Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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    Zo kies je een gezonde en sociale hond
    Ruis, M.A.W. - \ 2019
    Wageningen : Wageningen University & Research - 21 p.
    animal welfare - pets - dogs - animal behaviour - animal housing - animal health - animal nutrition - animal breeding
    Deze interactieve brochure van Platform Fairfok geeft een overzicht van beschikbare informatie, diensten of producten van organisaties die zich actief inzetten voor de gezonde en sociale hond in Nederland.
    Learn how to set up a breeding programme | WURcast
    Komen, J. - \ 2019
    Wageningen : WURcast
    animal breeding - animal breeding methods - breeding programmes
    Animal breeding: the concept of inbreeding | WURcast
    Bijma, P. - \ 2019
    Wageningen : Centre for Genetic Resources and Animal Breeding and Genomics Group, Wageningen University and Research Centre
    inbreeding - animal breeding - alleles
    Inbreeding is the result of mating two related individuals. Related individuals are more alike genetically than non-related individuals because they share alleles.
    Hoe kies je de beste stieren voor je bedrijf?
    Hoving, A.H. ; Ducro, B.J. - \ 2019
    Wageningen : Centre for Genetic Resources, the Netherlands (CGN), Wageningen University & Research
    animal breeding - dairy cattle - genetics - teaching materials - intermediate vocational training - animal welfare - animal production - animal health
    Docentenhandleiding bij lesmateriaal ‘Hoe kies je de beste stieren voor je bedrijf?’ Powerpoint ‘Hoe kies je de beste stieren voor je bedrijf?’ Excel file ‘Een selectie van de stierenkaart’.
    Prospects of whole-genome sequence data in animal and plant breeding
    Binsbergen, Rianne van - \ 2017
    Wageningen University. Promotor(en): R.F. Veerkamp; F.A. Eeuwijk, co-promotor(en): M.P.L. Calus. - Wageningen : Wageningen University - ISBN 9789463431903 - 220
    next generation sequencing - dna sequencing - quantitative trait loci - cattle - genomics - solanum lycopersicum - animal breeding - plant breeding - next generation sequencing - dna-sequencing - loci voor kwantitatief kenmerk - rundvee - genomica - solanum lycopersicum - dierveredeling - plantenveredeling

    The rapid decrease in costs of DNA sequencing implies that whole-genome sequence data will be widely available in the coming few years. Whole-genome sequence data includes all base-pairs on the genome that show variation in the sequenced population. Consequently, it is assumed that the causal mutations (e.g. quantitative trait loci; QTL) are included, which allows testing a given trait directly for association with a QTL, and might lead to discovery of new QTL or higher accuracies in genomic predictions compared to currently available marker panels. The main aim of this thesis was to investigate the benefits of using whole-genome sequence data in breeding of animals and plants compared to currently available marker panels. First the potential and benefits of using whole-genome sequence data were studied in (dairy) cattle. Accuracy of genotype imputation to whole-genome sequence data was generally high, depending on the used marker panel. In contrast to the expectations, genomic prediction showed no advantage of using whole-genome sequence data compared to a high density marker panel. Thereafter, the use of whole-genome sequence data for QTL detection in tomato (S. Lycopersicum) was studied. In a recombinant inbred line (RIL) population, more QTL were found when using sequence data compared to a marker panel, while increasing marker density was not expected to provide additional power to detect QTL. Next to the RIL population, also in an association panel it was shown that, even with limited imputation accuracy, the power of a genome-wide association study can be improved by using whole-genome sequence data. For successful application of whole-genome sequence data in animals or plants, genotype imputation will remain important to obtain accurate sequence data for all individuals in a cost effective way. Sequence data will increase the power of QTL detection in RIL populations, association panels or outbred populations. Added value of whole-genome sequence data in genomic prediction will be limited, unless more information is known about the biological background of traits and functional annotations of DNA. Also statistical models that incorporate this information and that can efficiently handle large datasets have to be developed.

    Milk progesterone measures to improve genomic selection for fertility in dairy cows
    Tenghe, Amabel Manyu Mefru - \ 2017
    Wageningen University. Promotor(en): R.F. Veerkamp; B. Berglund, co-promotor(en): D. J. de Koning; A.C. Bouwman. - Wageningen : Wageningen University - ISBN 9789463431330 - 179
    dairy cows - fertility - progesterone - milk - genomics - genetic improvement - heritability - genetic parameters - dairy performance - reproductive traits - animal genetics - animal breeding - dairy farming - melkkoeien - vruchtbaarheid - progesteron - melk - genomica - genetische verbetering - heritability - genetische parameters - melkresultaten - voortplantingskenmerken - diergenetica - dierveredeling - melkveehouderij

    Improved reproductive performance has a substantial benefit for the overall profitability of dairy cattle farming by decreasing insemination and veterinary treatment costs, shortening calving intervals, and lowering the rate of involuntary culling. Unfortunately, the low heritability of classical fertility traits derived from calving and insemination data makes genetic improvement by traditional animal breeding slow. Therefore, there is an interest in finding novel measures of fertility that have a higher heritability or using genomic information to aid genetic selection for fertility. The overall objective of this thesis was to explore the use of milk progesterone (P4) records and genomic information to improve selection for fertility in dairy cows. In a first step, the use of in-line milk progesterone records to define endocrine fertility traits was investigated, and genetic parameters estimated. Several defined endocrine fertility traits were heritable, and showed a reasonable repeatability. Also, the genetic correlation of milk production traits with endocrine fertility traits were considerably lower than the correlations of milk production with classical fertility traits. In the next step 17 quantitative trait loci (QTL) associated with endocrine fertility traits, were identified on Bos taurus autosomes (BTA) 2, 3, 8, 12, 15, 17, 23, and 25 in a genome-wide association study with single nucleotide polymorphisms. Further, fine-mapping of target regions on BTA 2 and 3, identified several associated variants and potential candidate genes underlying endocrine fertility traits. Subsequently, the optimal use of endocrine fertility traits in genomic evaluations was investigated; using empirical and theoretical predictions for single-trait models, I showed that endocrine fertility traits have more predictive ability than classical fertility traits. The accuracy of genomic prediction was also substantially improved when endocrine and classical fertility traits were combined in multi-trait genomic prediction. Finally, using deterministic predictions, the potential accuracy of multi-trait genomic selection when combining a cow training population measured for the endocrine trait commencement of luteal activity (C-LA), with a training population of bulls with daughter observations for a classical fertility trait was investigated. Results showed that for prediction of fertility, there is no benefit of investing in a cow training population when the breeding goal is based on classical fertility traits. However, when considering a more biological breeding goal for fertility like C-LA, accuracy is substantially improved when endocrine traits are available from a limited number of farms.

