two hyaluronic-acid-related oligosaccharide 4-methoxyphenyl glycosides having a beta-D-glucuronic acid residue at the reducing end
    Halkes, K.M. ; Slaghek, T.M. ; Hypponen, T.K. ; Kamerling, J.P. ; Vliegenthart, J.F.G. - \ 1999
    Polish Journal of Chemistry 73 (1999)7. - ISSN 0137-5083 - p. 1123 - 1131.
    Synthesis of two hyaluronic-acid-related oligosaccharides, the 4-methoxyphenyl β-glycosides of β-D-GlcpA-(1→3)-β-D-GlcpNAc-(1→4)-D-GlcpA and β-D-GlcpA-(1→3)-β-D-GlcpNAc-(1→4)-β-D-GlcpA-(1→3)- β-D-GJcpNAc-(1→4)-D-GlcpA, is described. D-Glucopyranosyluronic acid residues were obtained by selective oxidation at C6 of corresponding D-glucopyranosyl residues after construction of the oligosaccharide backbones, using pyridinium dichromate and acetic anhydride.
    The influence of polyols on the molecular organization in starch-based plastics
    Smits, A.L.M. ; Hulleman, S.H.D. ; Soest, J.J.G. van; Feil, H. ; Vliegenthart, J.F.G. - \ 1999
    Polymers for advanced technologies 10 (1999)10. - ISSN 1042-7147 - p. 570 - 573.
    The effect of processing temperature and time on the B-type crystallinity of thermoplastic starch was studied by recording X-ray diffractograms of conditioned, compression molded starch systems containing glycerol and water as plasticizers at a ratio of 100:30:56 (w/w/w). Initial recrystallization, developed during molding, was investigated further on similar amorphous potato starch and potato amylopectin systems. The crystallinity prior to processing does not influence the recrystallization, though residual (granular) crystallinity, present due to incomplete melting, increases the total crystallinity. After molding at high temperatures (>160°C), amylose is mainly responsible for initial recrystallization in the B-type lattice. The observed degree of recrystallization, however, cannot be due to amylose crystallization alone. Amylose seems to serve as a nucleus for crystallization of amylopectin or amylose-amylopectin co-crystallization takes place. Thermally induced starch polysaccharide-glycerol interactions were investigated on mixtures of dried starch and glycerol using differential scanning calorimetry and solid-state nuclear magnetic resonance spectroscopy. An exothermal transition was observed after which the mobility of glycerol was decreased significantly. This indicated the development of a strong polysaccharide-glycerol interaction in the absence of water. Copyright
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