Application of genetically modified mosquitoes in national vector control programmes: thoughts on integrated control

Abstract

Advances in transgenic technology have allowed the development of genetically transformed insects that have reduced ability to support the development of disease pathogens. The integration of this new method within national vector control programmes is indeed the biggest challenge, notwithstanding the current weak health systems in most disease-endemic countries (DECs) to efficiently apply vector control interventions. Moreover, where integration is considered, it is essential that reliable data are available on the multiple effects of the interventions. This should be done in parallel to the general strengthening of both human, technical, financial and physical resources at all levels of the national health system