    Selection for pure- and crossbred performance in Charolais
    Vallée-Dassonneville, Amélie - \ 2017
    Wageningen University. Promotor(en): Johan van Arendonk; Henk Bovenhuis. - Wageningen : Wageningen University - ISBN 9789463430180 - 151
    charolais - cattle - animal breeding - crossbreeding - crossbreds - selection - beef cattle - genomes - genetic parameters - charolais - rundvee - dierveredeling - kruisingsfokkerij - kruising - selectie - vleesvee - genomen - genetische parameters

    Two categories of beef production exist; i.e. (i) purebred animals from a beef sire and a beef dam and (ii) crossbred animals from a beef sire and a dairy dam.

    For the purebred beef production, there is a growing interest to include behavior and type traits in the breeding goal. Heritabilities for behavior traits, estimated using subjective data scored by farmers, range from 0.02 to 0.19. Heritabilities for type traits range from 0.02 to 0.35. Results show that there are good opportunities to implement selection for behavior traits using a simple on-farm recording system to allow collection of large data set, and for type traits in Charolais. A genome-wide association study detected 16 genomic regions with small effect on behavior and type traits. This suggests that behavior and type traits are influenced by many genes each explaining a small part of the genetic variance.

    The two main dairy breeds mated to Charolais sires for crossbred beef production in France are Montbéliard and Holstein. The genetic correlation between the same trait measured on Montbéliard x Charolais and on Holstein x Charolais was 0.99 for muscular development, 0.96 for birth weight; and 0.91 for calving difficulty, 0.80 for height, and 0.70 for bone thinness. Thus, for these last three traits, results show evidence for re-ranking of Charolais sires depending on whether they are mated to Montbéliard or Holstein cows. When using genomic prediction, the Montbéliard x Charolais and Holstein x Charolais populations could be combined into a single reference population to increase size and accuracy of genomic prediction. Results indicate that the higher the genetic correlation is between the two crossbred populations, the higher the gain in accuracy is achieved when combining the two populations into a single reference.

    The selection of Charolais sires to produce purebred or crossbred animals is made through distinct breeding programs. An alternative could be to combine selection into one breeding program. Decision for combining or keeping breeding programs separate is determined by the correlation between the breeding objectives, the selection intensity, the difference in level of genetic merit, the accuracy of selection, and the recent implementation of genomic evaluation. Considering all parameters and based on estimations for selection on birth weight, I recommend combining both breeding programs because this will lead to higher genetic gain, and might simplify operating organization and reduce associated costs.

    Genetische analyse van de Stabij
    Doekes, H.P. ; Oldenbroek, J.K. ; Windig, J.J. - \ 2016
    Zeldzaam huisdier 41 (2016)1. - ISSN 0929-905X - p. 18 - 19.
    zeldzame rassen - genetische analyse - hondenrassen - friese stabij - dierveredeling - rare breeds - genetic analysis - dog breeds - frisian stabyhoun - animal breeding
    De Stabij is een van de negen oorspronkelijke Nederlandse hondenrassen die een belangrijke rol vervullen in het Fairfok-programma van de Raad van Beheer voor de Kynologie. De SZH ondersteunt dat programma door de rasverenigingen van kennis en advies te voorzien en heeft met het CGN een genetische analyse gemaakt van het Stabijras.
    Genetische analyse van het Markiesje
    Doekes, H.P. ; Oldenbroek, J.K. ; Windig, J.J. - \ 2016
    Zeldzaam huisdier 41 (2016)2. - ISSN 0929-905X - p. 20 - 21.
    hondenrassen - zeldzame rassen - genetische analyse - dierveredeling - stamboeken - dog breeds - rare breeds - genetic analysis - animal breeding - herdbooks
    Het Markiesje is een van de negen oorspronkelijke Nederlandse hondenrassen. Het vervult een belangrijke rol in het Fairfok-programma. De SZH ondersteunt dat programma door de rasverenigingen van kennis en advies te voorzien.
    Leerstoelgroep Filosofie en Dier-ethiek Wageningen; '10.000 liter per koe is onethisch'
    Gremmen, Bart - \ 2016
    animal welfare - animal ethics - animal production - dairy cattle - cattle - animal breeding - animal health

    De melkveehouderij krijgt geregeld als kritiek dat ze dieronvriendelijk en onethisch werkt. Neem de kalf-bij-de-koediscussie. Het dier wordt steeds meer vermenselijkt, met als gevolg scheve veronderstellingen over dierethiek. Wageningse professor Bart Gremmen: „Het eten van dierlijke producten gaat altijd gepaard met dierenleed.”

    ‘Inteelt zie je niet altijd, maar kost wel geld’ : onderzoeker Nauta overweegt studieclub fokkerij op te zetten
    Windig, Jack - \ 2016
    inbreeding - inbreeding depression - goat keeping - animal breeding - farm management
    Fokken, wat is dat?
    Oldenbroek, Kor - \ 2016
    animal welfare - pets - dogs - animal health - animal behaviour - animal breeding - genetics
    Genomic selection in egg-laying chickens
    Heidaritabar, M. - \ 2016
    Wageningen University. Promotor(en): Martien Groenen, co-promotor(en): John Bastiaansen. - Wageningen : Wageningen University - ISBN 9789462576704 - 220
    hens - genomics - genetic variation - selective breeding - quantitative traits - breeding value - animal genetics - animal breeding - hennen - genomica - genetische variatie - selectief fokken - kwantitatieve kenmerken - fokwaarde - diergenetica - dierveredeling

    Abstract

    Heidaritabar, M. (2016). Genomic selection in egg-laying chickens. PhD thesis, Wageningen University, the Netherlands

    In recent years, prediction of genetic values with DNA markers, or genomic selection (GS), has become a very intense field of research. Many initial studies on GS have focused on the accuracy of predicting the genetic values with different genomic prediction methods. In this thesis, I assessed several aspects of GS. I started with evaluating results of GS against results of traditional pedigree-based selection (BLUP) in data from a selection experiment that applied both methods side by side. The impact of traditional selection and GS on the overall genome variation as well as the overlap between regions selected by GS and the genomic regions predicted to affect the traits were assessed. The impact of selection on genome variation was assessed by measuring changes in allele frequencies that allowed the identification of regions in the genome where changes must be due to selection. These frequency changes were shown to be larger than what could be expected from random fluctuations, indicating that selection is really affecting the allele frequencies and that this effect is stronger in GS compared with BLUP. Next, concordance was tested between the selected regions and regions that affect the traits, as detected by a genome-wide association study. Results showed a low concordance overall between the associated regions and the selected regions. However, markers in associated regions did show larger changes in allele frequencies compared with the average changes across the genome. The selection experiment was performed using a medium density of DNA markers (60K). I subsequently explored the potential benefits of whole-genome sequence data for GS by comparing prediction accuracy from imputed sequence data with the accuracy obtained from the 60K genotypes. Before sequencing, the selection of key animals that should be sequenced to maximize imputation accuracy was assessed with the original 60K genotypes. The accuracy of genotype imputation from lower density panels using a small number of selected key animals as reference was compared with a scenario where random animals were used as the reference population. Even with a very small number of animals as reference, reasonable imputation accuracy could be obtained. Moreover, selecting key animals as reference considerably improved imputation accuracy of rare alleles compared with a set of random reference animals. While imputation from a small reference set was successful, imputation to whole-genome sequence data hardly improved genomic prediction accuracy compared with the predictions based on 60K genotypes. Using only those markers from the whole-genome sequence that are more likely to affect the phenotype was expected to remove noise from the data, but resulted in slightly lower prediction accuracy compared with the complete genome sequence. Finally, I evaluated the inclusion of dominance effects besides additive effects in GS models. The proportion of variance due to additive and dominance effects were estimated for egg production and egg quality traits of a purebred line of layers. The proportion of dominance variance to the total phenotypic variance ranged from 0 to 0.05 across traits. Also, the impact of fitting dominance besides additive effects on prediction accuracy was investigated, but was not found to improve accuracy of genomic prediction of breeding values.

    Breeding against infectious diseases in animals
    Rashidi, H. - \ 2016
    Wageningen University. Promotor(en): Johan van Arendonk, co-promotor(en): Herman Mulder; P.K. Mathur. - Wageningen University - ISBN 9789462576452 - 179
    livestock - infectious diseases - animal breeding - selective breeding - disease resistance - tolerance - genetic variation - breeding value - genetic correlation - traits - genomics - animal genetics - vee - infectieziekten - dierveredeling - selectief fokken - ziekteresistentie - tolerantie - genetische variatie - fokwaarde - genetische correlatie - kenmerken - genomica - diergenetica

    Infectious diseases in farm animals are of major concern because of animal welfare, production costs, and public health. Farms undergo huge economic losses due to infectious disease. The costs of infections in farm animals are mainly due to production losses, treatment of infected animals, and disease control strategies. Control strategies, however, are not always successful. Selective breeding for the animals that can mount a defence against infection could therefore be a promising approach. Defensive ability of an animal has two main mechanisms: resistance (ability to control the pathogen burden) and tolerance (ability to maintain performance when pathogen burden increases). When it is difficult to distinguish between resistance and tolerance, defensive ability is measured as resilience that is the ability to maintain performance during a disease outbreak regardless of pathogen burden. Studies have focused on the genetics of resistance and resilience with little known about the genetics of tolerance and its relationship with resistance and resilience. The objectives of this thesis were to: 1) estimate the genetic variation in resistance, tolerance, and resilience to infection in order to assess the amenability of these traits for selective breeding in farm animals, 2) estimate the genetic correlation between resistance, tolerance and resilience and 3) detect genomic regions associated with resistance, tolerance, and resilience.

    In chapter 2, we studied the variation among sows in response to porcine reproductive and respiratory syndrome (PRRS). First a statistical method was developed to detect PRRS outbreaks based on reproduction records of sows. The method showed a high sensitivity (78%) for disease phases. Then the variation of sows in response to PRRS was quantified using 2 models on the traits number of piglets born alive (NBA) and number of piglets born dead (LOSS): 1) bivariate model considering the trait in healthy and disease phases as different traits, and 2) reaction norm model modelling the response of sows as a linear regression of the trait on herd-year-week estimates of NBA. Trait correlations between healthy and disease phases deviated from unity (0.57±0.13 – 0.87±0.18). The repeatabilities ranged from 0.07±0.027 to 0.16±0.005. The reaction norm model had higher predictive ability in disease phase compared to the bivariate model.

    In chapter 3 we studied 1) the genetic variation in resistance and tolerance of sheep to gastrointestinal nematode infection and 2) the genetic correlation between resistance and tolerance. Sire models on faecal nematode egg count (FEC), IgA, and pepsinogen were used to study the genetic variation in resistance. Heritability for resistance traits ranged from 0.19±0.10 to 0.59±0.20. A random regression model was used to study the reaction norm of sheep body weight on FEC as an estimate of tolerance to nematode infection. We observed a significant genetic variance in tolerance (P<0.05). Finally a bivariate model was used to study the genetic correlation between resistance and tolerance. We observed a negative genetic correlation (-0.63±0.25) between resistance and tolerance.

    In chapter 4, we studied the response to selection in resistance and tolerance when using estimated breeding values for resilience. We used Monte Carlo simulation to generate 100 half-sib families with known breeding values for resistance (pathogen burden) and tolerance. We used selection index theory to predict response to selection for resistance and tolerance: 1) when pathogen burden is known and selection is based on true breeding values for resistance and tolerance and 2) when pathogen burden is unknown and selection is based on estimated breeding values for resilience. Using EBV for resilience in absence of records for pathogen burden resulted in favourable responses in resistance and tolerance to infections, with more emphasis on tolerance than on resistance. However, more genetic gain in resistance and tolerance could be achieved when pathogen burden was known.

    In chapter 5 we studied genomics regions associated with resistance, resilience, and tolerance to PRRS. Resistance was modelled as sire effect on area under the PRRS viremia curve up to 14 days post infection (AUC14). Resilience was modelled as sire effects on daily growth of pigs up to 28 days post infection (ADG28). Tolerance was modelled as the sire effect on the regression of ADG28 on AUC14. We identified a major genomics region on chromosome 4 associated with resistance and resilience to PRRS. We also identified genomics regions on chromosome 1 associated with tolerance to PRRS.

    In the general discussion (chapter 6) I discussed: 1) response to infection as a special case of genotype by environment interaction, 2) random regression model as a statistical tool for studying response to disease, 3) advantages and requirements of random regression models, and 4) selective breeding of farm animals for resistance, tolerance, and resilience to infections. I concluded that random regression is a powerful approach to estimate response to infection in animals. If the adequate amount of data is available random regression model could estimate breeding values of animals more accurately compared to other models. I also concluded that before including resistance and tolerance into breeding programs, breeders should make sure about the added values of including these traits on genetic progress. Selective breeding for resilience could be a pragmatic approach to simultaneously improve resistance and tolerance.

    Multi-population genomic prediction
    Wientjes, Y.C.J. - \ 2016
    Wageningen University. Promotor(en): Roel Veerkamp; Mario Calus. - Wageningen : Wageningen University - ISBN 9789462576193 - 267
    cum laude - dairy cattle - genomics - prediction - quantitative trait loci - genetic improvement - breeding value - selective breeding - animal breeding - animal genetics - melkvee - genomica - voorspelling - loci voor kwantitatief kenmerk - genetische verbetering - fokwaarde - selectief fokken - dierveredeling - diergenetica
    Cum laude graduation
    Hereditary disorders in pedigree dogs and look-a-likes
    Zeeland, C.W.M. Van; Beerda, B. - \ 2015
    Wageningen UR, Wetenschapswinkel (Rapport / Wetenschapswinkel Wageningen UR 317) - ISBN 9789461738882 - 51
    dogs - dog breeds - genetic disorders - pedigree - disease prevalence - animal breeding - animal welfare - animal health - pets - honden - hondenrassen - genetische stoornissen - stamboom - ziekteprevalentie - dierveredeling - dierenwelzijn - diergezondheid - gezelschapsdieren
    Selectie en genetische variatie in een fokprogramma
    Oldenbroek, Kor ; Maurice - Van Eijndhoven, Myrthe - \ 2015
    Zeldzaam huisdier 40 (2015)4. - ISSN 0929-905X - p. 14 - 17.
    dierveredeling - veredelingsprogramma's - genetische variatie - selectie - zeldzame rassen - heritability - inteelt - verwantschap - groninger paard - animal breeding - breeding programmes - genetic variation - selection - rare breeds - heritability - inbreeding - kinship - groningen horse
    In drie voorgaande artikelen in deze serie zijn achtereenvolgens het fokdoel, de registratie van gegevens en de basisprincipes van de erfelijkheid besproken. In dit laatste artikel wordt het belang van genetische variatie en de selectie van ouderdieren besproken. Twee belangrijke elementen in het fokprogramma van een zeldzaam ras.
    Fokkerij nieuwe strategie zonder quotum
    Veerkamp, Roel - \ 2015
    animal breeding - cattle - breeding aims - animal breeding methods - selection - mating - animal genetics
    Handboek melkveehouderij 2015/16
    Remmelink, G.J. ; Middelkoop, J.C. van; Ouweltjes, W. ; Wemmenhove, H. - \ 2015
    Wageningen : Wageningen UR Livestock Research (Handboek / Wageningen UR Livestock Research 30) - 386
    melkvee - melkveehouderij - bodemeigenschappen - bemesting - graslandbeheer - voedergrassen - voedergewassen - rundveevoeding - dierveredeling - diergezondheid - melkproductie - landbouwbedrijfsgebouwen - nederland - handboeken - dairy cattle - dairy farming - soil properties - fertilizer application - grassland management - fodder grasses - fodder crops - cattle feeding - animal breeding - animal health - milk production - farm buildings - netherlands - handbooks
    Natuurlijke antilichamen als voorspeller zieke koe
    Knaap, J. van der; Poel, J.J. van der - \ 2015
    Veeteelt 32 (2015)15. - ISSN 0168-7565 - p. 10 - 12.
    melkveehouderij - dierveredeling - natuurlijke antilichamen - diergezondheid - fokwaarde - dairy farming - animal breeding - natural antibodies - animal health - breeding value
    De aanwezigheid van natuurlijke antilichamen, de zogenaamde NAbs, kan sterk verschillen per koe. Door de erfelijkheidsgraad van NAbs is het mogelijk om erop te fokken, zo blijkt uit het project Weerbaar Vee. De uitkomsten bieden perspectief om de gezondheid te verbeteren, maar de uitvoering lijkt nog niet prakijkrijp.
    Wat is erfelijkheid?
    Maurice - Van Eijndhoven, M.H.T. ; Oldenbroek, Kor - \ 2015
    Zeldzaam huisdier 40 (2015)3. - ISSN 0929-905X - p. 10 - 12.
    heritability - rassen (dieren) - dierveredeling - dna - eigenschappen - spermatozoön - eicellen - bevruchting - genen - allelen - homozygoten - heterozygoten - mutaties - genetische merkers - heritability - breeds - animal breeding - dna - properties - spermatozoa - ova - fertilization - genes - alleles - homozygotes - heterozygotes - mutations - genetic markers
    Eigenschappen van dieren zijn in meer of mindere mate erfelijk. Ze gaan over van ouders op nakomelingen. Maar ervaren fokkers weten dat in de fokkerij 1+1 geen 2 is. Welke wetmatigheden en welke toevalligheden spelen een rol in de erfelijkheid? Wat heeft het DNA-onderzoek ons daar recentelijk over geleerd en wat kunnen we daarmee?
    Genetic background of claw health in dairy cattle
    Spek, D. van der - \ 2015
    Wageningen University. Promotor(en): Johan van Arendonk, co-promotor(en): Henk Bovenhuis. - Wageningen : Wageningen University - ISBN 9789462573475 - 158
    melkvee - klauwen - diergezondheid - voetziekten - genetische parameters - heritability - genomica - selectief fokken - dierveredeling - dairy cattle - claws - animal health - foot diseases - genetic parameters - heritability - genomics - selective breeding - animal breeding

    Abstract

    Van der Spek, D. (2015). Genetic background of claw health in dairy cattle. PhD thesis, Wageningen University, the Netherlands.

    Claw disorders affect cow welfare and profitability of farms and as such are important traits relevant to dairy cattle breeding. Aim of this thesis was to increase our understanding of the genetic background of claw disorders to enable selection for reduced claw disorder incidence. The claw disorders were: abscess, corkscrew claw, (inter-)digital dermatitis or heel erosion (DER), double sole (DS), hardship groove, interdigital hyperplasia (IH), interdigital phlegmon, sand crack, super-foul, sole hemorrhage (SH), sole injury, sole ulcer (SU), white line separation (WLS), and yellow discoloration of the sole. Data was collected on Holstein cows kept in dairy herds in France. Individual claw disorder frequencies ranged from 0.1% to 23.8% and more than half of the trimmed cows had at least one claw disorder in at least one hind leg between 2007 and 2012. Heritabilities were estimated for DER, DS, IH, SH, SU, and WLS, and ranged from 0.02 to 0.14. Repeatabilities ranged from 0.02 to 0.33. The need for trimming (“trimming status”) was found to be heritable as well with a heritability of 0.09. A high need for trimming the claws of cows is unfavorable and therefore trimming status is an interesting trait to include in genetic evaluation. Most claw health traits had similar heritabilities and were genetically the same trait in different parities, lactation stages and herds with different trait frequencies. Claw disorder frequency in Montbeliarde cows ranged from 9.4% to 41.1% and 73% of the cows had at least one claw disorder in at least one hind leg between 2007 and 2013. Heritabilities ranged from 0.01 to 0.09. Heritability for trimming status was 0.06, confirming that trimming status is a heritable trait.

    To identify genomic regions associated with claw disorders and trimming status, a genome wide association study was performed. In total, 11 significant and 46 suggestive SNP were detected. Three of the suggestive SNP could be validated using a dataset of genotyped bulls. The detected SNP were spread across the genome and a major gene was not found.

    In the general discussion, alternative ways of measuring claw disorders were discussed. Accuracy of progeny testing and genomic selection for claw disorders was compared and a breeding program to reduce claw disorders was simulated in order to estimate selection response. Reducing the incidence of claw disorders is achievable with selection, but at a cost of a decrease in production.

    Inteelt-scanner voor rashonden
    Windig, Jack - \ 2015
    breeds - animal genetics - kinship - animal breeding - dogs - animal health - animal welfare - genetic disorders - pets
    Non-genetic variance in pigs: genetic analysis of reproduction and production traits
    Sell-Kubiak, E.B. - \ 2015
    Wageningen University. Promotor(en): Johan van Arendonk, co-promotor(en): Piter Bijma; Herman Mulder. - Wageningen : Wageningen University - ISBN 9789462573291 - 186
    varkens - dierveredeling - voortplanting - dierlijke productie - genetische analyse - genotypische variatie - genomica - fenotypische variatie - pigs - animal breeding - reproduction - animal production - genetic analysis - genetic variance - genomics - phenotypic variation

    Abstract

    Sell-Kubiak, E. (2015). Non-genetic variance in pigs: genetic analysis of reproduction and production traits. PhD thesis, Wageningen University, The Netherlands

    The main objective of this thesis was to study the origin of random variance in reproduction and production traits of pigs. In pig breeding for many traits it is important not only to improve the reproduction and production trait itself, but also its variation. The variance of traits can be used to improve pigs’ productivity, and potentially also to improve uniformity of traits. Results presented in Chapters 2 and 3 show that the proposed approach to explore the origin of common litter variance was not successful. The impact of various sow features on growth rate and feed intake of grow-finish pigs was very small. More importantly, sow features did not explain the phenotypic variance due to common litter effects found in production traits of pigs. In Chapters 4 and 5 the residual variance of birth weight and litter size were found to have a genetic component. The genetic coefficient of variation at residual standard deviation level (GCVSDe) was proposed as a measure of expressing the potential response to selection (Chapter 4). For both traits the estimated GCVSDe was about 10%, indicating sufficient potential for response to selection. In Chapter 4 it was shown that analyzing variation in traits with Double Hierarchical Generalized Linear model (DHGLM) was highly comparable with the conventional analysis of standard deviation of a trait. The correlation between the additive genetic effects for birth weight and the residual variance was 0.6 (Chapter 4), whereas for litter size (TNB) and its residual variance (varTNB) this correlation was 0.5 (Chapter 5). Those moderate correlations are an important indication of the direction of correlated selection response in the mean of those traits. In Chapter 5 in a genome-wide association study for litter size variation, the significant SNPs explained 0.83% of total genetic variance in TNB and 1.44% in varTNB. The most significant SNP explained 0.4% of genetic variance in TNB (chromosome 11) and 0.5% in varTNB (chromosome 7). One of the possible candidate genes for varTNB on chromosome 7 is heat shock protein (HSPCB). Studying the residual variance of traits with DHGLM has a great potential to serve as an alternative to conventional analysis to study and to select for improved uniformity of various traits. Lastly, Chapter 6 focuses on discussion of the findings of this thesis and their overall importance for pig breeding, as well as highly relevant topics for breeding uniform and robust pigs (macro-micro sensitivity analysis and application of genomic selection).

    Genetic improvement in indigenous chicken of Ethiopia
    Woldegiorgiss, W.E. - \ 2015
    Wageningen University. Promotor(en): Johan van Arendonk, co-promotor(en): Liesbeth van der Waaij; T. Dessie. - Wageningen : Wageningen University - ISBN 9789462573161 - 130
    kippen - pluimvee - inheems vee - genetische verbetering - houding van boeren - perceptie - kippenrassen - prestatieniveau - dierveredeling - ethiopië - fowls - poultry - native livestock - genetic improvement - farmers' attitudes - perception - fowl breeds - performance - animal breeding - ethiopia

    Abstract

    Wondmeneh Esatu Woldegiorgiss (2015). Genetic improvement in indigenous chicken of Ethiopia. PhD thesis, Wageningen University, the Netherlands

    This thesis considered various approaches to study the potential for improvement of village poultry production system using improved indigenous chicken. The approaches were structured survey questionnaire, village poultry simulation model (VIPOSIM), Heckman two-step model (econometric model), and experiments involving laboratory and field. First factors that determine the probability and intensity of adoption of exotic chickens were assessed. The probability of adopting exotic chickens was found to be positively affected by access to an off-farm income and negatively by livestock income. The intensity of adoption was negatively affected by being male household head, having a larger farm size, and having livestock income. Then, perceptions of farmers towards village poultry and impacts of interventions on flock and economic performance were assessed. Farmers’ perceptions affected their decisions about implementation of interventions, and interventions increased productivity but only in a few cases the increased revenues outweighed the additional costs. Subsequently, the evaluation of the breeds was conducted by comparing the natural antibody and productivity of improved indigenous chicken with crossbred, commercial and unimproved indigenous chickens. The results revealed that not only the NAb levels but also the effect of NAbs on survival differ between indigenous and improved breeds. NAb levels are associated with survival in commercial layer breed, but reduced survival in indigenous chickens placed in confinement. Improved indigenous chickens showed higher performance than unimproved one for all traits measured on-station, but remains lighter and developed more into a laying type than meat through the short-term selective breeding program. Overall, the present studies indicate that interventions need to be tailored towards the local situation to ensure that they lead not only to improved productivity but also to improved income.

    Breeding program for indigenous chicken in Kenya
    Ngeno, K. - \ 2015
    Wageningen University. Promotor(en): Johan van Arendonk, co-promotor(en): Liesbeth van der Waaij; A.K. Kahi. - Wageningen : Wageningen University - ISBN 9789462572775 - 154
    kippen - pluimvee - inheems vee - dierveredeling - veredelingsprogramma's - genetische diversiteit - ecotypen - genomen - genetische verbetering - kenya - fowls - poultry - native livestock - animal breeding - breeding programmes - genetic diversity - ecotypes - genomes - genetic improvement - kenya

    Abstract

    Ngeno, K. (2015). Breeding program for indigenous chicken in Kenya. Analysis of diversity in indigenous chicken populations. PhD thesis, Wageningen University, the Netherlands

    The objective of this research was to generate knowledge required for the development of an indigenous chicken (IC) breeding program for enhanced productivity and improved human livelihood in Kenya. The initial step was to review five questions; what, why and how should we conserve IC in an effective and sustainable way, who are the stakeholders and what are their roles in the IC breeding program. The next step of the research focused on detecting distinctive IC ecotypes through morphological and genomic characterization. Indigenous chicken ecotypes were found to be populations with huge variability in the morphological features. Molecular characterization was carried out using microsatellite markers and whole genome re-sequenced data. The studied IC ecotypes are genetically distinct groups. The MHC-linked microsatellite markers divided the eight IC ecotypes studied into three mixed clusters, composing of individuals from the different ecotypes whereas non-MHC markers grouped ICs into two groups. Analysis revealed high genetic variation within the ecotype with highly diverse MHC-linked alleles which are known to be involved in disease resistance. Whole genome re-sequencing revealed genomic variability, regions affected by selection, candidate genes and mutations that can explain partially the phenotypic divergence between IC and commercial layers. Unlike commercial chickens, IC preserved a high genomic variability that may be important in addressing present and future challenges associated with environmental adaptation and farmers’ breeding goals. Lastly, this study showed that there is an opportunity to improve IC through selection within the population. Genetic improvement utilizing within IC selection requires setting up a breeding program. The study described the systematic and logical steps in designing a breeding program by focusing on farmers’ need, how to improve IC to fit the farming conditions, and management regimes.

    The hybrid nature of pig genomes : unraveling the mosaic haplotype structure in wild and commercial Sus scrofa populations
    Bosse, M. - \ 2015
    Wageningen University. Promotor(en): Martien Groenen, co-promotor(en): Hendrik-Jan Megens; Ole Madsen. - Wageningen : Wageningen University - ISBN 9789462573000 - 253
    dieren - varkens - dierveredeling - genomen - hybridisatie - sus scrofa - haplotypen - genomica - populaties - genetische variatie - animals - pigs - animal breeding - genomes - hybridization - sus scrofa - haplotypes - genomics - populations - genetic variation - cum laude
    cum laude graduation
    Zeldzame Nederlandse konijnenrassen in de genenbank
    Hoving, A.H. ; Renes, J. ; Taks, A. - \ 2015
    Zeldzaam huisdier 40 (2015)2. - ISSN 0929-905X - p. 20 - 21.
    rassen (dieren) - genetische bronnen van diersoorten - genenbanken - konijnen - zeldzame rassen - dierveredeling - bevruchtingsvermogen - sperma - ingevroren sperma - breeds - animal genetic resources - gene banks - rabbits - rare breeds - animal breeding - fertilizing ability - semen - frozen semen
    In 2014 is van de meeste zeldzame Nederlandse konijnenrassen sperma ingevroren en opgeslagen in de genenbank. Dit kon gerealiseerd worden dankzij samenwerking tussen konijnenfokkers, het Centrum voor Genetische Bronnen Nederland van Wageningen UR (CGN), Kleindier Liefhebbers Nederland (KLN) en de Stichting Zeldzame Huisdierrassen (SZH).
    Leerboek fokkerij en genetica voor het HBO
    Oldenbroek, Kor - \ 2015
    teaching materials - animal breeding - animal genetics - animal breeding methods - livestock farming - professional education - animal welfare - animal health - animal production - pets - dogs - cats - dairy cattle - pigs - poultry - horses
    'Maak risicoanalyse voor het sperma'
    Hoefman, R. ; Veerkamp, R.F. - \ 2015
    Boerderij 100 (2015)28. - ISSN 0006-5617 - p. 44 - 44.
    rundveehouderij - ki stieren - melkveestieren - dierveredeling - genomica - sperma - cattle husbandry - ai bulls - dairy bulls - animal breeding - genomics - semen
    Van het Holstein-sperma is in Nederland ongeveer 50 procent afkomstig van jonge genomicstieren. In Frankrijk is dat 67 procent, in Duitsland 70 procent en in de Scandinavië zelfs 95 procent. Professor numerieke genetica Roel Veer- kamp is bang dat Nederlandse veehouders niet optimaal gebruik maken van de mogelijkheden en kansen laten liggen.
    GReIS en Elda als registratiesystemen voor geitenrassen
    Oldenbroek, J.K. ; Eijndhoven, M.H.T. - \ 2015
    Zeldzaam huisdier 40 (2015)2. - ISSN 0929-905X - p. 16 - 17.
    dierveredeling - rassen (dieren) - zeldzame rassen - geitenrassen - registratie - melkcontrole - computer software - stamboeken - bedrijfsinformatiesystemen - toggenburgergeit - fokwaarde - animal breeding - breeds - rare breeds - goat breeds - registration - milk recording - computer software - herdbooks - management information systems - toggenburg - breeding value
    In een serie artikelen worden de mogelijkheden van registratiesystemen voor zeldzame rassen toegelicht. In dit tweede artikel komt eerst GReIS (GeitenRegistratie- en InformatieSysteem) aan de orde en daarna het Elda-systeem.
    Registreren: meten is weten!
    Maurice - Van Eijndhoven, M.H.T. ; Oldenbroek, J.K. - \ 2015
    Zeldzaam huisdier 40 (2015)2. - ISSN 0929-905X - p. 10 - 11.
    rassen (dieren) - dierveredeling - selectie - registratie - selectief fokken - fenotypen - fokdoelen - stamboeken - databanken - breeds - animal breeding - selection - registration - selective breeding - phenotypes - breeding aims - herdbooks - databases
    Om te kunnen selecteren op bepaalde kenmerken moeten deze ‘meetbaar’
    zijn en worden geregistreerd. Pas dan wordt zichtbaar of er echte
    verbeteringen richting fokdoel worden bereikt in volgende generaties.
    In dit tweede artikel lichten we toe waarom het belangrijk is om goed
    te registeren en hoe een gedegen registratiesysteem eruitziet.
    Erfelijke problemen bij honden los je met fokkerijmaatregelen op!
    Oldenbroek, Kor - \ 2015
    animal welfare - animal health - pets - domestic animals - dogs - animal behaviour - animal breeding - education - genetic disorders - hereditary diseases - dog breeds
    Fokwaarde voeropname : introductie van fokwaarde voor voeropname in Nederland
    Haas, Y. de; Veerkamp, R.F. - \ 2015
    Wageningen : Wageningen UR Livestock Research (Livestock Research rapport 837) - 17
    fokwaarde - melkveehouderij - melkproductie - voeropname - dierveredeling - rundveehouderij - rundveevoeding - breeding value - dairy farming - milk production - feed intake - animal breeding - cattle husbandry - cattle feeding
    Feed costs represent above 50% of the total costs of dairy production, so reducing costs by improving dairy cow feed efficiency is a way to increase profitability. Therefore it is important to improve efficiency of that dairy cattle population. This project has shown that it is possible to breed for more efficient animals, resulting in permanent and cumulative changes in the genetic merit of dairy cows. The breeding value for feed intake is currently integrated in the Better Life Efficiency index for all sires of CRV, and it is under discussing if it will be included in the national index (published by GES) for all bulls in the Netherlands and Flanders.
    Studium Generale “Fairfok the Dog” : oplossing erfelijke rashondenproblematiek; van theorie naar praktijk
    Hopster, Hans - \ 2015
    animal welfare - pets - animal health - animal breeding - education - domestic animals - dogs - dog breeds - hereditary diseases - genetic disorders - animal behaviour
    Vaak scrapieresistentie bij Nederlandse Toggenburgers
    Hoving-Bolink, A.H. ; Windig, J.J. ; Koekoek, A. ; Hoekstra, H. ; Oldenbroek, J.K. ; Langeveld, J. - \ 2015
    Zeldzaam huisdier 40 (2015)1. - ISSN 0929-905X - p. 20 - 21.
    rassen (dieren) - geitenrassen - zeldzame rassen - genetische variatie - scrapie - ziekteresistentie - nederlandse toggenburgergeit - geitenziekten - dierveredeling - toegepast onderzoek - breeds - goat breeds - rare breeds - genetic variation - scrapie - disease resistance - dutch toggenburg - goat diseases - animal breeding - applied research
    Zeldzame Nederlandse rassen zijn niet alleen onderdeel van ons cultureel erfgoed, maar hebben soms ook een verrassende genetische variant. Zo is sinds een paar jaar bekend dat er een allel bestaat dat bescherming biedt tegen scrapie. In onderzoek van Wageningen UR met de geitensector blijkt dat het relatief kleine ras de Nederlandse Toggenburger veel dieren kent met het scrapieresistentie allel.
    ZooEasy als registratiesysteem voor zeldzame rassen
    Oldenbroek, J.K. ; Eijndhoven, M.H.T. - \ 2015
    Zeldzaam huisdier 40 (2015)1. - ISSN 0929-905X - p. 16 - 17.
    dierveredeling - identificatie - zeldzame rassen - rassen (dieren) - hondenrassen - vogels - stamboom - stamboeken - geitenrassen - fokken van kleine dieren - computer software - internet - animal breeding - identification - rare breeds - breeds - dog breeds - birds - pedigree - herdbooks - goat breeds - small animal rearing - computer software - internet
    Nauwkeurige registratie is een vereiste voor een verantwoorde en
    succesvolle fokkerij. Niet alleen speelt afstamming bij zeldzame rassen
    een cruciale rol, fokkers willen ook gegevens over het exterieur
    en de prestaties van de dieren overzichtelijk vastleggen. In deze
    serie worden de mogelijkheden van een aantal systemen toegelicht.
    Het hoe en waarom van een fokprogramma
    Eijndhoven, M.H.T. ; Oldenbroek, J.K. - \ 2015
    Zeldzaam huisdier 40 (2015)1. - ISSN 0929-905X - p. 10 - 11.
    kenmerken - dierveredeling - rassen (dieren) - fokwaarde - fokdoelen - selectiecriteria - traits - animal breeding - breeds - breeding value - breeding aims - selection criteria
    Voor velen van u zal het herkenbaar zijn: verknocht zijn aan een dier om zijn of haar uiterlijk en gedrag. Juist deze kenmerken die horen bij een bepaald ras, wilt u behouden en optimaliseren wanneer u gaat fokken. Verstandig fokken binnen een ras vraagt naast enige kennis van erfelijkheidsleer om het systematisch nalopen van een aantal foktechnische stappen. Deze stappen, die samen het fokprogramma bepalen, komen vanaf dit nummer van Zeldzaam Huisdier in 2015 aan bod.
    Fokkerij op ziekteresistentie van Japanse oesters
    Kamermans, P. ; Engelsma, M.Y. ; Peene, F. ; Blonk, R.J.W. - \ 2015
    Yerseke : IMARES (Rapport / IMARES Wageningen UR C025/15) - 28
    ziekteresistentie - dierveredeling - oesters - nederland - oesterteelt - schaal- en schelpdierenteelt - disease resistance - animal breeding - oysters - netherlands - oyster culture - shellfish culture
    Het oesterherpesvirus OsHV-1 µvar veroorzaakt hoge sterfte onder Japanse oesters in de Nederlandse kweekgebieden. De oestersector ondervindt problemen van deze sterfte. In deze studie is geïnventariseerd of een fokprogramma waarbij oesters geselecteerd worden op resistentie tegen het oesterherpesvirus en vervolgens worden voortgeplant in een hatchery uitkomst kan geven voor deze problematiek. Ook is bekeken of een fokprogramma gebruikt kan worden ter verbetering van groei en conditie van oesters.
    Structural variations in pig genomes
    Paudel, Y. - \ 2015
    Wageningen University. Promotor(en): Martien Groenen, co-promotor(en): Ole Madsen; Hendrik-Jan Megens. - Wageningen : Wageningen University - ISBN 9789462572171 - 204
    varkens - dierveredeling - genomen - genomica - single nucleotide polymorphism - dna-sequencing - fenotypische variatie - chromosoomafwijkingen - evolutie - soortvorming - pigs - animal breeding - genomes - genomics - single nucleotide polymorphism - dna sequencing - phenotypic variation - chromosome aberrations - evolution - speciation

    Abstract

    Paudel, Y. (2015). Structural variations in pig genomes. PhD thesis, Wageningen University, the Netherlands

    Structural variations are chromosomal rearrangements such as insertions-deletions (INDELs), duplications, inversions, translocations, and copy number variations (CNVs). It has been shown that structural variations are as important as single nucleotide polymorphisms (SNPs) in regards to phenotypic variations. The general aim of this thesis was to use next generation sequencing data to improve our understanding of the evolution of structural variations such as CNVs, and INDELs in pigs. We found that: 1) the frequency of copy number variable regions did not change during pig domestications but rather reflected the demographic history of pigs. 2) CNV of olfactory receptor genes seems to play a role in the on-going speciation of the genus Sus. 3) Variation in copy number of olfactory receptor genes in pigs (Sus scrofa) seems to be shaped by a combination of selection and genetic drift, where the clustering of ORs in the genome is the major source of variation in copy number. 4) Analysis on short INDELs in the pig genome shows that the level of purifying selection of INDELs positively correlates with the functional importance of a genomic region, i.e. strongest purifying selection was observed in gene coding regions. This thesis provides a highly valuable resource for copy number variable regions, INDELs, and SNPs, for future pig genetics and breeding research. Furthermore, this thesis discusses the limitations and improvements of the available tools to conduct structural variation analysis and insights into the future trends in the detection of structural variations.

    Speciation and domestication in Suiformes: a genomic perspective
    Frantz, L.A.F. - \ 2015
    Wageningen University. Promotor(en): Martien Groenen, co-promotor(en): Ole Madsen; Hendrik-Jan Megens. - Wageningen : Wageningen University - ISBN 9789462572546 - 227
    domesticatie - suiformes - soortvorming - dierveredeling - genomica - evolutie - genenstroom - dna-sequencing - moleculaire fylogenetica - domestication - suiformes - speciation - animal breeding - genomics - evolution - gene flow - dna sequencing - molecular phylogenetics

    Abstract

    Frantz, L.A.F. (2015). Speciation and Domestication in Suiformes: a genomic perspective. PhD thesis, Wageningen University, the Netherlands

    The diversity of life on earth owes its existence to the process of speciation. The concept of speciation is primordial for evolutionary biologists because it provides a framework to understand how contemporary biodiversity came to be. Moreover, not only natural phenomena can result in the differentiation of life forms. Indeed, biodiversity can also be the result of direct and indirect human influence such as domestication. In this thesis, I investigate these evolutionary processes (speciation and domestication) in the Suiformes superfamily (pigs and related species). I use complete genome sequences to illuminate many specific aspects of the speciation and domestication in Suiformes as well as to draw general conclusions on these crucial processes. In chapter 2 I show how genomes provide an essential source of information to retrieve deep taxonomic relationships among Suiformes. This allows me to describe multiple novel aspects of their early evolutionary history such as the fact that Suiformes colonised North America at least twice. In this chapter, I further highlight and discuss novel methodological limitations that are inherent to phylogenomics. In chapters 3, 4 and 5 I use genome sequences to resolve the evolutionary history of the genus Sus (domestic pigs and wild boars species). More precisely, I show that, contrary to the expectation of simple models of speciation, the evolutionary history of these species involved alternating periods of gene-flow and genetic differentiation that are tightly linked to past climatic fluctuations that took place over the last 4 million years. In addition, these chapters also provide novel insights into the process of speciation by demonstrating that genetic differentiation between species can be achieved, even when gene-flow is strong. Lastly, in chapter 6 I tested multiple models of domestication for S. scrofa. In this chapter I show that models involving reproductive isolation between wild and domestic forms are incompatible with genomic data. Moreover, this chapter demonstrates that, while domestic pigs are morphologically homogenous, they are not genetically homogenous. Together, these findings have important implications for our understanding of the process of domestication because it shows that this process was not solely the result of captivity. Together, the results of this work not only provide a comprehensive evolutionary history for the Suiformes, but also novel insights into the complex processes (speciation and domestication) that are responsible for the diversity of life on earth.

    Textbook animal breeding : animal breeding andgenetics for BSc students
    Oldenbroek, Kor ; Waaij, Liesbeth van der - \ 2014
    Wageningen : Centre for Genetic Resources and Animal Breeding and Genomics Group, Wageningen University and Research Centre - 311
    dierveredeling - selectief fokken - huisdieren - agrarisch onderwijs - diergenetica - lesmaterialen - hoger onderwijs - animal breeding - selective breeding - domestic animals - agricultural education - animal genetics - teaching materials - higher education
    This textbook contains teaching material on animal breeding and genetics for BSc students. The text book started as an initiative of the Dutch Universities for Applied (Agricultural) Sciences. The textbook is made available by the Animal Breeding and Genomics Centre (ABGC) of Wageningen UR (University and Research Centre).
    Een onderzoek naar erfelijke gebreken bij rashonden en lookalikes
    Wageningen UR Wetenschapswinkel, - \ 2014
    Wetenschapswinkel Wageningen UR
    honden - hondenrassen - huisdieren - gezelschapsdieren - dierenwelzijn - diergezondheid - genetische stoornissen - dierveredeling - fokdoelen - dogs - dog breeds - domestic animals - pets - animal welfare - animal health - genetic disorders - animal breeding - breeding aims
    De Stichting Dier & Recht stelt op haar website dat consumenten beter een hond van een kruising uit het asiel kunnen halen, dan voor veel geld een rashond kopen. Rashonden lijken vaker een erfelijk gebrek te hebben, maar is dat echt zo en lopen rashonden dezelfde risico’s als lookalikes?
    Natuurlijke selectie van varroaresistente bijenvolken. Bijennieuws 28
    Blacquière, T. - \ 2014
    Wageningen : Bijen@wur
    apidae - wilde bijenvolken - dierveredeling - rassen (dieren) - ziekteresistentie - selectiemethoden - diergezondheid - varroa - besmetting - mijten - apidae - wild honey bee colonies - animal breeding - breeds - disease resistance - selection methods - animal health - varroa - contamination - mites
    Naar aanleiding van in het wild gevonden (Noord Amerika, Frankrijk) en via experimenten verkregen (Gotland, Zweden) min of meer resistente volken, althans natuurlijk overlevende volken, hebben wij in 2007 met een nateelt van Gotland koninginnen en in 2008 met een Nederlands mengsel van bijenvolken twee teelten van bijenvolken opgezet zonder varroa te bestrijden. Bij de 2008-serie hebben we ook een groep volken als controle meegenomen, waarin varroa twee keer per jaar wordt bestrede
    Handboek melkveehouderij 2014
    Remmelink, G.J. ; Dooren, H.J.C. van; Middelkoop, J.C. van; Ouweltjes, W. ; Wemmenhove, H. - \ 2014
    Wageningen : Wageningen UR Livestock Research (Handboek / Wageningen UR Livestock Research 29) - 385
    melkveehouderij - richtlijnen (guidelines) - naslagwerken - bemesting - graslandbeheer - ruwvoer (forage) - veevoeding - dierveredeling - gezondheid - melkproductie - landbouwbedrijfsgebouwen - bodemwater - agrarisch natuurbeheer - dairy farming - guidelines - reference works - fertilizer application - grassland management - forage - livestock feeding - animal breeding - health - milk production - farm buildings - soil water - agri-environment schemes
    Het Handboek Melkveehouderij is hét naslagwerk voor melkveehouder, agrarisch adviseur, docent en student. De opgenomen informatie is bruikbaar voor de ondersteuning van het dagelijks management én voor het management op de lange termijn.
    Eerste pups outcross Saarlooswolfhond geboren
    Eggink, M. ; Oldenbroek, J.K. - \ 2014
    Zeldzaam huisdier 39 (2014)4. - ISSN 0929-905X - p. 18 - 20.
    hondenrassen - rassen (dieren) - dierveredeling - zeldzame rassen - veredelingsmethoden - puppy's - dog breeds - breeds - animal breeding - rare breeds - breeding methods - puppies
    De Algemene Vereniging van Liefhebbers voor Saarlooswolfhonden (AVLS) heeft een plan van aanpak opgesteld met als doel de hoge onderlinge verwantschap tussen de honden op termijn te laten afnemen. Dat is hard nodig omdat anders de inteelttoename in de toekomst niet meer beheersbaar zal zijn. Gevolgen daarvan zouden zijn dat erfelijke gebreken toenemen en de vruchtbaarheid verder afneemt.
    Genetic management : from science to practice
    Windig, Jack - \ 2014
    animal genetic resources - animal breeding - dogs - kempen heath sheep - veluwe heath sheep - sheep - golden retriever - biodiversity
    The potential of genomic selection to support local breed conservation
    Calus, Mario - \ 2014
    animal breeding - genotypes - phenotypes - genetic variance - genomics - genetic correlation - irish republic - beef cows - animal genetic resources - breeds
    Blaarkopfokplan voor de toekomst : ras van het jaar
    Oldenbroek, J.K. ; Faber, J.H. ; Wieringa, R. - \ 2014
    Zeldzaam huisdier 39 (2014)4. - ISSN 0929-905X - p. 8 - 9.
    rundvee - rundveeteelt - rundveerassen - groninger blaarkop - dierveredeling - fokkerijmethoden - veredelingsprogramma - cattle - cattle farming - cattle breeds - groningen white headed - animal breeding - animal breeding methods - breeding programmes
    Eind 2013 heeft de SZH met de blaarkopbestuurders een strategiedag gehouden. Daaruit kwam onder meer naar voren dat er behoefte is aan een goed en doelgericht fokplan. Onlangs is de Landelijke (Fok)-Commissie begonnen het fokplan uit te werken.
    Fokken en scrapie resistentie bij de Toggenburger geit
    Windig, Jack - \ 2014
    goat keeping - goats - scrapie - dutch toggenburg - toggenburg - goat breeds - disease resistance - animal breeding - rare breeds
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